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List of works by Francesco Frassoni

A novel Bim-BH3-derived Bcl-XL inhibitor: biochemical characterization, in vitro, in vivo and ex-vivo anti-leukemic activity

scientific article published on 20 October 2008

A novel assay to detect calreticulin mutations in myeloproliferative neoplasms.

scientific article published on 23 December 2016

A revised day +7 predictive score for transplant-related mortality: serum cholinesterase, total protein, blood urea nitrogen, gamma glutamyl transferase, donor type and cell dose.

scientific article published in July 2003

A survey of fully haploidentical hematopoietic stem cell transplantation in adults with high-risk acute leukemia: a risk factor analysis of outcomes for patients in remission at transplantation

scientific article published on 07 July 2008

Aberrant activation of ROS1 represents a new molecular defect in chronic myelomonocytic leukemia

scientific article

Abnormalities of Na/K ATPase in Migraine With Aura

scientific article published on 01 February 2007

Achieving a major molecular response at the time of a complete cytogenetic response (CCgR) predicts a better duration of CCgR in imatinib-treated chronic myeloid leukemia patients.

scientific article

Acute myelogenous leukemia with translocation t(8;21): a cytogenetic study of seven cases

scientific article published on 01 February 1986

Acyclovir for the treatment of severe aplastic anemia

scientific article published on 01 June 1984

Adoptive immunotherapy mediated by ex vivo expanded natural killer T cells against CD1d-expressing lymphoid neoplasms

scientific article published on 19 May 2009

Adult advanced chronic lymphocytic leukemia: computational analysis of whole-body CT documents a bone structure alteration.

scientific article published on 5 March 2014

Allogeneic and autologous transplantation for haematological diseases, solid tumours and immune disorders: definitions and current practice in Europe

scientific article published on 01 April 2002

Allogeneic cell transplant expands bone marrow distribution by colonizing previously abandoned areas: an FDG PET/CT analysis.

scientific article published on 8 May 2015

Allogeneic hemopoietic stem cell transplants for patients with relapsed acute leukemia: long-term outcome

scientific article published on 05 February 2007

Anti-T-cell globulin: an essential ingredient for haematopoietic cell transplantation?

scientific article published on 18 August 2009

Antileukemia effects of xanthohumol in Bcr/Abl-transformed cells involve nuclear factor-kappaB and p53 modulation

scientific article

Autografting with Ph-negative progenitors in patients at diagnosis of chronic myeloid leukemia induces a prolonged prevalence of Ph-negative hemopoiesis

scientific article published on 01 February 2000

Bone marrow transplantation for chronic myeloid leukemia (CML) from unrelated and sibling donors: single center experience ⬇️

scientific article published on December 1, 1997

CMV infection after transplant from cord blood compared to other alternative donors: the importance of donor-negative CMV serostatus

scientific article published on 27 May 2011

Clinical problems associated with T cell depletion for bone marrow transplantation

scientific article published on 01 January 1987

Clinical scale ex vivo expansion of cord blood-derived outgrowth endothelial progenitor cells is associated with high incidence of karyotype aberrations

scientific article published on 21 December 2007

Clonal haematopoiesis is not prevalent in survivors of childhood cancer.

scientific article published on 3 April 2017

Coexistence of normal and clonal haemopoiesis in aplastic anaemia patients treated with immunosuppressive therapy

scientific article published on 01 December 1999

Competition between recipient and donor cells after bone marrow transplantation for chronic myeloid leukaemia

scientific article published on 01 August 1988

Competitive survival/proliferation of normal and Ph1-positive haemopoietic cells

scientific article published on 01 May 1986

Contact with the bone marrow microenvironment readdresses the fate of transplanted hematopoietic stem cells

scientific article published on 13 June 2010

Cord blood transplantation provides better reconstitution of hematopoietic reservoir compared with bone marrow transplantation

scientific article published on 10 April 2003

Cytogenetic follow-up after bone marrow transplantation for Philadelphia-positive chronic myeloid leukemia

scientific article published on 01 October 1989

Deficient reconstitution of early progenitors after allogeneic bone marrow transplantation

scientific article published on 01 May 1997

Design and application of a novel PNA probe for the detection at single cell level of JAK2V617F mutation in Myeloproliferative Neoplasms.

