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List of works by Dominik Ruckerl

Alternatively activated macrophages derived from monocytes and tissue macrophages are phenotypically and functionally distinct.

scientific article

Alternatively activated macrophages express the IL-27 receptor alpha chain WSX-1

scientific article published on 05 July 2006

Characterizing Activation, Proliferation, and Ontogeny of Murine Macrophages in Parasitic Helminth Infections

scientific article published on 01 January 2018

Chitinase-like proteins promote IL-17-mediated neutrophilia in a tradeoff between nematode killing and host damage ⬇️

scientific article

DAP10 contributes to CD8+ T cell-mediated cytotoxic effector mechanisms during Mycobacterium tuberculosis infection

scientific article published on 24 September 2010

Dendritic cell-derived IL-12p40 homodimer contributes to susceptibility in cutaneous leishmaniasis in BALB/c mice

scientific article published on 01 June 2007

Enhanced monocyte recruitment and delayed alternative macrophage polarization accompanies impaired repair following myocardial infarction in C57BL/6 compared to BALB/c mice

scientific article published on 17 June 2019

IL-17 and neutrophils: unexpected players in the type 2 immune response.

scientific article published on 18 March 2015

IL-33 delivery induces serous cavity macrophage proliferation independent of interleukin-4 receptor alpha.

scientific article published on 5 September 2016

IL-4 directly signals tissue-resident macrophages to proliferate beyond homeostatic levels controlled by CSF-1

scientific article published on 07 October 2013

IL-4-producing ILC2s are required for the differentiation of TH2 cells following Heligmosomoides polygyrus infection.

scientific article published on 17 February 2016

Induction of IL-4Rα-dependent microRNAs identifies PI3K/Akt signaling as essential for IL-4-driven murine macrophage proliferation in vivo.

scientific article

Interleukin 4 promotes the development of ex-Foxp3 Th2 cells during immunity to intestinal helminths

scientific article

Local macrophage proliferation, rather than recruitment from the blood, is a signature of TH2 inflammation

scientific article

Macrophage origin limits functional plasticity in helminth-bacterial co-infection

scientific article

Macrophage proliferation, provenance, and plasticity in macroparasite infection

scientific article

Macrophages assemble! But do they need IL-4R during schistosomiasis?

scientific article published on 01 July 2019

Myeloid cell recruitment versus local proliferation differentiates susceptibility from resistance to filarial infection.

scientific article published on 4 January 2018

Oncogenic properties of apoptotic tumor cells in aggressive B cell lymphoma

scientific article published on 19 February 2015

Particles from the Echinococcus granulosus laminated layer inhibit IL-4 and growth factor-driven Akt phosphorylation and proliferative responses in macrophages

scientific article published on 14 December 2016

Purine metabolism controls innate lymphoid cell function and protects against intestinal injury.

scientific article

Reduction of tamoxifen resistance in human breast carcinomas by tamoxifen-containing liposomes in vivo.

scientific article published on August 2004

Small organic compounds enhance antigen loading of class II major histocompatibility complex proteins by targeting the polymorphic P1 pocket

scientific article

Suppressor of Cytokine Signaling 3 in Macrophages Prevents Exacerbated Interleukin-6-Dependent Arginase-1 Activity and Early Permissiveness to Experimental Tuberculosis.

scientific article published on 10 November 2017

The IL-27 receptor chain WSX-1 differentially regulates antibacterial immunity and survival during experimental tuberculosis

scientific article published on 01 March 2005

The IL-4/STAT6 signaling axis establishes a conserved microRNA signature in human and mouse macrophages regulating cell survival via miR-342-3p

scientific article

The M2 triangle: gp130 binding cytokines drive macrophages to promote tumor growth.

scientific article published on 28 February 2018

The Silent Undertakers: Macrophages Programmed for Efferocytosis.

scientific article published in November 2017

The Transcription Factor STAT6 Mediates Direct Repression of Inflammatory Enhancers and Limits Activation of Alternatively Polarized Macrophages.

scientific article

The adult murine heart has a sparse, phagocytically active macrophage population that expands through monocyte recruitment and adopts an 'M2' phenotype in response to Th2 immunologic challenge.

scientific article published on 7 February 2015

The biology of nematode- and IL4Rα-dependent murine macrophage polarization in vivo as defined by RNA-Seq and targeted lipidomics.

scientific article

The secreted triose phosphate isomerase of Brugia malayi is required to sustain microfilaria production in vivo

scientific article (publication date: February 2014)

Unconventional maturation of dendritic cells induced by particles from the laminated layer of larval Echinococcus granulosus

scientific article

Ym1 induces RELMα and rescues IL-4Rα deficiency in lung repair during nematode infection

scientific article published on 30 November 2018

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