List of works - Kenichi Shimada

Cell-Line Selectivity Improves the Predictive Power of Pharmacogenomic Analyses and Helps Identify NADPH as Biomarker for Ferroptosis Sensitivity

scientific article published on 3 February 2016

Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway

scientific article

Design and synthesis of Pictet–Spengler condensation products that exhibit oncogenic-RAS synthetic lethality and induce non-apoptotic cell death ⬇️

scientific article published on June 30, 2012

Development of small-molecule probes that selectively kill cells induced to express mutant RAS

scientific article

Discovery of Mdm2-MdmX E3 ligase inhibitors using a cell-based ubiquitination assay.

scientific article published on 28 July 2011

Ferrostatins inhibit oxidative lipid damage and cell death in diverse disease models

scientific article

Global survey of cell death mechanisms reveals metabolic regulation of ferroptosis.

scientific article published on 09 May 2016

Human Pluripotency Is Initiated and Preserved by a Unique Subset of Founder Cells

scientific article published on 11 April 2019

Identification of Simple Compounds with Microtubule-Binding Activity That Inhibit Cancer Cell Growth with High Potency

scientific article published on 31 October 2011

Modulatory profiling identifies mechanisms of small molecule-induced cell death.

scientific article

Regulation of ferroptotic cancer cell death by GPX4

scientific article

Transdermal delivery of a readthrough-inducing drug: a new approach of gentamicin administration for the treatment of nonsense mutation-mediated disorders.

scientific article published on 11 November 2009

Unraveling the mechanism of cell death induced by chemical fibrils

scientific article

Unsupervised identification of disease states from high-dimensional physiological and histopathological profiles

scientific article published on 19 February 2019

shinyDepMap, a tool to identify targetable cancer genes and their functional connections from Cancer Dependency Map data

scientific article published on 08 February 2021

tRNA synthase suppression activates de novo cysteine synthesis to compensate for cystine and glutathione deprivation during ferroptosis

scientific article published on 06 October 2015

List of works by Kenichi Shimada

Cell-Line Selectivity Improves the Predictive Power of Pharmacogenomic Analyses and Helps Identify NADPH as Biomarker for Ferroptosis Sensitivity

Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway

Design and synthesis of Pictet–Spengler condensation products that exhibit oncogenic-RAS synthetic lethality and induce non-apoptotic cell death ⬇️

Development of small-molecule probes that selectively kill cells induced to express mutant RAS

Discovery of Mdm2-MdmX E3 ligase inhibitors using a cell-based ubiquitination assay.

Ferrostatins inhibit oxidative lipid damage and cell death in diverse disease models

Global survey of cell death mechanisms reveals metabolic regulation of ferroptosis.

Human Pluripotency Is Initiated and Preserved by a Unique Subset of Founder Cells

Identification of Simple Compounds with Microtubule-Binding Activity That Inhibit Cancer Cell Growth with High Potency

Modulatory profiling identifies mechanisms of small molecule-induced cell death.

Regulation of ferroptotic cancer cell death by GPX4

Transdermal delivery of a readthrough-inducing drug: a new approach of gentamicin administration for the treatment of nonsense mutation-mediated disorders.

Unraveling the mechanism of cell death induced by chemical fibrils

Unsupervised identification of disease states from high-dimensional physiological and histopathological profiles

shinyDepMap, a tool to identify targetable cancer genes and their functional connections from Cancer Dependency Map data

tRNA synthase suppression activates de novo cysteine synthesis to compensate for cystine and glutathione deprivation during ferroptosis