List of works - Francesco Frecentese

1,2,4-Thiadiazolidin-3,5-diones as novel hydrogen sulfide donors.

scientific article published on 10 November 2017

5-HT(1A) receptor: an old target as a new attractive tool in drug discovery from central nervous system to cancer

scientific article published on 10 December 2013

A suitable 1,2,4-oxadiazoles synthesis by microwave irradiation

scientific article published on 01 September 2004

Development of 1,2,3-Triazole-Based Sphingosine Kinase Inhibitors and Their Evaluation as Antiproliferative Agents.

scientific article published on 5 November 2017

Efficient microwave combinatorial parallel and nonparallel synthesis of N-alkylated glycine methyl esters as peptide building blocks.

scientific article published in July 2005

Efficient microwave combinatorial synthesis of novel indolic arylpiperazine derivatives as serotoninergic ligands.

scientific article

Fragment-based de novo design of a cystathionine γ-lyase selective inhibitor blocking hydrogen sulfide production

scientific article published on 6 October 2016

Identification of a pepducin acting as S1P3 receptor antagonist.

scientific article published on 20 September 2013

Inhibition of rat vas deferens contractions by flavonoids in-vitro

scientific article published in March 2006

Kallikrein protease activated receptor (PAR) axis: an attractive target for drug development

scientific article

Lipophilic and polar interaction forces between acidic drugs and membrane phospholipids encoded in IAM-HPLC indexes: their role in membrane partition and relationships with BBB permeation data

scientific article

Microwave Assisted Organic Synthesis of Heterocycles in Aqueous Media: Recent Advances in Medicinal Chemistry

scientific article published on 2 May 2016

Microwave assisted synthesis: a new technology in drug discovery.

scientific article published on March 2009

New 5-HT(1A) receptor ligands containing a N'-cyanoisonicotinamidine nucleus: synthesis and in vitro pharmacological evaluation

scientific article published on 3 March 2010

New 5-HT1A, 5HT2A and 5HT2C receptor ligands containing a picolinic nucleus: Synthesis, in vitro and in vivo pharmacological evaluation

scientific article

New potent 5-HT2A receptor ligands containing an N′-cyanopicolinamidine nucleus: Synthesis and in vitro pharmacological evaluation

scientific article published on 20 November 2011

Propylthiouracil quantification in human plasma by high-performance liquid chromatography coupled with electrospray tandem mass spectrometry: Application in a bioequivalence study

scientific article published on 07 August 2014

Quantification of dapaconazole in human plasma using high-performance liquid chromatography coupled to tandem mass spectrometry: Application to a phase I study

scientific article published on 12 March 2014

Synthesis and in Vitro Screening of New Series of 2,6-Dipeptidyl-anthraquinones: Influence of Side Chain Length on HIV-1 Nucleocapsid Inhibitors.

scientific article published on 22 January 2016

Synthesis and in vitro pharmacological evaluation of novel 2-hydroxypropyl-4-arylpiperazine derivatives as serotoninergic ligands

scientific article published on 11 August 2014

Synthesis and in-vitro pharmacological evaluation of new 5-HT1A receptor ligands containing a benzotriazinone nucleus.

scientific article published in January 2008

Synthesis and pharmacological evaluation of peptide-mimetic protease-activated receptor-1 antagonists containing novel heterocyclic scaffolds.

scientific article published on 26 April 2008

Synthesis and pharmacological evaluations of sildenafil analogues for treatment of erectile dysfunction.

scientific article

Synthesis by microwave irradiation and antidiarrhoeal activity of benzotriazinone and saccharine derivatives

scientific article

Synthesis of 1-naphtylpiperazine derivatives as serotoninergic ligands and their evaluation as antiproliferative agents

scientific article published on 08 March 2011

Synthesis of Arylpiperazine Derivatives as Protease Activated Receptor 1 Antagonists and Their Evaluation as Antiproliferative Agents.

scientific article published on 26 September 2016

Synthesis of benzamide derivatives and their evaluation as antiprion agents

scientific article

Synthesis ofN α-FmocN,N′-bis-Boc-5-, 6- and 8-guanyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic Acid (5-GTIC, 6-GTIC and 8-GTIC)

article

Synthesis, biological evaluation, and docking studies of PAR2-AP-derived pseudopeptides as inhibitors of kallikrein 5 and 6

scientific article published on 01 January 2015

Synthesis, in vitro and in vivo pharmacological evaluation of serotoninergic ligands containing an isonicotinic nucleus

scientific article published on 18 January 2016

List of works by Francesco Frecentese

1,2,4-Thiadiazolidin-3,5-diones as novel hydrogen sulfide donors.

