List of works - Pirjo M Apaja

A novel fluorescent probe reveals starvation controls the commitment of amyloid precursor protein to the lysosome.

scientific article published on 19 June 2017

Chaperone-Independent Peripheral Quality Control of CFTR by RFFL E3 Ligase.

scientific article published in March 2018

Chaperones rescue the energetic landscape of mutant CFTR at single molecule and in cell.

scientific article published on 30 August 2017

Degradation mechanism of a Golgi-retained distal renal tubular acidosis mutant of the kidney anion exchanger 1 in renal cells.

scientific article

Endocytic sorting of CFTR variants monitored by single-cell fluorescence ratiometric image analysis (FRIA) in living cells.

scientific article published on January 2011

Endofin is required for HD-PTP and ESCRT-0 interdependent endosomal sorting of ubiquitinated transmembrane cargoes

scientific article published on 14 October 2021

Identification and structural characterization of the neuronal luteinizing hormone receptor associated with sensory systems

scientific journal article

Insights into MLC pathogenesis: GlialCAM is an MLC1 chaperone required for proper activation of volume-regulated anion currents.

scientific article published on 20 June 2013

Interplay of Endosomal pH and Ligand Occupancy in Integrin α5β1 Ubiquitination, Endocytic Sorting, and Cell Migration

scientific article published on 7 October 2015

Leukoencephalopathy-causing CLCN2 mutations are associated with impaired Cl- channel function and trafficking.

scientific article

Luteinizing hormone receptor ectodomain splice variant misroutes the full-length receptor into a subcompartment of the endoplasmic reticulum.

scientific article

Protein homeostasis at the plasma membrane

scientific article

Protein quality control at the plasma membrane

scientific article published on 14 May 2011

Quality control for unfolded proteins at the plasma membrane

scientific article

Ribosomal Stalk Protein Silencing Partially Corrects the ΔF508-CFTR Functional Expression Defect

scientific article

Single Cell Fluorescence Ratio Image Analysis for Studying ESCRT Function in Receptor Trafficking

scientific article published on 01 January 2019

Some gating potentiators, including VX-770, diminish ΔF508-CFTR functional expression.

scientific article published on July 2014

The endoplasmic reticulum Ca2+-pump SERCA2b interacts with G protein-coupled receptors and enhances their expression at the cell surface

scientific journal article

Ubiquitination-dependent quality control of hERG K+ channel with acquired and inherited conformational defect at the plasma membrane

scientific article published on 23 October 2013

Ubr1-induced selective endophagy/autophagy protects against the endosomal and Ca<sup>2+</sup>-induced proteostasis disease stress

scientific article published on 01 March 2022

List of works by Pirjo M Apaja

A novel fluorescent probe reveals starvation controls the commitment of amyloid precursor protein to the lysosome.

Chaperone-Independent Peripheral Quality Control of CFTR by RFFL E3 Ligase.

Chaperones rescue the energetic landscape of mutant CFTR at single molecule and in cell.

Degradation mechanism of a Golgi-retained distal renal tubular acidosis mutant of the kidney anion exchanger 1 in renal cells.

Endocytic sorting of CFTR variants monitored by single-cell fluorescence ratiometric image analysis (FRIA) in living cells.

Endofin is required for HD-PTP and ESCRT-0 interdependent endosomal sorting of ubiquitinated transmembrane cargoes

Identification and structural characterization of the neuronal luteinizing hormone receptor associated with sensory systems

Insights into MLC pathogenesis: GlialCAM is an MLC1 chaperone required for proper activation of volume-regulated anion currents.

Interplay of Endosomal pH and Ligand Occupancy in Integrin α5β1 Ubiquitination, Endocytic Sorting, and Cell Migration

Leukoencephalopathy-causing CLCN2 mutations are associated with impaired Cl- channel function and trafficking.

Luteinizing hormone receptor ectodomain splice variant misroutes the full-length receptor into a subcompartment of the endoplasmic reticulum.

Protein homeostasis at the plasma membrane

Protein quality control at the plasma membrane

Quality control for unfolded proteins at the plasma membrane

Ribosomal Stalk Protein Silencing Partially Corrects the ΔF508-CFTR Functional Expression Defect

Single Cell Fluorescence Ratio Image Analysis for Studying ESCRT Function in Receptor Trafficking

Some gating potentiators, including VX-770, diminish ΔF508-CFTR functional expression.

The endoplasmic reticulum Ca2+-pump SERCA2b interacts with G protein-coupled receptors and enhances their expression at the cell surface

Ubiquitination-dependent quality control of hERG K+ channel with acquired and inherited conformational defect at the plasma membrane

Ubr1-induced selective endophagy/autophagy protects against the endosomal and Ca<sup>2+</sup>-induced proteostasis disease stress