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List of works by Mark Southwood

18FDG PET Imaging can Quantify Increased Cellular Metabolism in Pulmonary Arterial Hypertension: A Proof‐of‐Principle Study ⬇️

scientific article published on October 1, 2011

A Role for miR-145 in Pulmonary Arterial Hypertension

scientific article published on 19 June 2012

A practical and efficient cellular substrate for the generation of induced pluripotent stem cells from adults: blood-derived endothelial progenitor cells

scientific article

A role for complement in the enhanced susceptibility of steatotic livers to ischemia and reperfusion injury.

scientific article published on 14 September 2009

ACTRIIA-Fc rebalances activin/GDF versus BMP signaling in pulmonary hypertension

scientific article published on 01 May 2020

Altered bone morphogenetic protein and transforming growth factor-beta signaling in rat models of pulmonary hypertension: potential for activin receptor-like kinase-5 inhibition in prevention and progression of disease

scientific article published on 19 January 2009

Angiogenesis occurs within the intimal proliferation that characterizes transplant coronary artery vasculopathy

scientific article published on 01 May 2005

BMPR-II mutations promote pulmonary arterial hypertension via a hyperinflammatory response

scientific article published on 29 May 2015

Better off blue: BMPR-2 mutation, arteriovenous malformation, and pulmonary arterial hypertension

scientific article published in June 2014

Chloroquine prevents progression of experimental pulmonary hypertension via inhibition of autophagy and lysosomal bone morphogenetic protein type II receptor degradation

scientific article published on 27 February 2013

Circulating angiogenic modulatory factors predict survival and functional class in pulmonary arterial hypertension

scientific article published on April 2013

Distinct responses to hypoxia in subpopulations of distal pulmonary artery cells contribute to pulmonary vascular remodeling in emphysema.

scientific article

Does BMPR2 Mutation Disrupt Pulmonary Vasculogenesis?

scientific article published on 01 December 2005

Dysfunctional Smad Signaling Contributes to Abnormal Smooth Muscle Cell Proliferation in Familial Pulmonary Arterial Hypertension

scientific article published on 21 April 2005

Endothelin ETA receptors predominate in chronic thromboembolic pulmonary hypertension

scientific article published on 10 February 2016

Epidermal deletion of HIF-2α stimulates wound closure

scientific article published on 13 September 2013

Evidence for the involvement of type I interferon in pulmonary arterial hypertension

scientific article published on 13 December 2013

Evidence of dysfunction of endothelial progenitors in pulmonary arterial hypertension

scientific article published on 23 July 2009

Gremlin plays a key role in the pathogenesis of pulmonary hypertension

scientific article

HIF isoforms in the skin differentially regulate systemic arterial pressure

scientific article published on 07 October 2013

Hepatic Shunting of Eggs and Pulmonary Vascular Remodeling in Bmpr2(+/-) Mice with Schistosomiasis.

scientific article published on 26 August 2015

Id proteins are critical downstream effectors of BMP signaling in human pulmonary arterial smooth muscle cells

scientific article published on 14 June 2013

Identification of novel rare sequence variation underlying heritable pulmonary arterial hypertension

Identification of rare sequence variation underlying heritable pulmonary arterial hypertension

scientific article published on 12 April 2018

Impaired Natural Killer Cell Phenotype and Function in Idiopathic and Heritable Pulmonary Arterial Hypertension

article

Investigation of Second Genetic Hits at the BMPR2 Locus as a Modulator of Disease Progression in Familial Pulmonary Arterial Hypertension

scientific article published on 01 February 2005

Neutrophil Extracellular Traps Promote Angiogenesis: Evidence From Vascular Pathology in Pulmonary Hypertension.

scientific article published on 28 July 2016

Phenotypic Characterization of EIF2AK4 Mutation Carriers in a Large Cohort of Patients Diagnosed Clinically With Pulmonary Arterial Hypertension

scientific article published on 28 September 2017

Praziquantel Reverses Pulmonary Hypertension and Vascular Remodeling in Murine Schistosomiasis

scientific article published on 15 August 2011

Proteomic analysis implicates translationally controlled tumor protein as a novel mediator of occlusive vascular remodeling in pulmonary arterial hypertension.

scientific article

Pulmonary vascular remodeling correlates with lung eggs and cytokines in murine schistosomiasis

scientific article published on 3 December 2009

Regulation of bone morphogenetic protein signalling in human pulmonary vascular development

scientific article

Selective enhancement of endothelial BMPR-II with BMP9 reverses pulmonary arterial hypertension.

scientific article published on 15 June 2015

Serotonin increases susceptibility to pulmonary hypertension in BMPR2-deficient mice

scientific article published on 23 February 2006

Smad-dependent and smad-independent induction of id1 by prostacyclin analogues inhibits proliferation of pulmonary artery smooth muscle cells in vitro and in vivo.

scientific article published on 3 June 2010

Systematic evaluation of PAXgene® tissue fixation for the histopathological and molecular study of lung cancer

scientific article published on 11 November 2019

Transcript analysis reveals a specific HOX signature associated with positional identity of human endothelial cells

scientific article

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