List of works - Francesco Costanzo

A Common Mechanism Underlying the E1A Repression and the cAMP Stimulation of the H Ferritin Transcription ⬇️

scientific article published in Journal of Biological Chemistry

A novel Q3034R BRCA2 germline mutation identified in a fallopian tube cancer patient.

scientific article

A novel missense germline mutation in exon 2 of the hMSH2 gene in a HNPCC family from Southern Italy

article

A proteomics approach to identify changes in protein profiles in serum of Familial Adenomatous Polyposis patients

scientific article published on 29 July 2008

A proteomics-driven assay defines specific plasma protein signatures in different stages of Ménière's disease.

scientific article published in June 2014

An alternative model of H ferritin promoter transactivation by c-Jun

scientific article

Assessment of an ad hoc procedure for isolation and characterization of human albuminome

scientific article published on 30 June 2011

BRCA1 5083del19 mutant allele selectively up-regulates periostin expression in vitro and in vivo.

scientific article

BRCA1 expression modulates chemosensitivity of BRCA1-defective HCC1937 human breast cancer cells

scientific article published on April 2003

BRCA1 is required for hMLH1 stabilization following doxorubicin-induced DNA damage

scientific article published on 16 August 2011

Betamyosin mutations and phenotypic heterogeneity in hypertrophic cardiomyopathy

scientific article published on 11 July 2005

Bilateral cataract in a subject carrying a C to A transition in the L ferritin promoter region.

scientific article published on 27 February 2009

Biomarker discovery by plasma proteomics in familial Brugada Syndrome.

scientific article published in January 2013

Caffeine Positively Modulates Ferritin Heavy Chain Expression in H460 Cells: Effects on Cell Proliferation.

scientific article

Cardiac and skeletal muscle expression of mutant β-myosin heavy chains, degree of functional impairment and phenotypic heterogeneity in hypertrophic cardiomyopathy

scientific article published on 01 October 2012

Cloning and sequencing of a full length cDNA coding for human retinol-binding protein ⬇️

scientific article published on November 25, 1983

Cloning of the gene coding for human L apoferritin

scientific article

Co-existence of frataxin and cardiac troponin T gene mutations in a child with Friedreich Ataxia and familial hypertrophic cardiomyopathy

scientific article published on 01 March 2002

Common and interchangeable elements in the promoters of genes transcribed by RNA polymerase III

article

Corrigendum to 'specific changes in the proteomic pattern produced by the BRCA1-Ser1841Asn missense mutation' [International Journal of Biochemistry and Cell Biology (2007) 220-226].

scientific article published on 25 March 2017

DJ-1 in Endometrial Cancer

scientific article published on 01 May 2014

DJ-1 is a reliable serum biomarker for discriminating high-risk endometrial cancer.

scientific article published in June 2017

Detection of microsatellite instability and loss of heterozygosity in serum DNA of small and non-small cell lung cancer patients: a tool for early diagnosis?

scientific article published on 01 December 2000

Early effects of a hypocaloric, Mediterranean diet on laboratory parameters in obese individuals

scientific article published on 04 March 2014

Effects of glucocorticoids on activation of c-jun N-terminal, extracellular signal-regulated, and p38 MAP kinases in human pulmonary endothelial cells

scientific article published on 01 December 2001

Effects of transforming growth factor-[beta] and budesonide on mitogen-activated protein kinase activation and apoptosis in airway epithelial cells.

scientific article published on 10 January 2003

Endothelin-1 induces proliferation of human lung fibroblasts and IL-11 secretion through an ET(A) receptor-dependent activation of MAP kinases

scientific article published on 01 November 2005

Epithelial-to-mesenchymal transition in FHC-silenced cells: the role of CXCR4/CXCL12 axis.

scientific article published on 03 August 2017

Evaluating the inappropriateness of repeated laboratory testing in a teaching hospital of South Italy.

scientific article published in March 2014

Evidence of a founder mutation of BRCA1 in a highly homogeneous population from southern Italy with breast/ovarian cancer.

scientific article

Expression of genes of ferritin subunits in human hepatoma cell lines.

scientific article published in June 1989

FTH1P3, a Novel H-Ferritin Pseudogene Transcriptionally Active, Is Ubiquitously Expressed and Regulated during Cell Differentiation

scientific article

Ferritin Heavy Subunit Silencing Blocks the Erythroid Commitment of K562 Cells via miR-150 up-Regulation and GATA-1 Repression

scientific article

Ferritin heavy chain is a negative regulator of ovarian cancer stem cell expansion and epithelial to mesenchymal transition.

scientific article published on 22 August 2016

Functional analysis of MLH1 mutations linked to hereditary nonpolyposis colon cancer

scientific article published on 01 February 2002

H ferritin gene silencing in a human metastatic melanoma cell line: a proteomic analysis.

