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List of works by Sylvain Doré

A Comparison of Pathophysiology in Humans and Rodent Models of Subarachnoid Hemorrhage.

scientific article

A Pilot Study of Inhaled CO Therapy in Neonatal Hypoxia-Ischemia: Carboxyhemoglobin Concentrations and Brain Volumes.

scientific article

Age-Dependent Effects of Haptoglobin Deletion in Neurobehavioral and Anatomical Outcomes Following Traumatic Brain Injury

scientific article published on 19 July 2016

Animal Models of Posttraumatic Seizures and Epilepsy

scientific article published in January 2016

Bilirubin and Ischemic Stroke: Rendering the Current Paradigm to Better Understand the Protective Effects of Bilirubin

scientific article published on 05 January 2019

Blood-Related Toxicity after Traumatic Brain Injury: Potential Targets for Neuroprotection

scientific article published on 16 October 2019

Carbon monoxide-activated Nrf2 pathway leads to protection against permanent focal cerebral ischemia.

scientific article published on 18 August 2011

Catalytically inactive heme oxygenase-2 mutant is cytoprotective

scientific article published on 01 August 2005

Cathepsin G-dependent modulation of platelet thrombus formation in vivo by blood neutrophils

scientific article

Characterization of heme oxygenase in adult rodent platelets.

scientific article published in April 2005

Comment on the checking of nasogastric tubes by epigastric auscultation ⬇️

scientific article published on 01 January 1991

Considerations for the Optimization of Induced White Matter Injury Preclinical Models

scientific article

Contribution of PGE2 EP1 receptor in hemin-induced neurotoxicity

scientific article published on 07 October 2013

Cytosolic phospholipase A2alpha amplifies early cyclooxygenase-2 expression, oxidative stress and MAP kinase phosphorylation after cerebral ischemia in mice ⬇️

scientific article published on July 30, 2010

Death-associated protein kinase-mediated cell death modulated by interaction with DANGER

scientific journal article

Decreased activity of the antioxidant heme oxygenase enzyme: implications in ischemia and in Alzheimer’s disease1,2 1Guest Editors: Mark A. Smith and George Perry 2This article is part of a series of reviews on “Causes and Consequences of Oxidati

Deletion of the hemopexin or heme oxygenase-2 gene aggravates brain injury following stroma-free hemoglobin-induced intracerebral hemorrhage

scientific article

Detrimental role of the EP1 prostanoid receptor in blood-brain barrier damage following experimental ischemic stroke.

scientific article

Dietary flavonoids are neuroprotective through Nrf2-coordinated induction of endogenous cytoprotective proteins ⬇️

scientific article published on September 1, 2011

Distinct protective mechanisms of HO-1 and HO-2 against hydroperoxide-induced cytotoxicity.

scientific article published on January 2005

Distinctive effect of anesthetics on the effect of limb remote ischemic postconditioning following ischemic stroke

scientific article published on 16 January 2020

Distribution and levels of [125I]IGF-I, [125I]IGF-II and [125I]insulin receptor binding sites in the hippocampus of aged memory-unimpaired and -impaired rats ⬇️

scientific article published on October 1, 1997

Distribution and levels of insulin-like growth factor (IGF-I and IGF-II) and insulin receptor binding sites in the spinal cords of amyotrophic lateral sclerosis (ALS) patients.

scientific article published on September 1996

Effects of exercise during normoxia and hypoxia on the growth hormone-insulin-like growth factor I axis

scientific article published on 01 January 1995

Efficacy of Laropiprant in Minimizing Brain Injury Following Experimental Intracerebral Hemorrhage.

scientific article published on 25 August 2017

Efficacy of prophylactic flavan-3-ol in permanent focal ischemia in 12-mo-old mice.

scientific article

Elevated microsomal prostaglandin-E synthase-1 in Alzheimer's disease

scientific article

Endothelin-1-mediated vasoconstriction alters cerebral gene expression in iron homeostasis and eicosanoid metabolism

scientific article published on 16 September 2014

Enhancing effect of HT008-1 on cognitive function and quality of life in cognitively declined healthy adults: a randomized, double-blind, placebo-controlled, trial.

scientific article published in October 2008

Expression of prostaglandin E2 synthases in mouse postnatal cortical neurons.

scientific article published on August 2005

Fenoldopam preconditioning: role of heme oxygenase-1 in protecting human tubular cells and rodent kidneys against cold-hypoxic injury.

scientific article published on January 2011

GOSPEL: a neuroprotective protein that binds to GAPDH upon S-nitrosylation

scientific journal article

GPCR antagonists as an alternative to COX-2 inhibitors: a case for the PGE2 EP1 receptor

scientific article published on 25 July 2006

Genetic Deletion of PGF-FP Receptor Exacerbates Brain Injury Following Experimental Intracerebral Hemorrhage

scientific article published on 05 September 2018

Genetic deletion of the prostaglandin E2 E prostanoid receptor subtype 3 improves anatomical and functional outcomes after intracerebral hemorrhage

scientific article

Genome-Wide Association Study of Clinical Outcome After Aneurysmal Subarachnoid Haemorrhage: Protocol

scientific article

Ginkgo biloba extract neuroprotective action is dependent on heme oxygenase 1 in ischemic reperfusion brain injury.

