List of works - Lilian Varga

"Nuts and Bolts" of Laboratory Evaluation of Angioedema

scientific article published on 3 May 2016

A novel assay to diagnose hereditary angioedema utilizing inhibition of bradykinin-forming enzymes

scientific article published on 15 October 2014

A novel assay to quantitate MASP-2/ficolin-3 complexes in serum

scientific article published on 08 November 2012

A novel prophylaxis with C1-inhibitor concentrate in hereditary angioedema during erythema marginatum.

scientific article published on 31 May 2017

A systematic analysis of the complement pathways in patients with neuromyelitis optica indicates alteration but no activation during remission.

scientific article published on 26 October 2013

Acquired angioedema associated with chronic hepatitis C

scientific article published on 01 April 1999

Acquired angioedema associated with primary antiphospholipid syndrome in a patient with antithrombin III deficiency

scientific article published on 18 January 2008

Activation of the ficolin-lectin pathway during attacks of hereditary angioedema

scientific article published on 16 July 2014

Acute abdominal attack of hereditary angioneurotic oedema associated with ultrasound abnormalities suggestive of acute hepatitis

scientific article published on 01 January 2002

Adverse effects of danazol prophylaxis on the lipid profiles of patients with hereditary angioedema.

scientific article

Alternative complement pathway activation during invasive coronary procedures in acute myocardial infarction and stable angina pectoris

scientific article published on 26 October 2016

Anti-cholesterol antibody levels in hereditary angioedema.

scientific article

Antibodies against human heat-shock protein (hsp) 60 and mycobacterial hsp65 differ in their antigen specificity and complement-activating ability

scientific article published on 01 September 1999

Are these patients indeed resistant to treatment with C1 inhibitor concentrate?

scientific article published on 17 October 2011

Assessment of inhibitory antibodies in patients with hereditary angioedema treated with plasma-derived C1 inhibitor.

scientific article published on 24 October 2016

Association between early onset and organ manifestations of systemic lupus erythematosus (SLE) and a down-regulating promoter polymorphism in the MBL2 gene

article

Association of Low Ficolin-Lectin Pathway Parameters with Cardiac Syndrome X.

scientific article published on 17 June 2016

Association of celiac disease and hereditary angioedema due to C1-inhibitor deficiency. Screening patients with hereditary angioedema for celiac disease: is it worth the effort?

scientific article published on 01 March 2011

Association of celiac disease and hereditary angioneurotic edema

scientific article published on 01 October 2002

Association of high serum concentration of the third component of complement (C3) with pre-existing severe coronary artery disease and new vascular events in women

scientific article published on 01 December 2004

Atrial natriuretic peptide as a novel biomarker of hereditary angioedema

scientific article published on 04 March 2016

Bacteriuria increases the risk of edematous attacks in hereditary angioedema with C1-inhibitor deficiency.

scientific article published on 22 August 2016

Baseline level of functional C1-inhibitor correlates with disease severity scores in hereditary angioedema

scientific article published on 27 November 2009

C1 and C4 abnormalities in chronic lymphocytic leukaemia and their significance

scientific article published on 01 February 1987

C1 inhibitor: quantification and purification

scientific article published on 01 January 2014

C1-inhibitor (C1-INH) autoantibodies in hereditary angioedema. Strong correlation with the severity of disease in C1-INH concentrate naïve patients

scientific article published on 05 June 2006

C1-inhibitor autoantibodies in SLE

scientific article published on 13 January 2010

C1r-C1s-C1inhibitor (C1rs-C1inh) complex measurements in tears of patients before and after penetrating keratoplasty

scientific article published on 01 February 2002

Canadian 2003 International Consensus Algorithm For the Diagnosis, Therapy, and Management of Hereditary Angioedema.

scientific article published in September 2004

Clinical management of hereditary angio-oedema in children.

