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List of works by Margit Mahlapuu

A forkhead gene, FoxE3, is essential for lens epithelial proliferation and closure of the lens vesicle

scientific article

A lactoferrin-derived peptide (PXL01) for the reduction of adhesion formation in flexor tendon surgery: an experimental study in rabbits

scientific article published on 23 June 2011

A novel polypeptide derived from human lactoferrin in sodium hyaluronate prevents postsurgical adhesion formation in the rat

scientific article published on 01 December 2009

AMP-activated protein kinase inhibits IL-6-stimulated inflammatory response in human liver cells by suppressing phosphorylation of signal transducer and activator of transcription 3 (STAT3).

scientific article published on 24 July 2010

Administration of Lactobacillus evokes coordinated changes in the intestinal expression profile of genes regulating energy homeostasis and immune phenotype in mice

scientific article published on 16 April 2007

Anti-infectious and anti-inflammatory effects of peptide fragments sequentially derived from the antimicrobial peptide centrocin 1 isolated from the green sea urchin, Strongylocentrotus droebachiensis.

scientific article published on 13 December 2012

Anti-infective efficacy of the lactoferrin-derived antimicrobial peptide HLR1r.

scientific article published on 4 May 2016

Antimicrobial Peptides: An Emerging Category of Therapeutic Agents

scientific article published on 27 December 2016

Antimicrobial synergy of monolaurin lipid nanocapsules with adsorbed antimicrobial peptides against Staphylococcus aureus biofilms in vitro is absent in vivo

scientific article published on 19 November 2018

Characterization of the in vitro, ex vivo, and in vivo Efficacy of the Antimicrobial Peptide DPK-060 Used for Topical Treatment.

scientific article published on 28 May 2019

Cubosomes for topical delivery of the antimicrobial peptide LL-37

scientific article published on 13 November 2018

Differential activation of lung-specific genes by two forkhead proteins, FREAC-1 and FREAC-2

scientific article

Effect of lactoferrin peptide (PXL01) on rabbit digit mobility after flexor tendon repair.

scientific article

Effects of calcineurin activation on insulin-, AICAR- and contraction-induced glucose transport in skeletal muscle

scientific article published on 23 June 2005

Efficacy and safety profile of the novel antimicrobial peptide PXL150 in a mouse model of infected burn wounds

scientific article published on 16 January 2015

Erratum to "Anti-infective efficacy of the lactoferrin-derived antimicrobial peptide HLR1r" [Peptides vol. 81 (2016) 21-28].

scientific article published on 31 August 2016

Expression profiling of the gamma-subunit isoforms of AMP-activated protein kinase suggests a major role for gamma3 in white skeletal muscle

scientific article

FREAC-1 contains a cell-type-specific transcriptional activation domain and is expressed in epithelial-mesenchymal interfaces

scientific article

Fibroblast growth factor 21 signaling: The liver in focus

scientific article published on 18 May 2016

Forkhead transcription factors: key players in development and metabolism

scientific article (publication date: October 2002)

Genetic Disruption of Protein Kinase STK25 Ameliorates Metabolic Defects in a Diet-Induced Type 2 Diabetes Model

scientific article published on 06 April 2015

Increased expression of STK25 leads to impaired glucose utilization and insulin sensitivity in mice challenged with a high-fat diet

scientific article published on 31 May 2013

Lipid droplet-associated kinase STK25 regulates peroxisomal activity and metabolic stress response in steatotic liver

scientific article published on 19 December 2019

Mice lacking melanin-concentrating hormone receptor 1 demonstrate increased heart rate associated with altered autonomic activity

scientific article

Opposite transcriptional regulation in skeletal muscle of AMP-activated protein kinase gamma3 R225Q transgenic versus knock-out mice

scientific article published on 12 January 2006

Overexpression of protein kinase STK25 in mice exacerbates ectopic lipid accumulation, mitochondrial dysfunction and insulin resistance in skeletal muscle.

scientific article published on 16 December 2016

PXL01 in sodium hyaluronate for improvement of hand recovery after flexor tendon repair surgery: randomized controlled trial

scientific article

PXL01 in sodium hyaluronate results in increased PRG4 expression: a potential mechanism for anti-adhesion

scientific article published on 23 September 2016

Partial hepatic resistance to IL-6-induced inflammation develops in type 2 diabetic mice, while the anti-inflammatory effect of AMPK is maintained

scientific article published on 26 June 2014

Pharmacological activation of AMPK suppresses inflammatory response evoked by IL-6 signalling in mouse liver and in human hepatocytes.

scientific article published on 21 May 2013

Protein kinase MST3 modulates lipid homeostasis in hepatocytes and correlates with nonalcoholic steatohepatitis in humans

scientific article published on 07 June 2019

Protein kinase STK25 aggravates the severity of non-alcoholic fatty pancreas disease in mice.

scientific article published on 25 April 2017

Protein kinase STK25 regulates hepatic lipid partitioning and progression of liver steatosis and NASH.

scientific article

Regulation of the muscle-specific AMP-activated protein kinase alpha2beta2gamma3 complexes by AMP and implications of the mutations in the gamma3-subunit for the AMP dependence of the enzyme.

scientific article

Relationship between AMPK and the transcriptional balance of clock-related genes in skeletal muscle

scientific article

Role of AMP-activated protein kinase in the coordinated expression of genes controlling glucose and lipid metabolism in mouse white skeletal muscle

scientific article published on 20 October 2005

STK25 is a critical determinant in nonalcoholic steatohepatitis

scientific article published on 15 July 2016

Serine/threonine protein kinase 25 antisense oligonucleotide treatment reverses glucose intolerance, insulin resistance, and nonalcoholic fatty liver disease in mice.

scientific article published on 20 November 2017

Targeted Delivery of Stk25 Antisense Oligonucleotides to Hepatocytes Protects Mice Against Nonalcoholic Fatty Liver Disease

scientific article published on 19 December 2018

The 5'-AMP-activated protein kinase gamma3 isoform has a key role in carbohydrate and lipid metabolism in glycolytic skeletal muscle

scientific article

The human forkhead protein FREAC-2 contains two functionally redundant activation domains and interacts with TBP and TFIIB

scientific article

The novel antimicrobial peptide PXL150 in the local treatment of skin and soft tissue infections

scientific article published on 4 October 2012

The two-exon gene of the human forkhead transcription factor FREAC-2 (FKHL6) is located at 6p25.3.

scientific article