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List of works by Gilles Favre

A new protein-protein interaction sensor based on tripartite split-GFP association

scientific article

A sensitive immunochemiluminescence assay for human serum amyloid A protein

scientific article published on 01 April 1991

Additive effects of tamoxifen and the farnesyl transferase inhibitor FTI-277 on inhibition of MCF-7 breast cancer cell-cycle progression.

scientific article

Basic fibroblast growth factor-2/beta3 integrin expression profile: signature of local progression after chemoradiotherapy for patients with locally advanced non-small-cell lung cancer.

scientific article published on 20 April 2009

Biodistribution study of 99mTc-labeled LDL in B16-melanoma-bearing mice. Visualization of a preferential uptake by the tumor

scientific article published on 01 May 1993

Both farnesylated and geranylgeranylated RhoB inhibit malignant transformation and suppress human tumor growth in nude mice

scientific article published on 01 June 2000

Characteristics of lung cancer in women: importance of hormonal and growth factors.

scientific article

Cloning of the human RHOB gene promoter: characterization of a VNTR sequence that affects transcriptional activity ⬇️

scientific article published on May 1, 2003

Coexpression of CD40L and CD70 by semiallogenic tumor cells induces anti-tumor immunity.

scientific article published on December 2005

Comparative study of the incorporation of ellipticine-esters into low density lipoprotein (LDL) and selective cell uptake of drug--LDL complex via the LDL receptor pathway in vitro

scientific article published on 01 July 1990

Competitive inhibition of choline phosphotransferase by geranylgeraniol and farnesol inhibits phosphatidylcholine synthesis and induces apoptosis in human lung adenocarcinoma A549 cells

scientific article published on 01 October 1998

Contrasting effects of prenyltransferase inhibitors on estrogen-dependent cell cycle progression and estrogen receptor-mediated transcriptional activity in MCF-7 cells.

scientific article published in March 2003

DNA-PK triggers histone ubiquitination and signaling in response to DNA double-strand breaks produced during the repair of transcription-blocking topoisomerase I lesions.

scientific article published on 17 November 2015

Decreased efficiency of MSH6 mRNA polyadenylation linked to a 20-base-pair duplication in Lynch syndrome families.

scientific article published in July 2012

Detection and Monitoring of the BRAF Mutation in Circulating Tumor Cells and Circulating Tumor DNA in BRAF-Mutated Lung Adenocarcinoma

scientific article

Evidence for up-regulated low density lipoprotein receptor in human lung adenocarcinoma cell line A549.

scientific article published on January 1993

Farnesol and geranylgeraniol induce actin cytoskeleton disorganization and apoptosis in A549 lung adenocarcinoma cells

scientific article published on 01 August 1996

Farnesyl transferase inhibitors: one target may be found in another

scientific article published in February 2003

Farnesyl-transferase inhibitor R115,777 enhances tamoxifen inhibition of MCF-7 cell growth through estrogen receptor dependent and independent pathways.

scientific article

Farnesyltransferase inhibitor, R115777, reverses the resistance of human glioma cell lines to ionizing radiation.

scientific article published on July 2002

Formation of the eIF4F translation-initiation complex determines sensitivity to anticancer drugs targeting the EGFR and HER2 receptors.

scientific article published on 15 April 2011

Fuzzy logic selection as a new reliable tool to identify molecular grade signatures in breast cancer--the INNODIAG study

scientific article

Generation of a single chain antibody variable fragment (scFv) to sense selectively RhoB activation

scientific article

Geranylgeranyl transferase inhibition stimulates anti-melanoma immune response through MHC Class I and costimulatory molecule expression.

scientific article published on 29 June 2005

High-content tripartite split-GFP cell-based assays to screen for modulators of small GTPase activation

scientific article published on 30 November 2017

HuR-dependent loading of miRNA RISC to the mRNA encoding the Ras-related small GTPase RhoB controls its translation during UV-induced apoptosis

scientific article

Identification of a Circulating MicroRNA Profile as a Biomarker of Metastatic Cutaneous Melanoma.

scientific article

Importance of mevalonate-derived products in the control of HMG-CoA reductase activity and growth of human lung adenocarcinoma cell line A549.

scientific article

In vivo restoration of RhoB expression leads to ovarian tumor regression.

scientific article

Increased expression of a COOH-truncated nucleophosmin resulting from alternative splicing is associated with cellular resistance to ionizing radiation in HeLa cells.

scientific article published in August 2002

Induction of T-cell antitumor immunity and protection against tumor growth by secretion of soluble human CD70 molecules.

scientific article published on July 2004

Inhibition of Rho pathways induces radiosensitization and oxygenation in human glioblastoma xenografts.

scientific article published on December 2003

Inhibition of human tumor cell growth in vitro and in vivo by a specific inhibitor of human farnesyltransferase: BIM-46068

scientific article published on 01 October 1999

Inhibition of human tumor cell growth in vivo by an orally bioavailable inhibitor of human farnesyltransferase, BIM-46228.

scientific article published on March 2001

Insights into the cholecystokinin 2 receptor binding site and processes of activation

scientific article published on 22 September 2006

Involvement of CD70 and CD80 intracytoplasmic domains in the co-stimulatory signal required to provide an antitumor immune response

scientific article published on 01 March 2003

Involvement of tyrosine kinase activity in the low-density lipoprotein receptor expression in human lung adenocarcinoma cell line A549.