scientific article

Diabetes impairs the vascular recruitment of normal stem cells by oxidant damage, reversed by increases in pAMPK, heme oxygenase-1, and adiponectin

scientific article published on February 2009

Diagnostic and clinical relevance of the number of circulating CD34+ cells in myelofibrosis with myeloid metaplasia

Differential effects of the type of iron chelator on the absolute number of hematopoietic peripheral progenitors in patients with -thalassemia major ⬇️

scientific article published on December 14, 2012

Donor lymphocyte infusions for the treatment of minimal residual disease in acute leukemia

scientific article published on 01 June 2007

Donor multipotent mesenchymal stromal cells may engraft in pediatric patients given either cord blood or bone marrow transplantation

scientific article published on 01 July 2006

Donor-recipient incompatibility at CD31-codon 563 is a major risk factor for acute graft-versus-host disease after allogeneic bone marrow transplantation from a human leucocyte antigen-matched donor

scientific article published on 01 September 2001

Dose-effect relationship for cataract induction after single-dose total body irradiation and bone marrow transplantation for acute leukemia.

scientific article published in April 2002

Effect of centre on outcome of bone-marrow transplantation for acute myeloid leukaemia. Acute Leukaemia Working Party of the European Group for Blood and Marrow Transplantation

scientific article published on 01 April 2000

Effective mobilization of Philadelphia-chromosome-negative cells in chronic myelogenous leukaemia patients using a less intensive regimen

scientific article published on 01 February 1998

Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants

scientific article (publication date: 15 March 2002)

Efficient long-term maintenance of chronic myeloid leukemic cobblestone area forming cells on a murine stromal cell line.

scientific article published on January 1997

Endothelial colony-forming cells from patients with chronic myeloproliferative disorders lack the disease-specific molecular clonality marker

scientific article published on 23 July 2009

EphA3 targeting reduces in vitro adhesion and invasion and in vivo growth and angiogenesis of multiple myeloma cells.

scientific article published on 18 July 2017

Eradication of leukaemic marrow and prevention of leukaemia relapse with total body irradiation and bone marrow transplantation ⬇️

scientific article published on 01 January 1991

Estimating the whole bone-marrow asset in humans by a computational approach to integrated PET/CT imaging.

scientific article published on 26 May 2012

Evidence of cytogenetic and molecular remission by allogeneic cells after immunosuppressive therapy alone

scientific article published on 01 November 1998

Exosomes from human mesenchymal stem cells conduct aerobic metabolism in term and preterm newborn infants

scientific article published on 11 December 2015

Factors influencing haematological recovery after allogeneic haemopoietic stem cell transplants: graft-versus-host disease, donor type, cytomegalovirus infections and cell dose.

scientific article

Factors influencing outcome and incidence of long-term complications in children who underwent autologous stem cell transplantation for acute myeloid leukemia in first complete remission

scientific article published on 10 October 2002

Factors predicting response and graft-versus-host disease after donor lymphocyte infusions: a study on 593 infusions.

scientific article published in April 2003

Feasibility and recent improvement of autologous stem cell transplantation for acute myelocytic leukaemia in patients over 60 years of age: importance of the source of stem cells

article

Foreword. New frontiers in molecular and cellular therapy

scientific article published on 01 September 2013

Fractionated total body irradiation in marrow transplantation for leukaemia

scientific article published on 01 November 1983

Freshly dissociated fetal neural stem/progenitor cells do not turn into blood

scientific article published in February 2003

GM-CFC growth in chronic granulocytic leukaemia is not affected by a soluble inhibitor released by aplastic anaemia T-cells or mitogen-primed normal T-lymphocytes

scientific article published on 01 April 1982

Generation of CFU-C suppressor T cells in vitro. V. A multistep process

scientific article published on 01 November 1982

Generation of CFU-c suppressor T cells. VI. Effect of cyclosporin A

scientific article published on 01 January 1983

Graft-versus-host disease and outcome in HLA-identical sibling transplantations for chronic myeloid leukemia.

scientific article published in December 2002

Graft-versus-leukemia effect following allogeneic bone marrow transplantation.

