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List of works by Marco Ladetto

13q14 deletion size and number of deleted cells both influence prognosis in chronic lymphocytic leukemia

scientific article published on 11 May 2011

A B-cell receptor-related gene signature predicts response to ibrutinib treatment in mantle cell lymphoma cell lines

scientific article published on 28 February 2019

A B-cell receptor-related gene signature predicts survival in mantle cell lymphoma: results from the Fondazione Italiana Linfomi MCL-0208 trial.

scientific article published on 22 February 2018

A Single-Center Pilot Prospective Study of Topical Application of Platelet-Derived Eye Drops for Patients with Ocular Chronic Graft-versus-Host Disease

scientific article published on 3 June 2016

A novel nested-PCR strategy for the detection of rearranged immunoglobulin heavy-chain genes in B cell tumors

scientific article published on 01 October 1997

A validated real-time quantitative PCR approach shows a correlation between tumor burden and successful ex vivo purging in follicular lymphoma patients.

scientific article

AT7519, A novel small molecule multi-cyclin-dependent kinase inhibitor, induces apoptosis in multiple myeloma via GSK-3beta activation and RNA polymerase II inhibition.

scientific article published on 25 January 2010

Addition of Rituximab to Involved-Field Radiation Therapy Prolongs Progression-free Survival in Stage I-II Follicular Lymphoma: Results of a Multicenter Study.

scientific article published on 17 December 2015

Antiviral treatment in patients with indolent B-cell lymphomas associated with HCV infection: a study of the Fondazione Italiana Linfomi.

scientific article published on 5 May 2014

Autologous stem cell transplantation with in vivo purged progenitor cells shows long-term efficacy in relapsed/refractory follicular lymphoma.

scientific article published on March 2015

BRAF gene is not mutated in plasma cell leukemia and multiple myeloma

scientific article published on 01 November 2003

CD49d expression is an independent risk factor of progressive disease in early stage chronic lymphocytic leukemia.

scientific article

Cells carrying nonlymphoma-associated bcl-2/IgH rearrangements (NLABR) are phenotypically related to follicular lymphoma and can establish as long-term persisting clonal populations.

scientific article

Clinical and molecular remission after allogeneic blood cell transplantation in a patient with mantle-cell lymphoma

scientific article published on 01 August 1996

Combinatorial targeting of nuclear export and translation of RNA inhibits aggressive B-cell lymphomas

scientific article published on 24 November 2015

Comparative assessment of telomere length before and after hematopoietic SCT: role of grafted cells in determining post-transplant telomere status

scientific article published on 19 October 2009

Comparison of different DNA extraction methods from peripheral blood cells: advice from the Fondazione Italiana Linfomi Minimal Residual Disease Network

scientific article published on 11 March 2015

Comparison of two real-time quantitative polymerase chain reaction strategies for minimal residual disease evaluation in lymphoproliferative disorders: correlation between immunoglobulin gene mutation load and real-time quantitative polymerase chain

scientific article published on 19 November 2013

Concurrent administration of high-dose chemotherapy and rituximab is a feasible and effective chemo/immunotherapy for patients with high-risk non-Hodgkin's lymphoma

scientific article published on 01 December 2001

Cyclooxygenase-2 (COX-2) is frequently expressed in multiple myeloma and is an independent predictor of poor outcome.

scientific article

Data quality improvement of a multicenter clinical trial dataset

scientific article published in July 2017

Del(13q14.3) length matters: an integrated analysis of genomic, fluorescence in situ hybridization and clinical data in 169 chronic lymphocytic leukaemia patients with 13q deletion alone or a normal karyotype

scientific article published on 13 June 2011

Diffuse large B-cell lymphoma (DLBCL): ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.

scientific article published in September 2015

Dysfunctional Vγ9Vδ2 T cells are negative prognosticators and markers of dysregulated mevalonate pathway activity in chronic lymphocytic leukemia cells.

scientific article published on 29 August 2012

ESMO Consensus conferences: guidelines on malignant lymphoma. part 2: marginal zone lymphoma, mantle cell lymphoma, peripheral T-cell lymphoma.

scientific article published on 20 February 2013

ESMO consensus conference on malignant lymphoma: general perspectives and recommendations for prognostic tools in mature B-cell lymphomas and chronic lymphocytic leukaemia

scientific article published on 01 February 2018

Epigenomic evolution in diffuse large B-cell lymphomas

scientific article published on 20 April 2015

Extranodal diffuse large B-cell lymphoma (DLBCL) and primary mediastinal B-cell lymphoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

scientific article published on 04 July 2016

Ficoll-hypaque separation vs whole blood lysis: Comparison of efficiency and impact on minimal residual disease analysis

scientific article published on 4 December 2017

Gastric marginal zone lymphoma of MALT type: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

scientific article published on 01 October 2013

Genome-wide DNA profiling better defines the prognosis of chronic lymphocytic leukaemia.

