List of works - Fabienne Foufelle

A New Role for a Metabolic Star: AMP-Activated Protein Kinase Stimulates Fat Absorption ⬇️

scientific article published on 01 January 2011

A rare missense mutation in a type 2 diabetes patient decreases the transcriptional activity of human sterol regulatory element binding protein-1.

scientific article published in February 2006

AICAR and metformin, but not exercise, increase muscle glucose transport through AMPK-, ERK-, and PDK1-dependent activation of atypical PKC.

scientific article

AJP-cell begins a theme series on cellular mechanisms of endoplasmic reticulum stress signaling in health and disease

scientific article published on 02 July 2014

AMP-activated kinase regulates cytoplasmic HuR.

scientific article

AMP-activated protein kinase activation modulates progesterone secretion in granulosa cells from hen preovulatory follicles.

scientific article

AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus

scientific article

AMPK, an active player in the control of metabolism

scientific article published in January 2006

Activation of GLUT1 by metabolic and osmotic stress: potential involvement of AMP-activated protein kinase (AMPK)

scientific journal article

Adenovirus-mediated overexpression of sterol regulatory element binding protein-1c mimics insulin effects on hepatic gene expression and glucose homeostasis in diabetic mice.

scientific article published in November 2001

Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase

scientific article

Anti-lipolytic action of AMP-activated protein kinase in rodent adipocytes

scientific journal article

Characterising the inhibitory actions of ceramide upon insulin signaling in different skeletal muscle cell models: a mechanistic insight

scientific article

Direct activation of AMP-activated protein kinase stimulates nitric-oxide synthesis in human aortic endothelial cells

scientific article

Distinct regulation of adiponutrin/PNPLA3 gene expression by the transcription factors ChREBP and SREBP1c in mouse and human hepatocytes

article

Distinct roles of insulin and liver X receptor in the induction and cleavage of sterol regulatory element-binding protein-1c

scientific journal article

Effect of diets rich in medium-chain and long-chain triglycerides on lipogenic-enzyme gene expression in liver and adipose tissue of the weaned rat

scientific article published on 01 September 1992

Endoplasmic reticulum proteostasis in hepatic steatosis.

scientific article published on 12 August 2016

Endoplasmic reticulum stress does not mediate palmitate-induced insulin resistance in mouse and human muscle cells ⬇️

scientific article published on October 18, 2011

Endoplasmic reticulum stress, obesity and diabetes

scientific article published on 31 August 2011

Endoplasmic reticulum stress: a new actor in the development of hepatic steatosis.

scientific article published on June 2010

Endoplasmic reticulum stress: from physiology to pathogenesis of type 2 diabetes

scientific article published in August 2013

Extracellular adenosine activates AMP-dependent protein kinase (AMPK).

scientific article published on 28 March 2006

Functions of AMP-activated protein kinase in adipose tissue.

scientific article

GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in mice

scientific article published on 13 April 2009

GRP78 rescues the ABCG5 ABCG8 sterol transporter in db/db mice

scientific article

Glucose 6-phosphate, rather than xylulose 5-phosphate, is required for the activation of ChREBP in response to glucose in the liver

scientific article published on 09 August 2011

Hepatic glucokinase is required for the synergistic action of ChREBP and SREBP-1c on glycolytic and lipogenic gene expression

scientific article published on 25 February 2004

Hepatic insulin signaling is required for obesity-dependent expression of SREBP-1c mRNA but not for feeding-dependent expression

scientific article

Hepatic n-3 polyunsaturated fatty acid depletion promotes steatosis and insulin resistance in mice: genomic analysis of cellular targets

scientific article

Hepatic steatosis: a role for de novo lipogenesis and the transcription factor SREBP-1c

scientific article

Hepatic stellate cell hypertrophy is associated with metabolic liver fibrosis

scientific article published on 02 March 2020

Hepatitis C Virus Proteins Induce Lipogenesis and Defective Triglyceride Secretion in Transgenic Mice

scientific article (publication date: 27 November 2009)

