Search filters

List of works by Pierre-Antoine Bonnet

Analytical method for the identification and assay of 12 phthalates in cosmetic products: application of the ISO 12787 international standard "Cosmetics-Analytical methods-Validation criteria for analytical results using chromatographic techniques"

scientific article published on 04 July 2012

Antiproliferative effects of imidazo[1,2-a]pyrazine derivatives on the Dami cell line.

scientific article published on August 1997

Cardiovascular effects of SCA40, a novel potassium channel opener, in rats.

scientific article published on November 1993

Challenging near infrared spectroscopy discriminating ability for counterfeit pharmaceuticals detection.

scientific article published on 12 November 2009

Characterization of a new anticancer agent, EAPB0203, and its main metabolites: nuclear magnetic resonance and liquid chromatography-mass spectrometry studies

scientific article published on 31 October 2012

Detection of hazardous weight-loss substances in adulterated slimming formulations using ultra-high-pressure liquid chromatography with diode-array detection.

scientific article published on 9 December 2011

Determination of 19 antiretroviral agents in pharmaceuticals or suspected products with two methods using high-performance liquid chromatography

scientific article published on 27 December 2006

Dissociation between phosphodiesterase inhibition and antiproliferative effects of phosphodiesterase inhibitors on the Dami cell line.

scientific article published on April 1997

EAPB0203, a member of the imidazoquinoxaline family, inhibits growth and induces caspase-dependent apoptosis in T-cell lymphomas and HTLV-I-associated adult T-cell leukemia/lymphoma

scientific article

EAPB0503, a novel imidazoquinoxaline derivative, inhibits growth and induces apoptosis in chronic myeloid leukemia cells

scientific article published on July 2014

EAPB0503: An Imiquimod analog with potent in vitro activity against cutaneous leishmaniasis caused by Leishmania major and Leishmania tropica

scientific article published on 21 November 2018

Effects of SCA40 on bovine trachealis muscle and on cyclic nucleotide phosphodiesterases.

scientific article published in September 1997

Evaluation of the relaxant effects of SCA40, a novel charybdotoxin‐sensitive potassium channel opener, in guinea‐pig isolated trachealis

scientific article published on March 1, 1993

Fluorescence Study of Imidazoquinoxalines

scientific article published on 03 May 2017

HMOX1 and NQO1 genes are upregulated in response to contact sensitizers in dendritic cells and THP-1 cell line: role of the Keap1/Nrf2 pathway.

scientific article

Identification and quantification of 14 phthalates and 5 non-phthalate plasticizers in PVC medical devices by GC-MS

scientific article published on 02 January 2014

Imidazo[1,2-]quinoxalines Derivatives Grafted with Amino Acids: Synthesis and Evaluation on A375 Melanoma Cells

Imidazo[1,2-a]pyrazine, Imidazo[1,5-a]quinoxaline and Pyrazolo[1,5-a]quinoxaline derivatives as IKK1 and IKK2 inhibitors.

scientific article published on 19 July 2017

Imidazoquinoxaline derivative EAPB0503: A promising drug targeting mutant nucleophosmin 1 in acute myeloid leukemia

scientific article published on 5 January 2017

In vitro and in vivo anti-tumoral activities of imidazo[1,2-a]quinoxaline, imidazo[1,5-a]quinoxaline, and pyrazolo[1,5-a]quinoxaline derivatives.

scientific article

Isolation and structure elucidation of a highly haemolytic saponin from the Merck saponin extract using high-field gradient-enhanced NMR techniques

scientific article published on 01 July 1997

Lipid nanocapsules formulation and cellular activities evaluation of a promising anticancer agent: EAPB0503.

scientific article published in October 2017

Liquid chromatography-electrospray ionization-tandem mass spectrometry method for quantitative estimation of new imiqualine leads with potent anticancer activities in rat and mouse plasma. Application to a pharmacokinetic study in mice

scientific article published on 24 October 2017

Metabolism and pharmacokinetics of EAPB0203 and EAPB0503, two imidazoquinoxaline compounds previously shown to have antitumoral activity on melanoma and T-lymphomas.

scientific article published on 21 July 2010

Modulation of leukocyte genetic expression by novel purine nucleoside analogues. A new approach to antitumor and antiviral agents.

scientific article

New IKK inhibitors: Synthesis of new imidazo[1,2-a]quinoxaline derivatives using microwave assistance and biological evaluation as IKK inhibitors.

scientific article

New imidazoquinoxaline derivatives: Synthesis, biological evaluation on melanoma, effect on tubulin polymerization and structure-activity relationships.

scientific article published on April 2016

Novel and Selective TLR7 Antagonists among the Imidazo[1,2-a]pyrazines, Imidazo[1,5-a]quinoxalines, and Pyrazolo[1,5-a]quinoxalines Series

scientific article published on 19 July 2019

Pharmacokinetic study of gadolinium-DOTA in control and streptozocin diabetic rats

scientific article published on 01 November 1992

Pharmacokinetic study of tempo carboxylic acid, a nitroxyl MRI contrast media, in control and streptozocin diabetic rats

scientific article published on 01 August 1989

Qualitative and quantitative evaluation of a local lymph node assay based on ex vivo interleukin-2 production.

scientific article published in January 2005

Quantitation of imidazo[1,2-a]quinoxaline derivatives in human and rat plasma using LC/ESI-MS.

scientific article published in May 2009

Raman chemical imaging for spectroscopic screening and direct quantification of falsified drugs

scientific article published on 19 October 2017

Relaxivity enhancement of low molecular weight nitroxide stable free radicals: importance of structure and medium.

scientific article published on July 1994

Structural characterization of in vitro metabolites of the new anticancer agent EAPB0503 by liquid chromatography-tandem mass spectrometry

scientific article

Synthesis and antibronchospastic activity of 8-alkoxy- and 8-(alkylamino)imidazo[1,2-a]pyrazines

scientific article published on September 4, 1992

The cytokine-dependent MUTZ-3 cell line as an in vitro model for the screening of contact sensitizers.

scientific article