scientific article

Ginseng: a promising neuroprotective strategy in stroke

scientific article

Haem oxygenase-1 prevents cell death by regulating cellular iron.

scientific article

Haemoglobin scavenging in intracranial bleeding: biology and clinical implications

scientific article published on 01 July 2018

Haptoglobin genotype and aneurysmal subarachnoid hemorrhage: Individual patient data analysis

scientific article published on 05 April 2019

Haptoglobin phenotype predicts the development of focal and global cerebral vasospasm and may influence outcomes after aneurysmal subarachnoid hemorrhage

scientific article

Heme oxygenase 1 is associated with ischemic preconditioning-induced protection against brain ischemia

scientific article published on 22 May 2009

Heme oxygenase 1, beneficial role in permanent ischemic stroke and in Gingko biloba (EGb 761) neuroprotection.

scientific article

Heme oxygenase 2 deficiency increases brain swelling and inflammation after intracerebral hemorrhage

scientific article

Heme oxygenase 2 is neuroprotective against intracerebral hemorrhage

scientific article

Heme oxygenase-1 exacerbates early brain injury after intracerebral haemorrhage

scientific article

Heme oxygenase-1 protects brain from acute excitotoxicity.

scientific article

Heme oxygenase-2 acts to prevent neuronal death in brain cultures and following transient cerebral ischemia

scientific article published on 01 January 2000

Heme–hemopexin complex attenuates neuronal cell death and stroke damage.

scientific article published on 2 April 2014

Histone deacetylase inhibition activates transcription factor Nrf2 and protects against cerebral ischemic damage ⬇️

scientific article published on December 17, 2011

Human osteoarthritic chondrocytes possess an increased number of insulin-like growth factor 1 binding sites but are unresponsive to its stimulation. Possible role of IGF-1-binding proteins

scientific article published on 01 February 1994

Impact of neonatal kainate treatment on hippocampal insulin-like growth factor receptors.

scientific article

Importance of normothermia control in investigating delayed neuronal injury in a mouse global ischemia model

scientific article

Increased brain hemopexin levels improve outcomes after intracerebral hemorrhage.

scientific article published on 18 November 2016

Insulin-like growth factor I protects and rescues hippocampal neurons against beta-amyloid- and human amylin-induced toxicity.

scientific article

Insulin-like growth factors-I and -II differentially regulate endogenous acetylcholine release from the rat hippocampal formation ⬇️

scientific article published on December 9, 1997

Intracerebral hemorrhage outcomes following selective blockade or stimulation of the PGE2 EP1 receptor.

scientific article published on August 2015

Korean Red Ginseng Pretreatment Protects Against Long-Term Sensorimotor Deficits After Ischemic Stroke Likely Through Nrf2.

scientific article published on 23 March 2018

Limb Remote Ischemic Conditioning: Mechanisms, Anesthetics, and the Potential for Expanding Therapeutic Options.

scientific article published on 6 February 2018

Local Delivery Is Critical for Monocyte Chemotactic Protein-1 Mediated Site-Specific Murine Aneurysm Healing.

scientific article published on 19 March 2018

Myelin‐associated glycoprotein protects neurons from excitotoxicity ⬇️

scientific article published on January 7, 2011

Neuronal overexpression of cyclooxygenase-2 increases cerebral infarction.

scientific article published in August 2003

Neuroprotection and enhancement of spatial memory by herbal mixture HT008-1 in rat global brain ischemia model.

scientific article published in January 2008

Neuroprotective action of bilirubin against oxidative stress in primary hippocampal cultures

scientific article published on 01 January 1999

Neuroprotective effect of HT008-1, a prescription of traditional Korean medicine, on transient focal cerebral ischemia model in rats.

scientific article published in August 2010

Neuroprotective effert of carbon monoxide and Nrf2 in cerebral ischemia.

scientific article published on 12 June 2015

Neuroprotective properties of prostaglandin I2 IP receptor in focal cerebral ischemia.

scientific article published on 14 July 2010

Neuroprotective role of prostaglandin PGE2 EP2 receptor in hemin-mediated toxicity

scientific article

Neurovascular protection by post-ischemic intravenous injections of the lipoxin A4 receptor agonist, BML-111, in a rat model of ischemic stroke

scientific article published on December 2013

Nrf2 Plays an Essential Role in Long-Term Brain Damage and Neuroprotection of Korean Red Ginseng in a Permanent Cerebral Ischemia Model

scientific article published on 03 August 2019

Optimized protocol to reduce variable outcomes for the bilateral common carotid artery occlusion model in mice.

scientific article

Oral administration of the flavanol (-)-epicatechin bolsters endogenous protection against focal ischemia through the Nrf2 cytoprotective pathway.

scientific article published on 23 September 2013

PGD(2) DP1 receptor protects brain from ischemia-reperfusion injury.