Hepatitis C virus induces a prediabetic state by directly impairing hepatic glucose metabolism in mice.

scientific article

High carbohydrate diet induces nonalcoholic steato-hepatitis (NASH) in a desert gerbil.

scientific article

Hypothalamic AgRP-neurons control peripheral substrate utilization and nutrient partitioning

scientific article

IRF5 governs liver macrophage activation that promotes hepatic fibrosis in mice and humans.

scientific article published on 08 December 2016

In vitro transcriptional induction of the human apolipoprotein A-II gene by glucose

scientific article

Induction of fatty acid synthase and S14 gene expression by glucose, xylitol and dihydroxyacetone in cultured rat hepatocytes is closely correlated with glucose 6-phosphate concentrations.

scientific article published on September 1997

Induction of fatty-acid-synthase gene expression by glucose in primary culture of rat hepatocytes. Dependency upon glucokinase activity

scientific article published on 01 May 1995

Influence of diet on the development and regulation of lipogenic enzymes in adipose tissue.

scientific article published on December 1992

Insulin effects on sterol regulatory-element-binding protein-1c (SREBP-1c) transcriptional activity in rat hepatocytes.

scientific article published in September 2000

Irf5 deficiency in macrophages promotes beneficial adipose tissue expansion and insulin sensitivity during obesity.

scientific article

Ketosis-prone type 2 diabetes mellitus and human herpesvirus 8 infection in sub-saharan africans.

scientific article published on June 2008

Laforin, a dual specificity phosphatase involved in Lafora disease, regulates insulin response and whole-body energy balance in mice.

scientific article published on 14 April 2011

Lipid environment induces ER stress, TXNIP expression and inflammation in immune cells of individuals with type 2 diabetes

scientific article

Liver-specific inhibition of ChREBP improves hepatic steatosis and insulin resistance in ob/ob mice.

scientific article published on August 2006

Long chain fatty acyl-CoA synthetase 5 expression is induced by insulin and glucose: involvement of sterol regulatory element-binding protein-1c

scientific journal article

Loss of the co-repressor GPS2 sensitizes macrophage activation upon metabolic stress induced by obesity and type 2 diabetes

scientific article

Metformin-induced stimulation of adenosine 5' monophosphate-activated protein kinase (PRKA) impairs progesterone secretion in rat granulosa cells

scientific journal article

Mimicry of a cellular low energy status blocks tumor cell anabolism and suppresses the malignant phenotype

scientific article published on 2005

Molecular phenomics and metagenomics of hepatic steatosis in non-diabetic obese women

scientific article published on 25 June 2018

New insights into ER stress-induced insulin resistance.

scientific article published on 04 July 2012

Novel insights in the interplay between inflammation and metabolic diseases: a role for the pathogen sensing kinase PKR

scientific article published on 17 February 2011

Over-expression of sterol-regulatory-element-binding protein-1c (SREBP1c) in rat pancreatic islets induces lipogenesis and decreases glucose-stimulated insulin release: modulation by 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR).

scientific article

Oxidative and energetic stresses mediate beta-cell dysfunction induced by PGC-1α.

scientific article published in March 2017

Pioglitazone induces in vivo adipocyte differentiation in the obese Zucker fa/fa rat.

scientific article published on September 1997

Pioglitazone-induced increase of insulin sensitivity in the muscles of the obese Zucker fa/fa rat cannot be explained by local adipocyte differentiation

scientific article published in August 1998

Polyunsaturated fatty acids inhibit fatty acid synthase and spot-14-protein gene expression in cultured rat hepatocytes by a peroxidative mechanism.

scientific article published on July 1999

Polyunsaturated fatty acids suppress glycolytic and lipogenic genes through the inhibition of ChREBP nuclear protein translocation

scientific article published on 22 September 2005

Regulation of carbohydrate metabolism by insulin: role of transcription factor SREBP-1c in the hepatic transcriptional effects of the hormone

scientific article published in January 2001

Regulation of lipogenic enzyme and phosphoenolpyruvate carboxykinase gene expression in cultured white adipose tissue. Glucose and insulin effects are antagonized by cAMP.

