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List of works by Richard Schulz

Activation and modulation of 72kDa matrix metalloproteinase-2 by peroxynitrite and glutathione

scientific article

Activation of MMP-2 as a key event in oxidative stress injury to the heart

Activation of intracellular matrix metalloproteinase-2 by reactive oxygen-nitrogen species: Consequences and therapeutic strategies in the heart

scientific article published on 05 October 2013

Acute actions and novel targets of matrix metalloproteinases in the heart and vasculature

scientific article

Analysis of Myocardial Plasmalogen and Diacyl Phospholipids and Their Arachidonic Acid Content Using High-Performance Liquid Chromatography

scientific article published on 01 August 1993

Antioxidant treatment protects diabetic rats from cardiac dysfunction by preserving contractile protein targets of oxidative stress

scientific article published on 01 December 2009

Calcium extrusion by plasma membrane calcium pump is impaired in caveolin-1 knockout mouse small intestine

scientific article

Calpain inhibitors exhibit matrix metalloproteinase-2 inhibitory activity

scientific article published on 7 May 2012

Cardiac function is not significantly diminished in hearts isolated from young caveolin-1 knockout mice

scientific article

Cardiomyocyte overexpression of iNOS in mice results in peroxynitrite generation, heart block, and sudden death

article

Caveolin-1 exists and may function in cardiomyocytes

scientific article

Caveolin-1 inhibits matrix metalloproteinase-2 activity in the heart

scientific journal article

Caveolin-1 knockout alters beta-adrenoceptors function in mouse small intestine

scientific journal article

Characterization of 5'AMP-activated protein kinase activity in the heart and its role in inhibiting acetyl-CoA carboxylase during reperfusion following ischemia

scientific article

Degradation of myosin light chain in isolated rat hearts subjected to ischemia-reperfusion injury: a new intracellular target for matrix metalloproteinase-2.

scientific article published on 18 July 2005

Detection of specific nitrotyrosine-modified proteins as a marker of oxidative stress in cardiovascular disease

scientific article published on 17 February 2006

Development and mechanism of a specific supersensitivity to nitrovasodilators after inhibition of vascular nitric oxide synthesis in vivo.

scientific article published on March 1991

Differential inhibitory control of circular and longitudinal smooth muscle layers of Balb/C mouse small intestine

scientific article published on 17 July 2006

Doxycycline Attenuates Renal Injury In A Swine Model Of Neonatal Hypoxia-Reoxygenation

Doxycycline reduces cardiac matrix metalloproteinase-2 activity but does not ameliorate myocardial dysfunction during reperfusion in coronary artery bypass patients undergoing cardiopulmonary bypass.

scientific article published in November 2013

Effects of Vasospasm on Levels of Prostacyclin and Thromboxane A2 in Cerebral Arteries of the Monkey

Endothelial dependence of matrix metalloproteinase-mediated vascular hyporeactivity caused by lipopolysaccharide

scientific article

Enhanced NO and superoxide generation in dysfunctional hearts from endotoxemic rats

scientific article published in September 2002

Generation of peroxynitrite contributes to ischemia-reperfusion injury in isolated rat hearts

scientific article published on 01 February 1997

Glutathione Protects Against Myocardial Ischemia–reperfusion Injury by Detoxifying Peroxynitrite

Glycogen synthase kinase-3beta is activated by matrix metalloproteinase-2 mediated proteolysis in cardiomyoblasts

scientific article

Human pancreatic islet beta-cell destruction by cytokines is independent of nitric oxide production

scientific article published on 01 October 1994

Hydrogen peroxide causes cardiac dysfunction independent from its effects on matrix metalloproteinase-2 activationThis paper is one of a selection of papers published in this Special Issue, entitled The Cellular and Molecular Basis of Cardiovascular

article

Hydrogen peroxide-induced necrotic cell death in cardiomyocytes is independent of matrix metalloproteinase-2.

scientific article published on 7 May 2013

Hyperlipidemia attenuates the infarct size-limiting effect of ischemic preconditioning: role of matrix metalloproteinase-2 inhibition

scientific article published on 15 September 2005

Imbalance between tissue inhibitor of metalloproteinase-4 and matrix metalloproteinases during acute myocardial [correction of myoctardial] ischemia-reperfusion injury

scientific journal article

Impact of caveolin-1 knockout on NANC relaxation in circular muscles of the mouse small intestine compared with longitudinal muscles

scientific article published on 15 September 2005

Increased activities of cardiac matrix metalloproteinases matrix metalloproteinase (MMP)-2 and MMP-9 are associated with mortality during the acute phase of experimental Trypanosoma cruzi infection.

