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List of works by Martine Jandrot-Perrus

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Deficiency in the Wiskott-Aldrich protein induces premature proplatelet formation and platelet production in the bone marrow compartment

scientific article
Deletion of the p110 isoform of phosphoinositide 3-kinase in platelets reveals its central role in Akt activation and thrombus formation in vitro and in vivo

scientific article published on 11 January 2010
Cloning, characterization, and functional studies of human and mouse glycoprotein VI: a platelet-specific collagen receptor from the immunoglobulin superfamily

scientific article (publication date: September 2000)
Single platelets seal neutrophil-induced vascular breaches via GPVI during immune-complex-mediated inflammation in mice.

scientific article
Bothrojaracin, a new thrombin inhibitor isolated from Bothrops jararaca venom: characterization and mechanism of thrombin inhibition

scientific article published on 01 October 1993
Roles of the C-terminal tyrosine residues of LAT in GPVI-induced platelet activation: insights into the mechanism of PLC gamma 2 activation

scientific journal article
Absence of collagen-induced platelet activation caused by compound heterozygous GPVI mutations

scientific article published on 23 June 2009
Adhesion and activation of human platelets induced by convulxin involve glycoprotein VI and integrin alpha2beta1

scientific article published on 01 October 1997
Radiolabeled fucoidan as a p-selectin targeting agent for in vivo imaging of platelet-rich thrombus and endothelial activation

scientific article published on 17 August 2011
Platelet Glycoprotein VI Dimerization, an Active Process Inducing Receptor Competence, Is an Indicator of Platelet Reactivity

scientific article published in March 2012
Differential regulation of actin stress fiber assembly and proplatelet formation by alpha2beta1 integrin and GPVI in human megakaryocytes

scientific article published on 20 July 2004
Phosphorothioate backbone modifications of nucleotide-based drugs are potent platelet activators

scientific article
Platelet activation and aggregation promote lung inflammation and influenza virus pathogenesis.

scientific article published on April 2015
Exploring the platelet proteome via combinatorial, hexapeptide ligand libraries

scientific article
Enhancement of the synthesis and secretion of nerve growth factor in primary cultures of glial cells by proteases: a possible involvement of thrombin.

scientific article published in March 1993
Emerging role of serpinE2/protease nexin-1 in hemostasis and vascular biology.

scientific article published on 10 January 2012
Protease-activating Receptor-4 Induces Full Platelet Spreading on a Fibrinogen Matrix

scientific article published on 02 January 2007
Severe deficiency of glycoprotein VI in a patient with gray platelet syndrome.

scientific article published on 9 March 2004
Non-invasive molecular imaging of fibrosis using a collagen-targeted peptidomimetic of the platelet collagen receptor glycoprotein VI

scientific article published on 18 May 2009
Alteplase Reduces Downstream Microvascular Thrombosis and Improves the Benefit of Large Artery Recanalization in Stroke

scientific article published on 6 October 2015
Costimulation of the Gi-coupled ADP receptor and the Gq-coupled TXA2 receptor is required for ERK2 activation in collagen-induced platelet aggregation.

scientific article
The future of glycoprotein VI as an antithrombotic target.

scientific article published on December 2012
Affinity of low molecular weight fucoidan for P-selectin triggers its binding to activated human platelets

scientific article
Heterogeneity of platelet functional alterations in patients with filamin A mutations.

scientific article
Anticoagulant and antithrombotic properties of platelet protease nexin-1

scientific article
Platelet Protease Nexin-1, a Serpin That Strongly Influences Fibrinolysis and Thrombolysis

scientific article published on March 14, 2011
Protease nexin-1 interacts with thrombomodulin and modulates its anticoagulant effect

scientific article
Identification of residues within human glycoprotein VI involved in the binding to collagen: evidence for the existence of distinct binding sites.

scientific article published on 4 October 2004
Bothrojaracin: a potent two-site-directed thrombin inhibitor

scientific article published on 01 July 1996
Glycoprotein Ib-mediated platelet activation. A signalling pathway triggered by thrombin.

scientific article published in July 2003
Molecular Cloning and Expression of Bothrojaracin, A Potent Thrombin Inhibitor from Snake Venom

scientific article published on 01 September 1997
Hemostatic disorders in a JAK2V617F-driven mouse model of myeloproliferative neoplasm

scientific article
Protease nexin-1: a cellular serpin down-regulated by thrombin in rat aortic smooth muscle cells

scientific journal article
Switch from protective to adverse inflammation during influenza: viral determinants and hemostasis are caught as culprits

scientific article
Design and humanization of a murine scFv that blocks human platelet glycoprotein VI in vitro

scientific article published on 25 June 2009
Platelet activation induces metalloproteinase-dependent GP VI cleavage to down-regulate platelet reactivity to collagen

scientific article published on 31 August 2004
Thrombin receptor induction by injury-related factors in human skeletal muscle cells.

scientific article
Distinct spatio-temporal Ca2+ signaling elicited by integrin alpha2beta1 and glycoprotein VI under flow.

scientific article published on 21 July 2009
Contribution of platelet glycoprotein VI to the thrombogenic effect of collagens in fibrous atherosclerotic lesions

scientific article published on 12 February 2005
Expression and function of the collagen receptor GPVI during megakaryocyte maturation.

scientific article
Human platelet glycoprotein VI function is antagonized by monoclonal antibody-derived Fab fragments

scientific article published on 01 December 2003
Cross-linking of alpha and gamma-thrombin to distinct binding sites on human platelets

scientific article published on 01 June 1988
The Serpin Protease-Nexin 1 Is Present in Rat Aortic Smooth Muscle Cells and Is Upregulated in l -NAME Hypertensive Rats

scientific article published on 01 January 2003
Macrophages and Platelets Are the Major Source of Protease Nexin-1 in Human Atherosclerotic Plaque

scientific article published on 10 July 2008
Protease nexin I expression is up-regulated in human skeletal muscle by injury-related factors

scientific article published on 01 June 1999
Dilation-Dependent Activation of Platelets and Prothrombin in Human Thoracic Ascending Aortic Aneurysm

scientific article published in May 2008
In vitro and in vivo antiangiogenic properties of the serpin protease nexin-1

scientific article published on 13 February 2012
A humanized glycoprotein VI (GPVI) mouse model to assess the antithrombotic efficacies of anti-GPVI agents.

scientific article
Ex vivo inhibition of thrombus formation by an anti-glycoprotein VI Fab fragment in non-human primates without modification of glycoprotein VI expression

scientific article published on 14 April 2008
Phosphatidylinositol 3'-kinase and tyrosine-phosphatase activation positively modulate Convulxin-induced platelet activation. Comparison with collagen

scientific article published on 01 April 1999

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