scientific article

Liquid Biopsy of Non-Plasma Body Fluids in Non-Small Cell Lung Cancer: Look Closer to the Tumor!

scientific article published on 16 November 2020

Loss of RhoB expression in human lung cancer progression.

scientific article published on April 2004

Loss of RhoB expression promotes migration and invasion of human bronchial cells via activation of AKT1.

scientific article published on 14 July 2009

MAP1A light chain-2 interacts with GTP-RhoB to control epidermal growth factor (EGF)-dependent EGF receptor signaling

scientific article published on 3 December 2007

Melanoma cells treated with GGTI and IFN-gamma allow murine vaccination and enhance cytotoxic response against human melanoma cells

scientific article

Melanoma-expressed CD70 is involved in invasion and metastasis.

scientific article

Monitoring KRAS mutations in circulating DNA and tumor cells using digital droplet PCR during treatment of KRAS-mutated lung adenocarcinoma.

scientific article published on 22 July 2016

NaLi-H1: A universal synthetic library of humanized nanobodies providing highly functional antibodies and intrabodies.

scientific article

Oncologic trogocytosis of an original stromal cells induces chemoresistance of ovarian tumours

scientific article

Physico-chemical properties and evidence for electrophoretic variants of rat transcortin

scientific article published on 01 May 1984

Preferential cytoplasmic localization of p34cdc2 in recurrent human squamous cell carcinoma after radiotherapy

scientific article published on 01 March 1997

Preferential transfer of certain plasma membrane proteins onto T and B cells by trogocytosis

scientific article

Prenylation inhibitors stimulate both estrogen receptor alpha transcriptional activity through AF-1 and AF-2 and estrogen receptor beta transcriptional activity.

scientific article

Preparation of low density lipoprotein-9-methoxy-ellipticin complex and its cytotoxic effect against L1210 and P 388 leukemic cells in vitro

scientific article published on 01 February 1989

Proliferative effect of high density lipoprotein (HDL) and HDL fractions (HDL1,2, HDL3) on virus transformed lymphoblastoid cells.

scientific article published in September 1989

Reversible dissociation of cortisol-transcortin complex by sodium para-chloromercuribenzoate

scientific article published on 01 December 1983

Reversible inactivation of the transcriptional function of P53 protein by farnesylation.

scientific article published on 29 May 2006

RhoA prenylation is required for promotion of cell growth and transformation and cytoskeleton organization but not for induction of serum response element transcription.

scientific article published on October 2000

RhoB Promotes Cancer Initiation by Protecting Keratinocytes from UVB-Induced Apoptosis but Limits Tumor Aggressiveness ⬇️

scientific article published on June 21, 2013

RhoB determines tumor aggressiveness in a murine EGFRL858R-induced adenocarcinoma model and is a potential prognostic biomarker for Lepidic lung cancer.

scientific article published on 15 October 2014

RhoB loss induces Rac1-dependent mesenchymal cell invasion in lung cells through PP2A inhibition

scientific article published on 6 July 2015

RhoB promotes γH2AX dephosphorylation and DNA double-strand break repair

scientific article

SDF-1alpha concentration dependent modulation of RhoA and Rac1 modifies breast cancer and stromal cells interaction.

scientific article published on August 2015

Serum protein signature may improve detection of ductal carcinoma in situ of the breast

scientific article published on 26 October 2009

Single domain antibodies with VH hallmarks are positively selected during panning of llama (Lama glama) naïve libraries.

scientific article

SupraMolecular BioVectors (SMBV) improve antisense inhibition of erbB-2 expression ⬇️

scientific article published on May 1, 1998

Symbolic data analysis to defy low signal-to-noise ratio in microarray data for breast cancer prognosis.

scientific article

Synthesis and application of a N-1' fluorescent biotinyl derivative inducing the specific carboxy-terminal dual labeling of a novel RhoB-selective scFv.

scientific article

Tamoxifen is a potent inhibitor of cholesterol esterification and prevents the formation of foam cells.

scientific article published on 14 November 2003

Targeted identification of sialoglycoproteins in hypoxic endothelial cells and validation in zebrafish reveal roles for proteins in angiogenesis

scientific article

The RAS-related GTPase RHOB confers resistance to EGFR-tyrosine kinase inhibitors in non-small-cell lung cancer via an AKT-dependent mechanism.

scientific article published on 21 December 2016

The farnesyltransferase inhibitor FTI-277 suppresses the 24-kDa FGF2-induced radioresistance in HeLa cells expressing wild-type RAS

scientific article published on 01 October 1999

The prototypical inhibitor of cholesterol esterification, Sah 58-035 [3-[decyldimethylsilyl]-n-[2-(4-methylphenyl)-1-phenylethyl]propanamide], is an agonist of estrogen receptors.

scientific article published on 11 July 2006

The radioprotective effect of the 24 kDa FGF-2 isoform in HeLa cells is related to an increased expression and activity of the DNA dependent protein kinase (DNA-PK) catalytic subunit.

scientific article published in September 2002

Tipifarnib plus tamoxifen in tamoxifen-resistant metastatic breast cancer: a negative phase II and screening of potential therapeutic markers by proteomic analysis.

scientific article published on 9 February 2010

αvβ3 Integrin and Fibroblast growth factor receptor 1 (FGFR1): Prognostic factors in a phase I-II clinical trial associating continuous administration of Tipifarnib with radiotherapy for patients with newly diagnosed glioblastoma

scientific article published on 6 April 2013

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