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List of works by Domenico Osella

1-50 of 78 results

Uptake of antitumor platinum(II)-complexes by cancer cells, assayed by inductively coupled plasma mass spectrometry (ICP-MS).

scientific article published on January 2004

Inhibition of Stat3 increases doxorubicin sensitivity in a human metastatic breast cancer cell line

scientific article

Antiproliferative Pt(IV) complexes: synthesis, biological activity, and quantitative structure–activity relationship modeling

article

The Drug Targeting and Delivery Approach Applied to Pt-Antitumour Complexes. A Coordination Point of View

scientific article published on 01 January 2009

Water stability and cytotoxic activity relationship of a series of ferrocenium derivatives. ESR insights on the radical production during the degradation process.

scientific article published on December 2002

The influence of temperature on antiproliferative effects, cellular uptake and DNA platination of the clinically employed Pt(II)-drugs

scientific article published on 24 October 2007

Electrochemical measurements confirm the preferential bonding of the antimetastatic complex [ImH][RuCl(4)(DMSO)(Im)] (NAMI-A) with proteins and the weak interaction with nucleobases

scientific article

Pros and cons of bifunctional platinum(iv) antitumor prodrugs: two are (not always) better than one

scientific article published on May 30, 2014

The RP-HPLC measurement and QSPR analysis of logP(o/w) values of several Pt(II) complexes.

scientific article published in July 2006

Revisiting [PtCl₂(cis-1,4-DACH)]: an underestimated antitumor drug with potential application to the treatment of oxaliplatin-refractory colorectal cancer.

scientific article

Molecular and statistical modeling of reduction peak potential and lipophilicity of platinum(IV) complexes

scientific article published on 16 November 2010

Cytotoxicity of cis-platinum(II) conjugate models. The effect of chelating arms and leaving groups on cytotoxicity: a quantitative structure-activity relationship approach

scientific article published on February 2005

Antiproliferative activity of Pt(IV)-bis(carboxylato) conjugates on malignant pleural mesothelioma cells

scientific article published on 13 September 2013

Synthesis and characterisation of estrogenic carriers for cytotoxic Pt(II) fragments: biological activity of the resulting complexes

scientific article published on 22 August 2005

Authentication and traceability study of hazelnuts from piedmont, Italy.

scientific article published in May 2009

Cellular trafficking, accumulation and DNA platination of a series of cisplatin-based dicarboxylato Pt(IV) prodrugs

scientific article published on 27 May 2015

Enhancement of the cytotoxicity of titanocene dichloride by aging in organic co-solvent.

scientific article published on 4 October 2005

Molecular interaction fields vs. quantum-mechanical-based descriptors in the modelling of lipophilicity of platinum(IV) complexes.

scientific article published on 21 December 2012

Biological activity of enantiomeric complexes [PtCl(2)L (2)] (L (2) is aromatic bisphosphanes and aromatic diamines).

scientific article published on 24 March 2010

Telomerase inhibition and cancer: might platinum based drugs have a future as anti-telomerase pharmacological approach?

scientific article

A New Entry to Asymmetric Platinum(IV) Complexes via Oxidative Chlorination

scientific article published on 14 August 2014

Biological activity of a series of cisplatin-based aliphatic bis(carboxylato) Pt(IV) prodrugs: how long the organic chain should be?

scientific article published on 7 August 2014

Radical scavenging abilities of fish MT-A and mussel MT-10 metallothionein isoforms: An ESR study.

scientific article

Synthesis, characterization and antiproliferative activity on mesothelioma cell lines of bis(carboxylato)platinum(IV) complexes based on picoplatin.

scientific article published on 30 January 2012

Water-soluble benzoheterocycle triosmium clusters as potential inhibitors of telomerase enzyme.

scientific article published in February 2005

Oxidative stress and total antioxidant capacity in human plasma

scientific article published on 01 January 2009

Antiproliferative activity of a series of cisplatin-based Pt(IV)-acetylamido/carboxylato prodrugs

scientific article published on 23 February 2016

Oxidative degradation of 1,5-naphthalenedisulfonic acid in aqueous solutions by microwave irradiation in the presence of H2O2.

scientific article published on 31 December 2008

Use of Heavy-Metal Clusters in the Design of N-Succinimidyl Ester Acylation Reagents for Side-Chain-Specific Labeling of Proteins

scientific article published on 01 July 1999

Evaluation of Platinum-Ethacrynic Acid Conjugates in the Treatment of Mesothelioma

scientific article published on 24 October 2011

Stepwise assembly of platinum–folic acid conjugates

In vitro anti-mesothelioma activity of cisplatin-gemcitabine combinations: evidence for sequence-dependent effects

scientific article published on 6 April 2010

Antiproliferative effect of ferrocifen drug candidates on malignant pleural mesothelioma cell lines

195Pt NMR spectroscopy: A chemometric approach

The cadmium binding domains in the metallothionein isoform Cd(7)-MT10 from Mytilus galloprovincialis revealed by NMR spectroscopy.

scientific article

trans,cis,cis-bis(benzoato)dichlorido(cyclohexane-1R,2R-diamine)platinum(IV): a prodrug candidate for the treatment of oxaliplatin-refractory colorectal cancer

scientific article published on 8 April 2014

May glutamine addiction drive the delivery of antitumor cisplatin-based Pt(IV) prodrugs?

scientific article published on 17 November 2016

Functional fluorescent nonporous silica nanoparticles as carriers for Pt(IV) anticancer prodrugs

scientific article published on 6 August 2015

The activation of platinum(II) antiproliferative drugs in carbonate medium evaluated by means of a DNA-biosensor

scientific article published on 19 April 2007

Platinum-bisphosphonate complexes have proven to be inactive chemotherapeutics targeted for malignant mesothelioma because of inappropriate hydrolysis

scientific article published on 30 December 2010

The hexacarbonyldicobalt derivative of aspirin acts as a CO-releasing NSAID on malignant mesothelioma cells

scientific article published on 9 September 2013

Cisplatin and valproate released from the bifunctional [Pt(IV)Cl2(NH3)2(valproato)2] antitumor prodrug or from liposome formulations: who does what?

scientific article published on 16 January 2017

Poly(methylmetacrylate) (PMMA) core–shell nanospheres act as efficient pharmacophores for the antiproliferative [PtCl3(NH3)]− complex by forming ionic couples

Functionalized nonporous silica nanoparticles as carriers for Pt(iv) anticancer prodrugs.

scientific article published on November 2016

The relevance of polar surface area (PSA) in rationalizing biological properties of several cis-diamminemalonatoplatinum(II) derivatives

scientific article

Antiproliferative Activity of PtII Complexes with Carboxylated Phosphanes in Chelated or Ring-Opened Forms

Cis-[Pt(Cl)2(pyridine)(5-SO3H-isoquinoline)] complex, a selective inhibitor of telomerase enzyme.

scientific article published on December 2003

Host–guest inclusion systems of Pt(IV)-bis(benzoato) anticancer drug candidates and cyclodextrins

Platinum(II) and technetium(I) complexes anchored to ethynylestradiol: a way to drug targeting and delivery

Oxidative degradation of 1,5-naphthalenedisulfonic acid in aqueous solutions by UV-photolysis in the absence and presence of H2O2.

scientific article published on 9 February 2010