Search filters

List of works by Domenico Osella

195Pt NMR spectroscopy: A chemometric approach

A New Entry to Asymmetric Platinum(IV) Complexes via Oxidative Chlorination

scientific article published on 14 August 2014

A multi-methodological inquiry of the behavior of cisplatin-based Pt(IV) derivatives in the presence of bioreductants with a focus on the isolated encounter complexes

scientific article published on 15 April 2020

An unsymmetric cisplatin-based Pt(iv) derivative containing 2-(2-propynyl)octanoate: a very efficient multi-action antitumor prodrug candidate

scientific article published on 6 October 2017

Antiproliferative Activity of Pt(IV) Conjugates Containing the Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) Ketoprofen and Naproxen †

scientific article published on 24 June 2019

Antiproliferative Activity of PtII Complexes with Carboxylated Phosphanes in Chelated or Ring-Opened Forms

Antiproliferative Pt(IV) complexes: synthesis, biological activity, and quantitative structure–activity relationship modeling

article

Antiproliferative activity of Pt(IV)-bis(carboxylato) conjugates on malignant pleural mesothelioma cells

scientific article published on 13 September 2013

Antiproliferative activity of a series of cisplatin-based Pt(IV)-acetylamido/carboxylato prodrugs

scientific article published on 23 February 2016

Antiproliferative effect of ferrocifen drug candidates on malignant pleural mesothelioma cell lines

Authentication and traceability study of hazelnuts from piedmont, Italy.

scientific article published in May 2009

Biological activity of a series of cisplatin-based aliphatic bis(carboxylato) Pt(IV) prodrugs: how long the organic chain should be?

scientific article published on 7 August 2014

Biological activity of enantiomeric complexes [PtCl(2)L (2)] (L (2) is aromatic bisphosphanes and aromatic diamines).

scientific article published on 24 March 2010

Can the Self-Assembling of Dicarboxylate Pt(IV) Prodrugs Influence Their Cell Uptake?

scientific article published on 19 June 2021

Cellular trafficking, accumulation and DNA platination of a series of cisplatin-based dicarboxylato Pt(IV) prodrugs

scientific article published on 27 May 2015

Cis-[Pt(Cl)2(pyridine)(5-SO3H-isoquinoline)] complex, a selective inhibitor of telomerase enzyme.

scientific article published on December 2003

Cisplatin and valproate released from the bifunctional [Pt(IV)Cl2(NH3)2(valproato)2] antitumor prodrug or from liposome formulations: who does what?

scientific article published on 16 January 2017

Cytotoxicity of cis-platinum(II) conjugate models. The effect of chelating arms and leaving groups on cytotoxicity: a quantitative structure-activity relationship approach.

scientific article published on February 2005

Effect of arbuscular mycorrhizal and bacterial inocula on nitrate concentration in mesocosms simulating a wastewater treatment system relying on phytodepuration.

scientific article

Electrochemical Biosensor Assay of the Interaction between [PtCln(NH3)4-n](2-n) (n = 0-4) Complexes and ds-DNA

Electrochemical evaluation of the interaction between antitumoral titanocene dichloride and biomolecules

Electrochemical measurements confirm the preferential bonding of the antimetastatic complex [ImH][RuCl(4)(DMSO)(Im)] (NAMI-A) with proteins and the weak interaction with nucleobases

scientific article

Electrochemical studies of a series of antimetastatic mono- and di-ruthenium complexes [Na][trans-RuIIICl4(DMSO)(L)] and [Na]2[{trans-RuIIICl4(DMSO)}2(μ-L)] (L=N-donor heterocyclic bridging ligand)

Electrostatic Interaction of Negatively Charged Core-Shell Nanoparticles with Antitumoral Cationic Platinum-Based Complexes

Enhancement of the cytotoxicity of titanocene dichloride by aging in organic co-solvent.

scientific article published on 4 October 2005

Estrogen derivatives of transition metal carbonyl clusters for analytical detection enhancement

Estrogen derivatives of transition metal complexes for analytical detection enhancement. Part II

Evaluation of Platinum-Ethacrynic Acid Conjugates in the Treatment of Mesothelioma

scientific article published on 24 October 2011

FACS analysis of oxidative stress induced on tumour cells by SERMs

Functional fluorescent nonporous silica nanoparticles as carriers for Pt(IV) anticancer prodrugs

scientific article published on 6 August 2015

Functionalized nonporous silica nanoparticles as carriers for Pt(iv) anticancer prodrugs.

scientific article published on November 2016

Functionalized thymidine derivatives as carriers for the γ-emitter technetium tricarbonyl moiety

Haemolymph from Mytilus galloprovincialis: Response to copper and temperature challenges studied by (1)H-NMR metabonomics.

scientific article

Host–guest inclusion systems of Pt(IV)-bis(benzoato) anticancer drug candidates and cyclodextrins

Hybrid inorganic (nonporous silica)/organic (alginate) core-shell platform for targeting a cisplatin-based Pt(IV) anticancer prodrug

article published in 2018

In vitro anti-mesothelioma activity of cisplatin-gemcitabine combinations: evidence for sequence-dependent effects

scientific article published on 6 April 2010

Inhibition of Stat3 increases doxorubicin sensitivity in a human metastatic breast cancer cell line

scientific article

May glutamine addiction drive the delivery of antitumor cisplatin-based Pt(IV) prodrugs?

scientific article published on 17 November 2016

Metallo-drugs in the treatment of malignant pleural mesothelioma

Molecular and statistical modeling of reduction peak potential and lipophilicity of platinum(IV) complexes.

scientific article published on 16 November 2010

Molecular interaction fields vs. quantum-mechanical-based descriptors in the modelling of lipophilicity of platinum(IV) complexes.