scientific article published on 12 July 2011

HashClone: a new tool to quantify the minimal residual disease in B-cell lymphoma from deep sequencing data

scientific article published on 23 November 2017

High XBP1 expression is a marker of better outcome in multiple myeloma patients treated with bortezomib

scientific article published on February 2014

High-risk fludarabine-pretreated B-cell chronic lymphocytic leukemia's high response rate following sequential DHAP and alemtuzumab administration though in absence of molecular remission

scientific article published on 01 January 2006

IGHV unmutated CLL B cells are more prone to spontaneous apoptosis and subject to environmental prosurvival signals than mutated CLL B cells

scientific article published on 04 March 2011

Immunoglobulin framework-derived peptides function as cytotoxic T-cell epitopes commonly expressed in B-cell malignancies

article

Infections and Follicular Lymphoma: is there a Link?

scientific article

Inter- and intratumoral heterogeneity of BCL2 correlates with IgH expression and prognosis in follicular lymphoma.

scientific article

Interim 18-FDG-PET/CT failed to predict the outcome in diffuse large B-cell lymphoma patients treated at the diagnosis with rituximab-CHOP.

scientific article published on 10 January 2012

Khorana score and histotype predicts incidence of early venous thromboembolism in non-Hodgkin lymphomas

scientific article published on 27 April 2017

Lenalidomide plus R-CHOP21 in elderly patients with untreated diffuse large B-cell lymphoma: results of the REAL07 open-label, multicentre, phase 2 trial

scientific article

Lenalidomide plus cyclophosphamide, doxorubicin, vincristine, prednisone and rituximab is safe and effective in untreated, elderly patients with diffuse large B-cell lymphoma: a phase I study by the Fondazione Italiana Linfomi

scientific article

Long-Term Follow-Up of Indolent Lymphoma Patients Treated With High-Dose Sequential Chemotherapy and Autografting: Evidence That Durable Molecular and Clinical Remission Frequently Can Be Attained Only in Follicular Subtypes

article

Long-term follow-up of advanced-stage low-grade lymphoma patients treated upfront with high-dose sequential chemotherapy and autograft

scientific article published on 01 April 2000

Long-term lymphoma survivors following high-dose chemotherapy and autograft: evidence of permanent telomere shortening in myeloid cells, associated with marked reduction of bone marrow hematopoietic stem cell reservoir

scientific article published on 01 April 2007

Long-term results of the GIMEMA VEL-03-096 trial in MM patients receiving VTD consolidation after ASCT: MRD kinetics' impact on survival

scientific article published on 16 July 2014

Low CD49d expression and long telomere identify a chronic lymphocytic leukemia subset with highly favourable outcome

scientific article published on 01 August 2010

MET dysregulation is a hallmark of aggressive disease in multiple myeloma patients

scientific article published on 23 January 2014

MGA, a suppressor of MYC, is recurrently inactivated in high risk chronic lymphocytic leukemia

scientific article

MLN3897, a novel CCR1 inhibitor, impairs osteoclastogenesis and inhibits the interaction of multiple myeloma cells and osteoclasts.

scientific article

Marked telomere shortening in mobilized peripheral blood progenitor cells (PBPC) following two tightly spaced high-dose chemotherapy courses with G-CSF.

scientific article

MicroRNAs regulate critical genes associated with multiple myeloma pathogenesis

scientific article

Minimal Residual Disease Detection by Droplet Digital PCR in Multiple Myeloma, Mantle Cell Lymphoma, and Follicular Lymphoma: A Comparison with Real-Time PCR.

scientific article published on 26 August 2015

Minimal residual disease after conventional treatment significantly impacts on progression-free survival of patients with follicular lymphoma: the FIL FOLL05 trial

scientific article

Multiple myeloma shows no intra-disease clustering of immunoglobulin heavy chain genes.

scientific article published on 29 December 2011

N- and K-ras oncogenes in plasma cell dyscrasias.

scientific article published on September 1994

Negative immunomagnetic ex vivo purging combined with high-dose chemotherapy with peripheral blood progenitor cell autograft in follicular lymphoma patients: evidence for long-term clinical and molecular remissions

scientific article published on 01 September 1999

Newly diagnosed and relapsed follicular lymphoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

scientific article published on 01 December 2017

Newly diagnosed and relapsed follicular lymphoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

scientific article published on 01 September 2016

Newly diagnosed and relapsed mantle cell lymphoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

scientific article published in July 2017

Next-generation sequencing and real-time quantitative PCR for minimal residual disease detection in B-cell disorders.

scientific article

Outcome of a Salvage Third Autologous Stem Cell Transplantation in Multiple Myeloma

scientific article published on 2 February 2018

PCR-detectable nonneoplastic Bcl-2/IgH rearrangements are common in normal subjects and cancer patients at diagnosis but rare in subjects treated with chemotherapy.

scientific article

Patients with high-risk aggressive lymphoma treated with frontline intensive chemotherapy and autografting: evidence of marked differences in outcome between patients with age-adjusted International Prognostic Index scores 2 and 3.

scientific article published in September 2003

Peripheral T-cell lymphomas: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

scientific article published on 01 September 2015

Persistence of minimal residual disease in bone marrow predicts outcome in follicular lymphomas treated with a rituximab-intensive program

scientific article published in October 2013

Progressive telomere shortening is part of the natural history of chronic lymphocytic leukaemia and impacts clinical outcome: evidences from long term follow-up.

