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List of works by Carlos M Farinha

A comparison of 14 antibodies for the biochemical detection of the cystic fibrosis transmembrane conductance regulator protein.

scientific article

Analysis of genomic CFTR DNA.

scientific article published in August 2004

Antibodies for CFTR studies.

scientific article published in August 2004

BAG-1 stabilizes mutant F508del-CFTR in a ubiquitin-like-domain-dependent manner

scientific article published on 5 October 2012

Biochemical methods to assess CFTR expression and membrane localization

article

CFTR mutations altering CFTR fragmentation

scientific article published on January 2013

Characterization of novel airway submucosal gland cell models for cystic fibrosis studies

scientific article

Contribution of casein kinase 2 and spleen tyrosine kinase to CFTR trafficking and protein kinase A-induced activity.

scientific article

Control of cystic fibrosis transmembrane conductance regulator membrane trafficking: not just from the endoplasmic reticulum to the Golgi

scientific article

EPAC1 activation by cAMP stabilizes CFTR at the membrane by promoting its interaction with NHERF1.

scientific article published on 20 May 2016

Folding Status Is Determinant over Traffic-Competence in Defining CFTR Interactors in the Endoplasmic Reticulum.

scientific article published on 14 April 2019

From the endoplasmic reticulum to the plasma membrane: mechanisms of CFTR folding and trafficking

scientific article

Full Rescue of F508del-CFTR Processing and Function by CFTR Modulators Can Be Achieved by Removal of Two Regulatory Regions

scientific article published on 25 June 2020

Improved Fmoc-solid-phase peptide synthesis of an extracellular loop of CFTR for antibody selection by the phage display technology

scientific article published on 12 May 2020

Increased efficacy of VX-809 in different cellular systems results from an early stabilization effect of F508del-CFTR.

scientific article published on 11 June 2015

Investigating Alternative Transport of Integral Plasma Membrane Proteins from the ER to the Golgi: Lessons from the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR).

scientific article published in January 2016

LMTK2-mediated phosphorylation regulates CFTR endocytosis in human airway epithelial cells

scientific article

Measurements of Functional Responses in Human Primary Lung Cells as a Basis for Personalized Therapy for Cystic Fibrosis.

scientific article published on 17 December 2014

Mechanical Properties of Human Bronchial Epithelial Cells Expressing Wt- and Mutant CFTR

scientific article published on 21 April 2020

Methods for RNA extraction, cDNA preparation and analysis of CFTR transcripts.

scientific article published in August 2004

Most F508del-CFTR is targeted to degradation at an early folding checkpoint and independently of calnexin

scientific article

Partial rescue of F508del-CFTR channel gating with modest improvement of protein processing, but not stability by a dual-acting small molecule

scientific article published on 10 January 2018

Post-translational modifications of CFTR: insight into protein trafficking and cystic fibrosis disease.

scientific article published on 5 July 2013

Protein and lipid interactions - Modulating CFTR trafficking and rescue.

scientific article published on 5 September 2017

Proteomic interaction profiling reveals KIFC1 as a factor involved in early targeting of F508del-CFTR to degradation

scientific article published on 31 July 2018

Rab GTPases regulate the trafficking of channels and transporters - a focus on cystic fibrosis.

scientific article

Regulation of ENaC biogenesis by the stress response protein SERP1.

scientific article

Revertants, low temperature, and correctors reveal the mechanism of F508del-CFTR rescue by VX-809 and suggest multiple agents for full correction.

scientific article

Solubilizing Mutations Used to Crystallize One CFTR Domain Attenuate the Trafficking and Channel Defects Caused by the Major Cystic Fibrosis Mutation

scientific article published on 01 January 2008

Targeting of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Protein with a Technetium-99m Imaging Probe

scientific article published on 12 June 2018

Teaching biochemistry at Lisbon University-Facing the challenge of the Bologna Declaration in the 25th anniversary of the biochemistry course

scientific article published on 01 November 2007

The human DnaJ homologue (Hdj)-1/heat-shock protein (Hsp) 40 co-chaperone is required for the in vivo stabilization of the cystic fibrosis transmembrane conductance regulator by Hsp70

scientific article

Unusually common cystic fibrosis mutation in Portugal encodes a misprocessed protein.

scientific article published on November 2003