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List of works by Luca Mazzarella

A knowledge-based framework for the discovery of cancer-predisposing variants using large-scale sequencing breast cancer data

scientific article

A new approach to assess drug sensitivity in cells for novel drug discovery.

scientific article published on 7 February 2018

Are we ready for routine precision medicine? Highlights from the Milan Summit on Precision Medicine, Milan, Italy, 8-9 February 2018.

scientific article

Cetuximab for treating non-small cell lung cancer.

scientific article published on 14 March 2018

Clinical efficacy of ribociclib as a first-line therapy for HR-positive, advanced breast cancer.

scientific article

Combination of Hypoglycemia and Metformin Impairs Tumor Metabolic Plasticity and Growth by Modulating the PP2A-GSK3β-MCL-1 Axis

scientific article published on 25 April 2019

Cytotoxic drugs for patients with breast cancer in the era of targeted treatment: back to the future? ⬇️

scientific article published on 06 September 2011

Cytotoxic effect of (1-methyl-1H-imidazol-2-yl)-methanamine and its derivatives in Pt(II) complexes on human carcinoma cell lines: a comparative study with cisplatin.

scientific article published on 5 February 2013

DOTS-Finder: a comprehensive tool for assessing driver genes in cancer genomes.

scientific article

Embryonic stem cell-derived hemangioblasts remain epigenetically plastic and require PRC1 to prevent neural gene expression.

scientific article published on 28 September 2010

Entinostat for the treatment of breast cancer.

scientific article published on 18 July 2017

Epigenetic priming of a pre-B cell-specific enhancer through binding of Sox2 and Foxd3 at the ESC stage.

scientific article

Genetic alterations in hepatoblastoma and hepatocellular carcinoma associated with familial adenomatous polyposis

scientific article published on 01 November 2003

High rate of stem cell mobilization failure after thalidomide and oral cyclophosphamide induction therapy for multiple myeloma.

scientific article published on 21 June 2010

Highlights from the 58th meeting of the American Society of Haematology, 1-6 December 2016, San Diego, USA.

scientific article published on 09 March 2017

Increased BMI correlates with higher risk of disease relapse and differentiation syndrome in patients with acute promyelocytic leukemia treated with the AIDA protocols

scientific article published on 02 November 2011

Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage differentiation and recruitment of PRC1 and RNA Polymerase II to developmental regulators.

scientific article published on 16 May 2010

Liver toxicity in the era of immune checkpoint inhibitors: A practical approach

scientific article published on 03 October 2018

Maintenance of leukemic cell identity by the activity of the Polycomb complex PRC1 in mice.

scientific article published on 7 October 2016

Master protocols in immuno-oncology: do novel drugs deserve novel designs?

scientific article published on 01 March 2020

Obesity increases the incidence of distant metastases in oestrogen receptor-negative human epidermal growth factor receptor 2-positive breast cancer patients.

scientific article

Obesity is a risk factor for acute promyelocytic leukemia: evidence from population and cross-sectional studies studies and correlation with flt3 mutations and polyunsaturated fatty acid metabolism

scientific article published on 12 September 2019

Orlando Magic: report from the 57th meeting of the American Society of Haematology, 5-7 December 2015, Orlando, USA.

scientific article published on 14 January 2016

Rise of the mutants: report from the 19th conference of the European Haematology Association, Milan, 12-15 June 2014

scientific article published on 18 August 2014

Runx proteins regulate Foxp3 expression

scientific article published on 19 October 2009

Semantic and geographical analysis of Covid-19 trials reveals a fragmented clinical research landscape likely to impair informativeness.

scientific article published on 19 May 2020

Tales from the Jazz ASH: highlights from the 2013 American Society of Haematology meeting.

scientific article published on 24 January 2014

The evolving landscape of 'next-generation' immune checkpoint inhibitors: A review

scientific article published on 21 June 2019

The genomic and epigenomic landscapes of AML.

scientific article published on 26 August 2014

Tumor mutational burden quantification from targeted gene panels: major advancements and challenges

scientific article published on 15 July 2019

Tumour-derived PGD2 and NKp30-B7H6 engagement drives an immunosuppressive ILC2-MDSC axis

scientific article published on 19 September 2017

Why does obesity promote cancer? Epidemiology, biology, and open questions

scientific article

p53 Loss in Breast Cancer Leads to Myc Activation, Increased Cell Plasticity, and Expression of a Mitotic Signature with Prognostic Value

scientific article published on 01 January 2019

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