scientific article published on 21 December 2012

Oxidative degradation of 1,5-naphthalenedisulfonic acid in aqueous solutions by UV-photolysis in the absence and presence of H2O2.

scientific article published on 9 February 2010

Oxidative degradation of 1,5-naphthalenedisulfonic acid in aqueous solutions by microwave irradiation in the presence of H2O2.

scientific article published on 31 December 2008

Oxidative stress and total antioxidant capacity in human plasma

scientific article published on 01 January 2009

Platinum(II) and technetium(I) complexes anchored to ethynylestradiol: a way to drug targeting and delivery

Platinum-bisphosphonate complexes have proven to be inactive chemotherapeutics targeted for malignant mesothelioma because of inappropriate hydrolysis

scientific article published on 30 December 2010

Poly(methylmetacrylate) (PMMA) core–shell nanospheres act as efficient pharmacophores for the antiproliferative [PtCl3(NH3)]− complex by forming ionic couples

Polyanionic Biopolymers for the Delivery of Pt(II) Cationic Antiproliferative Complexes

scientific article published on 28 September 2016

Pros and cons of bifunctional platinum(iv) antitumor prodrugs: two are (not always) better than one

scientific article published on 30 May 2014

Pt(IV) Bifunctional Prodrug Containing 2-(2-Propynyl)octanoato Axial Ligand: Induction of Immunogenic Cell Death on Colon Cancer

scientific article published on 27 March 2019

Radical scavenging abilities of fish MT-A and mussel MT-10 metallothionein isoforms: An ESR study.

scientific article

Reactions of the co-ordinatively unsaturated cluster [Os3(µ-H)(CO)8{Ph2PCH2P(Ph)C6H4}] with alkynes RCCR (R = Ph, C6H4Me, Me or CF3); crystal structures of [Os3(CO)8{µ3–η2(∥)–RC2R}(Ph2PCH2PPh2)](R = Me or CF3) and electrochemical behaviou

Revisiting [PtCl₂(cis-1,4-DACH)]: an underestimated antitumor drug with potential application to the treatment of oxaliplatin-refractory colorectal cancer.

scientific article

Solvolysis of a Series of Cisplatin-Like Complexes - Comparison between DNA-Biosensor and Conductivity Data

Stepwise assembly of platinum–folic acid conjugates

Synthesis and characterisation of estrogenic carriers for cytotoxic Pt(II) fragments: biological activity of the resulting complexes

scientific article published on 22 August 2005

Synthesis and characterization of cyclohexane-1R,2R-diamine-based Pt(iv) dicarboxylato anticancer prodrugs: their selective activity against human colon cancer cell lines

scientific article published on 01 January 2019

Synthesis, characterization and antiproliferative activity on mesothelioma cell lines of bis(carboxylato)platinum(IV) complexes based on picoplatin.

scientific article published on 30 January 2012

Synthesis, characterization, structure, molecular modeling studies and biological activity of sterically crowded Pt(II) complexes containing bis(imidazole) ligands

scientific article published on 14 December 2010

Telomerase inhibition and cancer: might platinum based drugs have a future as anti-telomerase pharmacological approach?

scientific article

The Drug Targeting and Delivery Approach Applied to Pt-Antitumour Complexes. A Coordination Point of View

scientific article published on 01 January 2009

The RP-HPLC measurement and QSPR analysis of logP(o/w) values of several Pt(II) complexes.

scientific article published in July 2006

The activation of platinum(II) antiproliferative drugs in carbonate medium evaluated by means of a DNA-biosensor

scientific article published on 19 April 2007

The cadmium binding domains in the metallothionein isoform Cd(7)-MT10 from Mytilus galloprovincialis revealed by NMR spectroscopy.

scientific article

The cisplatin-based Pt(iv)-diclorofibrato multi-action anticancer prodrug exhibits excellent performances also under hypoxic conditions

scientific article published on 01 June 2018

The hexacarbonyldicobalt derivative of aspirin acts as a CO-releasing NSAID on malignant mesothelioma cells

scientific article published on 9 September 2013

The influence of temperature on antiproliferative effects, cellular uptake and DNA platination of the clinically employed Pt(II)-drugs

scientific article published on 24 October 2007

The relevance of polar surface area (PSA) in rationalizing biological properties of several cis-diamminemalonatoplatinum(II) derivatives

scientific article

Transition metal carbonyl clusters in biology: A futile or niche research area?

Transition metal complexes as electrochemical markers for steroids

Trend in cytotoxic activity of a series of cis-[APtCl2] (A=ethylenediamine methylated at different positions) complexes

Unprecedented one-pot synthesis of an unsymmetrical cisplatin-based Pt(iv)–acetamidato complex

scientific article published on 13 April 2015

Uptake of antitumor platinum(II)-complexes by cancer cells, assayed by inductively coupled plasma mass spectrometry (ICP-MS).

scientific article published on January 2004

Use of Heavy-Metal Clusters in the Design of N-Succinimidyl Ester Acylation Reagents for Side-Chain-Specific Labeling of Proteins

scientific article published on 01 July 1999

Water stability and cytotoxic activity relationship of a series of ferrocenium derivatives. ESR insights on the radical production during the degradation process.

scientific article published on December 2002

Water-soluble benzoheterocycle triosmium clusters as potential inhibitors of telomerase enzyme.

scientific article published in February 2005

trans,cis,cis-bis(benzoato)dichlorido(cyclohexane-1R,2R-diamine)platinum(IV): a prodrug candidate for the treatment of oxaliplatin-refractory colorectal cancer

scientific article published on 8 April 2014

Paulina is supported by:

About Paulina

Help