scientific article

Influence of beta-adrenoceptor tone on the cardioprotective efficacy of adenosine A(1) receptor activation in isolated working rat hearts

scientific article published in October 2000

Inhaled nitric oxide and inhibition of platelet aggregation in critically ill neonates

scientific article published in The Lancet

Inhibiting matrix metalloproteinase-2 reduces protein release into coronary effluent from isolated rat hearts during ischemia-reperfusion

scientific article published on 28 May 2008

Inhibition of endogenous nitric oxide in the heart enhances matrix metalloproteinase-2 release

scientific article published in May 2005

Inhibition of inducible nitric oxide synthase and superoxide production reduces matrix metalloproteinase-9 activity and restores coronary vasomotor function in rat cardiac allografts

scientific article

Inhibition of matrix metalloproteinase activity in vivo protects against vascular hyporeactivity in endotoxemia

scientific article

Inhibition of matrix metalloproteinase-2 by PARP inhibitors

scientific article published on 18 July 2009

Inhibition of matrix metalloproteinases prevents peroxynitrite-induced contractile dysfunction in the isolated cardiac myocyte.

scientific article published on 10 December 2007

Inhibition of nitric oxide synthesis protects the isolated working rabbit heart from ischaemia-reperfusion injury

scientific article published on 01 September 1995

Inhibitory effects of caspase inhibitors on the activity of matrix metalloproteinase-2 ⬇️

scientific article published on June 14, 2013

Intracellular Action of Matrix Metalloproteinase-2 Accounts for Acute Myocardial Ischemia and Reperfusion Injury

scientific article published on 01 September 2002

Intracellular MMP-2: Role in Normal and Diseased Hearts

article published in 2011

Intracellular targets of matrix metalloproteinase-2 in cardiac disease: rationale and therapeutic approaches

scientific article published on January 2007

Ischemia/reperfusion-induced myosin light chain 1 phosphorylation increases its degradation by matrix metalloproteinase 2.

scientific article

Isolated heart perfusion according to Langendorff---still viable in the new millennium

scientific article published on 26 May 2006

Junctophilin-2 is a target of matrix metalloproteinase-2 in myocardial ischemia-reperfusion injury

scientific article published on 10 September 2019

K(ATP)-channel activation: effects on myocardial recovery from ischaemia and role in the cardioprotective response to adenosine A1-receptor stimulation

scientific article

MMP-2 and MMP-9 and their tissue inhibitors in the plasma of preterm and term neonates

scientific article published on 18 February 2004

MMP-2 is localized to the mitochondria-associated membrane of the heart

scientific article published on 27 December 2013

Matrix metalloproteinase activities are altered in the heart and plasma during endotoxemia

scientific article published in June 2004

Matrix metalloproteinase inhibition attenuates right ventricular dysfunction and improves responses to dobutamine during acute pulmonary thromboembolism.

scientific article

Matrix metalloproteinase inhibitor properties of tetracyclines: therapeutic potential in cardiovascular diseases

scientific article published on 31 May 2011

Matrix metalloproteinase inhibitors attenuate endotoxemia induced cardiac dysfunction: a potential role for MMP-9

scientific article published on 01 September 2003

Matrix metalloproteinase-2 (MMP-2) is present in the nucleus of cardiac myocytes and is capable of cleaving poly (ADP-ribose) polymerase (PARP) in vitro

scientific article published on 06 February 2004

Matrix metalloproteinase-2 and myocardial oxidative stress injury: beyond the matrix

scientific article published on 04 August 2009

Matrix metalloproteinase-2 degrades the cytoskeletal protein α-actinin in peroxynitrite mediated myocardial injury

scientific article published on 31 July 2007

Matrix metalloproteinase-2 proteolysis of calponin-1 contributes to vascular hypocontractility in endotoxemic rats

scientific article

Matrix metalloproteinase-2, caveolins, focal adhesion kinase and c-Kit in cells of the mouse myocardium

scientific article

Matrix metalloproteinase-2: an emerging biomarker for reperfusion injury following percutaneous coronary intervention

scientific article published on 13 September 2011

Matrix metalloproteinase-7 and ADAM-12 (a disintegrin and metalloproteinase-12) define a signaling axis in agonist-induced hypertension and cardiac hypertrophy.

scientific article published on 27 April 2009

Matrix metalloproteinases 2 and 9 as diagnostic markers in the progression to Chagas cardiomyopathy

scientific article published on 15 February 2013

Matrix metalloproteinases 2 and 9 as diagnostic tools in Chagas cardiomyopathy

Matrix metalloproteinases contribute to endotoxin and interleukin-1beta induced vascular dysfunction

scientific journal article

Mechanisms of arachidonic acid-induced contractions of canine cerebral arteries

scientific article published on 01 April 1987

Mechanisms of cytokine-induced destruction of rat insulinoma cells: the role of nitric oxide.