scientific article

HLA-identical sibling allogeneic peripheral blood stem cell transplantation with reduced intensity conditioning compared to autologous peripheral blood stem cell transplantation for elderly patients with de novo acute myeloid leukemia.

scientific article

Haemopoietic colony formation (BFU-E, GM-CFC) during the development of pure red cell hypoplasia induced in the cat by feline leukaemia virus ⬇️

scientific article published on January 1, 1983

Helical tomotherapy targeting total bone marrow after total body irradiation for patients with relapsed acute leukemia undergoing an allogeneic stem cell transplant.

scientific article published on 19 February 2011

Hematopoietic stem cell transplantation for de novo acute megakaryocytic leukemia in first complete remission: a retrospective study of the European Group for Blood and Marrow Transplantation (EBMT)

scientific article published on 10 June 2004

Hematopoietic stem cell transplantation for hematological malignancies in Europe.

scientific article published in May 2003

High dose bolus methylprednisolone for the treatment of acute graft versus host disease

scientific article published on 01 March 1983

High frequency of endothelial colony forming cells marks a non-active myeloproliferative neoplasm with high risk of splanchnic vein thrombosis

scientific article

Human mesenchymal stem cells and cyclosporin a exert a synergistic suppressive effect on in vitro activation of alloantigen-specific cytotoxic lymphocytes.

scientific article

Human mesenchymal stem cells inhibit antibody production induced in vitro by allostimulation

scientific article published on 19 November 2007

Human mesenchymal stem cells promote survival of T cells in a quiescent state

scientific article published on 29 March 2007

Human serum-dependent survival of GM-CFCs in vitro from patients with chronic granulocytic leukemia

scientific article published on 01 January 1987

Idarubicin alone or in combination with cytarabine and etoposide (3 + 3 + 5 protocol) in acute non-lymphoblastic leukaemia

scientific article published on 01 January 1985

Idarubicin, intermediate-dose cytarabine, etoposide, and granulocyte-colony-stimulating factor are able to recruit CD34+/HLA-DR- cells during early hematopoietic recovery in accelerated and chronic phases of chronic myeloid leukemia

scientific article published on 01 January 1994

Identical outcome after autologous or allogeneic genoidentical hematopoietic stem-cell transplantation in first remission of acute myelocytic leukemia carrying inversion 16 or t(8;21): a retrospective study from the European Cooperative Group for Bl

scientific article published on 27 May 2008

Impact of length of cryopreservation and origin of cord blood units on hematologic recovery following cord blood transplantation

scientific article published on 23 March 2015

Improved outcome in young adults with de novo acute myeloid leukemia in first remission, undergoing an allogeneic bone marrow transplant

scientific article published on 25 June 2007

Improving the outcome of umbilical cord blood transplantation through ex vivo expansion or graft manipulation

scientific article published on 14 March 2015

In vitro tests in severe aplastic anaemia (SAA): a prospective study in 46 patients treated with immunosuppression

scientific article published on 01 April 1985

In vivo B-cell depletion with rituximab for alternative donor hemopoietic SCT

scientific article published on 04 April 2011

In vivo mobilization of karyotypically normal peripheral blood progenitor cells in high-risk MDS, secondary or therapy-related acute myelogenous leukaemia

scientific article published on 01 October 1996

Increased risk of leukemia relapse with high dose cyclosporine after allogeneic marrow transplantation for acute leukemia: 10 year follow-up of a randomized study.

scientific article published in November 2001

Induction and survival of binucleated Purkinje neurons by selective damage and aging.

scientific article

Interferon-α protects Philadelphia-negative progenitors from exhaustion in chronic myeloid leukemia patients with cytogenetic response

scientific article published on 01 January 2001

Intra-bone route of administration offers new perspectives for safer transplantation of hematopoietic stem cells

scientific article published on 01 January 2010

Intrabone transplant of cord blood stem cells establishes a local engraftment store: a functional PET/FDG study.

scientific article

Intravenous monoclonal antibody (BT 5/9) for the treatment of acute graft-versus-host disease

scientific article published on 01 January 1985

Is there a graft-versus-leukaemia effect in the absence of graft-versus-host disease in patients undergoing bone marrow transplantation for acute leukaemia?

