Search filters

List of works by Martin Christian Michel

A Systematic Comparison of the Properties of Clinically Used Angiotensin II Type 1 Receptor Antagonists ⬇️

scientific article published on March 13, 2013

A Systematic Review of Inverse Agonism at Adrenoceptor Subtypes

scientific article published on 19 August 2020

A comprehensive review of the pharmacodynamics of the SGLT2 inhibitor empagliflozin in animals and humans

scientific article published on 26 June 2015

A comprehensive review of the preclinical efficacy profile of the ErbB family blocker afatinib in cancer

scientific article

A contemporary assessment of nocturia: definition, epidemiology, pathophysiology, and management--a systematic review and meta-analysis

scientific article

A mitogen-activated protein kinase is involved in the inotropic but not chronotropic actions of adrenoceptor agonists and endothelin-1.

scientific article

A role for muscarinic receptors or rho-kinase in hypertension associated rat bladder dysfunction?

scientific article published in June 2005

A systematic review of urinary bladder hypertrophy in experimental diabetes: Part 2. Comparison of animal models and functional consequences

scientific article published on 28 August 2018

A systematic review of urinary bladder hypertrophy in experimental diabetes: Part I. Streptozotocin-induced rat models

scientific article published on 2 February 2018

Activation of sphingosine kinase by muscarinic receptors enhances NO-mediated and attenuates EDHF-mediated vasorelaxation

scientific article published on 5 September 2008

Agonist high- and low-affinity states of dopamine D2 receptors: methods of detection and clinical implications ⬇️

scientific article published on 09 December 2012

Agonist signalling properties of radiotracers used for imaging of dopamine D2/3 receptors

scientific article published on 7 October 2014

Agonist-induced desensitisation of β3 -adrenoceptors: Where, when, and how?

scientific article published on 07 April 2019

Agonist-induced desensitization of human β3-adrenoceptors expressed in human embryonic kidney cells ⬇️

scientific article published on June 12, 2013

An anthology from Naunyn-Schmiedeberg's Archives of Pharmacology

scientific article published in May 2006

An invitation for comprehensive single-compound reviews on the pharmacological properties of newly launched drugs

scholarly article by Martin C. Michel et al published 22 September 2013 in Naunyn-Schmiedeberg's Archives of Pharmacology

Angiotensin II type 1 receptor antagonists in animal models of vascular, cardiac, metabolic and renal disease

scientific article

Apoptosis induction by doxazosin and other quinazoline alpha1-adrenoceptor antagonists: a new mechanism for cancer treatment?

scientific article

Are "functionally related polymorphisms" of renin-angiotensin-aldosterone system gene polymorphisms associated with hypertension?

scientific article

Are RGS2 gene polymorphisms associated with high blood pressure in an ethnicity- and gender-specific manner?

scientific article

Are polymorphisms of the β3‐adrenoceptor gene associated with an altered bladder function? ⬇️

scientific article published on September 12, 2012

Association of hypertension with symptoms of benign prostatic hyperplasia

scientific article

Basic mechanisms of urgency: preclinical and clinical evidence

scientific article published on 26 May 2009

Biased agonism in drug discovery - is it too soon to choose a path?

scientific article published on 11 January 2018

Cardiac and Vascular α1-Adrenoceptors in Congestive Heart Failure: A Systematic Review

scientific article published on 04 November 2020

Cardiac β3 -adrenoceptors-A role in human pathophysiology?

scientific article published on 22 April 2019

Characterization of differential patient profiles and therapeutic responses of pharmacy customers for four ambroxol formulations.

scientific article published on 4 July 2018

Choice of y-axis can mislead readers

scientific article published on 25 June 2020

Cholinergic innervation and muscarinic receptors in the human prostate

scientific article published on 17 December 2007

Commentary on the BJP's new statistical reporting guidelines

scientific article published on 01 September 2018

Comparison of problem-and lecture-based pharmacology teaching

scientific article

Comparison of symptom severity and treatment response in patients with incontinent and continent overactive bladder

scientific article published on 15 December 2004

Comparison of the cardiovascular effects of tamsulosin oral controlled absorption system (OCAS) and alfuzosin prolonged release (XL).

scientific article published on 6 January 2006

Comparison of three radioligands for the labelling of human beta-adrenoceptor subtypes

scientific article published on 7 October 2006

Cyclic AMP-dependent and Epac-mediated activation of R-Ras by G protein-coupled receptors leads to phospholipase D stimulation

scientific article published on 5 June 2006

Differential agonist-induced regulation of human M2 and M3 muscarinic receptors

scientific article published on December 2003

Dipeptidyl peptidase IV inhibitors in diabetes: more than inhibition of glucagon-like peptide-1 metabolism?

