List of works - Bekh Bradley

Allele-specific FKBP5 DNA demethylation mediates gene-childhood trauma interactions

scientific article

Post-traumatic stress disorder is associated with PACAP and the PAC1 receptor

scientific article

Childhood maltreatment is associated with distinct genomic and epigenetic profiles in posttraumatic stress disorder

scientific article

Trauma exposure and stress-related disorders in inner city primary care patients

scientific article published on 09 June 2009

Impaired fear inhibition is a biomarker of PTSD but not depression

scientific article

Risk and resilience: genetic and environmental influences on development of the stress response.

scientific article

Differential immune system DNA methylation and cytokine regulation in post-traumatic stress disorder.

scientific article published on 28 June 2011

Fear extinction in traumatized civilians with posttraumatic stress disorder: relation to symptom severity

scientific article

Effect of Childhood Trauma on Adult Depression and Neuroendocrine Function: Sex-Specific Moderation by CRH Receptor 1 Gene

scientific article

DNA extracted from saliva for methylation studies of psychiatric traits: evidence tissue specificity and relatedness to brain

scientific article

Disrupted amygdala-prefrontal functional connectivity in civilian women with posttraumatic stress disorder.

scientific article published on July 2013

Lifetime stress accelerates epigenetic aging in an urban, African American cohort: relevance of glucocorticoid signaling.

scientific article

Using polymorphisms in FKBP5 to define biologically distinct subtypes of posttraumatic stress disorder: evidence from endocrine and gene expression studies

scientific article

The neuronal transporter gene SLC6A15 confers risk to major depression

scientific article

A randomized, double-blind evaluation of D-cycloserine or alprazolam combined with virtual reality exposure therapy for posttraumatic stress disorder in Iraq and Afghanistan War veterans

scientific article

Substance use, childhood traumatic experience, and Posttraumatic Stress Disorder in an urban civilian population.

scientific article

Moderating effects of resilience on depression in individuals with a history of childhood abuse or trauma exposure

scientific article published on 21 May 2010

Estrogen levels are associated with extinction deficits in women with posttraumatic stress disorder

scientific article

Association between childhood maltreatment and adult emotional dysregulation in a low-income, urban, African American sample: Moderation by oxytocin receptor gene

scientific article published on May 1, 2011

Emotion dysregulation and negative affect: association with psychiatric symptoms

scientific article

Neural correlates of attention bias to threat in post-traumatic stress disorder

scientific article published on 10 March 2012

PTSD and gene variants: new pathways and new thinking.

scientific article

FKBP5 and attention bias for threat: associations with hippocampal function and shape

scientific article published on April 2013

PACAP receptor gene polymorphism impacts fear responses in the amygdala and hippocampus

scientific article published on 10 February 2014

Reduced neural activation during an inhibition task is associated with impaired fear inhibition in a traumatized civilian sample.

scientific article

Association of CRP genetic variation and CRP level with elevated PTSD symptoms and physiological responses in a civilian population with high levels of trauma

scientific article

Polymorphisms in CRHR1 and the serotonin transporter loci: gene x gene x environment interactions on depressive symptoms

scientific article

Amygdala-dependent fear is regulated by Oprl1 in mice and humans with PTSD.

scientific article

Association of polymorphisms in genes regulating the corticotropin-releasing factor system with antidepressant treatment response.

scientific article

ADCYAP1R1 genotype associates with post-traumatic stress symptoms in highly traumatized African-American females

scientific article published on 15 March 2013

Childhood abuse is associated with increased startle reactivity in adulthood

scientific article

White matter integrity in highly traumatized adults with and without post-traumatic stress disorder.

scientific article

Fear potentiation is associated with hypothalamic-pituitary-adrenal axis function in PTSD

scientific article

Differential Genetic and Epigenetic Regulation of catechol-O-methyltransferase is Associated with Impaired Fear Inhibition in Posttraumatic Stress Disorder.

scientific article

Perceived neighborhood disorder, community cohesion, and PTSD symptoms among low-income African Americans in an urban health setting

scientific article

Posttraumatic stress disorder is a risk factor for metabolic syndrome in an impoverished urban population

scientific article

A genome-wide identified risk variant for PTSD is a methylation quantitative trait locus and confers decreased cortical activation to fearful faces

scientific article published on 18 May 2015

Tools for translational neuroscience: PTSD is associated with heightened fear responses using acoustic startle but not skin conductance measures

scientific article

Oxytocin Receptor Genetic and Epigenetic Variations: Association With Child Abuse and Adult Psychiatric Symptoms

scientific article published on January 2016

The renin-angiotensin pathway in posttraumatic stress disorder: angiotensin-converting enzyme inhibitors and angiotensin receptor blockers are associated with fewer traumatic stress symptoms

scientific article

Physiological markers of anxiety are increased in children of abused mothers

scientific article

Gene × Environment Determinants of Stress- and Anxiety-Related Disorders

scientific article published on 06 October 2015

Development of fear acquisition and extinction in children: Effects of age and anxiety

scientific article published on October 29, 2013

FKBP5 genotype and structural integrity of the posterior cingulum

scientific article

DICER1 and microRNA regulation in post-traumatic stress disorder with comorbid depression.