scientific article published on 01 December 2000

Karyotype evolution of Ph positive chronic myelogenous leukemia patients relapsed in advanced phases of the disease after allogeneic bone marrow transplantation

scientific article published on 01 November 1991

Late complications of allogeneic bone marrow transplantation

scientific article published on 01 January 1991

Long-term results after allogeneic bone marrow transplantation for chronic myelogenous leukemia in chronic phase: a report from the Chronic Leukemia Working Party of the European Group for Blood and Marrow Transplantation

scientific article published on 01 October 1997

Marrow versus peripheral blood for geno-identical allogeneic stem cell transplantation in acute myelocytic leukemia: influence of dose and stem cell source shows better outcome with rich marrow

scientific article published on 26 June 2003

Mepartricin: A New Antifungal Agent for the Treatment of Disseminated Candida Infections in the Immunocompromised Host ⬇️

scientific article published on January 1, 1983

Mesenchymal stem cells ameliorate experimental autoimmune encephalomyelitis inducing T-cell anergy.

scientific article published on 19 May 2005

Mesenchymal stem cells effectively modulate pathogenic immune response in experimental autoimmune encephalomyelitis

scientific article published in March 2007

Mesenchymal stem cells from preterm to term newborns undergo a significant switch from anaerobic glycolysis to the oxidative phosphorylation

scientific article published on 3 October 2017

Mesenchymal stem cells impair in vivo T-cell priming by dendritic cells

scientific article

Mesenchymal stem cells infusion prevents acute cellular rejection in rat kidney transplantation.

scientific article published in May 2010

Mesenchymal stem cells protective effect in adriamycin model of nephropathy.

scientific article published in January 2008

Mesenchymal stromal cells reset the scatter factor system and cytokine network in experimental kidney transplantation

scientific article

Mesenchymal stromal cells, from indifferent spectators to principal actors. Are we going to witness a revolution in the scenario of allograft and immune-mediated disorders?

scientific article published on 01 July 2007

MiRNAs and piRNAs from bone marrow mesenchymal stem cell extracellular vesicles induce cell survival and inhibit cell differentiation of cord blood hematopoietic stem cells: a new insight in transplantation

scientific article published on 29 December 2015

Mobilization and transplantation of Philadelphia-negative peripheral-blood progenitor cells early in chronic myelogenous leukemia

scientific article published on 01 April 1997

Mobilization/transplantation of Ph1-negative blood progenitor cells in chronic myelogenous leukaemia.

scientific article published on January 1996

Modified in vitro conditions for cord blood-derived long-term culture-initiating cells.

scientific article published on March 2001

Molecular analysis of Philadelphia-negative myeloproliferative syndromes with i(17q)

scientific article published on 01 December 1989

Multiple infusions of mesenchymal stromal cells induce sustained remission in children with steroid-refractory, grade III-IV acute graft-versus-host disease

scientific article published on 31 August 2013

Multipotent mesenchymal stromal cells from amniotic fluid: solid perspectives for clinical application

scientific article

New possibilities to exploit the potentiality of cord blood cells in the context of transplantation.

scientific article published on 27 September 2013

No impact of high-dose cytarabine on the outcome of patients transplanted for acute myeloblastic leukaemia in first remission. Acute Leukaemia Working Party of the European Group for Blood and Marrow Transplantation (EBMT)

scientific article published on 01 August 2000

Nonhuman primate allogeneic hematopoietic stem cell transplantation by intraosseus vs intravenous injection: Engraftment, donor cell distribution, and mechanistic basis

scientific article published on 22 August 2008

Normal and leukaemic haematopoiesis in bone marrow and peripheral blood of patients with chronic myeloid leukaemia

scientific article published on 01 March 1999

Normal primitive haemopoietic progenitors are more frequent than their leukaemic counterpart in newly diagnosed patients with chronic myeloid leukaemia but rapidly decline with time

scientific article published on 01 March 1999

Patients with acute lymphoblastic leukaemia allografted with a matched unrelated donor may have a lower survival with a peripheral blood stem cell graft compared to bone marrow

scientific article published on 01 January 2003

Phenotypic and functional analysis of the HLA-class I-specific inhibitory receptors of natural killer cells isolated from peripheral blood of patients undergoing bone marrow transplantation from matched unrelated donors

scientific article published on 01 January 2000

Phenotypic and functional heterogeneity of human NK cells developing after umbilical cord blood transplantation: a role for human cytomegalovirus?