scientific article published in May 2008

Do overactive bladder symptoms and their treatment-associated changes exhibit a normal distribution? Implications for analysis and reporting

scientific article published on 16 January 2020

Do review articles boost journal impact factors? A longitudinal analysis for five pharmacology journals

scientific article published on 21 June 2018

Do β-adrenoceptor agonists induce homologous or heterologous desensitization in rat urinary bladder?

scientific article published on 10 November 2013

Do β3-adrenoceptor agonists cause urinary bladder smooth muscle relaxation by inhibiting acetylcholine release?

scientific article published on 17 May 2017

Does concomitant stress incontinence alter the efficacy of tolterodine in patients with overactive bladder?

scientific article published on August 2004

Does cyclic AMP mediate rat urinary bladder relaxation by isoproterenol?

scientific article published on 2 December 2004

Does gender or age affect the efficacy and safety of tolterodine?

scientific article published in September 2002

Drug-induced urinary incontinence

scientific article published on January 2008

EAU guidelines on the treatment and follow-up of non-neurogenic male lower urinary tract symptoms including benign prostatic obstruction

scientific article

Effects of ageing on muscarinic receptor subtypes and function in rat urinary bladder

scientific article published on 30 July 2005

Effects of gender, age and hypertension on beta-adrenergic receptor function in rat urinary bladder

scientific article published on 31 May 2006

Efficacy of fesoterodine over 24 hours in subjects with overactive bladder

scientific article published in April 2010

Efficacy of propiverine ER with or without α-blockers related to maximum urinary flow rate in adult men with OAB: results of a 12-week, multicenter, non-interventional study

scientific article

Emerging country pharmacology: a 10-year perspective from Naunyn-Schmiedeberg's Archives of Pharmacology

scientific article

Epac and the cardiovascular system

scientific article published on 2 February 2007

Evidence why paroxetine dose escalation is not effective in major depressive disorder: a randomized controlled trial with assessment of serotonin transporter occupancy

scientific article published in October 2008

Ex Vivo Characterization of a Novel Iodine-123-Labelled Aminomethylchroman as a Potential Agonist Ligand for SPECT Imaging of Dopamine D2/3 Receptors

scientific article

Expectations and satisfaction of academic investigators in nonclinical collaboration with the pharmaceutical industry

scientific article published on 28 February 2015

Expression and Signaling of β-Adrenoceptor Subtypes in the Diabetic Heart

scientific article published on 26 November 2020

Expression profiling of G-protein-coupled receptors in human urothelium and related cell lines

scientific article published on 3 May 2012

Extracts from Rhois aromatica and Solidaginis virgaurea inhibit rat and human bladder contraction

scientific article published on 13 February 2004

Factors associated with efficacy of an ibuprofen/pseudoephedrine combination drug in pharmacy customers with common cold symptoms

scientific article published on 07 December 2016

Flexible‐Dose Fesoterodine in Elderly Adults with Overactive Bladder: Results of the Randomized, Double‐Blind, Placebo‐Controlled Study of Fesoterodine in an Aging Population Trial ⬇️

scientific article published on January 25, 2013

Functional investigation of β-adrenoceptors in human isolated detrusor focusing on the novel selective β3-adrenoceptor agonist KUC-7322.

scientific article published on 29 May 2012

Gender comparison of muscarinic receptor expression and function in rat and human urinary bladder: differential regulation of M2 and M3 receptors?

scientific article published on 28 March 2003

How Can 1 + 1 = 3? β2-Adrenergic and Glucocorticoid Receptor Agonist Synergism in Obstructive Airway Diseases: Fig. 1 ⬇️

scientific article published on September 13, 2011

How much potential for transient receptor potential channels in the bladder?

scientific article published on 01 March 2015

How reliable are G-protein-coupled receptor antibodies?

scientific article published on 27 January 2009

How significant are your data? The need for a culture shift

scientific article

How valid are animal models to evaluate treatments for pulmonary hypertension?

scientific article published on September 2006

In vivo studies on the effects of alpha1-adrenoceptor antagonists on pupil diameter and urethral tone in rabbits

scientific article published on 18 February 2006

Indomethacin differentiates the renal effects of sphingosine-1-phosphate and sphingosylphosphorylcholine

scientific article published on 7 March 2006

Is Dipstick Urinalysis Screening Beneficial in Men with Lower Urinary Tract Symptoms?