scientific article

Coincidence of hereditary angioedema (HAE) with Crohn's disease

scientific article published on 01 January 1999

Comparative study of the complement-activating and specific IgE-binding properties of ragweed pollen allergen

scientific article published on 01 April 1997

Complement activation in the nasal mucosa following nasal ragweed-allergen challenge

scientific article published on 01 August 2001

Complete kinetic follow-up of symptoms and complement parameters during a hereditary angioedema attack

scientific article published on 7 October 2017

Comprehensive study into the activation of the plasma enzyme systems during attacks of hereditary angioedema due to C1-inhibitor deficiency

scientific article

Danazol therapy for hereditary angio-oedema in children

scientific article published on 01 September 1999

Dancing with Complement C4 and the RP-C4-CYP21-TNX (RCCX) Modules of the Major Histocompatibility Complex ⬇️

scientific article published on January 1, 2003

Decreased inhibition of immune precipitation by sera with the C2 B allotype

scientific article published on 01 April 1991

Deep venous thrombosis associated with acquired angioedema type II in a patient heterozygous for the mutation of factor V Leiden: effective treatment and follow-up for four years

scientific article published on 01 May 2006

Depressed activation of the lectin pathway of complement in hereditary angioedema

Early complement activation follows eversion carotid endarterectomy and correlates with the time of clamping of the carotid artery.

scientific article published on 28 March 2008

Elevated C1rC1sC1inh levels independently predict atherosclerotic coronary heart disease

scientific article published on 20 November 2012

Endothelial cell activation during edematous attacks of hereditary angioedema types I and II

scientific article published on 09 February 2014

Eradication of Helicobacter pylori and improvement of hereditary angioneurotic oedema

scientific article published in November 2001

Erythema marginatum preceding an acute oedematous attack of hereditary angioneurotic oedema

scientific article published on 01 October 2001

Esophageal leiomyoma incidentally recognized during an acute attack of hereditary angioneurotic edema

scientific article published on 01 May 2001

F12-46C/T polymorphism as modifier of the clinical phenotype of hereditary angioedema

scientific article published on 6 August 2015

First report of icatibant treatment in a pregnant patient with hereditary angioedema

scientific article published on 19 April 2016

Frequency of the virilising effects of attenuated androgens reported by women with hereditary angioedema

scientific article

Functional analysis of the mannose-binding lectin complement pathway in normal pregnancy and preeclampsia.

scientific article

Hereditary angiodema: a current state-of-the-art review, VII: Canadian Hungarian 2007 International Consensus Algorithm for the Diagnosis, Therapy, and Management of Hereditary Angioedema.

scientific article published on January 2008

Hereditary angioedema: a decade of human C1-inhibitor concentrate therapy.

scientific article published on 29 August 2007

Hereditary angioedema: molecular and clinical differences among European populations.

scientific article published on 23 September 2014

High levels of acute phase proteins and soluble 70 kDa heat shock proteins are independent and additive risk factors for mortality in colorectal cancer

scientific article

High normal serum levels of C3 and C1 inhibitor, two acute-phase proteins belonging to the complement system, occur more frequently in patients with Crohn's disease than ulcerative colitis.

scientific article published in June 2003

Home treatment of attacks with conestat alfa in hereditary angioedema due to C1-inhibitor deficiency.

scientific article published in May 2014

Home treatment of hereditary angioedema with icatibant administered by health care professionals

scientific article published on 09 December 2011

Idiopathic Nonhistaminergic Acquired Angioedema Versus Hereditary Angioedema

scientific article published on 30 April 2018

Immunological alterations in anti-HTLV-III negative haemophiliacs and homosexual men in Hungary.

scientific article

In vitro complement activation by ragweed allergen extract in the sera of ragweed allergic and non-allergic persons

scientific article published on 01 November 1995

International consensus on the diagnosis and management of pediatric patients with hereditary angioedema with C1 inhibitor deficiency.

scientific article published on 09 August 2016

Lack of increased prevalence of immunoregulatory disorders in hereditary angioedema due to C1-inhibitor deficiency

scientific article published on 19 May 2011

Less severe clinical manifestations in patients with hereditary angioedema with missense C1INH gene mutations

scientific article published on 23 December 2012

Long-term danazol prophylaxis does not lead to increased carotid intima-media thickness in hereditary angioedema patients.

scientific article published on 30 October 2007

Long-term efficacy of danazol treatment in hereditary angioedema.

scientific article published on 18 October 2010

Low C1-Inhibitor Levels Predict Early Restenosis After Eversion Carotid Endarterectomy

scientific article published on 04 October 2007

Management of hereditary angioedema in pediatric patients.

