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List of works by Alice J Sijts

A Single Residue Exchange Within a Viral CTL Epitope Alters Proteasome-Mediated Degradation Resulting in Lack of Antigen Presentation

scientific article published on 01 August 1996

Abrogation of CTL Epitope Processing by Single Amino Acid Substitution Flanking the C-Terminal Proteasome Cleavage Site

scientific article published on 01 February 2000

Amphiregulin enhances regulatory T cell-suppressive function via the epidermal growth factor receptor.

scientific article published on 17 January 2013

An Unexpected Major Role for Proteasome-Catalyzed Peptide Splicing in Generation of T Cell Epitopes: Is There Relevance for Vaccine Development?

scientific article published on 3 November 2017

Basophil-derived amphiregulin is essential for UVB irradiation-induced immune suppression.

scientific article

CCR2 Defines a Distinct Population of NK Cells and Mediates Their Migration during Influenza Virus Infection in Mice ⬇️

scientific article published on December 13, 2012

CTL epitope generation is tightly linked to cellular proteolysis of a Listeria monocytogenes antigen

scientific article published on 01 February 1996

Canonical Wnt signaling negatively modulates regulatory T cell function.

scientific article published on 15 August 2013

Conjugation of cell-penetrating peptides to parathyroid hormone affects its structure, potency, and transepithelial permeation

scientific article published on 4 March 2015

Considerations in the design of vaccines that induce CD8 T cell mediated immunity ⬇️

scientific article published on September 17, 2010

Differential influence on cytotoxic T lymphocyte epitope presentation by controlled expression of either proteasome immunosubunits or PA28

scientific article published on August 2000

Dissecting antigen processing and presentation routes in dermal vaccination strategies.

scientific article published on 24 October 2017

Efficacy Testing of H56 cDNA Tattoo Immunization against Tuberculosis in a Mouse Model

scientific article published on 11 December 2017

Efficient identification of novel HLA-A(*)0201-presented cytotoxic T lymphocyte epitopes in the widely expressed tumor antigen PRAME by proteasome-mediated digestion analysis.

scientific article published on January 2001

Enhanced inflammatory potential of CD4+ T-cells that lack proteasome immunosubunit expression, in a T-cell transfer-based colitis model

scientific article

Enhanced intracellular dissociation of major histocompatibility complex class I-associated peptides: a mechanism for optimizing the spectrum of cell surface-presented cytotoxic T lymphocyte epitopes.

scientific article published on April 1997

Epidermal Growth Factor Receptor Expression Licenses Type-2 Helper T Cells to Function in a T Cell Receptor-Independent Fashion

scientific article published on October 2017

Expression of the proteasome activator PA28 rescues the presentation of a cytotoxic T lymphocyte epitope on melanoma cells.

scientific article

Hepatitis C virus mutation affects proteasomal epitope processing

scientific article published in July 2004

Hollow microneedle-mediated intradermal delivery of model vaccine antigen-loaded PLGA nanoparticles elicits protective T cell-mediated immunity to an intracellular bacterium.

scientific article published on 13 September 2017

Identification of an H-2 Kb-presented Moloney murine leukemia virus cytotoxic T-lymphocyte epitope that displays enhanced recognition in H-2 Db mutant bm13 mice.

scientific article published on September 1994

Identification of novel avian influenza virus derived CD8+ T-cell epitopes

scientific article

Immunoproteasome-Deficiency Has No Effects on NK Cell Education, but Confers Lymphocytes into Targets for NK Cells in Infected Wild-Type Mice ⬇️

scientific article published on August 24, 2011

Induction of humoral and cellular immune responses by antigen-expressing immunostimulatory liposomes

scientific article published on 21 August 2012

Listeriolysin is processed efficiently into an MHC class I-associated epitope in Listeria monocytogenes-infected cells.

scientific article published on December 1995

MHC class I antigen processing of Listeria monocytogenes proteins: implications for dominant and subdominant CTL responses ⬇️

scientific article published on August 1, 1997

Multi-level Strategy for Identifying Proteasome-Catalyzed Spliced Epitopes Targeted by CD8+ T Cells during Bacterial Infection

scientific article

Mutational analysis of subunit i beta2 (MECL-1) demonstrates conservation of cleavage specificity between yeast and mammalian proteasomes.

scientific article published on July 1999

Nanoporous Microneedle Arrays Effectively Induce Antibody Responses against Diphtheria and Tetanus Toxoid

scientific article published on 13 December 2017

PA28 and the proteasome immunosubunits play a central and independent role in the production of MHC class I‐binding peptides in vivo ⬇️

scientific article published on March 1, 2011

Pre-existing virus-specific CD8+ T-cells provide protection against pneumovirus-induced disease in mice ⬇️

scientific article published on August 29, 2012

Protein vaccines induce uncommitted IL-2-secreting human and mouse CD4 T cells, whereas infections induce more IFN-gamma-secreting cells.

scientific article published in February 2006

Rare apolipoprotein E variant cosegregating with a unique APOE-C1-C2 haplotype in a normolipidemic family

scientific article published on 01 January 1988

Rates of Processing Determine the Immunogenicity of Immunoproteasome-Generated Epitopes

scientific article published on 01 June 2007

Stabilization of the transcription factor Foxp3 by the deubiquitinase USP7 increases Treg-cell-suppressive capacity.

scientific article

The Listeria monocytogenes-secreted p60 protein is an N-end rule substrate in the cytosol of infected cells. Implications for major histocompatibility complex class I antigen processing of bacterial proteins

scientific article published on 01 August 1997

The RTP site shared by the HIV-1 Tat protein and the 11S regulator subunit alpha is crucial for their effects on proteasome function including antigen processing

scientific article (publication date: November 2002)

The bone marrow functions as the central site of proliferation for long-lived NK cells.

scientific article

The function of the proteasome system in MHC class I antigen processing.

scientific article

The proteasome immunosubunit multicatalytic endopeptidase complex-like 1 is a T-cell-intrinsic factor influencing homeostatic expansion

scientific article

The proteasome inhibitor PI31 competes with PA28 for binding to 20S proteasomes.

scientific article published on September 1999

The role of the proteasome in the generation of MHC class I ligands and immune responses ⬇️

scientific article published on 09 March 2011

The role of the ubiquitin-proteasome pathway in MHC class I antigen processing: implications for vaccine design.

scientific article

Two Listeria monocytogenes CTL epitopes are processed from the same antigen with different efficiencies

scientific article published on 01 January 1996

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