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List of works by Stephanie Bleicken

A new perspective on membrane-embedded Bax oligomers using DEER and bioresistant orthogonal spin labels

scientific article published on 10 September 2019

Automated analysis of giant unilamellar vesicles using circular Hough transformation.

scientific article published on 18 February 2014

Bax monomers form dimer units in the membrane that further self-assemble into multiple oligomeric species

scientific article

Bcl-2 proteins: Unraveling the details of a complex and dynamic network.

scientific article published on 30 October 2017

Conformational changes and protein stability of the pro-apoptotic protein Bax.

scientific article published on February 2009

Dynamic interaction of cBid with detergents, liposomes and mitochondria.

scientific article

Formation of disulfide bridges drives oligomerization, membrane pore formation, and translocation of fibroblast growth factor 2 to cell surfaces.

scientific article published on 18 February 2015

Mechanistic differences in the membrane activity of Bax and Bcl-xL correlate with their opposing roles in apoptosis.

scientific article published on January 2013

Molecular details of Bax activation, oligomerization, and membrane insertion.

scientific article published on 12 December 2009

New biophysical methods to study the membrane activity of Bcl-2 proteins.

scientific article

New limits of sensitivity of site-directed spin labeling electron paramagnetic resonance for membrane proteins.

scientific article published on 13 December 2017

Phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2)-dependent oligomerization of fibroblast growth factor 2 (FGF2) triggers the formation of a lipidic membrane pore implicated in unconventional secretion.

scientific article

Proapoptotic Bax and Bak proteins form stable protein-permeable pores of tunable size

scientific article published on 7 October 2013

Pushing the size limit of de novo structure ensemble prediction guided by sparse SDSL-EPR restraints to 200 residues: The monomeric and homodimeric forms of BAX

scientific article

Quantitative interactome of a membrane Bcl-2 network identifies a hierarchy of complexes for apoptosis regulation.

scientific article published on 13 July 2017

Structural model of active Bax at the membrane.

scientific article published on 30 October 2014

The membrane activity of BOK involves formation of large, stable toroidal pores and is promoted by cBID.

scientific article published on 8 January 2017

Topology of active, membrane-embedded Bax in the context of a toroidal pore

scientific article published on 05 September 2018

cBid, Bax and Bcl-xL exhibit opposite membrane remodeling activities.

scientific article published on 25 February 2016

gem-Diethyl Pyrroline Nitroxide Spin Labels: Synthesis, EPR Characterization, Rotamer Libraries and Biocompatibility

scientific article published on 14 May 2019