scientific article published on 27 August 2007

Management of pregnancies in a hereditary angioedema patient after treatment with attenuated androgens since childhood

scientific article published on 12 June 2014

Neutrophil activation during attacks in patients with hereditary angioedema due to C1-inhibitor deficiency

scientific article

Novel Vasoregulatory Aspects of Hereditary Angioedema: the Role of Arginine Vasopressin, Adrenomedullin and Endothelin-1.

scientific article published on 12 February 2016

Novel duplication in the F12 gene in a patient with recurrent angioedema

scientific article published on 09 August 2013

Parameters of the classical complement pathway predict disease severity in hereditary angioedema

scientific article published on 20 January 2011

Prophylactic therapy in children with hereditary angioedema.

scientific article published on 24 September 2012

Ragweed allergy: correlation between skin reactivity and in vitro complement activation

scientific article published on 01 December 1998

Recombinant human C1-inhibitor in the treatment of acute angioedema attacks.

scientific article

Relationship between complement components C4A and C4B diversities and two TNFA promoter polymorphisms in two healthy Caucasian populations

scientific article published on 01 May 2003

Relationship between copy number of genes (C4A, C4B) encoding the fourth component of complement and the clinical course of hereditary angioedema (HAE)

article

Reply

scientific article published on 16 March 2017

Risk of thromboembolism in patients with hereditary angioedema treated with plasma-derived C1-inhibitor

scientific article published on 21 January 2016

Role of complement in the pathomechanism of atherosclerotic vascular diseases.

scientific article published on 06 June 2009

Serum anti-cholesterol antibodies in chronic hepatitis-C patients during IFN-alpha-2b treatment.

scientific article published in January 2003

Short-term prophylaxis in a patient with acquired C1-INH deficiency.

scientific article published on 24 April 2014

Short-term prophylaxis in hereditary angioedema due to deficiency of the C1-inhibitor--a long-term survey

Streptokinase does not activate the complement system

scientific article published on 01 October 2000

Strong complement activation after acute ischemic stroke is associated with unfavorable outcomes.

scientific article published on 14 August 2008

Strong correlation of high EBNA-1-IgG levels with edematous attacks involving upper airway mucosa in hereditary angioedema due to C1-inhibitor deficiency

scientific article published on 03 December 2011

Studies on the interactions between C-reactive protein and complement proteins.

scientific article published on 18 January 2007

Studies on the mechanisms of allergen-induced activation of the classical and lectin pathways of complement

scientific article published on 01 May 2003

Successful outcome using C1-inhibitor concentrate in acute pancreatitis caused by hereditary angioedema

scientific article published on 01 January 2011

Successful pregnancy outcome after treatment with C1-inhibitor concentrate in a patient with hereditary angioedema and a history of four miscarriages

scientific article published on 11 August 2012

Successful prophylaxis with recombinant human C1 inhibitor in a patient with hereditary angioedema

scientific article published on 06 November 2014

The Hungarian HAE experience

scientific article published on 01 December 2003

The Levels of the Lectin Pathway Serine Protease MASP-1 and Its Complex Formation with C1 Inhibitor Are Linked to the Severity of Hereditary Angioedema.

scientific article

The effect of long-term danazol treatment on haematological parameters in hereditary angioedema

scientific article published on 25 February 2016

The efficacy of short-term danazol prophylaxis in hereditary angioedema patients undergoing maxillofacial and dental procedures

scientific article published on 01 April 1999

The influence of trigger factors on hereditary angioedema due to C1-inhibitor deficiency

scientific article published on 28 March 2014

The role of complement activation in the pathogenesis of Fuchs' dystrophy.

scientific article

The role of ficolins and MASPs in hereditary angioedema due to C1-inhibitor deficiency

scientific article published on 12 January 2013

The role of the complement system in hereditary angioedema.

scientific article

The severity of clinical symptoms in ragweed-allergic patients is related to the extent of ragweed-induced complement activation in their sera

scientific article published on 01 November 1997

The use of 'real-time' complement analysis to differentiate atypical haemolytic uraemic syndrome from other forms of thrombotic microangiopathies

scientific article published on 22 May 2012

Thyroid hormones and complement parameters in hereditary angioedema with C1-inhibitor deficiency.