scientific article published on 17 November 2011

Philadelphia-chromosome-negative peripheral blood stem cells can be mobilized in the early phase of recovery after a myelosuppressive chemotherapy in Philadelphia-chromosome-positive acute lymphoblastic leukaemia

scientific article published on 01 March 1995

Pre-emptive therapy of acute graft-versus-host disease: a pilot study with antithymocyte globulin (ATG).

scientific article published in December 2001

Prediction of response to imatinib by prospective quantitation of BCR-ABL transcript in late chronic phase chronic myeloid leukemia patients

scientific article published on 10 January 2006

Preterm Cord Blood Contains a Higher Proportion of Immature Hematopoietic Progenitors Compared to Term Samples

scientific article published on 29 September 2015

Progenitor cells trapped in marrow filters can reduce GvHD and transplant mortality

scientific article published on 05 June 2006

Prophylactic antithymocyte globulin reduces the risk of chronic graft-versus-host disease in alternative-donor bone marrow transplants.

scientific article published in January 2002

Randomised studies in acute myeloid leukaemia: the double truth

scientific article published on 01 March 2000

Reassessing autotransplantation for acute myeloid leukaemia in first remission - a matched pair analysis of autologous marrow vs peripheral blood stem cells

scientific article published on 01 June 2004

Recurrence of Ph'-positive leukemia in donor cells after marrow transplantation for chronic granulocytic leukemia

scientific article published on 01 April 1984

Reduced intensity thiotepa-cyclophosphamide conditioning for allogeneic haemopoietic stem cell transplants (HSCT) in patients up to 60 years of age.

scientific article published in June 2000

Relapse after allogeneic BMT for chronic myeloid leukemia (CML) may be sustained by a small number of leukemic 'stem cells': a hypothesis

scientific article published on 01 September 1999

Relapse after allogeneic bone marrow transplantation for acute leukaemia: a survey by the E.B.M.T. of 117 cases

scientific article published on 01 November 1988

Relevance of bone marrow cell dose on allogeneic transplantation outcomes for patients with acute myeloid leukemia in first complete remission: results of a European survey

article

Results of syngeneic hematopoietic stem cell transplantation for acute leukemia: risk factors for outcomes of adults transplanted in first complete remission

scientific article published on 10 May 2008

Risk assessment in adult acute lymphoblastic leukaemia before early haemopoietic stem cell transplantation with a geno-identical donor: an easy clinical prognostic score to identify patients who benefit most from allogeneic haemopoietic stem cell tra

scientific article published on 01 August 2003

Rituximab treatment for Epstein-Barr virus DNAemia after alternative-donor hematopoietic stem cell transplantation.

scientific article published on 13 October 2010

Second allogeneic bone marrow transplantation in acute leukemia: results of a survey by the European Cooperative Group for Blood and Marrow Transplantation

scientific article published on 01 August 2001

Selective effect of feline leukaemia virus on early erythroid precursors.

scientific article published in March 1982

Serum cholinesterase is an early and sensitive marker of graft-versus host-disease (GVHD) and transplant-related mortality (TRM)

scientific article published on 01 December 2001

Sex differences in human lymphocyte Na,K-ATPase as studied by labeled ouabain binding.

scientific article published in February 2007

Splenic irradiation before bone marrow transplantation for chronic myeloid leukemia: update of a prospective randomized study

scientific article published on 01 January 1993

Splenic irradiation before hematopoietic stem cell transplantation for chronic myeloid leukemia: long-term follow-up of a prospective randomized study.

scientific article

Spontaneous exodus of high numbers of normal early progenitor cells (Ph-negative LTC-IC) in the peripheral blood of patients with chronic myeloid leukaemia at the beginning of the disease

scientific article published on 01 April 1997

Stem cells for multiple sclerosis: promises and reality

scientific article published on 01 January 2007

Stem cells in inflammatory demyelinating disorders: a dual role for immunosuppression and neuroprotection

scientific article

Stem-cell mobilization for autografting in chronic myeloid leukemia.