scientific article

H ferritin silencing induces protein misfolding in K562 cells: A Raman analysis

scientific article published on 7 October 2015

H-ferritin-regulated microRNAs modulate gene expression in K562 cells

scientific article published on 27 March 2015

Hereditary nonpolyposis coloretal cancer: identification of novel germline mutations in two kindreds not fulfulling the Amsterdam criteria. Mutations in brief no. 203. Online

scientific article published on 01 January 1998

High prevalence of polymorphism and low activity of thiopurine methyltransferase in patients with inflammatory bowel disease

scientific article published on 5 January 2012

Human haematological and epithelial tumor-derived cell lines express distinct patterns of onco-microRNAs

scientific article published on 30 November 2017

Identification of H ferritin-dependent and independent genes in K562 differentiating cells by targeted gene silencing and expression profiling.

scientific article published on 14 November 2013

Inhibition by anti-HLA class I mAb of IL-2 and IL-2 receptor synthesis in lymphocytes stimulated with PHA-P

scientific article published on 01 April 1990

Lack of a role of monocytes in the inhibition by monoclonal antibodies to monomorphic and polymorphic determinants of HLA class I antigens of PHA-P-induced peripheral blood mononuclear cell proliferation

scientific article published on 01 August 1989

Negative transcriptional regulation of the human periostin gene by YingYang-1 transcription factor

article

Nucleotide sequence of a mouse tRNA gene cluster.

scientific article

Okadaic Acid Stimulates H Ferritin Transcription in HeLa Cells by Increasing the Interaction between the p300 CO-Activator Molecule and the Transcription Factor Bbf

scientific article published on 01 November 1997

Plasma Proteomic Profiling in Hereditary Breast Cancer Reveals a BRCA1-Specific Signature: Diagnostic and Functional Implications

scientific article published on 10 June 2015

Polymorphic repeat length in the AIB1 gene and breast cancer risk in BRCA1 and BRCA2 mutation carriers: a meta-analysis of observational studies.

scientific article

Postmenopausal women with carotid atherosclerosis: Potential role of the serum calcium levels

scientific article published on 07 March 2013

Promoter for the human ferritin heavy chain-encoding gene (FERH): structural and functional characterization

scientific article published on 01 February 1992

Proteomics Analysis to Assess the Role of Mitochondria in BRCA1-Mediated Breast Tumorigenesis.

scientific article published on 27 March 2018

Pulsatile perfusion with intra-aortic balloon pumping ameliorates whole body response to cardiopulmonary bypass in the elderly.

scientific article published in March 2009

Role of serum ferritin level on overall survival in patients with myelodysplastic syndromes: Results of a meta-analysis of observational studies

scientific article

Sequence of human haptoglobin cDNA: evidence that the α and β subunits are coded by the same mRNA ⬇️

scientific article published on September 10, 1983

Serum Calcium Increase Correlates With Worsening of Lipid Profile: An Observational Study on a Large Cohort From South Italy

scientific article published on February 2016

Stretches of alternating poly(T-dG), with the capacity to form Z-DNA, are present in human liver transcripts.

scientific article published on May 1983

The transcriptional efficiency of clustered tRNA genes is affected by their position within the cluster

scientific article published on 01 December 1987

Tissue expression and serum levels of periostin during pregnancy: a new biomarker of embryo-endometrial cross talk at implantation.

scientific article published on 28 December 2013

Transcriptional regulation of the mismatch repair gene hMLH1

article

shRNA targeting of ferritin heavy chain activates H19/miR-675 axis in K562 cells

scientific article published on 12 March 2018

List of works by Francesco Costanzo

A Common Mechanism Underlying the E1A Repression and the cAMP Stimulation of the H Ferritin Transcription ⬇️

A novel Q3034R BRCA2 germline mutation identified in a fallopian tube cancer patient.

A novel missense germline mutation in exon 2 of the hMSH2 gene in a HNPCC family from Southern Italy

A proteomics approach to identify changes in protein profiles in serum of Familial Adenomatous Polyposis patients

A proteomics-driven assay defines specific plasma protein signatures in different stages of Ménière's disease.

An alternative model of H ferritin promoter transactivation by c-Jun

Assessment of an ad hoc procedure for isolation and characterization of human albuminome

BRCA1 5083del19 mutant allele selectively up-regulates periostin expression in vitro and in vivo.

BRCA1 expression modulates chemosensitivity of BRCA1-defective HCC1937 human breast cancer cells

BRCA1 is required for hMLH1 stabilization following doxorubicin-induced DNA damage

Betamyosin mutations and phenotypic heterogeneity in hypertrophic cardiomyopathy

Bilateral cataract in a subject carrying a C to A transition in the L ferritin promoter region.

Biomarker discovery by plasma proteomics in familial Brugada Syndrome.

Caffeine Positively Modulates Ferritin Heavy Chain Expression in H460 Cells: Effects on Cell Proliferation.

