List of works - Li F Chan

ACTH Antagonists

scientific article

ACTH signalling and adrenal development: lessons from mouse models

scientific article published on 01 July 2019

Advances in the management of paediatric Cushing's disease

scientific article published on 17 March 2008

Central role for melanocortin-4 receptors in offspring hypertension arising from maternal obesity

scientific article published on 06 October 2016

Diagnosis and treatment of Cushing's disease in children.

scientific article

Diagnosis and treatment of pediatric Cushing's disease.

scientific article published on January 2007

Diagnosis, management and therapeutic outcome in prepubertal Cushing's disease.

scientific article

Distinct melanocortin 2 receptor accessory protein domains are required for melanocortin 2 receptor interaction and promotion of receptor trafficking.

scientific article published on 25 September 2008

Genetic Analysis of Pediatric Primary Adrenal Insufficiency of Unknown Etiology: 25 Years' Experience in the UK

scientific article published on 11 May 2021

Isolated Addison's disease is unlikely to be caused by mutations in MC2R, MRAP or STAR, three genes responsible for familial glucocorticoid deficiency

scientific article

Isolated glucocorticoid deficiency: Genetic causes and animal models

scientific article published on 25 February 2019

Localisation of the melanocortin-2-receptor and its accessory proteins in the developing and adult adrenal gland

scientific article

Loss of Mrap2 is associated with Sim1 deficiency and increased circulating cholesterol.

scientific article published on 22 April 2016

MRAP and MRAP2 are bidirectional regulators of the melanocortin receptor family

scientific article

MRAP deficiency impairs adrenal progenitor cell differentiation and gland zonation

scientific article published on 07 June 2018

Melanocortin receptor accessory proteins in adrenal disease and obesity

scientific article

Melanocortin receptor accessory proteins in adrenal gland physiology and beyond.

scientific article

NNT pseudoexon activation as a novel mechanism for disease in two siblings with familial glucocorticoid deficiency

scientific article

Neonatal presentation of familial glucocorticoid deficiency resulting from a novel splice mutation in the melanocortin 2 receptor accessory protein.

scientific article published on 27 September 2011

Overexpression of melanocortin 2 receptor accessory protein 2 (MRAP2) in adult paraventricular MC4R neurons regulates energy intake and expenditure

scientific article published on 04 October 2018

Paediatric Cushing's syndrome: epidemiology, investigation and therapeutic advances.

scientific article published on 6 April 2007

Pathophysiology of melanocortin receptors and their accessory proteins

scientific article published on 09 February 2018

Pediatric Cushing's syndrome: clinical features, diagnosis, and treatment.

scientific article

Promiscuity among the MRAPs

scientific article published on 17 February 2017

Pseudo-precocious puberty caused by a juvenile granulosa cell tumour secreting androstenedione, inhibin and insulin-like growth factor-I.

scientific article

Stability and Turnover of the ACTH Receptor Complex

scientific article published on 26 July 2019

The genetics of familial glucocorticoid deficiency.

scientific article published on April 2009

The majority of adrenocorticotropin receptor (melanocortin 2 receptor) mutations found in familial glucocorticoid deficiency type 1 lead to defective trafficking of the receptor to the cell surface.

scientific article published on 7 October 2008

The melanocortin receptors and their accessory proteins.

scientific article published on 8 February 2013

Thioredoxin Reductase 2 (TXNRD2) mutation associated with familial glucocorticoid deficiency (FGD).

scientific article

Use of intravenous etomidate to control acute psychosis induced by the hypercortisolaemia in severe paediatric Cushing's disease.

scientific article

Whole-Exome Sequencing in the Differential Diagnosis of Primary Adrenal Insufficiency in Children

scientific article published on 5 August 2015

Work-up and management of paediatric Cushing's syndrome.

scientific article published on August 2008

List of works by Li F Chan

ACTH Antagonists

ACTH signalling and adrenal development: lessons from mouse models

Advances in the management of paediatric Cushing's disease

Central role for melanocortin-4 receptors in offspring hypertension arising from maternal obesity

Diagnosis and treatment of Cushing's disease in children.

Diagnosis and treatment of pediatric Cushing's disease.

Diagnosis, management and therapeutic outcome in prepubertal Cushing's disease.

Distinct melanocortin 2 receptor accessory protein domains are required for melanocortin 2 receptor interaction and promotion of receptor trafficking.

Genetic Analysis of Pediatric Primary Adrenal Insufficiency of Unknown Etiology: 25 Years' Experience in the UK

Isolated Addison's disease is unlikely to be caused by mutations in MC2R, MRAP or STAR, three genes responsible for familial glucocorticoid deficiency

Isolated glucocorticoid deficiency: Genetic causes and animal models

Localisation of the melanocortin-2-receptor and its accessory proteins in the developing and adult adrenal gland

Loss of Mrap2 is associated with Sim1 deficiency and increased circulating cholesterol.

MRAP and MRAP2 are bidirectional regulators of the melanocortin receptor family

MRAP deficiency impairs adrenal progenitor cell differentiation and gland zonation

Melanocortin receptor accessory proteins in adrenal disease and obesity

Melanocortin receptor accessory proteins in adrenal gland physiology and beyond.

NNT pseudoexon activation as a novel mechanism for disease in two siblings with familial glucocorticoid deficiency

Neonatal presentation of familial glucocorticoid deficiency resulting from a novel splice mutation in the melanocortin 2 receptor accessory protein.

Overexpression of melanocortin 2 receptor accessory protein 2 (MRAP2) in adult paraventricular MC4R neurons regulates energy intake and expenditure

Paediatric Cushing's syndrome: epidemiology, investigation and therapeutic advances.

Pathophysiology of melanocortin receptors and their accessory proteins

Pediatric Cushing's syndrome: clinical features, diagnosis, and treatment.

Promiscuity among the MRAPs

Pseudo-precocious puberty caused by a juvenile granulosa cell tumour secreting androstenedione, inhibin and insulin-like growth factor-I.

Stability and Turnover of the ACTH Receptor Complex

The genetics of familial glucocorticoid deficiency.

The majority of adrenocorticotropin receptor (melanocortin 2 receptor) mutations found in familial glucocorticoid deficiency type 1 lead to defective trafficking of the receptor to the cell surface.

The melanocortin receptors and their accessory proteins.

Thioredoxin Reductase 2 (TXNRD2) mutation associated with familial glucocorticoid deficiency (FGD).

Use of intravenous etomidate to control acute psychosis induced by the hypercortisolaemia in severe paediatric Cushing's disease.

Whole-Exome Sequencing in the Differential Diagnosis of Primary Adrenal Insufficiency in Children

Work-up and management of paediatric Cushing's syndrome.