scientific article

Regulation of lipogenic enzyme expression by glucose in liver and adipose tissue: is glucose 6-phosphate the signalling metabolite?

scientific article

Residue specific effects of human islet polypeptide amyloid on self-assembly and on cell toxicity.

scientific article published on 2 August 2017

Role of endoplasmic reticulum stress in drug-induced toxicity

scientific article

SETDB2 Links Glucocorticoid to Lipid Metabolism through Insig2a Regulation

scientific article

SREBF-1 gene polymorphisms are associated with obesity and type 2 diabetes in French obese and diabetic cohorts

scientific article published on 01 August 2004

SREBP transcription factors: master regulators of lipid homeostasis

scientific article

SREBP-1 regulates the expression of heme oxygenase 1 and the phosphatidylinositol-3 kinase regulatory subunit p55 gamma

scientific article

SREBP-1c transcription factor and lipid homeostasis: clinical perspective

scientific article

Sterol regulatory element binding protein-1c expression and action in rat muscles: insulin-like effects on the control of glycolytic and lipogenic enzymes and UCP3 gene expression

scientific article published in June 2002

Sterol regulatory element binding protein-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis-related genes

scientific article

Sterol regulatory element-binding protein-1c mimics the negative effect of insulin on phosphoenolpyruvate carboxykinase (GTP) gene transcription

article

Stimulation of acetyl-CoA carboxylase gene expression by glucose requires insulin release and sterol regulatory element binding protein 1c in pancreatic MIN6 beta-cells

scientific article published on August 2002

Stimulation of tumor-associated fatty acid synthase expression by growth factor activation of the sterol regulatory element-binding protein pathway

scientific article published on 01 October 2000

Study of the regulation by nutrients of the expression of genes involved in lipogenesis and obesity in humans and animals.

scientific article

Sustained Action of Ceramide on the Insulin Signaling Pathway in Muscle Cells: IMPLICATION OF THE DOUBLE-STRANDED RNA-ACTIVATED PROTEIN KINASE

scientific article

Synthesis and biological evaluation of benzimidazole derivatives as potent AMP-activated protein kinase activators

scientific article published on 2 March 2006

The inhibitory effect of glucose on phosphoenolpyruvate carboxykinase gene expression in cultured hepatocytes is transcriptional and requires glucose metabolism

scientific article published on 01 November 1999

The polymorphism Arg585Gln in the gene of the sterol regulatory element binding protein-1 (SREBP-1) is not a determinant of ketosis prone type 2 diabetes (KPD) in Africans.

scientific article

Vasopressin and hydration play a major role in the development of glucose intolerance and hepatic steatosis in obese rats

scientific article published on 27 January 2015

[A new role for insulin in the control of energetic metabolism in liver]

scientific article published on 01 June 2005

[Importance of phospholipids in ER stress and fatty liver disease].

scientific article published on 27 January 2012

[Introduction to molecular biology. Vocabulary and basic concepts]

scientific article published on 01 March 1992

[Regulation of expression of genes coding for lipogenesis enzymes during development in the rat]

scientific article published on 01 January 1995

[Unfolded protein response: its role in physiology and physiopathology]

scientific article published on 01 March 2007

List of works by Fabienne Foufelle

A New Role for a Metabolic Star: AMP-Activated Protein Kinase Stimulates Fat Absorption ⬇️

A rare missense mutation in a type 2 diabetes patient decreases the transcriptional activity of human sterol regulatory element binding protein-1.

AICAR and metformin, but not exercise, increase muscle glucose transport through AMPK-, ERK-, and PDK1-dependent activation of atypical PKC.

AJP-cell begins a theme series on cellular mechanisms of endoplasmic reticulum stress signaling in health and disease

AMP-activated kinase regulates cytoplasmic HuR.

AMP-activated protein kinase activation modulates progesterone secretion in granulosa cells from hen preovulatory follicles.

AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus

AMPK, an active player in the control of metabolism

Activation of GLUT1 by metabolic and osmotic stress: potential involvement of AMP-activated protein kinase (AMPK)

Adenovirus-mediated overexpression of sterol regulatory element binding protein-1c mimics insulin effects on hepatic gene expression and glucose homeostasis in diabetic mice.

Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase

Anti-lipolytic action of AMP-activated protein kinase in rodent adipocytes

Characterising the inhibitory actions of ceramide upon insulin signaling in different skeletal muscle cell models: a mechanistic insight

Direct activation of AMP-activated protein kinase stimulates nitric-oxide synthesis in human aortic endothelial cells

Distinct regulation of adiponutrin/PNPLA3 gene expression by the transcription factors ChREBP and SREBP1c in mouse and human hepatocytes

Distinct roles of insulin and liver X receptor in the induction and cleavage of sterol regulatory element-binding protein-1c

Effect of diets rich in medium-chain and long-chain triglycerides on lipogenic-enzyme gene expression in liver and adipose tissue of the weaned rat

Endoplasmic reticulum proteostasis in hepatic steatosis.

Endoplasmic reticulum stress does not mediate palmitate-induced insulin resistance in mouse and human muscle cells ⬇️

Endoplasmic reticulum stress, obesity and diabetes

Endoplasmic reticulum stress: a new actor in the development of hepatic steatosis.

Endoplasmic reticulum stress: from physiology to pathogenesis of type 2 diabetes

Extracellular adenosine activates AMP-dependent protein kinase (AMPK).

Functions of AMP-activated protein kinase in adipose tissue.

GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in mice

GRP78 rescues the ABCG5 ABCG8 sterol transporter in db/db mice

Glucose 6-phosphate, rather than xylulose 5-phosphate, is required for the activation of ChREBP in response to glucose in the liver

Hepatic glucokinase is required for the synergistic action of ChREBP and SREBP-1c on glycolytic and lipogenic gene expression

Hepatic insulin signaling is required for obesity-dependent expression of SREBP-1c mRNA but not for feeding-dependent expression

Hepatic n-3 polyunsaturated fatty acid depletion promotes steatosis and insulin resistance in mice: genomic analysis of cellular targets

Hepatic steatosis: a role for de novo lipogenesis and the transcription factor SREBP-1c

Hepatic stellate cell hypertrophy is associated with metabolic liver fibrosis

Hepatitis C Virus Proteins Induce Lipogenesis and Defective Triglyceride Secretion in Transgenic Mice

Hepatitis C virus induces a prediabetic state by directly impairing hepatic glucose metabolism in mice.

High carbohydrate diet induces nonalcoholic steato-hepatitis (NASH) in a desert gerbil.

Hypothalamic AgRP-neurons control peripheral substrate utilization and nutrient partitioning

IRF5 governs liver macrophage activation that promotes hepatic fibrosis in mice and humans.

In vitro transcriptional induction of the human apolipoprotein A-II gene by glucose

Induction of fatty acid synthase and S14 gene expression by glucose, xylitol and dihydroxyacetone in cultured rat hepatocytes is closely correlated with glucose 6-phosphate concentrations.

Induction of fatty-acid-synthase gene expression by glucose in primary culture of rat hepatocytes. Dependency upon glucokinase activity

Influence of diet on the development and regulation of lipogenic enzymes in adipose tissue.

Insulin effects on sterol regulatory-element-binding protein-1c (SREBP-1c) transcriptional activity in rat hepatocytes.

Irf5 deficiency in macrophages promotes beneficial adipose tissue expansion and insulin sensitivity during obesity.

Ketosis-prone type 2 diabetes mellitus and human herpesvirus 8 infection in sub-saharan africans.

Laforin, a dual specificity phosphatase involved in Lafora disease, regulates insulin response and whole-body energy balance in mice.