scientific article published on 16 June 2007

PGE2 EP1 receptor deletion attenuates 6-OHDA-induced Parkinsonism in mice: old switch, new target.

scientific article

PGE2 EP1 receptor exacerbated neurotoxicity in a mouse model of cerebral ischemia and Alzheimer's disease.

scientific article published on 19 October 2011

PGE2-EP3 signaling exacerbates intracerebral hemorrhage outcomes in 24-mo-old mice

scientific article published on 15 April 2016

Presence and differential internalization of two distinct insulin-like growth factor receptors in rat hippocampal neurons.

scientific article published on May 1997

Pretreatment with Korean red ginseng or dimethyl fumarate attenuates reactive gliosis and confers sustained neuroprotection against cerebral hypoxic-ischemic damage by an Nrf2-dependent mechanism

scientific article published on 17 November 2018

Prostacyclin receptor deletion aggravates hippocampal neuronal loss after bilateral common carotid artery occlusion in mouse.

scientific article

Prostaglandin E2 EP2 receptor deletion attenuates intracerebral hemorrhage-induced brain injury and improves functional recovery

scientific article

Prostaglandin E2 stimulates incorporation of proline into collagenase digestible proteins in human articular chondrocytes: identification of an effector autocrine loop involving insulin-like growth factor I

scientific article published on 01 October 1996

Prostaglandin EP4 receptor agonist protects against acute neurotoxicity

scientific article published on 01 December 2005

Prostaglandin F2α FP receptor antagonist improves outcomes after experimental traumatic brain injury

scientific article

Prostaglandin FP receptor inhibitor reduces ischemic brain damage and neurotoxicity ⬇️

scientific article published on June 16, 2012

Protective and rescuing abilities of IGF-I and some putative free radical scavengers against beta-amyloid-inducing toxicity in neurons.

scientific article published in January 1999

Putative role of prostaglandin receptor in intracerebral hemorrhage.

scientific article

Reactive Gliosis Contributes to Nrf2-Dependent Neuroprotection by Pretreatment with Dimethyl Fumarate or Korean Red Ginseng Against Hypoxic-Ischemia: Focus on Hippocampal Injury

scientific article published on 07 September 2019

Rediscovering good old friend IGF-I in the new millenium: possible usefulness in Alzheimer's disease and stroke.

scientific article

Reduced acute brain injury in PGE2 EP3 receptor-deficient mice after cerebral ischemia.

scientific article published on 08 February 2009

Regulation of heme oxygenase expression by cyclopentenone prostaglandins.

scientific article published in May 2003

Resveratrol protects against experimental stroke: putative neuroprotective role of heme oxygenase 1.

scientific article

Role of Interleukin-10 in Acute Brain Injuries.

scientific article

Role of PGE₂ EP1 receptor in intracerebral hemorrhage-induced brain injury

scientific article published on 04 July 2013

Role of heme oxygenase-2 in pial arteriolar response to acetylcholine in mice with and without transfusion of cell-free hemoglobin polymers.

scientific article published on 21 May 2008

Role of reactive oxygen species in modulation of Nrf2 following ischemic reperfusion injury

scientific article

Role of the PGE2 receptor subtypes EP1, EP2, and EP3 in repetitive traumatic brain injury

scientific article published on 16 October 2019

Role of the prostaglandin E2 EP1 receptor in traumatic brain injury

scientific article

Selective blockade of PGE2 EP1 receptor protects brain against experimental ischemia and excitotoxicity, and hippocampal slice cultures against oxygen-glucose deprivation.

scientific article

Serine racemase deletion protects against cerebral ischemia and excitotoxicity

scientific article

Stimulation of prostaglandin E2-EP3 receptors exacerbates stroke and excitotoxic injury.

scientific article published on 2 February 2007

Stroke outcomes in mice lacking the genes for neuronal heme oxygenase-2 and nitric oxide synthase

scientific article published on 01 January 2005

Systemic administration of kainic acid induces selective time dependent decrease in [125I]insulin-like growth factor I, [125I]insulin-like growth factor II and [125I]insulin receptor binding sites in adult rat hippocampal formation.

scientific article published in October 1997

The Ginkgo biloba extract (EGb 761) protects hippocampal neurons against cell death induced by beta-amyloid.

scientific article published in June 2000

The PGE2 EP2 receptor and its selective activation are beneficial against ischemic stroke.

scientific article

The absence of the CD163 receptor has distinct temporal influences on intracerebral hemorrhage outcomes

scientific article published in January 2017

The development of an improved preclinical mouse model of intracerebral hemorrhage using double infusion of autologous whole blood

scientific article

The flavanol (−)-epicatechin prevents stroke damage through the Nrf2/HO1 pathway.

scientific article published on 2 April 2014

Translating basic science research to clinical application: models and strategies for intracerebral hemorrhage.

scientific article

Unique Properties Associated with the Brain Penetrant Iron Chelator HBED Reveal Remarkable Beneficial Effects after Brain Trauma

scientific article published on 25 July 2018

Use of an optimized transient occlusion of the middle cerebral artery protocol for the mouse stroke model.

scientific article published in July 2006

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