Cardiac and skeletal muscle expression of mutant β-myosin heavy chains, degree of functional impairment and phenotypic heterogeneity in hypertrophic cardiomyopathy

Cloning and sequencing of a full length cDNA coding for human retinol-binding protein ⬇️

Cloning of the gene coding for human L apoferritin

Co-existence of frataxin and cardiac troponin T gene mutations in a child with Friedreich Ataxia and familial hypertrophic cardiomyopathy

Common and interchangeable elements in the promoters of genes transcribed by RNA polymerase III

Corrigendum to 'specific changes in the proteomic pattern produced by the BRCA1-Ser1841Asn missense mutation' [International Journal of Biochemistry and Cell Biology (2007) 220-226].

DJ-1 in Endometrial Cancer

DJ-1 is a reliable serum biomarker for discriminating high-risk endometrial cancer.

Detection of microsatellite instability and loss of heterozygosity in serum DNA of small and non-small cell lung cancer patients: a tool for early diagnosis?

Early effects of a hypocaloric, Mediterranean diet on laboratory parameters in obese individuals

Effects of glucocorticoids on activation of c-jun N-terminal, extracellular signal-regulated, and p38 MAP kinases in human pulmonary endothelial cells

Effects of transforming growth factor-[beta] and budesonide on mitogen-activated protein kinase activation and apoptosis in airway epithelial cells.

Endothelin-1 induces proliferation of human lung fibroblasts and IL-11 secretion through an ET(A) receptor-dependent activation of MAP kinases

Epithelial-to-mesenchymal transition in FHC-silenced cells: the role of CXCR4/CXCL12 axis.

Evaluating the inappropriateness of repeated laboratory testing in a teaching hospital of South Italy.

Evidence of a founder mutation of BRCA1 in a highly homogeneous population from southern Italy with breast/ovarian cancer.

Expression of genes of ferritin subunits in human hepatoma cell lines.

FTH1P3, a Novel H-Ferritin Pseudogene Transcriptionally Active, Is Ubiquitously Expressed and Regulated during Cell Differentiation

Ferritin Heavy Subunit Silencing Blocks the Erythroid Commitment of K562 Cells via miR-150 up-Regulation and GATA-1 Repression

Ferritin heavy chain is a negative regulator of ovarian cancer stem cell expansion and epithelial to mesenchymal transition.

Functional analysis of MLH1 mutations linked to hereditary nonpolyposis colon cancer

H ferritin gene silencing in a human metastatic melanoma cell line: a proteomic analysis.

H ferritin silencing induces protein misfolding in K562 cells: A Raman analysis

H-ferritin-regulated microRNAs modulate gene expression in K562 cells

Hereditary nonpolyposis coloretal cancer: identification of novel germline mutations in two kindreds not fulfulling the Amsterdam criteria. Mutations in brief no. 203. Online

High prevalence of polymorphism and low activity of thiopurine methyltransferase in patients with inflammatory bowel disease

Human haematological and epithelial tumor-derived cell lines express distinct patterns of onco-microRNAs

Identification of H ferritin-dependent and independent genes in K562 differentiating cells by targeted gene silencing and expression profiling.

Inhibition by anti-HLA class I mAb of IL-2 and IL-2 receptor synthesis in lymphocytes stimulated with PHA-P

Lack of a role of monocytes in the inhibition by monoclonal antibodies to monomorphic and polymorphic determinants of HLA class I antigens of PHA-P-induced peripheral blood mononuclear cell proliferation

Negative transcriptional regulation of the human periostin gene by YingYang-1 transcription factor

Nucleotide sequence of a mouse tRNA gene cluster.

Okadaic Acid Stimulates H Ferritin Transcription in HeLa Cells by Increasing the Interaction between the p300 CO-Activator Molecule and the Transcription Factor Bbf

Plasma Proteomic Profiling in Hereditary Breast Cancer Reveals a BRCA1-Specific Signature: Diagnostic and Functional Implications

Polymorphic repeat length in the AIB1 gene and breast cancer risk in BRCA1 and BRCA2 mutation carriers: a meta-analysis of observational studies.

Postmenopausal women with carotid atherosclerosis: Potential role of the serum calcium levels

Promoter for the human ferritin heavy chain-encoding gene (FERH): structural and functional characterization

Proteomics Analysis to Assess the Role of Mitochondria in BRCA1-Mediated Breast Tumorigenesis.

Pulsatile perfusion with intra-aortic balloon pumping ameliorates whole body response to cardiopulmonary bypass in the elderly.

Role of serum ferritin level on overall survival in patients with myelodysplastic syndromes: Results of a meta-analysis of observational studies

Sequence of human haptoglobin cDNA: evidence that the α and β subunits are coded by the same mRNA ⬇️

Serum Calcium Increase Correlates With Worsening of Lipid Profile: An Observational Study on a Large Cohort From South Italy

Stretches of alternating poly(T-dG), with the capacity to form Z-DNA, are present in human liver transcripts.

The transcriptional efficiency of clustered tRNA genes is affected by their position within the cluster

Tissue expression and serum levels of periostin during pregnancy: a new biomarker of embryo-endometrial cross talk at implantation.

Transcriptional regulation of the mismatch repair gene hMLH1

shRNA targeting of ferritin heavy chain activates H19/miR-675 axis in K562 cells