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List of works by Guy Berchem

A high rate of telomeric sister chromatid exchange occurs in chronic lymphocytic leukaemia B-cells.

scientific article published on 11 March 2016

A secreted FGF-binding protein can serve as the angiogenic switch in human cancer.

scientific article

Actin Cytoskeleton Remodeling Drives Breast Cancer Cell Escape from Natural Killer-Mediated Cytotoxicity

scientific article published on 13 August 2018

Activation of NK cells and disruption of PD-L1/PD-1 axis: two different ways for lenalidomide to block myeloma progression

scientific article published on 9 February 2017

Assessing cellular and circulating miRNA recovery: the impact of the RNA isolation method and the quantity of input material

scientific article

Autophagic degradation of GZMB/granzyme B: a new mechanism of hypoxic tumor cell escape from natural killer cell-mediated lysis

scientific article

Autophagy: an adaptive metabolic response to stress shaping the antitumor immunity

scientific article

BAG6/BAT3 modulates autophagy by affecting EP300/p300 intracellular localization

scientific journal article

Blocking hypoxia-induced autophagy in tumors restores cytotoxic T-cell activity and promotes regression.

scientific article

Bronchial airway gene expression in smokers with lung or head and neck cancer

scientific article published on 04 February 2014

CD47 is a direct target of SNAI1 and ZEB1 and its blockade activates the phagocytosis of breast cancer cells undergoing EMT.

scientific article published on 15 February 2018

CRP2, a new invadopodia actin bundling factor critically promotes breast cancer cell invasion and metastasis

scientific article published on 11 February 2016

Case Report: Primary Spinal Lymphoma

scientific article published in January 2016

Cathepsin-D affects multiple tumor progression steps in vivo: proliferation, angiogenesis and apoptosis

scientific article published on 01 August 2002

Cell-free DNA and next-generation sequencing in the service of personalized medicine for lung cancer.

scientific article published on 30 August 2016

Clinical benefit from erythropoietin.

scientific article published in July 2000

Cooperative effects of Janus and Aurora kinase inhibition by CEP701 in cells expressing Jak2V617F.

scientific article published on 10 January 2013

Determination of genes and microRNAs involved in the resistance to fludarabine in vivo in chronic lymphocytic leukemia

scientific article

Disruption of autophagy by the histone deacetylase inhibitor MGCD0103 and its therapeutic implication in B-cell chronic lymphocytic leukemia.

scientific article

Driving Cytotoxic Natural Killer Cells into Melanoma: If CCL5 Plays the Music, Autophagy Calls the Shots

scientific article published on 01 January 2018

Driving Natural Killer cells toward the melanoma tumor battlefield: Autophagy as a valuable therapeutic target

scientific article published on 25 April 2018

Dual PD1/LAG3 immune checkpoint blockade limits tumor development in a murine model of chronic lymphocytic leukemia

scientific article published on 13 February 2018

Epigenetic Activity of Peroxisome Proliferator-Activated Receptor Gamma Agonists Increases the Anticancer Effect of Histone Deacetylase Inhibitors on Multiple Myeloma Cells

scientific article published on 19 June 2015

Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts

scientific article

Extended Magnetic Reconnection across the Dayside Magnetopause

scientific article published in Physical Review Letters

Firing up the cold tumors by targeting Vps34

scientific article published on 31 August 2020

Granzyme B degradation by autophagy decreases tumor cell susceptibility to natural killer-mediated lysis under hypoxia

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

High-dimensional mass cytometry analysis revealed microenvironment complexity in chronic lymphocytic leukemia.

scientific article published on 24 May 2018

Hijacker of the Antitumor Immune Response: Autophagy Is Showing Its Worst Facet

scientific article

Hypoxia promotes breast cancer cell invasion through HIF-1α-mediated up-regulation of the invadopodial actin bundling protein CSRP2.

scientific article published on 5 July 2018

Hypoxia-induced autophagy: a new player in cancer immunotherapy?

scientific article published in April 2012

Hypoxic tumor-derived microvesicles negatively regulate NK cell function by a mechanism involving TGF-β and miR23a transfer

scientific article

Identification of a Blood-Based Protein Biomarker Panel for Lung Cancer Detection

scientific article published on 19 June 2020

Identification of beta-arrestin-1 as a diagnostic biomarker in lung cancer

scientific article published on 06 August 2018

Immune surveillance of human cancer: if the cytotoxic T-lymphocytes play the music, does the tumoral system call the tune?