scientific article published on 07 August 2019

Is the use of parasympathomimetics for treating an underactive urinary bladder evidence-based?

scientific article published on 16 March 2007

Lack of evidence that nebivolol is a β₃-adrenoceptor agonist

scientific article

Lack of specificity of commercially available antisera against muscarinergic and adrenergic receptors

scientific article

Long-term safety, tolerability and efficacy of flexible-dose fesoterodine in elderly patients with overactive bladder: open-label extension of the SOFIA trial

scientific article published on 4 March 2013

Longitudinal trends and subgroup analysis in publication patterns for preclinical data of newly approved drugs

scientific article

Lower Urinary Tract Symptoms: What's New in Medical Treatment?

scientific article published on 14 April 2018

Managing the progression of lower urinary tract symptoms/benign prostatic hyperplasia: therapeutic options for the man at risk

scientific article published on August 2007

Mirabegron in overactive bladder: a review of efficacy, safety, and tolerability

scientific article published on 11 October 2013

Muscarinic receptor antagonists for overactive bladder treatment: does one fit all?

scientific article published on January 2009

Muscarinic receptor expression and receptor-mediated detrusor contraction: comparison of juvenile and adult porcine tissue

scientific article published on 21 December 2007

Muscarinic receptor subtype mRNA expression in the human prostate: association with age, pathological diagnosis, prostate size, or potentially interfering medications?

scientific article published on 6 November 2013

Muscarinic receptor subtypes and signalling involved in the attenuation of isoprenaline-induced rat urinary bladder relaxation ⬇️

scientific article published on September 24, 2011

Muscarinic type-1 receptors contribute to IK,ACh in human atrial cardiomyocytes and are upregulated in patients with chronic atrial fibrillation

scientific article published on 22 December 2017

Nerve growth factor in bladder dysfunction: Contributing factor, biomarker, and therapeutic target ⬇️

scientific article published on April 21, 2011

New Author Guidelines for Displaying Data and Reporting Data Analysis and Statistical Methods in Experimental Biology

scientific article published on 01 January 2020

New Author Guidelines for Displaying Data and Reporting Data Analysis and Statistical Methods in Experimental Biology

New Author Guidelines for Displaying Data and Reporting Data Analysis and Statistical Methods in Experimental Biology

Normalization of organ bath contraction data for tissue specimen size: does one approach fit all?

scientific article published on 11 September 2019

Pharmacogenetics of hypertension treatment: a structured review

scientific article published on December 2003

Pharmacologic treatment of male stress urinary incontinence: systematic review of the literature and levels of evidence

scientific article published on October 2007

Pharmacological profile of β3-adrenoceptor agonists in clinical development for the treatment of overactive bladder syndrome ⬇️

scientific article published on December 21, 2012

Pharmacological treatment of overactive bladder: report from the International Consultation on Incontinence

scientific article published on July 2009

Pitfalls in the normalization of real-time polymerase chain reaction data

scientific article

Preclinical research strategies for newly approved drugs as reflected in early publication patterns

scientific article

Prejunctional and peripheral effects of the cannabinoid CB(1) receptor inverse agonist rimonabant (SR 141716).

scientific article published on 25 July 2008

Problem- vs. lecture-based pharmacology teaching in a German medical school

scientific article

Protocol for a systematic review of guidelines for rigour in the design, conduct and analysis of biomedical experiments involving laboratory animals

Rat β₃-adrenoceptor protein expression: antibody validation and distribution in rat gastrointestinal and urogenital tissues

scientific article published on 30 August 2014

Regulation of G protein-coupled receptor signalling: focus on the cardiovascular system and regulator of G protein signalling proteins

scientific article published on 15 March 2008

Role of muscarinic receptor antagonists in urgency and nocturia

scientific article

Role of transforming growth factor beta in rat bladder smooth muscle cell proliferation.

scientific article

S1P receptor signalling and RGS proteins; expression and function in vascular smooth muscle cells and transfected CHO cells

scientific article published on 7 October 2008

Safety and tolerability of β3-adrenoceptor agonists in the treatment of overactive bladder syndrome - insight from transcriptosome and experimental studies.

scientific article published on 8 March 2016

Selectivity of pharmacological tools: implications for use in cell physiology. A review in the theme: Cell signaling: proteins, pathways and mechanisms.

