List of works - Mario D Galigniana

Activation of the ligand-mineralocorticoid receptor functional unit by ancient, classical, and novel ligands. Structure-activity relationship.

scientific article published on January 2004

Arabidopsis immunophilins ROF1 (AtFKBP62) and ROF2 (AtFKBP65) exhibit tissue specificity, are heat-stress induced, and bind HSP90

scientific article published on 02 November 2006

Binding of hsp90-associated immunophilins to cytoplasmic dynein: direct binding and in vivo evidence that the peptidylprolyl isomerase domain is a dynein interaction domain

scientific article published on November 2002

Comparative inhibition by hard and soft metal ions of steroid-binding capacity of renal mineralocorticoid receptor cross-linked to the 90-kDa heat-shock protein heterocomplex.

scientific article published in August 1999

Correlation between pregnanesteroid conformation, receptor affinity, and anti-natriuretic effect

scientific article published on 01 November 2002

Cyclophilin A is a mitochondrial factor that forms complexes with p23. Correlative evidence for an antiapoptotic action

scientific article published on 24 December 2020

Cyclophilin-A is bound through its peptidylprolyl isomerase domain to the cytoplasmic dynein motor protein complex.

scientific article published on 20 October 2004

Differential recruitment of tetratricorpeptide repeat domain immunophilins to the mineralocorticoid receptor influences both heat-shock protein 90-dependent retrotransport and hormone-dependent transcriptional activity.

scientific article published on 15 November 2007

Dynamic mitochondrial-nuclear redistribution of the immunophilin FKBP51 is regulated by the PKA signaling pathway to control gene expression during adipocyte differentiation

scientific article published on 07 October 2013

Evidence for NL1-independent nuclear translocation of the mineralocorticoid receptor

scientific journal article

Evidence for glucocorticoid receptor transport on microtubules by dynein.

scientific article

Evidence that the peptidylprolyl isomerase domain of the hsp90-binding immunophilin FKBP52 is involved in both dynein interaction and glucocorticoid receptor movement to the nucleus

scientific article (publication date: 4 May 2001)

FKBP51 and FKBP52 in signaling and disease

scientific article

Features of the shuttle pair 11 beta-hydroxyprogesterone-11-ketoprogesterone

scientific article published on 01 April 1997

Heme Oxygenase 1 Impairs Glucocorticoid Receptor Activity in Prostate Cancer ⬇️

scientific article published on 26 February 2019

Hsp90-binding immunophilin FKBP51 forms complexes with hTERT enhancing telomerase activity.

scientific article published on 17 May 2016

Influence of calf serum on glucocorticoid-responses of certain progesterone derivatives

scientific article published on 01 August 1998

Melatonin inhibits glucocorticoid receptor nuclear translocation in mouse thymocytes

scientific article published on 17 August 2006

Modification of an essential amino group in the mineralocorticoid receptor evidences a differential conformational change of the receptor protein upon binding of antagonists, natural agonists and the synthetic agonist 11,19-oxidoprogesterone.

scientific article published in February 2002

Molecular docking study, synthesis and biological evaluation of Schiff bases as Hsp90 inhibitors

scientific article published on 15 January 2014

NF-κB transcriptional activity is modulated by FK506-binding proteins FKBP51 and FKBP52: a role for peptidyl-prolyl isomerase activity.

scientific article

Nuclear import of the glucocorticoid receptor-hsp90 complex through the nuclear pore complex is mediated by its interaction with Nup62 and importin beta

scientific journal article

Nucleocytoplasmic shuttling of the glucocorticoid receptor is influenced by tetratricopeptide repeat-containing proteins

scientific article published on 28 May 2020

Peptidyl-Prolyl Isomerase Activity of Immunophilins Could Be the Mere Consequence of Protein Complex Organization

scientific article published on 28 May 2020

Pifithrin-alpha inhibits p53 signaling after interaction of the tumor suppressor protein with hsp90 and its nuclear translocation.

