Search filters

List of works by Mong-Hong Lee

14-3-3sigma, a p53 regulator, suppresses tumor growth of nasopharyngeal carcinoma.

scientific article published in February 2006

14-3-3σ Exerts Tumor-Suppressor Activity Mediated by Regulation of COP1 Stability ⬇️

scientific article published on December 6, 2010

14-3-3σ Positively Regulates p53 and Suppresses Tumor Growth ⬇️

scientific article published on October 1, 2003

A hypoxia-responsive TRAF6-ATM-H2AX signalling axis promotes HIF1α activation, tumorigenesis and metastasis

scientific article published on 05 December 2016

Ablation of the CDK inhibitor p57Kip2 results in increased apoptosis and delayed differentiation during mouse development.

scientific article published in April 1997

Anti-HER2 antibody trastuzumab inhibits CDK2-mediated NPAT and histone H4 expression via the PI3K pathway.

scientific article

Association of the cyclin-dependent kinases and 14-3-3 sigma negatively regulates cell cycle progression

scientific article

Aurora-B kinase inhibitors for cancer chemotherapy.

scientific article published on December 2008

COP1 enhances ubiquitin-mediated degradation of p27Kip1 to promote cancer cell growth.

scientific article

COP9 signalosome subunit 6 (CSN6) regulates E6AP/UBE3A in cervical cancer

scientific article

COP9 signalosome subunit 6 stabilizes COP1, which functions as an E3 ubiquitin ligase for 14-3-3σ

scientific article

CSN6 deregulation impairs genome integrity in a COP1-dependent pathway

scientific article published in May 2015

CSN6 drives carcinogenesis by positively regulating Myc stability.

scientific article

CSN6 positively regulates c-Jun in a MEKK1-dependent manner

scientific article published on 3 August 2015

CSN6-COP1 axis in cancer

scientific article published on 8 July 2015

Cancer metabolic reprogramming: importance, main features, and potentials for precise targeted anti-cancer therapies

scientific article

Circadian Clock Gene CRY2 Degradation Is Involved in Chemoresistance of Colorectal Cancer.

scientific article published on 8 April 2015

Clinical characteristics, microbiology, and outcomes for patients with lung and disseminated nocardiosis in a tertiary hospital.

scientific article published on 3 September 2013

Constitutively active FOXO4 inhibits Akt activity, regulates p27 Kip1 stability, and suppresses HER2-mediated tumorigenicity

scientific article

Correlation of p27 protein expression with HER-2/neu expression in breast cancer.

scientific article published on March 2001

DNA damage-induced protein 14-3-3 sigma inhibits protein kinase B/Akt activation and suppresses Akt-activated cancer.

scientific article published in March 2006

Diabetes mellitus type 2 drives metabolic reprogramming to promote pancreatic cancer growth

scientific article published on 27 May 2020

EGF Relays Signals to COP1 and Facilitates FOXO4 Degradation to Promote Tumorigenesis

scientific article published on 23 September 2020

ERK2-Dependent Phosphorylation of CSN6 Is Critical in Colorectal Cancer Development

scientific journal article

Effects of obesity on transcriptomic changes and cancer hallmarks in estrogen receptor-positive breast cancer

scientific article

FBXW7 is involved in Aurora B degradation.

scientific article

Farnesyltransferase inhibitors-induced autophagy: alternative mechanisms?

scientific article

HER2-Akt signaling in regulating COP9 signalsome subunit 6 and p53 ⬇️

scientific article published on October 24, 2012

Hepatocyte Growth Factor/cMET Pathway Activation Enhances Cancer Hallmarks in Adrenocortical Carcinoma.

scientific article

ILF3 is a substrate of SPOP for regulating serine biosynthesis in colorectal cancer

scientific article published on 26 November 2019

Intercepting Akt with DNAzyme: a nasopharyngeal carcinoma story

scientific article published on 05 February 2009

Maintenance Therapy Containing Metformin and/or Zyflamend for Advanced Prostate Cancer: A Case Series

scientific article

Metformin and thiazolidinediones are associated with improved breast cancer-specific survival of diabetic women with HER2+ breast cancer.

scientific article

Modified p27 Kip1 is efficient in suppressing HER2-mediated tumorigenicity.

scientific article published on May 2006

Multi-gene fluorescence in situ hybridization to detect cell cycle gene copy number aberrations in young breast cancer patients

scientific article

Negative cell cycle regulator 14-3-3sigma stabilizes p27 Kip1 by inhibiting the activity of PKB/Akt.

scientific article published on 13 March 2006

Obesity-associated NLRC4 inflammasome activation drives breast cancer progression

scientific article published on 06 October 2016

Phase I trial of exemestane in combination with metformin and rosiglitazone in nondiabetic obese postmenopausal women with hormone receptor-positive metastatic breast cancer

scientific article published on 28 September 2012

Pim-1 plays a pivotal role in hypoxia-induced chemoresistance.

scientific article

Regulating the stability and localization of CDK inhibitor p27(Kip1) via CSN6-COP1 axis

scientific article

Regulation of the p53-MDM2 pathway by 14-3-3 sigma and other proteins.

scientific article

Roles for CSN5 in control of p53/MDM2 activities.

scientific article

Roles for negative cell regulator 14-3-3σ in control of MDM2 activities

scientific article published on 04 June 2007

Roles of COP9 signalosome in cancer ⬇️

scientific article published on September 15, 2011

TRIM24 links glucose metabolism with transformation of human mammary epithelial cells

scientific article

The association of diabetes and anti-diabetic medications with clinical outcomes in multiple myeloma

scientific article

The brain-specific activator p35 allows Cdk5 to escape inhibition by p27Kip1 in neurons.

scientific article published on April 1996

Thiazolidinediones and metformin associated with improved survival of diabetic prostate cancer patients ⬇️

scientific article published on March 17, 2011

Transcriptional activation of the Cdk inhibitor p21 by vitamin D3 leads to the induced differentiation of the myelomonocytic cell line U937.

scientific article published on January 1996

Tumor suppressor ARF inhibits HER-2/neu-mediated oncogenic growth

scientific article

p53 negatively regulates Aurora A via both transcriptional and posttranslational regulation

scientific article

Paulina is supported by:

About Paulina

Help