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List of works by Mitchell G Lawrence

A bioengineered microenvironment to quantitatively measure the tumorigenic properties of cancer-associated fibroblasts in human prostate cancer.

scientific article published on 2 April 2013

A community-based model of rapid autopsy in end-stage cancer patients

scientific article published on 12 September 2016

A single nucleotide polymorphism genotyping platform for the authentication of patient derived xenografts

scientific article published on 09 August 2016

A variant of the KLK4 gene is expressed as a cis sense-antisense chimeric transcript in prostate cancer cells

scientific article published on 20 April 2010

Critical evaluation of the Illumina MethylationEPIC BeadChip microarray for whole-genome DNA methylation profiling.

scientific article published on 07 October 2016

DNA hypermethylation in prostate cancer is a consequence of aberrant epithelial differentiation and hyperproliferation.

scientific article published on 24 January 2014

Direct progesterone receptor and indirect androgen receptor interactions with the kallikrein-related peptidase 4 gene promoter in breast and prostate cancer

scientific article published in January 2009

Epithelial--mesenchymal and mesenchymal--epithelial transitions in carcinoma progression.

scientific article published on November 2007

Epithelial-mesenchymal transition in prostate cancer and the potential role of kallikrein serine proteases

scientific article published on January 2007

Establishment of primary patient-derived xenografts of palliative TURP specimens to study castrate-resistant prostate cancer.

scientific article published on 14 July 2015

Estrogen Receptor β Activation Impairs Prostatic Regeneration by Inducing Apoptosis in Murine and Human Stem/Progenitor Enriched Cell Populations ⬇️

scientific article published on July 10, 2012

Estrogen receptor alpha drives proliferation in PTEN-deficient prostate carcinoma by stimulating survival signaling, MYC expression and altering glucose sensitivity

scientific article

Germline BRCA2 mutations drive prostate cancers with distinct evolutionary trajectories.

scientific article published on 09 January 2017

Intraductal carcinoma of the prostate can evade androgen deprivation, with emergence of castrate-tolerant cells

scientific article published on 4 October 2017

Kallikrein-related peptidase 4 induces cancer-associated fibroblast features in prostate-derived stromal cells

scientific article

Kallikreins on steroids: structure, function, and hormonal regulation of prostate-specific antigen and the extended kallikrein locus

scientific article published on 26 January 2010

Knowing what's growing: Why ductal and intraductal prostate cancer matter

scientific article published on 01 March 2020

Long terminal repeats act as androgen-responsive enhancers for the PSA-kallikrein locus

scientific article published on 17 May 2012

PDX: Moving Beyond Drug Screening to Versatile Models for Research Discovery

scientific article published on 12 September 2020

Patient-derived xenografts reveal that intraductal carcinoma of the prostate is a prominent pathology in BRCA2 mutation carriers with prostate cancer and correlates with poor prognosis.

scientific article published on 22 August 2014

Practical Polling for Prostate Cancer: AR-V7-based Treatment Selection.

scientific article published on 11 January 2017

Primary culture and propagation of human prostate epithelial cells.

scientific article

Reactivation of embryonic nodal signaling is associated with tumor progression and promotes the growth of prostate cancer cells

scientific article

Systematic Review Links the Prevalence of Intraductal Carcinoma of the Prostate to Prostate Cancer Risk Categories

scientific article published on 22 March 2017

The MURAL collection of prostate cancer patient-derived xenografts enables discovery through preclinical models of uro-oncology

scientific article published on 19 August 2021

The kallikrein 14 gene is down-regulated by androgen receptor signalling and harbours genetic variation that is associated with prostate tumour aggressiveness

scientific article

The role of kallikrein-related peptidases in prostate cancer: potential involvement in an epithelial to mesenchymal transition

scientific article published on June 2006

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