scientific article published on March 1994

Mechanisms of cytosolic targeting of matrix metalloproteinase-2.

scientific article

Mmp25β facilitates elongation of sensory neurons during zebrafish development

scientific article published on 6 August 2014

Multifunctional Intracellular Matrix Metalloproteinases: Implications in Disease

scientific article published on 06 January 2021

Myocardial MMP-2 contributes to SERCA2a proteolysis during cardiac ischaemia-reperfusion injury

scientific article published on 01 April 2020

Myocardial matrix metalloproteinase-2: inside out and upside down.

scientific article

Nitrate tolerance does not increase production of peroxynitrite in the heart

scientific article

Nitric oxide, superoxide, and peroxynitrite in myocardial ischaemia-reperfusion injury and preconditioning

scientific article

Nitrosative stress and pharmacological modulation of heart failure

scientific article

PPARα: essential component to prevent myocardial oxidative stress?

scientific article published on 23 March 2007

Peroxynitrite inactivates human-tissue inhibitor of metalloproteinase-4.

scientific article

Phosphorylation status of 72 kDa MMP-2 determines its structure and activity in response to peroxynitrite.

scientific article

Phosphorylation status of matrix metalloproteinase 2 in myocardial ischaemia-reperfusion injury

scientific article published on 7 March 2012

Physiological levels of amyloid peptides stimulate the angiogenic response through FGF-2

scientific article published on 24 September 2004

Poly(ADP-Ribose) polymerase inhibition reduces reperfusion injury after heart transplantation

scientific article published in January 2002

Post-resuscitation NOS inhibition does not improve hemodynamic recovery of hypoxic newborn pigs.

scientific article published on 24 June 2009

Postresuscitation administration of doxycycline preserves cardiac contractile function in hypoxia-reoxygenation injury of newborn piglets*.

scientific article published in April 2014

Predictive Value of Matrix Metalloproteinases and Their Inhibitors for Mortality in Septic Patients: A Cohort Study

scientific article published in January 2017

Production of 15-HETE by Cultured Smooth Muscle Cells from Cerebral Artery

scientific article published on 01 April 1993

Prognostic Value of MMP-9 -1562 C/T Gene Polymorphism in Patients With Sepsis.

scientific article published on 20 May 2019

Protective action of doxycycline against diabetic cardiomyopathy in rats

scientific article published on 22 September 2008

Proteomics analysis of changes in myocardial proteins during endotoxemia

scientific article

Pyruvate prevents cardiac dysfunction and AMP-activated protein kinase activation by hydrogen peroxide in isolated rat hearts

scientific article published in June 2004

Rapid increase in inducible nitric oxide synthase gene expression in the heart during endotoxemia.

scientific article published in May 1996

Regulation of matrix metalloproteinase-2 (MMP-2) activity by phosphorylation

scientific article published on 13 April 2007

Release of leukotrienes into the perfusate of calcium-ionophore stimulated rabbit lungs

scientific article published on 01 January 1986

Remodeling of aorta extracellular matrix as a result of transient high oxygen exposure in newborn rats: implication for arterial rigidity and hypertension risk

scientific article

Response of Fetal Rabbit Ductus Arteriosus to Bradykinin: Role of Nitric Oxide, Prostaglandins, and Bradykinin Receptors

article

Role of NO in vascular smooth muscle and cardiac muscle function

scientific article published on 01 July 1994

Role of oxidative stress in multiparity-induced endothelial dysfunction

scientific article published on 29 August 2008

Smooth muscle NOS, colocalized with caveolin-1, modulates contraction in mouse small intestine

scientific article

Smoothelin-B is not a target of matrix metalloproteinase (MMP)-2 in the vasculature of endotoxemic rats.

scientific article published on October 2014

Targeting MMP-2 to treat ischemic heart injury

scientific article published on 02 July 2014

The Alberta Heart Failure Etiology and Analysis Research Team (HEART) study

scientific article

The hemodynamic effects of inhaled nitric oxide and endogenous nitric oxide synthesis blockade in newborn piglets during infusion of heat-killed group B streptococci.

scientific article

The involvement of superoxide and iNOS-derived NO in cardiac dysfunction induced by pro-inflammatory cytokines

scientific article published on 19 September 2005

The l-Arginine

Thiols Protect the Inhibition of Myocardial Aconitase by Peroxynitrite

scientific article published in 1998

Titin is a target of matrix metalloproteinase-2: implications in myocardial ischemia/reperfusion injury

scientific article published on November 2010

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