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List of works by Hans J van der Vliet

A bispecific nanobody approach to leverage the potent and widely applicable tumor cytolytic capacity of Vγ9Vδ2-T cells.

scientific article published on 20 October 2017

A functional bioassay to determine the activity of anti-VEGF antibody therapy in blood of patients with cancer.

scientific article published on 30 August 2016

A phase I study of the natural killer T-cell ligand alpha-galactosylceramide (KRN7000) in patients with solid tumors

scientific article published on 01 December 2002

A safety and immunogenicity study of immunization with hVEGF26-104/RFASE in cynomolgus monkeys

scientific article published on 05 March 2018

A space-occupying lesion of the skull base, masked by nasopharyngeal lymphatic tissue hypertrophy and causing cranial nerve dysfunction in an HIV-infected patient.

scientific article published on 23 February 2002

Activated iNKT cells promote Vγ9Vδ2-T cell anti-tumor effector functions through the production of TNF-α.

scientific article published on 4 November 2011

Aminobisphosphonates inhibit dendritic cell-mediated antigen-specific activation of CD1d-restricted iNKT cells.

scientific article

An α-galactosylceramide nose job shapes up iNKT cells

scientific article published on 01 January 2012

Attenuation of invariant natural killer T-cell anergy induction through intradermal delivery of alpha-galactosylceramide

scientific article published on 08 June 2010

Bispecific antibody platforms for cancer immunotherapy

scientific article published on 20 August 2014

Body mass index and 20-specific cancers: re-analyses of dose-response meta-analyses of observational studies

scientific article published on 28 December 2017

Breast-cancer adjuvant therapy with zoledronic acid

scientific article published on 01 January 2012

Bulldozing β-linked glycolipids for recognition by invariant NKT cells

scientific article published on 01 January 2012

CD1d-restricted antigen presentation by Vγ9Vδ2-T cells requires trogocytosis

scientific article

Case 19-2009: Carcinoma of the gastroesophageal junction

scientific article published on 01 September 2009

Circulating V(alpha24+) Vbeta11+ NKT cell numbers are decreased in a wide variety of diseases that are characterized by autoreactive tissue damage

scientific article published on 01 August 2001

Circulating Valpha24+Vbeta11+ NKT cell numbers and dendritic cell CD1d expression in hepatitis C virus infected patients.

scientific article published on February 2005

Circulating invariant natural killer T-cell numbers predict outcome in head and neck squamous cell carcinoma: updated analysis with 10-year follow-up

scientific article published on 17 January 2012

Clinical evaluation of the efficacy of methylnaltrexone in resolving constipation induced by different opioid subtypes combined with laboratory analysis of immunomodulatory and antiangiogenic effects of methylnaltrexone

scientific article

Clinical experience with α-galactosylceramide (KRN7000) in patients with advanced cancer and chronic hepatitis B/C infection.

scientific article published on 18 December 2010

Combination of NK Cells and Cetuximab to Enhance Anti-Tumor Responses in RAS Mutant Metastatic Colorectal Cancer

scientific article

Correction: Prevention of Vγ9Vδ2 T Cell Activation by a Vγ9Vδ2 TCR Nanobody

scientific article published in May 2017

Cutting edge: Rapid recovery of NKT cells upon institution of highly active antiretroviral therapy for HIV-1 infection

scientific article published on 01 November 2006

Differential effects of inhibitors of the PI3K/mTOR pathway on the expansion and functionality of regulatory T cells.

scientific article published on 14 May 2016

Effects of alpha-galactosylceramide (KRN7000), interleukin-12 and interleukin-7 on phenotype and cytokine profile of human Valpha24+ Vbeta11+ T cells

scientific article

Ex vivo analysis of resident hepatic pro-inflammatory CD1d-reactive T cells and hepatocyte surface CD1d expression in hepatitis C.

scientific article

Exploiting regulatory T-cell populations for the immunotherapy of cancer.

scientific article published on September 2007

Exploiting the CD1d-iNKT cell axis for potentiation of DC-based cancer vaccines

scientific article published on 01 January 2014

Expression of granzyme B during primary cytomegalovirus infection after renal transplantation

scientific article published on 01 March 1999

Generation and characterization of CD1d-specific single-domain antibodies with distinct functional features

scientific article

Generation of antitumor invariant natural killer T cell lines in multiple myeloma and promotion of their functions via lenalidomide: a strategy for immunotherapy.

scientific article

Gram-positive bacteria: a major microbial ‘turn-on’ for invariant NKT cells

scientific article published on 01 January 2012

Hepatitis C Virus (HCV)-Specific CD8+ Cells Produce Transforming Growth Factor That Can Suppress HCV-Specific T-Cell Responses

scientific article (publication date: June 2007)

High-efficiency lysis of cervical cancer by allogeneic NK cells derived from umbilical cord progenitors is independent of HLA status

scientific article published on 25 October 2016

Highly specific and potently activating Vγ9Vδ2-T cell specific nanobodies for diagnostic and therapeutic applications.