scientific article published on 2 April 2017

Prolonged survival and low incidence of late toxic sequelae in advanced follicular lymphoma treated with a TBI-free autografting program: updated results of the multicenter consecutive GITMO trial

scientific article published on 24 August 2006

Prolonged survival in poor-risk diffuse large B-cell lymphoma following front-line treatment with rituximab-supplemented, early-intensified chemotherapy with multiple autologous hematopoietic stem cell support: a multicenter study by GITIL (Gruppo I

scientific article published on 7 June 2007

Prospective molecular monitoring of minimal residual disease after non-myeloablative allografting in newly diagnosed multiple myeloma.

scientific article published on 6 October 2015

Qualitative and quantitative polymerase chain reaction detection of the residual myeloma cell contamination after positive selection of CD34+ cells with small- and large-scale Miltenyi cell sorting system

scientific article published on 01 June 2002

Randomized Trial Comparing R-CHOP Versus High-Dose Sequential Chemotherapy in High-Risk Patients With Diffuse Large B-Cell Lymphomas.

scientific article published on 31 October 2016

Real-Time polymerase chain reaction of immunoglobulin rearrangements for quantitative evaluation of minimal residual disease in multiple myeloma

scientific article published on 01 January 2000

Real-time polymerase chain reaction in multiple myeloma: quantitative analysis of tumor contamination of stem cell harvests

scientific article published on 01 June 2002

Recurrence of Bcl-2/IgH polymerase chain reaction positivity following a prolonged molecular remission can be unrelated to the original follicular lymphoma clone.

scientific article

Rituximab induces effective clearance of minimal residual disease in molecular relapses of mantle cell lymphoma.

scientific article

Rituximab maintenance compared with observation after brief first-line R-FND chemoimmunotherapy with rituximab consolidation in patients age older than 60 years with advanced follicular lymphoma: a phase III randomized study by the Fondazione Italia

scientific article published on 19 August 2013

Rituximab, bendamustine, and low-dose cytarabine as induction therapy in elderly patients with mantle cell lymphoma: a multicentre, phase 2 trial from Fondazione Italiana Linfomi

scientific article

Second-line rituximab, lenalidomide, and bendamustine in mantle cell lymphoma: a phase II clinical trial of the Fondazione Italiana Linfomi.

scientific article published on 12 January 2017

Simvastatin and downstream inhibitors circumvent constitutive and stromal cell-induced resistance to doxorubicin in IGHV unmutated CLL cells.

scientific article published on 27 May 2015

Single-agent panobinostat for relapsed/refractory diffuse large B-cell lymphoma: clinical outcome and correlation with genomic data. A phase 2 study of the Fondazione Italiana Linfomi

scientific article published on 04 April 2018

Stem cell transplantation in multiple myeloma and other plasma cell disorders (report from an EBMT preceptorship meeting).

scientific article

Stereotyped B-Cell Receptor Is an Independent Risk Factor of Chronic Lymphocytic Leukemia Transformation to Richter Syndrome

scientific article published on 09 June 2009

Syndecan-1 promotes the angiogenic phenotype of multiple myeloma endothelial cells.

scientific article published on 25 October 2011

Telomere length correlates with histopathogenesis according to the germinal center in mature B-cell lymphoproliferative disorders

scientific article published on 26 February 2004

Telomere length identifies two different prognostic subgroups among VH-unmutated B-cell chronic lymphocytic leukemia patients

scientific article published on 15 February 2007

Telomere length is an independent predictor of survival, treatment requirement and Richter's syndrome transformation in chronic lymphocytic leukemia.

scientific article

Telomere loss in Philadelphia-negative hematopoiesis after successful treatment of chronic myeloid leukemia: evidence for premature aging of the myeloid compartment.

scientific article published on 9 June 2012

Telomeres and telomerase in normal and malignant B-cells.

scientific article published on December 2010

The adulthood of MRD detection in MCL

scientific article published on 01 April 2010

The host genetic background of DNA repair mechanisms is an independent predictor of survival in diffuse large B-cell lymphoma

scientific article

The lymphocyte to monocyte ratio improves the IPI-risk definition of diffuse large B-cell lymphoma when rituximab is added to chemotherapy.

scientific article published on 30 September 2013

The mutation of N-ras oncogene does not involve myeloid and erythroid lineages in a case of multiple myeloma

scientific article published on 01 April 1993

The new tumor-suppressor gene inhibitor of growth family member 4 (ING4) regulates the production of proangiogenic molecules by myeloma cells and suppresses hypoxia-inducible factor-1 alpha (HIF-1alpha) activity: involvement in myeloma-induced angio

scientific article published on 11 September 2007

Thirty-Month Complete Response as a Surrogate End Point in First-Line Follicular Lymphoma Therapy: An Individual Patient-Level Analysis of Multiple Randomized Trials

scientific article

Two main genetic pathways lead to the transformation of chronic lymphocytic leukemia to Richter syndrome.

scientific article published on 4 September 2013

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