scientific article published on 15 May 2004

Progestin-induced caveolin-1 expression mediates breast cancer cell proliferation

scientific article published on 26 June 2006

Regulation of steroid hormone receptor function by the 52-kDa FK506-binding protein (FKBP52).

scientific article

Regulatory role of the 90-kDa-heat-shock protein (Hsp90) and associated factors on gene expression.

scientific article published on 03 January 2014

Retrograde transport of the glucocorticoid receptor in neurites requires dynamic assembly of complexes with the protein chaperone hsp90 and is linked to the CHIP component of the machinery for proteasomal degradation

scientific article (publication date: 7 April 2004)

Steroid Receptor Coupling Becomes Nuclear ⬇️

scientific article published on June 22, 2012

Stoichiometry, abundance, and functional significance of the hsp90/hsp70-based multiprotein chaperone machinery in reticulocyte lysate.

scientific article published on 12 June 2001

Subcellular rearrangement of hsp90-binding immunophilins accompanies neuronal differentiation and neurite outgrowth

scientific journal article

Subnuclear localization of C/EBP beta is regulated by growth hormone and dependent on MAPK

scientific journal article

System among the corticosteroids: specificity and molecular dynamics.

scientific article published on 25 May 2011

Tautomycin inhibits phosphatase-dependent transformation of the rat kidney mineralocorticoid receptor

scientific article published on 01 September 1998

The 90-kDa heat-shock protein (Hsp90)-binding immunophilin FKBP51 is a mitochondrial protein that translocates to the nucleus to protect cells against oxidative stress.

scientific article

The glucocorticoid properties of the synthetic steroid pregna-1,4-diene-11beta-ol-3,20-dione (deltaHOP) are not entirely correlated with the steroid binding to the glucocorticoid receptor

scientific article published on 01 March 1999

The hsp90-FKBP52 complex links the mineralocorticoid receptor to motor proteins and persists bound to the receptor in early nuclear events. ⬇️

scientific article

The neuroregenerative mechanism mediated by the Hsp90-binding immunophilin FKBP52 resembles the early steps of neuronal differentiation.

scientific article

The p160 nuclear receptor co-activator RAC3 exerts an anti-apoptotic role through a cytoplasmatic action.

scientific article published on 29 October 2007

The role of DnaJ-like proteins in glucocorticoid receptor.hsp90 heterocomplex assembly by the reconstituted hsp90.p60.hsp70 foldosome complex.

scientific article published on March 1998

When the Cell Stress Society International became South American: meeting report of the IX International Workshop on the Molecular Biology of Stress Responses.

scientific article published on 25 September 2012

List of works by Mario D Galigniana

Activation of the ligand-mineralocorticoid receptor functional unit by ancient, classical, and novel ligands. Structure-activity relationship.

Arabidopsis immunophilins ROF1 (AtFKBP62) and ROF2 (AtFKBP65) exhibit tissue specificity, are heat-stress induced, and bind HSP90

Binding of hsp90-associated immunophilins to cytoplasmic dynein: direct binding and in vivo evidence that the peptidylprolyl isomerase domain is a dynein interaction domain

Comparative inhibition by hard and soft metal ions of steroid-binding capacity of renal mineralocorticoid receptor cross-linked to the 90-kDa heat-shock protein heterocomplex.

Correlation between pregnanesteroid conformation, receptor affinity, and anti-natriuretic effect

Cyclophilin A is a mitochondrial factor that forms complexes with p23. Correlative evidence for an antiapoptotic action

Cyclophilin-A is bound through its peptidylprolyl isomerase domain to the cytoplasmic dynein motor protein complex.

Differential recruitment of tetratricorpeptide repeat domain immunophilins to the mineralocorticoid receptor influences both heat-shock protein 90-dependent retrotransport and hormone-dependent transcriptional activity.

