Search filters

List of works by Stefano Biffo

A Mad2-Mediated Translational Regulatory Mechanism Promoting S-Phase Cyclin Synthesis Controls Origin Firing and Survival to Replication Stress.

scientific article published in May 2018

A Polysome-Based microRNA Screen Identifies miR-24-3p as a Novel Promigratory miRNA in Mesothelioma

scientific article published on 02 August 2018

Bulbectomy Enhances Neurogenesis and Cell Turnover of Primary Olfactory Neurons But Does Not Abolish Carnosine Expression

scientific article published on 01 January 1992

Cap dependent translation contributes to resistance of myeloma cells to bortezomib

scientific article published on 18 November 2013

Cellular localization of carnosine-like and anserine-like immunoreactivities in rodent and avian central nervous system

scientific article published on 01 January 1990

Crosstalks between translation and metabolism in cancer

scientific article published on 15 November 2017

Cytoskeletal proteins associate with components of the ribosomal maturation and translation apparatus in Xenopus stage I oocytes

scientific article published on 17 September 2014

Data on the effects of eIF6 downmodulation on the proportions of innate and adaptive immune system cell subpopulations and on thymocyte maturation

scientific article published on 30 August 2017

Deregulation of the PI3K and KRAS signaling pathways in human cancer cells determines their response to everolimus

scientific article

Development and migration of olfactory neurones in the nervous system of the neonatal opossum.

scientific article published in October 1995

Direct and high throughput (HT) interactions on the ribosomal surface by iRIA.

scientific article published on 21 October 2015

Distribution and characterization of neuropeptide Y-like immunoreactivity in the brain of the crested newt

scientific article published on 01 September 1988

Distribution of carnosine-like immunoreactivity in the brain of the crested newt.

scientific article

Double labeling with non-isotopic in situ hybridization and BrdU immunohistochemistry: calmodulin (CaM) mRNA expression in post-mitotic neurons of the olfactory system

scientific article published on April 1, 1992

Epigallocatechin-3-gallate induces mesothelioma cell death via H2 O2 -dependent T-type Ca2+ channel opening.

scientific article

Eukaryotic initiation factor 6 is rate-limiting in translation, growth and transformation

scientific article published on 10 September 2008

Eukaryotic initiation factor 6 mediates a continuum between 60S ribosome biogenesis and translation

scientific article published on 17 April 2009

Eukaryotic initiation factor eIF6 modulates the expression of Kermit 2/XGIPC in IGF- regulated eye development.

scientific article published on May 2017

Eukaryotic ribosomes host PKC activity

scientific article published on September 2008

Eukaryotic translation initiation factor 6 is a novel regulator of reactive oxygen species-dependent megakaryocyte maturation

scientific journal article

Expression and activity of eIF6 trigger malignant pleural mesothelioma growth in vivo.

scientific article published on 6 October 2015

Expression of a highly conserved protein, p27BBP, during the progression of human colorectal cancer

scientific article published on 01 February 2000

FAM46C and FNDC3A are multiple myeloma tumor suppressors that act in concert to impair clearing of protein aggregates and autophagy

scientific article published on 22 September 2020

Ferroportin is a monomer in vivo in mice

scientific article published on 27 December 2005

Fibronectin controls cap-dependent translation through beta1 integrin and eukaryotic initiation factors 4 and 2 coordinated pathways

scientific article

Formation of nuclear matrix filaments by p27(BBP)/eIF6.

scientific article published in July 2002

GABP complex regulates transcription of eIF6 (p27BBP), an essential trans-acting factor in ribosome biogenesis

scientific article published on 06 March 2006

Growth defects and impaired cognitive-behavioral abilities in mice with knockout for Eif4h, a gene located in the mouse homolog of the Williams-Beuren syndrome critical region

scientific journal article

High levels of eukaryotic Initiation Factor 6 (eIF6) are required for immune system homeostasis and for steering the glycolytic flux of TCR-stimulated CD4+ T cells in both mice and humans

scientific article

Immunocytochemical localization of protein p27BBP in human skin and invertebrate (Sepia officinalis) integument

scientific article published on 18 May 2005

Impairment of cytoplasmic eIF6 activity restricts lymphomagenesis and tumor progression without affecting normal growth

scientific article

In situ hybridization: optimization of the techniques for collecting and fixing the specimens.

scientific article published on August 1992

Isolation of a novel beta4 integrin-binding protein (p27(BBP)) highly expressed in epithelial cells

scientific journal article

JNK inhibition arrests cotranslational degradation

scientific article published on 30 March 2010

Long non-coding antisense RNA controls Uchl1 translation through an embedded SINEB2 repeat.

