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List of works by Olivier Dormond

ATP-competitive inhibitors of mTOR: new perspectives in the treatment of renal cell carcinoma

scientific article published on April 2011

Acidic pH reduces VEGF-mediated endothelial cell responses by downregulation of VEGFR-2; relevance for anti-angiogenic therapies.

scientific article

Acidic tumor microenvironment abrogates the efficacy of mTORC1 inhibitors

scientific article (publication date: 5 December 2016)

Antitumor activities of ATP-competitive inhibitors of mTOR in colon cancer cells

scientific article

Antitumoral Effect of Sunitinib-eluting Beads in the Rabbit VX2 Tumor Model.

scientific article published on 26 February 2016

Ascending aortic remodelling in Fabry disease after long-term enzyme replacement therapy

scientific article

CD40-induced signaling in human endothelial cells results in mTORC2- and Akt-dependent expression of vascular endothelial growth factor in vitro and in vivo

scientific article

Calcineurin inhibitors activate the proto-oncogene Ras and promote protumorigenic signals in renal cancer cells

scientific article

Characterization of Renal Cell Carcinoma Heterotypic 3D Co-Cultures with Immune Cell Subsets

scientific article published on 24 May 2021

Chemokine receptor trio: CXCR3, CXCR4 and CXCR7 crosstalk via CXCL11 and CXCL12.

scientific article

DLL4 promotes continuous adult intestinal lacteal regeneration and dietary fat transport

scientific article

Diclofenac Potentiates Sorafenib-Based Treatments of Hepatocellular Carcinoma by Enhancing Oxidative Stress

scientific article published on 27 September 2019

Drug Repurposing to Identify a Synergistic High-Order Drug Combination to Treat Sunitinib-Resistant Renal Cell Carcinoma ⬇️

scientific article

Drug-eluting beads loaded with antiangiogenic agents for chemoembolization: in vitro sunitinib loading and release and in vivo pharmacokinetics in an animal model.

scientific article published on 24 January 2014

Endothelial cell integrins and COX-2: mediators and therapeutic targets of tumor angiogenesis.

scientific article published on March 2004

Evolving Significance and Future Relevance of Anti-Angiogenic Activity of mTOR Inhibitors in Cancer Therapy.

scientific article published in November 2017

Fine-Tuning Tumor Endothelial Cells to Selectively Kill Cancer.

scientific article published on 30 June 2017

Hypermobile Ehlers-Danlos-like syndrome in Fabry disease

scientific article published on 15 January 2019

Images in emergency medicine. Giant pulmonary bulla

scientific article published on 01 June 2005

Integrating Phenotypic Search and Phosphoproteomic Profiling of Active Kinases for Optimization of Drug Mixtures for RCC Treatment

scientific article published on 21 September 2020

Invited commentary

Long-term follow-up of pulmonary function in Fabry disease: A bi-center observational study.

scientific article

Manganese-induced integrin affinity maturation promotes recruitment of alpha V beta 3 integrin to focal adhesions in endothelial cells: evidence for a role of phosphatidylinositol 3-kinase and Src

scientific article published on 01 July 2004

Mechanotransduction, PROX1, and FOXC2 cooperate to control connexin37 and calcineurin during lymphatic-valve formation.

scientific article published on 2 February 2012

Modulation of cdk2, cyclin D1, p16INK4a, p21WAF and p27Kip1 expression in endothelial cells by TNF/IFN gamma.

scientific article published in November 2002

Modulation of mTOR Signalling Triggers the Formation of Stem Cell-like Memory T Cells

scientific article published on 16 January 2016

Molecular and Functional Analysis of Sunitinib-Resistance Induction in Human Renal Cell Carcinoma Cells ⬇️

scientific article

NSAIDs inhibit alpha V beta 3 integrin-mediated and Cdc42/Rac-dependent endothelial-cell spreading, migration and angiogenesis.

scientific article

PGE2-induced colon cancer growth is mediated by mTORC1.

scientific article published on 13 August 2014

PI3K and AKT: Unfaithful Partners in Cancer

scientific article

Rapamycin-mediated FOXO1 inactivation reduces the anticancer efficacy of rapamycin.

scientific article published on March 2010

Rapid optimization of drug combinations for the optimal angiostatic treatment of cancer

scientific article published on April 2015

Reactivation of AKT signaling following treatment of cancer cells with PI3K inhibitors attenuates their antitumor effects

scientific article published on 15 July 2013

Rebound pathway overactivation by cancer cells following discontinuation of PI3K or mTOR inhibition promotes cancer cell growth

scientific article published on 10 April 2019

Regulation of endothelial cell integrin function and angiogenesis by COX-2, cAMP and Protein Kinase A

scientific article published on 01 October 2003

Resistance to mTORC1 Inhibitors in Cancer Therapy: From Kinase Mutations to Intratumoral Heterogeneity of Kinase Activity

scientific article published on 09 February 2017

Short-term 3D culture systems of various complexity for treatment optimization of colorectal carcinoma

article

Suppression of tumor angiogenesis by nonsteroidal anti-inflammatory drugs: a new function for old drugs

scientific article published on 01 December 2001

Suppression of tumor angiogenesis through the inhibition of integrin function and signaling in endothelial cells: which side to target?

scientific article

Targeting carbonic anhydrase IX improves the anti-cancer efficacy of mTOR inhibitors

scientific article (publication date: 14 June 2016)

Targeting mTORC2 inhibits colon cancer cell proliferation in vitro and tumor formation in vivo

scientific article

Targeting renal cell carcinoma with NVP-BEZ235, a dual PI3K/mTOR inhibitor, in combination with sorafenib

scientific article

Targeting the JNK signaling pathway potentiates the antiproliferative efficacy of rapamycin in LS174T colon cancer cells.

scientific article published on 5 February 2011

Targeting the Mammalian Target of Rapamycin (mTOR) in Cancer Therapy: Lessons from Past and Future Perspectives

scientific article published on 24 May 2011

Targeting the intragraft microenvironment and the development of chronic allograft rejection

scientific article

The inhibition of MAPK potentiates the anti-angiogenic efficacy of mTOR inhibitors

scientific article published on 23 March 2011

Thoracic aortic dilation/aneurysm in Fabry disease

scientific article published in December 2013

Tumor heterogeneity and cancer stem cell paradigm: updates in concept, controversies and clinical relevance.

scientific article published on 04 March 2014

Zoledronate sensitizes endothelial cells to tumor necrosis factor-induced programmed cell death: evidence for the suppression of sustained activation of focal adhesion kinase and protein kinase B/Akt

scientific article published on 20 August 2003

mTOR and Tumor Cachexia

scientific article published on 30 July 2018

mTOR in Human Diseases ⬇️

scientific article published on 11 May 2019

mTOR-understanding the clinical effects.

scientific article

mTORC2 regulates PGE2-mediated endothelial cell survival and migration

scientific article published on 6 June 2008

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