scientific article published on 28 June 2016

Treatment of attacks with plasma-derived C1-inhibitor concentrate in pediatric hereditary angioedema patients

scientific article published on 11 October 2012

Treatment with C1-inhibitor concentrate does not induce IgM type anti-C1 inhibitor antibodies in patients with hereditary angioedema ⬇️

scientific article published on December 15, 2010

Ultrasonography in the diagnosis and monitoring of ascites in acute abdominal attacks of hereditary angioneurotic oedema.

scientific article published on October 2001

Usefulness of detection of complement activation products in evaluating SLE activity

scientific article published on 01 January 2000

rhC1INH: a new drug for the treatment of attacks in hereditary angioedema caused by C1-inhibitor deficiency.

scientific article published on March 2011

List of works by Lilian Varga

"Nuts and Bolts" of Laboratory Evaluation of Angioedema

A novel assay to diagnose hereditary angioedema utilizing inhibition of bradykinin-forming enzymes

A novel assay to quantitate MASP-2/ficolin-3 complexes in serum

A novel prophylaxis with C1-inhibitor concentrate in hereditary angioedema during erythema marginatum.

A systematic analysis of the complement pathways in patients with neuromyelitis optica indicates alteration but no activation during remission.

Acquired angioedema associated with chronic hepatitis C

Acquired angioedema associated with primary antiphospholipid syndrome in a patient with antithrombin III deficiency

Activation of the ficolin-lectin pathway during attacks of hereditary angioedema

Acute abdominal attack of hereditary angioneurotic oedema associated with ultrasound abnormalities suggestive of acute hepatitis

Adverse effects of danazol prophylaxis on the lipid profiles of patients with hereditary angioedema.

Alternative complement pathway activation during invasive coronary procedures in acute myocardial infarction and stable angina pectoris

Anti-cholesterol antibody levels in hereditary angioedema.

Antibodies against human heat-shock protein (hsp) 60 and mycobacterial hsp65 differ in their antigen specificity and complement-activating ability

Are these patients indeed resistant to treatment with C1 inhibitor concentrate?

Assessment of inhibitory antibodies in patients with hereditary angioedema treated with plasma-derived C1 inhibitor.

Association between early onset and organ manifestations of systemic lupus erythematosus (SLE) and a down-regulating promoter polymorphism in the MBL2 gene

Association of Low Ficolin-Lectin Pathway Parameters with Cardiac Syndrome X.

Association of celiac disease and hereditary angioedema due to C1-inhibitor deficiency. Screening patients with hereditary angioedema for celiac disease: is it worth the effort?

Association of celiac disease and hereditary angioneurotic edema

Association of high serum concentration of the third component of complement (C3) with pre-existing severe coronary artery disease and new vascular events in women

Atrial natriuretic peptide as a novel biomarker of hereditary angioedema

Bacteriuria increases the risk of edematous attacks in hereditary angioedema with C1-inhibitor deficiency.

Baseline level of functional C1-inhibitor correlates with disease severity scores in hereditary angioedema

C1 and C4 abnormalities in chronic lymphocytic leukaemia and their significance

C1 inhibitor: quantification and purification

C1-inhibitor (C1-INH) autoantibodies in hereditary angioedema. Strong correlation with the severity of disease in C1-INH concentrate naïve patients

C1-inhibitor autoantibodies in SLE

C1r-C1s-C1inhibitor (C1rs-C1inh) complex measurements in tears of patients before and after penetrating keratoplasty

Canadian 2003 International Consensus Algorithm For the Diagnosis, Therapy, and Management of Hereditary Angioedema.

Clinical management of hereditary angio-oedema in children.