scientific article

MicroRNA Inhibition of Translation Initiation in Vitro by Targeting the Cap-Binding Complex eIF4F

scientific article published in Science

Molecular control of neuronal survival in the chick embryo.

scientific article published on January 1994

Nuclear myosin VI enhances RNA polymerase II-dependent transcription

scientific article published in September 2006

Overexpression of p27BBP in head and neck carcinomas and their lymph node metastases

scientific article

PKCbetaII modulates translation independently from mTOR and through RACK1.

scientific article published in October 2008

Phosphorylation of p27(BBP)/eIF6 and its association with the cytoskeleton are developmentally regulated in Xenopus oogenesis.

scientific article published in July 2005

Preclinical demonstration of synergistic Active Nutrients/Drug (AND) combination as a potential treatment for malignant pleural mesothelioma

scientific article

RACK1 Specifically Regulates Translation through Its Binding to Ribosomes

scientific article published on 13 November 2018

RACK1 depletion in a mouse model causes lethality, pigmentation deficits and reduction in protein synthesis efficiency

scientific journal article

Reduced AKT/mTOR signaling and protein synthesis dysregulation in a Rett syndrome animal model.

scientific article published on 6 January 2011

Regulation of gene expression in the olfactory neuroepithelium: a neurogenetic matrix.

scientific article published on January 1991

Release of eIF6 (p27BBP) from the 60S subunit allows 80S ribosome assembly

scientific article (publication date: 4 December 2003)

Role of microRNAs in translation regulation and cancer.

scientific article published on February 2017

SBDS-Deficient Cells Have an Altered Homeostatic Equilibrium due to Translational Inefficiency Which Explains their Reduced Fitness and Provides a Logical Framework for Intervention.

scientific article

Selective ascorbate toxicity in malignant mesothelioma: a redox Trojan mechanism

scientific article

Selective binding and internalisation by truncated receptors restrict the availability of BDNF during development.

scientific article

Sen34p depletion blocks tRNA splicing in vivo and delays rRNA processing

scientific article

Sensitivity of global translation to mTOR inhibition in REN cells depends on the equilibrium between eIF4E and 4E-BP1.

scientific article

Spreading of mesothelioma cells is rapamycin-sensitive and requires continuing translation.

scientific article

Tagging of functional ribosomes in living cells by HaloTag® technology.

scientific article

The Role of Eif6 in Skeletal Muscle Homeostasis Revealed by Endurance Training Co-expression Networks ⬇️

scientific article published in November 2017

The Translational Machinery of Human CD4+ T Cells Is Poised for Activation and Controls the Switch from Quiescence to Metabolic Remodeling

scientific article published on 01 December 2018

The Translational Machinery of Human CD4+ T Cells Is Poised for Activation and Controls the Switch from Quiescence to Metabolic Remodeling

scientific article published on 06 September 2018

The beta4 integrin interactor p27(BBP/eIF6) is an essential nuclear matrix protein involved in 60S ribosomal subunit assembly

scientific article

The human ITGB4BP gene is constitutively expressed in vitro, but highly modulated in vivo

scientific article (publication date: 21 March 2001)

The ribonuclease DIS3 promotes let-7 miRNA maturation by degrading the pluripotency factor LIN28B mRNA.

scientific article published on 29 April 2015

The use of radioactively labelled riboprobes for in situ hybridizaiotn; background and examples of applicaiton ⬇️

scientific article published on August 1, 1992

Translating the Game: Ribosomes as Active Players

scientific article published on 15 November 2018

Translation factors and ribosomal proteins control tumor onset and progression: how?

scientific article published on 06 May 2013

Translational control by 80S formation and 60S availability: the central role of eIF6, a rate limiting factor in cell cycle progression and tumorigenesis.

scientific article published on 15 October 2011

Translational control by mTOR-independent routes: how eIF6 organizes metabolism

scientific article published on December 2016

eIF6

eIF6 anti-association activity is required for ribosome biogenesis, translational control and tumor progression

scientific article published on 22 September 2014

eIF6 coordinates insulin sensitivity and lipid metabolism by coupling translation to transcription

scientific journal article

mTORC1-mediated inhibition of polycystin-1 expression drives renal cyst formation in tuberous sclerosis complex

scientific article published on 2 March 2016

p27(BBP)/eIF6 acts as an anti-apoptotic factor upstream of Bcl-2 during Xenopus laevis development.

scientific article published on 25 September 2009

Paulina is supported by:

About Paulina

Help