scientific article published on 3 December 2015

Fear load: The psychophysiological over-expression of fear as an intermediate phenotype associated with trauma reactions.

scientific article

Inhibition of fear is differentially associated with cycling estrogen levels in women

scientific article

Pain symptomatology and pain medication use in civilian PTSD.

scientific article

Fear-potentiated startle during extinction is associated with white matter microstructure and functional connectivity.

scientific article

The mediating role of emotion dysregulation and depression on the relationship between childhood trauma exposure and emotional eating

scientific article published on 9 April 2015

List of works by Bekh Bradley

Allele-specific FKBP5 DNA demethylation mediates gene-childhood trauma interactions

Post-traumatic stress disorder is associated with PACAP and the PAC1 receptor

Childhood maltreatment is associated with distinct genomic and epigenetic profiles in posttraumatic stress disorder

Trauma exposure and stress-related disorders in inner city primary care patients

Impaired fear inhibition is a biomarker of PTSD but not depression

Risk and resilience: genetic and environmental influences on development of the stress response.

Differential immune system DNA methylation and cytokine regulation in post-traumatic stress disorder.

Fear extinction in traumatized civilians with posttraumatic stress disorder: relation to symptom severity

Effect of Childhood Trauma on Adult Depression and Neuroendocrine Function: Sex-Specific Moderation by CRH Receptor 1 Gene

DNA extracted from saliva for methylation studies of psychiatric traits: evidence tissue specificity and relatedness to brain

Disrupted amygdala-prefrontal functional connectivity in civilian women with posttraumatic stress disorder.

Lifetime stress accelerates epigenetic aging in an urban, African American cohort: relevance of glucocorticoid signaling.

Using polymorphisms in FKBP5 to define biologically distinct subtypes of posttraumatic stress disorder: evidence from endocrine and gene expression studies

The neuronal transporter gene SLC6A15 confers risk to major depression

A randomized, double-blind evaluation of D-cycloserine or alprazolam combined with virtual reality exposure therapy for posttraumatic stress disorder in Iraq and Afghanistan War veterans

Substance use, childhood traumatic experience, and Posttraumatic Stress Disorder in an urban civilian population.

Moderating effects of resilience on depression in individuals with a history of childhood abuse or trauma exposure

Estrogen levels are associated with extinction deficits in women with posttraumatic stress disorder

Association between childhood maltreatment and adult emotional dysregulation in a low-income, urban, African American sample: Moderation by oxytocin receptor gene

Emotion dysregulation and negative affect: association with psychiatric symptoms

Neural correlates of attention bias to threat in post-traumatic stress disorder

PTSD and gene variants: new pathways and new thinking.

FKBP5 and attention bias for threat: associations with hippocampal function and shape

PACAP receptor gene polymorphism impacts fear responses in the amygdala and hippocampus

Reduced neural activation during an inhibition task is associated with impaired fear inhibition in a traumatized civilian sample.

Association of CRP genetic variation and CRP level with elevated PTSD symptoms and physiological responses in a civilian population with high levels of trauma

Polymorphisms in CRHR1 and the serotonin transporter loci: gene x gene x environment interactions on depressive symptoms

Amygdala-dependent fear is regulated by Oprl1 in mice and humans with PTSD.

Association of polymorphisms in genes regulating the corticotropin-releasing factor system with antidepressant treatment response.

ADCYAP1R1 genotype associates with post-traumatic stress symptoms in highly traumatized African-American females

Childhood abuse is associated with increased startle reactivity in adulthood

White matter integrity in highly traumatized adults with and without post-traumatic stress disorder.

Fear potentiation is associated with hypothalamic-pituitary-adrenal axis function in PTSD

Differential Genetic and Epigenetic Regulation of catechol-O-methyltransferase is Associated with Impaired Fear Inhibition in Posttraumatic Stress Disorder.

Perceived neighborhood disorder, community cohesion, and PTSD symptoms among low-income African Americans in an urban health setting

Posttraumatic stress disorder is a risk factor for metabolic syndrome in an impoverished urban population

A genome-wide identified risk variant for PTSD is a methylation quantitative trait locus and confers decreased cortical activation to fearful faces

Tools for translational neuroscience: PTSD is associated with heightened fear responses using acoustic startle but not skin conductance measures

Oxytocin Receptor Genetic and Epigenetic Variations: Association With Child Abuse and Adult Psychiatric Symptoms

The renin-angiotensin pathway in posttraumatic stress disorder: angiotensin-converting enzyme inhibitors and angiotensin receptor blockers are associated with fewer traumatic stress symptoms

Physiological markers of anxiety are increased in children of abused mothers

Gene × Environment Determinants of Stress- and Anxiety-Related Disorders

Development of fear acquisition and extinction in children: Effects of age and anxiety

FKBP5 genotype and structural integrity of the posterior cingulum

DICER1 and microRNA regulation in post-traumatic stress disorder with comorbid depression.

Fear load: The psychophysiological over-expression of fear as an intermediate phenotype associated with trauma reactions.

Inhibition of fear is differentially associated with cycling estrogen levels in women

Pain symptomatology and pain medication use in civilian PTSD.

Fear-potentiated startle during extinction is associated with white matter microstructure and functional connectivity.

The mediating role of emotion dysregulation and depression on the relationship between childhood trauma exposure and emotional eating