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List of works by Binje Vick

An advanced preclinical mouse model for acute myeloid leukemia using patients' cells of various genetic subgroups and in vivo bioluminescence imaging

scientific article

Anti-leukemic effects of the V-ATPase inhibitor Archazolid A.

scientific article published on 19 October 2015

Azacitidine combined with the selective FLT3 kinase inhibitor crenolanib disrupts stromal protection and inhibits expansion of residual leukemia-initiating cells in FLT3-ITD AML with concurrent epigenetic mutations

scientific article

Bcl-x(L) and Myeloid cell leukaemia-1 contribute to apoptosis resistance of colorectal cancer cells

scientific article published in June 2008

Blockade of the PD-1/PD-L1 axis augments lysis of AML cells by the CD33/CD3 BiTE antibody construct AMG 330: reversing a T-cell-induced immune escape mechanism.

scientific article published on 4 August 2015

Dual Targeting of Acute Leukemia and Supporting Niche by CXCR4-Directed Theranostics.

scientific article published in January 2018

Endogenous TCR promotes in vivo persistence of CD19-CAR-T cells compared to a CRISPR/Cas9-mediated TCR knockout CAR

scientific article published on 01 June 2020

Frequent and reliable engraftment of certain adult primary acute lymphoblastic leukemias in mice

scientific article published on 20 September 2018

Hepatic leukemia factor is a novel leukemic stem cell regulator in DNMT3A, NPM1, and FLT3-ITD triple-mutated AML

scientific article published on 10 May 2019

In vivo inducible reverse genetics in patients' tumors to identify individual therapeutic targets

scientific article published on 27 September 2021

JMJD1C-mediated metabolic dysregulation contributes to HOXA9-dependent leukemogenesis

scientific article published on 08 January 2019

Knockout of myeloid cell leukemia-1 induces liver damage and increases apoptosis susceptibility of murine hepatocytes.

scientific article published on February 2009

Loss of KDM6A confers drug resistance in acute myeloid leukemia

scientific article published on 14 June 2019

Loss of the histone methyltransferase EZH2 induces resistance to multiple drugs in acute myeloid leukemia

scientific article published on 12 December 2016

RIG-I-based immunotherapy enhances survival in preclinical AML models and sensitizes AML cells to checkpoint blockade

scientific article published on 18 November 2019

SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4

scientific article published in Nature Communications

TRAIL-induced apoptosis of hepatocellular carcinoma cells is augmented by targeted therapies.

scientific article published on December 2009

Targeting the ER-mitochondria interface sensitizes leukemia cells towards cytostatics

scientific article published on 11 October 2018

The target landscape of clinical kinase drugs

scientific article

Tyrosine kinase inhibition increases the cell surface localization of FLT3-ITD and enhances FLT3-directed immunotherapy of acute myeloid leukemia.

scientific article published on 14 August 2017

ZBTB7A prevents RUNX1-RUNX1T1-dependent clonal expansion of human hematopoietic stem and progenitor cells

scientific article published on 02 March 2020

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