Coincidence of hereditary angioedema (HAE) with Crohn's disease

Comparative study of the complement-activating and specific IgE-binding properties of ragweed pollen allergen

Complement activation in the nasal mucosa following nasal ragweed-allergen challenge

Complete kinetic follow-up of symptoms and complement parameters during a hereditary angioedema attack

Comprehensive study into the activation of the plasma enzyme systems during attacks of hereditary angioedema due to C1-inhibitor deficiency

Danazol therapy for hereditary angio-oedema in children

Dancing with Complement C4 and the RP-C4-CYP21-TNX (RCCX) Modules of the Major Histocompatibility Complex ⬇️

Decreased inhibition of immune precipitation by sera with the C2 B allotype

Deep venous thrombosis associated with acquired angioedema type II in a patient heterozygous for the mutation of factor V Leiden: effective treatment and follow-up for four years

Depressed activation of the lectin pathway of complement in hereditary angioedema

Early complement activation follows eversion carotid endarterectomy and correlates with the time of clamping of the carotid artery.

Elevated C1rC1sC1inh levels independently predict atherosclerotic coronary heart disease

Endothelial cell activation during edematous attacks of hereditary angioedema types I and II

Eradication of Helicobacter pylori and improvement of hereditary angioneurotic oedema

Erythema marginatum preceding an acute oedematous attack of hereditary angioneurotic oedema

Esophageal leiomyoma incidentally recognized during an acute attack of hereditary angioneurotic edema

F12-46C/T polymorphism as modifier of the clinical phenotype of hereditary angioedema

First report of icatibant treatment in a pregnant patient with hereditary angioedema

Frequency of the virilising effects of attenuated androgens reported by women with hereditary angioedema

Functional analysis of the mannose-binding lectin complement pathway in normal pregnancy and preeclampsia.

Hereditary angiodema: a current state-of-the-art review, VII: Canadian Hungarian 2007 International Consensus Algorithm for the Diagnosis, Therapy, and Management of Hereditary Angioedema.

Hereditary angioedema: a decade of human C1-inhibitor concentrate therapy.

Hereditary angioedema: molecular and clinical differences among European populations.

High levels of acute phase proteins and soluble 70 kDa heat shock proteins are independent and additive risk factors for mortality in colorectal cancer

High normal serum levels of C3 and C1 inhibitor, two acute-phase proteins belonging to the complement system, occur more frequently in patients with Crohn's disease than ulcerative colitis.

Home treatment of attacks with conestat alfa in hereditary angioedema due to C1-inhibitor deficiency.

Home treatment of hereditary angioedema with icatibant administered by health care professionals

Idiopathic Nonhistaminergic Acquired Angioedema Versus Hereditary Angioedema

Immunological alterations in anti-HTLV-III negative haemophiliacs and homosexual men in Hungary.

In vitro complement activation by ragweed allergen extract in the sera of ragweed allergic and non-allergic persons

International consensus on the diagnosis and management of pediatric patients with hereditary angioedema with C1 inhibitor deficiency.

Lack of increased prevalence of immunoregulatory disorders in hereditary angioedema due to C1-inhibitor deficiency

Less severe clinical manifestations in patients with hereditary angioedema with missense C1INH gene mutations

Long-term danazol prophylaxis does not lead to increased carotid intima-media thickness in hereditary angioedema patients.

Long-term efficacy of danazol treatment in hereditary angioedema.

Low C1-Inhibitor Levels Predict Early Restenosis After Eversion Carotid Endarterectomy

Management of hereditary angioedema in pediatric patients.

Management of pregnancies in a hereditary angioedema patient after treatment with attenuated androgens since childhood

Neutrophil activation during attacks in patients with hereditary angioedema due to C1-inhibitor deficiency

Novel Vasoregulatory Aspects of Hereditary Angioedema: the Role of Arginine Vasopressin, Adrenomedullin and Endothelin-1.

Novel duplication in the F12 gene in a patient with recurrent angioedema

Parameters of the classical complement pathway predict disease severity in hereditary angioedema

Prophylactic therapy in children with hereditary angioedema.

Ragweed allergy: correlation between skin reactivity and in vitro complement activation

Recombinant human C1-inhibitor in the treatment of acute angioedema attacks.

Relationship between complement components C4A and C4B diversities and two TNFA promoter polymorphisms in two healthy Caucasian populations

Relationship between copy number of genes (C4A, C4B) encoding the fourth component of complement and the clinical course of hereditary angioedema (HAE)

Reply

Risk of thromboembolism in patients with hereditary angioedema treated with plasma-derived C1-inhibitor