5-HT(1A) receptor: an old target as a new attractive tool in drug discovery from central nervous system to cancer

A suitable 1,2,4-oxadiazoles synthesis by microwave irradiation

Development of 1,2,3-Triazole-Based Sphingosine Kinase Inhibitors and Their Evaluation as Antiproliferative Agents.

Efficient microwave combinatorial parallel and nonparallel synthesis of N-alkylated glycine methyl esters as peptide building blocks.

Efficient microwave combinatorial synthesis of novel indolic arylpiperazine derivatives as serotoninergic ligands.

Fragment-based de novo design of a cystathionine γ-lyase selective inhibitor blocking hydrogen sulfide production

Identification of a pepducin acting as S1P3 receptor antagonist.

Inhibition of rat vas deferens contractions by flavonoids in-vitro

Kallikrein protease activated receptor (PAR) axis: an attractive target for drug development

Lipophilic and polar interaction forces between acidic drugs and membrane phospholipids encoded in IAM-HPLC indexes: their role in membrane partition and relationships with BBB permeation data

Microwave Assisted Organic Synthesis of Heterocycles in Aqueous Media: Recent Advances in Medicinal Chemistry

Microwave assisted synthesis: a new technology in drug discovery.

New 5-HT(1A) receptor ligands containing a N'-cyanoisonicotinamidine nucleus: synthesis and in vitro pharmacological evaluation

New 5-HT1A, 5HT2A and 5HT2C receptor ligands containing a picolinic nucleus: Synthesis, in vitro and in vivo pharmacological evaluation

New potent 5-HT2A receptor ligands containing an N′-cyanopicolinamidine nucleus: Synthesis and in vitro pharmacological evaluation

Propylthiouracil quantification in human plasma by high-performance liquid chromatography coupled with electrospray tandem mass spectrometry: Application in a bioequivalence study

Quantification of dapaconazole in human plasma using high-performance liquid chromatography coupled to tandem mass spectrometry: Application to a phase I study

Synthesis and in Vitro Screening of New Series of 2,6-Dipeptidyl-anthraquinones: Influence of Side Chain Length on HIV-1 Nucleocapsid Inhibitors.

Synthesis and in vitro pharmacological evaluation of novel 2-hydroxypropyl-4-arylpiperazine derivatives as serotoninergic ligands

Synthesis and in-vitro pharmacological evaluation of new 5-HT1A receptor ligands containing a benzotriazinone nucleus.

Synthesis and pharmacological evaluation of peptide-mimetic protease-activated receptor-1 antagonists containing novel heterocyclic scaffolds.

Synthesis and pharmacological evaluations of sildenafil analogues for treatment of erectile dysfunction.

Synthesis by microwave irradiation and antidiarrhoeal activity of benzotriazinone and saccharine derivatives

Synthesis of 1-naphtylpiperazine derivatives as serotoninergic ligands and their evaluation as antiproliferative agents

Synthesis of Arylpiperazine Derivatives as Protease Activated Receptor 1 Antagonists and Their Evaluation as Antiproliferative Agents.

Synthesis of benzamide derivatives and their evaluation as antiprion agents

Synthesis ofN α-FmocN,N′-bis-Boc-5-, 6- and 8-guanyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic Acid (5-GTIC, 6-GTIC and 8-GTIC)

Synthesis, biological evaluation, and docking studies of PAR2-AP-derived pseudopeptides as inhibitors of kallikrein 5 and 6

Synthesis, in vitro and in vivo pharmacological evaluation of serotoninergic ligands containing an isonicotinic nucleus