Lipid environment induces ER stress, TXNIP expression and inflammation in immune cells of individuals with type 2 diabetes

Liver-specific inhibition of ChREBP improves hepatic steatosis and insulin resistance in ob/ob mice.

Long chain fatty acyl-CoA synthetase 5 expression is induced by insulin and glucose: involvement of sterol regulatory element-binding protein-1c

Loss of the co-repressor GPS2 sensitizes macrophage activation upon metabolic stress induced by obesity and type 2 diabetes

Metformin-induced stimulation of adenosine 5' monophosphate-activated protein kinase (PRKA) impairs progesterone secretion in rat granulosa cells

Mimicry of a cellular low energy status blocks tumor cell anabolism and suppresses the malignant phenotype

Molecular phenomics and metagenomics of hepatic steatosis in non-diabetic obese women

New insights into ER stress-induced insulin resistance.

Novel insights in the interplay between inflammation and metabolic diseases: a role for the pathogen sensing kinase PKR

Over-expression of sterol-regulatory-element-binding protein-1c (SREBP1c) in rat pancreatic islets induces lipogenesis and decreases glucose-stimulated insulin release: modulation by 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR).

Oxidative and energetic stresses mediate beta-cell dysfunction induced by PGC-1α.

Pioglitazone induces in vivo adipocyte differentiation in the obese Zucker fa/fa rat.

Pioglitazone-induced increase of insulin sensitivity in the muscles of the obese Zucker fa/fa rat cannot be explained by local adipocyte differentiation

Polyunsaturated fatty acids inhibit fatty acid synthase and spot-14-protein gene expression in cultured rat hepatocytes by a peroxidative mechanism.

Polyunsaturated fatty acids suppress glycolytic and lipogenic genes through the inhibition of ChREBP nuclear protein translocation

Regulation of carbohydrate metabolism by insulin: role of transcription factor SREBP-1c in the hepatic transcriptional effects of the hormone

Regulation of lipogenic enzyme and phosphoenolpyruvate carboxykinase gene expression in cultured white adipose tissue. Glucose and insulin effects are antagonized by cAMP.

Regulation of lipogenic enzyme expression by glucose in liver and adipose tissue: is glucose 6-phosphate the signalling metabolite?

Residue specific effects of human islet polypeptide amyloid on self-assembly and on cell toxicity.

Role of endoplasmic reticulum stress in drug-induced toxicity

SETDB2 Links Glucocorticoid to Lipid Metabolism through Insig2a Regulation

SREBF-1 gene polymorphisms are associated with obesity and type 2 diabetes in French obese and diabetic cohorts

SREBP transcription factors: master regulators of lipid homeostasis

SREBP-1 regulates the expression of heme oxygenase 1 and the phosphatidylinositol-3 kinase regulatory subunit p55 gamma

SREBP-1c transcription factor and lipid homeostasis: clinical perspective

Sterol regulatory element binding protein-1c expression and action in rat muscles: insulin-like effects on the control of glycolytic and lipogenic enzymes and UCP3 gene expression

Sterol regulatory element binding protein-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis-related genes

Sterol regulatory element-binding protein-1c mimics the negative effect of insulin on phosphoenolpyruvate carboxykinase (GTP) gene transcription

Stimulation of acetyl-CoA carboxylase gene expression by glucose requires insulin release and sterol regulatory element binding protein 1c in pancreatic MIN6 beta-cells

Stimulation of tumor-associated fatty acid synthase expression by growth factor activation of the sterol regulatory element-binding protein pathway

Study of the regulation by nutrients of the expression of genes involved in lipogenesis and obesity in humans and animals.

Sustained Action of Ceramide on the Insulin Signaling Pathway in Muscle Cells: IMPLICATION OF THE DOUBLE-STRANDED RNA-ACTIVATED PROTEIN KINASE

Synthesis and biological evaluation of benzimidazole derivatives as potent AMP-activated protein kinase activators

The inhibitory effect of glucose on phosphoenolpyruvate carboxykinase gene expression in cultured hepatocytes is transcriptional and requires glucose metabolism