scientific article

Improvement of exercise-induced cardiac deformation after cell therapy for severe chronic ischemic heart failure

scientific article published on 01 March 2006

Improving Cancer Immunotherapy by Targeting the Hypoxic Tumor Microenvironment: New Opportunities and Challenges

scientific article published on 14 September 2019

Inhibition of HIF1α-Dependent Upregulation of Phospho-l-Plastin Resensitizes Multiple Myeloma Cells to Frontline Therapy.

scientific article published on 23 May 2018

Inhibition of Vps34 reprograms cold into hot inflamed tumors and improves anti-PD-1/PD-L1 immunotherapy

scientific article published on 29 April 2020

Intrinsic Resistance of Chronic Lymphocytic Leukemia Cells to NK Cell-Mediated Lysis Can Be Overcome <i>In Vitro</i> by Pharmacological Inhibition of Cdc42-Induced Actin Cytoskeleton Remodeling

scientific article published on 24 May 2021

Lighting up the fire in cold tumors to improve cancer immunotherapy by blocking the activity of the autophagy-related protein PIK3C3/VPS34

scientific article published on 05 September 2020

MicroRNA as biomarkers and regulators in B-cell chronic lymphocytic leukemia.

scientific article

Overexpression of both catalytically active and -inactive cathepsin D by cancer cells enhances apoptosis-dependent chemo-sensitivity

scientific article

Prospective Evaluation of First-Line Erlotinib in Advanced Non-Small Cell Lung Cancer (NSCLC) Carrying an Activating EGFR Mutation: A Multicenter Academic Phase II Study in Caucasian Patients (FIELT).

scientific article

Quantification of SAA1 and SAA2 in lung cancer plasma using the isotype-specific PRM assays.

scientific article

Randomized Phase II Study of Cabazitaxel Versus Methotrexate in Patients With Recurrent and/or Metastatic Squamous Cell Carcinoma of the Head and Neck Previously Treated With Platinum-Based Therapy.

scientific article

Resistance to apoptosis and up regulation of Bcl-2 in benign prostatic hyperplasia after androgen deprivation

scientific article published on 01 July 1997

Screening protein isoforms predictive for cancer using immunoaffinity capture and fast LC-MS in PRM mode.

scientific article

Stromal cell-induced miRNA alteration in chronic lymphocytic leukemia: how a minute and unavoidable cell contamination impairs miRNA profiling.

scientific article

Targeting Autophagy in the Tumor Microenvironment: New Challenges and Opportunities for Regulating Tumor Immunity.

scientific article published on 25 April 2018

Targeting autophagy blocks melanoma growth by bringing natural killer cells to the tumor battlefield.

scientific article published on 25 January 2018

Targeting autophagy inhibits melanoma growth by enhancing NK cells infiltration in a CCL5-dependent manner

scientific article published on 16 October 2017

The acquisition of resistance to TNFα in breast cancer cells is associated with constitutive activation of autophagy as revealed by a transcriptome analysis using a custom microarray.

scientific article published on July 2011

The actin filament cross-linker L-plastin confers resistance to TNF-alpha in MCF-7 breast cancer cells in a phosphorylation-dependent manner

scientific article published on 03 October 2009

The clinical impact of using complex molecular profiling strategies in routine oncology practice. ⬇️

scientific article

The critical role of the tumor microenvironment in shaping natural killer cell-mediated anti-tumor immunity.

scientific article published on 25 December 2013

The histone deacetylase inhibitor MGCD0103 induces apoptosis in B-cell chronic lymphocytic leukemia cells through a mitochondria-mediated caspase activation cascade.

scientific article published on 20 April 2010

The human epidermal growth factor receptor (EGFR) gene in European patients with advanced colorectal cancer harbors infrequent mutations in its tyrosine kinase domain ⬇️

scientific article published on October 25, 2011

The multifaceted role of autophagy in tumor evasion from immune surveillance

scientific article published on 20 February 2016

The prohibitin-binding compound fluorizoline induces apoptosis in chronic lymphocytic leukemia cells ex vivo but fails to prevent leukemia development in a murine model

scientific article published on 5 January 2018

Valproate synergizes with purine nucleoside analogues to induce apoptosis of B-chronic lymphocytic leukaemia cells

scientific article

Verification of the biomarker candidates for non-small-cell lung cancer using a targeted proteomics approach

scientific article published on 09 February 2015

miR-210 and hypoxic microvesicles: Two critical components of hypoxia involved in the regulation of killer cells function.

scientific article

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