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List of works by Andrea Mancini

ATPS-72A NOVEL CXCR4 ANTAGONIST COMBINES SYNERGISTICALLY WITH BEVACIZUMAB AND SUNITINIB TO INHIBIT PROGRESSION OF GLIOBLASTOMA.

scientific article

Antitumor effects of saffron-derived carotenoids in prostate cancer cell models

scientific article published on 11 May 2014

CXCR4 pharmacogical inhibition reduces bone and soft tissue metastatic burden by affecting tumor growth and tumorigenic potential in prostate cancer preclinical models.

scientific article published on 12 June 2015

Correction to: The first-in-class alkylating deacetylase inhibitor molecule tinostamustine shows antitumor effects and is synergistic with radiotherapy in preclinical models of glioblastoma.

scientific article published on 14 March 2018

Crocetin, a Carotenoid Derived from Saffron (Crocus sativus L.), Improves Acetylcholine-Induced Vascular Relaxation in Hypertension

scientific article published on 20 December 2014

Crocus sativus stigma extract and its major constituent crocin possess significant antiproliferative properties against human prostate cancer.

scientific article published on January 2013

Dual PI3K/mTOR inhibitor, XL765 (SAR245409), shows superior effects to sole PI3K [XL147 (SAR245408)] or mTOR [rapamycin] inhibition in prostate cancer cell models.

scientific article published on 29 July 2015

Dual PI3 K/mTOR inhibition reduces prostate cancer bone engraftment altering tumor-induced bone remodeling.

scientific article published in April 2018

Effects of Crocetin Esters and Crocetin from Crocus sativus L. on Aortic Contractility in Rat Genetic Hypertension.

scientific article published on 22 September 2015

Enhancement of radiosensitivity by the novel anticancer quinolone derivative vosaroxin in preclinical glioblastoma models.

scientific article

Increased expression and activity of p75NTR are crucial events in azacitidine-induced cell death in prostate cancer.

scientific article published on 23 May 2016

Increased levels of DNA methyltransferases are associated with the tumorigenic capacity of prostate cancer cells

scientific article published on 18 December 2012

KPT-330, a potent and selective exportin-1 (XPO-1) inhibitor, shows antitumor effects modulating the expression of cyclin D1 and survivin [corrected] in prostate cancer models.

scientific article published in December 2015

PXD101 potentiates hormonal therapy and prevents the onset of castration-resistant phenotype modulating androgen receptor, HSP90, and CRM1 in preclinical models of prostate cancer

scientific article published on 21 May 2013

Pharmacological treatment with inhibitors of nuclear export enhances the antitumor activity of docetaxel in human prostate cancer.

scientific article published on 30 November 2017

Prodrugs of Pyrazolo[3,4-d]pyrimidines: From Library Synthesis to Evaluation as Potential Anticancer Agents in an Orthotopic Glioblastoma Model.

scientific article

The brain-penetrating CXCR4 antagonist, PRX177561, increases the antitumor effects of bevacizumab and sunitinib in preclinical models of human glioblastoma

scientific article published on 05 January 2017

The first-in-class alkylating deacetylase inhibitor molecule tinostamustine shows antitumor effects and is synergistic with radiotherapy in preclinical models of glioblastoma.

scientific article published on 27 February 2018

The novel CXCR4 antagonist, PRX177561, reduces tumor cell proliferation and accelerates cancer stem cell differentiation in glioblastoma preclinical models.

scientific article

Trifluoroibuprofen inhibits α-methylacyl coenzyme A racemase (AMACR/P504S), reduces cancer cell proliferation and inhibits in vivo tumor growth in aggressive prostate cancer models.

scientific article published on January 2014

XPO1/CRM1-selective inhibitors of nuclear export (SINE) reduce tumor spreading and improve overall survival in preclinical models of prostate cancer (PCa).

scientific article published on 5 October 2014