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List of works by Joseph W Lynch

A Chemogenetic Receptor That Enhances the Magnitude and Frequency of Glycinergic Inhibitory Postsynaptic Currents without Inducing a Tonic Chloride Flux

scientific article published on 15 December 2016

A lipid site shapes the agonist response of a pentameric ligand-gated ion channel

scientific article published on 07 October 2019

A novel anticonvulsant mechanism via inhibition of complement receptor C5ar1 in murine epilepsy models

scientific article published on 11 February 2015

A novel glycine receptor variant with startle disease affects syndapin I and glycinergic inhibition

scientific article published on 29 April 2020

Author Correction: Hippocampus-driven feed-forward inhibition of the prefrontal cortex mediates relapse of extinguished fear

scientific article published on 01 September 2018

Disruption of a Structurally Important Extracellular Element in the Glycine Receptor Leads to Decreased Synaptic Integration and Signaling Resulting in Severe Startle Disease

scientific article published on 19 July 2017

Effects of GluN2A and GluN2B gain-of-function epilepsy mutations on synaptic currents mediated by diheteromeric and triheteromeric NMDA receptors

scientific article published on 01 April 2020

Effects of glutamate and ivermectin on single glutamate-gated chloride channels of the parasitic nematode H. contortus

scientific article published on 2 October 2017

Functional characterization of ivermectin binding sites in α1β2γ2L GABA(A) receptors

scientific article

Generation of Functional Inhibitory Synapses Incorporating Defined Combinations of GABA(A) or Glycine Receptor Subunits.

scientific article

GluClR-mediated inhibitory postsynaptic currents reveal targets for ivermectin and potential mechanisms of ivermectin resistance

scientific article published on 29 January 2019

Hippocampus-driven feed-forward inhibition of the prefrontal cortex mediates relapse of extinguished fear

scientific article

Investigating ion channel conformational changes using voltage clamp fluorometry.

scientific article

Investigating the Mechanism by Which Gain-of-function Mutations to the α1 Glycine Receptor Cause Hyperekplexia

scientific article published on 18 May 2016

Physiological and pharmacological properties of inhibitory postsynaptic currents mediated by α5β1γ2, α5β2γ2 and α5β3γ2 GABAA receptors

scientific article

Potent neuroprotection after stroke afforded by a double-knot spider-venom peptide that inhibits acid-sensing ion channel 1a.

scientific article published on 20 March 2017

Probing the Structural Mechanism of Partial Agonism in Glycine Receptors Using the Fluorescent Artificial Amino Acid, ANAP.

scientific article published on 25 January 2017

Shisa7 is a GABAA receptor auxiliary subunit controlling benzodiazepine actions

scientific article

Xenopus borealis as an alternative source of oocytes for biophysical and pharmacological studies of neuronal ion channels.

scientific article

Zolpidem and eszopiclone prime α1β2γ2 GABAA receptors for longer duration of activity

scientific article published on 11 May 2015

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