scientific article published on September 1997

Strong antileukemic effect of chronic graft-versus-host disease in allogeneic marrow transplant recipients having acute leukemia treated with methotrexate and cyclosporine. The Acute Leukemia Working Party of the European Group for Blood and Marrow

scientific article published on 01 February 1997

T-cell suppression mediated by mesenchymal stem cells is deficient in patients with severe aplastic anemia

scientific article published on 01 July 2005

T-derived colony-inhibiting activity: partial characterization and mechanism of action

scientific article published on 01 January 1985

The Wilms' tumor (WT1) gene expression correlates with the International Prognostic Scoring System (IPSS) score in patients with myelofibrosis and it is a marker of response to therapy

scientific article

The combined effect of total body irradiation (TBI) and cyclosporin A (CyA) on the risk of relapse in patients with acute myeloid leukaemia undergoing allogeneic bone marrow transplantation

scientific article published on 01 January 2000

The dismal outcome in patients with acute leukaemia who relapse after an autograft is improved if a second autograft or a matched allograft is performed. Acute Leukaemia Working Party of the European Group for Blood and Marrow Transplantation (EBMT)

scientific article published on 01 May 2000

The effect of total body irradiation dose and chronic graft-versus-host disease on leukaemic relapse after allogeneic bone marrow transplantation.

scientific article

The intra-bone marrow injection of cord blood cells extends the possibility of transplantation to the majority of patients with malignant hematopoietic diseases ⬇️

scientific article published on June 1, 2010

The laws covering in vitro fertilization and embryo research in Italy

scientific article published on 22 May 2006

The retroviral transduction of HOXC4 into human CD34(+) cells induces an in vitro expansion of clonogenic and early progenitors.

scientific article

The therapeutic potential of mesenchymal stem cell transplantation as a treatment for multiple sclerosis: consensus report of the International MSCT Study Group

scientific article published on 19 January 2010

The ultrastructural localization of factor VIII-antigen in human platelets, megakaryocytes and endothelial cells utilizing a ferritin-labelled antibody

scientific article published on 01 June 1978

Thiotepa-based reduced intensity conditioning regimen: a 10 year follow up

scientific article published on 01 October 2007

Total body irradiation correlates with chronic graft versus host disease and affects prognosis of patients with acute lymphoblastic leukemia receiving an HLA identical allogeneic bone marrow transplant

scientific article published on 01 February 1999

Total body irradiation in acute myeloid leukemia and chronic myelogenous leukemia: influence of dose and dose-rate on leukemia relapse

scientific article published on 01 September 1989

Transplant-related mortality and long-term graft function are significantly influenced by cell dose in patients undergoing allogeneic marrow transplantation

scientific article published on 01 August 2002

Transplantation of peripheral blood stem cells as compared with bone marrow from HLA-identical siblings in adult patients with acute myeloid leukemia and acute lymphoblastic leukemia

scientific article published on 01 December 2002

Transplants of Umbilical-Cord Blood or Bone Marrow from Unrelated Donors in Adults with Acute Leukemia

article

Treatment with granulocyte colony-stimulating factor after allogeneic bone marrow transplantation for acute leukemia increases the risk of graft-versus-host disease and death: a study from the Acute Leukemia Working Party of the European Group for B

scientific article published on 22 December 2003

Twelve years experience with high-dose therapy and autologous stem cell transplantation for high-risk Hodgkin's disease patients in first remission after MOPP/ABVD chemotherapy

scientific article published on 01 March 1996

Unbalanced X‐chromosome inactivation in haemopoietic cells from normal women ⬇️

scientific article published on September 1, 1998

Unrelated cord blood transplantation: outcomes after single-unit intrabone injection compared with double-unit intravenous injection in patients with hematological malignancies

scientific article published in May 2013

Variant Philadelphia translocations in CML: correlation with fragile sites

scientific article published on 01 March 1988

Which is the most suitable and effective route of administration for mesenchymal stem cell-based immunomodulation therapy in experimental kidney transplantation: endovenous or arterial?

scientific article published in May 2010

p38 MAPK and JNK antagonistically control senescence and cytoplasmic p16INK4A expression in doxorubicin-treated endothelial progenitor cells

scientific article

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