scientific article published on 30 June 2016

Human natural killer T cells acquire a memory-activated phenotype before birth

scientific article published on 01 April 2000

IPEX as a result of mutations in FOXP3

scientific article

Immunological effects of everolimus in patients with metastatic renal cell cancer

scientific article published in October 2017

In Vivo Efficacy of Umbilical Cord Blood Stem Cell-Derived NK Cells in the Treatment of Metastatic Colorectal Cancer

scientific article published on 06 February 2017

Invariant natural killer T cells and immunotherapy of cancer.

scientific article published on 09 September 2008

Irinotecan-induced dysarthria.

scientific article

Low levels of circulating invariant natural killer T cells predict poor clinical outcome in patients with head and neck squamous cell carcinoma

scientific article published on 01 March 2007

MUTZ-3, a human cell line model for the cytokine-induced differentiation of dendritic cells from CD34+ precursors.

scientific article published on July 2002

Mechanisms of intimate and long-distance cross-talk between glioma and myeloid cells: how to break a vicious cycle.

scientific article

Megacolon during treatment with lactulose

scientific article

Multiple pseudotumors in IgG4-associated multifocal systemic fibrosis

scientific article published on 01 December 2004

Myocardial air collections as a result of infection with a gas producing strain of Escherichia coli.

scientific article published on June 2004

Natural Killer T cells

scientific article published on 01 September 2002

Natural killer T cell-based cancer immunotherapy

scientific article published on 01 October 2006

Nuancing the proposed role of NKT cells in aging ⬇️

scientific article published on March 1, 2011

Outcomes and Treatment Options for Duodenal Adenocarcinoma: A Systematic Review and Meta-Analysis

scientific article published on 26 June 2018

Peripheral blood IFN-gamma-secreting Valpha24+Vbeta11+ NKT cell numbers are decreased in cancer patients independent of tumor type or tumor load

scientific article published on 01 August 2005

Phase I Clinical Trial to Determine the Feasibility and Maximum Tolerated Dose of Panitumumab to Standard Gemcitabine-Based Chemoradiation in Locally Advanced Pancreatic Cancer.

scientific article

Polarization of Valpha24+ Vbeta11+ natural killer T cells of healthy volunteers and cancer patients using alpha-galactosylceramide-loaded and environmentally instructed dendritic cells

scientific article published on 01 July 2003

Potent expansion of human natural killer T cells using alpha-galactosylceramide (KRN7000)-loaded monocyte-derived dendritic cells, cultured in the presence of IL-7 and IL-15

scientific article published on 01 January 2001

Preoperative chemoradiation therapy in combination with panitumumab for patients with resectable esophageal cancer: the PACT study

scientific article published in September 2014

Prevention of Vγ9Vδ2 T Cell Activation by a Vγ9Vδ2 TCR Nanobody.

scientific article published on 28 November 2016

Quantification of Bax/Bcl-2 ratios in peripheral blood lymphocytes, monocytes and granulocytes and their relation to susceptibility to anti-Fas (anti-CD95)-induced apoptosis

scientific article published on 01 November 1997

Randomized phase 2 study of gemcitabine and cisplatin with or without vitamin supplementation in patients with advanced esophagogastric cancer.

scientific article published on 25 April 2018

Response to Comment on "mTOR Inhibition Per Se Induces Nuclear Localization of FOXP3 and Conversion of Invariant NKT (iNKT) Cells into Immunosuppressive Regulatory iNKT Cells".

scientific article

Reversible posterior leukoencephalopathy syndrome during sunitinib therapy for metastatic renal cell carcinoma ⬇️

scientific article published on March 16, 2012

Schistosomiasis

scientific article published on 01 June 2005

Selective decrease in circulating V alpha 24+V beta 11+ NKT cells during HIV type 1 infection

scientific article published on 01 February 2002

Severe toxicity of capecitabine following uncomplicated treatment with 5-fluorouracil/leucovorin

scientific article published on 22 June 2010

Standardized and flexible eight colour flow cytometry panels harmonized between different laboratories to study human NK cell phenotype and function.

scientific article

Statistical controversies in clinical research: overlap and errors in the meta-analyses of microRNA genetic association studies in cancers.

scientific article

Synergistic effect of KRN7000 with interleukin-15, -7, and -2 on the expansion of human V alpha 24+V beta 11+ T cells in vitro

scientific article published on 01 April 2000

The CD8+ granzyme B+ T-cell subset in peripheral blood from healthy individuals contains activated and apoptosis-prone cells.

scientific article published in March 1998

The Rise of Allogeneic Natural Killer Cells As a Platform for Cancer Immunotherapy: Recent Innovations and Future Developments.

scientific article published on 31 May 2017

The effects of systemic treatment with aminobisphosphonates and statins on circulating Vγ9Vδ2-T cells in patients with advanced cancer

scientific article published on 16 October 2017

The immunoregulatory role of CD1d-restricted natural killer T cells in disease.

scientific article published on July 2004

Vγ9Vδ2-T cells as antigen presenting cells for iNKT cell based cancer immunotherapy.

scientific article

mTOR Inhibition Per Se Induces Nuclear Localization of FOXP3 and Conversion of Invariant NKT (iNKT) Cells into Immunosuppressive Regulatory iNKT Cells

scientific article published on 3 August 2015

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