Dynamic mitochondrial-nuclear redistribution of the immunophilin FKBP51 is regulated by the PKA signaling pathway to control gene expression during adipocyte differentiation

Evidence for NL1-independent nuclear translocation of the mineralocorticoid receptor

Evidence for glucocorticoid receptor transport on microtubules by dynein.

Evidence that the peptidylprolyl isomerase domain of the hsp90-binding immunophilin FKBP52 is involved in both dynein interaction and glucocorticoid receptor movement to the nucleus

FKBP51 and FKBP52 in signaling and disease

Features of the shuttle pair 11 beta-hydroxyprogesterone-11-ketoprogesterone

Heme Oxygenase 1 Impairs Glucocorticoid Receptor Activity in Prostate Cancer ⬇️

Hsp90-binding immunophilin FKBP51 forms complexes with hTERT enhancing telomerase activity.

Influence of calf serum on glucocorticoid-responses of certain progesterone derivatives

Melatonin inhibits glucocorticoid receptor nuclear translocation in mouse thymocytes

Modification of an essential amino group in the mineralocorticoid receptor evidences a differential conformational change of the receptor protein upon binding of antagonists, natural agonists and the synthetic agonist 11,19-oxidoprogesterone.

Molecular docking study, synthesis and biological evaluation of Schiff bases as Hsp90 inhibitors

NF-κB transcriptional activity is modulated by FK506-binding proteins FKBP51 and FKBP52: a role for peptidyl-prolyl isomerase activity.

Nuclear import of the glucocorticoid receptor-hsp90 complex through the nuclear pore complex is mediated by its interaction with Nup62 and importin beta

Nucleocytoplasmic shuttling of the glucocorticoid receptor is influenced by tetratricopeptide repeat-containing proteins

Peptidyl-Prolyl Isomerase Activity of Immunophilins Could Be the Mere Consequence of Protein Complex Organization

Pifithrin-alpha inhibits p53 signaling after interaction of the tumor suppressor protein with hsp90 and its nuclear translocation.

Progestin-induced caveolin-1 expression mediates breast cancer cell proliferation

Regulation of steroid hormone receptor function by the 52-kDa FK506-binding protein (FKBP52).

Regulatory role of the 90-kDa-heat-shock protein (Hsp90) and associated factors on gene expression.

Retrograde transport of the glucocorticoid receptor in neurites requires dynamic assembly of complexes with the protein chaperone hsp90 and is linked to the CHIP component of the machinery for proteasomal degradation

Steroid Receptor Coupling Becomes Nuclear ⬇️

Stoichiometry, abundance, and functional significance of the hsp90/hsp70-based multiprotein chaperone machinery in reticulocyte lysate.

Subcellular rearrangement of hsp90-binding immunophilins accompanies neuronal differentiation and neurite outgrowth

Subnuclear localization of C/EBP beta is regulated by growth hormone and dependent on MAPK

System among the corticosteroids: specificity and molecular dynamics.

Tautomycin inhibits phosphatase-dependent transformation of the rat kidney mineralocorticoid receptor

The 90-kDa heat-shock protein (Hsp90)-binding immunophilin FKBP51 is a mitochondrial protein that translocates to the nucleus to protect cells against oxidative stress.

The glucocorticoid properties of the synthetic steroid pregna-1,4-diene-11beta-ol-3,20-dione (deltaHOP) are not entirely correlated with the steroid binding to the glucocorticoid receptor

The hsp90-FKBP52 complex links the mineralocorticoid receptor to motor proteins and persists bound to the receptor in early nuclear events. ⬇️

The neuroregenerative mechanism mediated by the Hsp90-binding immunophilin FKBP52 resembles the early steps of neuronal differentiation.

The p160 nuclear receptor co-activator RAC3 exerts an anti-apoptotic role through a cytoplasmatic action.

The role of DnaJ-like proteins in glucocorticoid receptor.hsp90 heterocomplex assembly by the reconstituted hsp90.p60.hsp70 foldosome complex.

When the Cell Stress Society International became South American: meeting report of the IX International Workshop on the Molecular Biology of Stress Responses.