Search filters

List of works by Jerome Irianto

As a Nucleus Enters a Small Pore, Chromatin Stretches and Maintains Integrity, Even with DNA Breaks.

scientific article published on 27 October 2016

Cell mechanics, structure, and function are regulated by the stiffness of the three-dimensional microenvironment.

scientific article published on September 2012

Constricted migration increases DNA damage and independently represses cell cycle

scientific article published on 09 May 2018

Constricted migration modulates stem cell differentiation

scientific article published on 12 June 2019

Coordinated increase of nuclear tension and lamin-A with matrix stiffness outcompetes lamin-B receptor that favors soft tissue phenotypes.

scientific article

DNA Damage Follows Repair Factor Depletion and Portends Genome Variation in Cancer Cells after Pore Migration

scientific article published on 9 December 2016

Depletion of chondrocyte primary cilia reduces the compressive modulus of articular cartilage.

scientific article published on 4 December 2013

Elastic-Fluid Model for DNA Damage and Mutation from Nuclear Fluid Segregation Due to Cell Migration.

scientific article

Filomicelles deliver a chemo-differentiation combination of Paclitaxel and Retinoic Acid that durably represses carcinomas in liver to prolong survival

scientific article published on 16 February 2018

Genome variation across cancers scales with tissue stiffness - an invasion-mutation mechanism and implications for immune cell infiltration.

scientific article published on 27 April 2017

Matrix elasticity regulates lamin-A,C phosphorylation and turnover with feedback to actomyosin.

scientific article

Mechanosensing by the Lamina Protects against Nuclear Rupture, DNA Damage, and Cell-Cycle Arrest

scientific article published on 16 May 2019

Mechanosensing by the nucleus: From pathways to scaling relationships.

scientific article published on 2 January 2017

Mitotic progression following DNA damage enables pattern recognition within micronuclei.

scientific article published on 31 July 2017

Nuclear constriction segregates mobile nuclear proteins away from chromatin

scientific article published on 26 October 2016

Nuclear lamin stiffness is a barrier to 3D migration, but softness can limit survival.

scientific article published on 24 February 2014

Nuclear lamins in cancer

scientific article published on 18 April 2016

Nuclear mechanosensing

scientific article published on 21 December 2018

Nuclear rupture at sites of high curvature compromises retention of DNA repair factors

scientific article published on 31 August 2018

Progerin phosphorylation in interphase is lower and less mechanosensitive than lamin-A,C in iPS-derived mesenchymal stem cells.

scientific article

Quantification of chromatin condensation level by image processing

scientific article published on 5 October 2013

Rescue of DNA damage after constricted migration reveals a mechano-regulated threshold for cell cycle

scientific article published on 25 June 2019

SIRPA-Inhibited, Marrow-Derived Macrophages Engorge, Accumulate, and Differentiate in Antibody-Targeted Regression of Solid Tumors

scientific article published on 29 June 2017

SnapShot: Mechanosensing Matrix

scientific article published on June 2016

The rate of hypo-osmotic challenge influences regulatory volume decrease (RVD) and mechanical properties of articular chondrocytes

scientific article published on 11 November 2014