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List of works by Timothy J Sargeant

A 3-D in vitro co-culture model of mammary gland involution.

scientific article published on June 2014

A novel fluorescent probe reveals starvation controls the commitment of amyloid precursor protein to the lysosome.

scientific article published on 19 June 2017

Acute in utero morphine exposure slows G2/M phase transition in radial glial and basal progenitor cells in the dorsal telencephalon of the E15.5 embryonic mouse.

scientific article published on 9 September 2008

Adeno-associated virus-mediated expression of β-hexosaminidase prevents neuronal loss in the Sandhoff mouse brain ⬇️

scientific article published on August 18, 2011

Analysis of the Involuting Mouse Mammary Gland: An In Vivo Model for Cell Death

scientific article published in January 2017

Autophagy Modulation as a Treatment of Amyloid Diseases

scientific article published on 16 September 2019

Characterization of inducible models of Tay-Sachs and related disease

scientific article (publication date: September 2012)

Commentary: Possible involvement of lysosomal dysfunction in pathological changes of the brain in aged progranulin-deficient mice

scientific article published on 3 February 2016

Endo-lysosomal and autophagic dysfunction: a driving factor in Alzheimer's disease?

scientific article published on 27 December 2016

Genetic variation within endolysosomal system is associated with late-onset Alzheimer's disease

scientific article published on 01 September 2018

Immunocytochemical Evidence for Golgi Vesicle Involvement in Milk Fat Globule Secretion.

scientific article published on 15 September 2015

Lysosomal Dysregulation in the Murine AppNL-G-F/NL-G-F Model of Alzheimer's Disease

scientific article published on 07 January 2020

Lysosomal LAMP1 immunoreactivity exists in both diffuse and neuritic amyloid plaques in the human hippocampus.

scientific article published on 2 April 2018

Measurement of autophagic flux in humans: an optimized method for blood samples

scientific article published on 08 November 2020

Mu opioid receptors are expressed on radial glia but not migrating neuroblasts in the late embryonic mouse brain.

scientific article

Opioidergic regulation of astroglial/neuronal proliferation: where are we now?

scientific article published on 11 September 2008

Rapamycin and Alzheimer disease: a double-edged sword?

scientific article published on 22 May 2019

Rapamycin and Alzheimer disease: a hypothesis for the effective use of rapamycin for treatment of neurodegenerative disease

scientific article published in 2023

Reduction in open field activity in the absence of memory deficits in the AppNL-G-F knock-in mouse model of Alzheimer's disease

scientific article published on 5 September 2017

Retromer has a selective function in cargo sorting via endosome transport carriers

scientific article published on 17 December 2018

Retromer regulates the lysosomal clearance of MAPT/tau

scientific article published on 22 September 2020

Signal transducer and activator of transcription 3 and the phosphatidylinositol 3-kinase regulatory subunits p55α and p50α regulate autophagy in vivo.

scientific article

Stat3 controls cell death during mammary gland involution by regulating uptake of milk fat globules and lysosomal membrane permeabilization

scientific article

Stat3 mediated alterations in lysosomal membrane protein composition

scientific article published on 17 January 2018

TNF, acting through inducibly expressed TNFR2, drives activation and cell cycle entry of c-Kit+ cardiac stem cells in ischemic heart disease

scientific article published on September 2013

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