scientific article

Serotonin transporter gene promoter polymorphisms modify the association between paroxetine serotonin transporter occupancy and clinical response in major depressive disorder

scientific article

Signal Transduction Underlying Carbachol-Induced Contraction of Rat Urinary Bladder. II. Protein Kinases ⬇️

scientific article published on October 7, 2003

Signal transduction underlying carbachol-induced contraction of human urinary bladder

scientific article published on 9 February 2004

Signal transduction underlying the control of urinary bladder smooth muscle tone by muscarinic receptors and beta-adrenoceptors

scientific article published on 4 December 2007

Similarities and differences in the autonomic control of airway and urinary bladder smooth muscle

scientific article published on 12 June 2008

Small and intermediate conductance Ca(2+)-activated K+ channels confer distinctive patterns of distribution in human tissues and differential cellular localisation in the colon and corpus cavernosum

scientific article

Specificity evaluation of antibodies against human β3-adrenoceptors ⬇️

scientific article published on June 12, 2012

Sphingosine kinase-dependent activation of endothelial nitric oxide synthase by angiotensin II.

scientific article published on 20 July 2006

Sphingosine-1-phosphate regulates RGS2 and RGS16 mRNA expression in vascular smooth muscle cells

scientific article published on 21 January 2009

Sphingosylphosphorylcholine, a naturally occurring lipid mediator, inhibits human platelet function

scientific article published in February 2003

Statistical inference in abstracts of 3 influential clinical pharmacology journals analysed using a text‐mining algorithm

scientific article published in 2021

Successful pharmacologic treatment of major depressive disorder attenuates amygdala activation to negative facial expressions: a functional magnetic resonance imaging study

scientific article published on 09 August 2011

Synthesis and characterization of a novel series of agonist compounds as potential radiopharmaceuticals for imaging dopamine D₂/₃ receptors in their high-affinity state

scientific article published on 2 January 2014

Synthesis and evaluation in rats of homologous series of [(18)F]-labeled dopamine D 2/3 receptor agonists based on the 2-aminomethylchroman scaffold as potential PET tracers

scientific article published on 25 July 2015

Synthesis and evaluation in rats of the dopamine D2/3 receptor agonist 18F-AMC20 as a potential radioligand for PET.

scientific article published on 4 December 2014

The Effect of Elective Sham Dose Escalation on the Placebo Response During an Antimuscarinic Trial for Overactive Bladder Symptoms ⬇️

scientific article published on March 15, 2012

The effect of bladder outlet obstruction on alpha1- and beta-adrenoceptor expression and function.

scientific article published in January 2009

The muscarinic receptor antagonist propiverine exhibits α1-adrenoceptor antagonism in human prostate and porcine trigonum ⬇️

scientific article published on February 19, 2011

The odd sibling: features of β3-adrenoceptor pharmacology

scientific article published on 02 June 2014

The pharmacological rationale for combining muscarinic receptor antagonists and β-adrenoceptor agonists in the treatment of airway and bladder disease

scientific article

Tissue functions mediated by beta(3)-adrenoceptors-findings and challenges

scientific article published on 3 June 2010

Tools to study beta3-adrenoceptors

scientific article published on 9 January 2007

Transient receptor potential vanilloid 1 mediates nerve growth factor‐induced bladder hyperactivity and noxious input ⬇️

scientific article published on April 30, 2012

Transient relaxation of rat mesenteric microvessels by ceramides

scientific article published on January 2002

Treatment of lower urinary tract symptoms suggestive of benign prostatic hyperplasia: the cardiovascular system

scientific article

Upregulation of β3-adrenoceptors-a general marker of and protective mechanism against hypoxia?

scientific article published on 18 December 2019

Validation of a rapid, non-radioactive method to quantify internalisation of G-protein coupled receptors

scientific article published on 12 May 2007

What do we really know about benign prostatic hyperplasia and lower urinary tract symptoms in adult men?

scientific article published on 26 February 2011

cAMP-independent relaxation of smooth muscle cells via Gs-coupled receptors

scientific article

β-Adrenoceptor-mediated Relaxation of Urinary Bladder Muscle in β2-Adrenoceptor Knockout Mice

scientific article published on 9 May 2016

β3 -Adrenoceptors in the normal and diseased urinary bladder-What are the open questions?

scientific article published on 03 May 2019

β3-Adrenoceptor-mediated relaxation of rat and human urinary bladder: roles of BKCa channels and Rho kinase

scientific article published on 9 May 2015

Paulina is supported by:

About Paulina

Help