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List of works by Carlos Henrique Serezani

5-Lipoxygenase deficiency impairs innate and adaptive immune responses during fungal infection.

scientific article published on 20 March 2012

Cutting edge: macrophage inhibition by cyclic AMP (cAMP): differential roles of protein kinase A and exchange protein directly activated by cAMP-1.

scientific article

Cyclic AMP: master regulator of innate immune cell function.

scientific article published on 06 March 2008

Differential stem- and progenitor-cell trafficking by prostaglandin E2.

scientific article published on 13 March 2013

Distinct protein kinase A anchoring proteins direct prostaglandin E2 modulation of Toll-like receptor signaling in alveolar macrophages.

scientific article

E-prostanoid 3 receptor deletion improves pulmonary host defense and protects mice from death in severe Streptococcus pneumoniae infection

scientific article

EP4 and EP2 receptor activation of protein kinase A by prostaglandin E2 impairs macrophage phagocytosis of Clostridium sordellii.

scientific article published on August 2013

Essential role of leukotriene B4 on Leishmania (Viannia) braziliensis killing by human macrophages

scientific article published on 6 September 2014

Evaluation of the murine immune response to Leishmania meta 1 antigen delivered as recombinant protein or DNA vaccine.

scientific article published on November 2002

FcgammaRI ligation leads to a complex with BLT1 in lipid rafts that enhances rat lung macrophage antimicrobial functions

scientific journal article

Imbalance between HDAC and HAT activities drives aberrant STAT1/MyD88 expression in macrophages from type 1 diabetic mice.

scientific article published on 7 August 2016

Inhibitors of the 5-lipoxygenase arachidonic acid pathway induce ATP release and ATP-dependent organic cation transport in macrophages

scientific article published on 15 April 2014

Innate Immunity to : Evolving Paradigms in Soft Tissue and Invasive Infections

scientific article published on 01 June 2018

Intestinal host defense outcome is dictated by PGE2 production during efferocytosis of infected cells

scientific article published on 20 August 2018

Leukotriene B4 amplifies NF-κB activation in mouse macrophages by reducing SOCS1 inhibition of MyD88 expression

scientific article

Leukotriene B4 as a Potential Therapeutic Target for the Treatment of Metabolic Disorders

scientific article

Leukotriene B4 enhances innate immune defense against the puerperal sepsis agent Streptococcus pyogenes.

scientific article published on 16 January 2013

Leukotriene B4 licenses inflammasome activation to enhance skin host defense

scientific article published on 12 November 2020

Leukotriene B4 mediates p47phox phosphorylation and membrane translocation in polyunsaturated fatty acid-stimulated neutrophils.

scientific article published on 8 July 2005

Leukotrienes Are Essential for the Control of Leishmania amazonensis Infection and Contribute to Strain Variation in Susceptibility

scientific article published on 01 September 2006

Leukotrienes are potent adjuvant during fungal infection: effects on memory T cells.

scientific article published in December 2008

Leukotrienes enhance the bactericidal activity of alveolar macrophages against Klebsiella pneumoniae through the activation of NADPH oxidase

scientific journal article

Leukotrienes target F-actin/cofilin-1 to enhance alveolar macrophage anti-fungal activity.

scientific article

Lipoxin Inhibits Fungal Uptake by Macrophages and Reduces the Severity of Acute Pulmonary Infection Caused by Paracoccidioides brasiliensis

scientific article

Macrophage Dectin-1 Expression Is Controlled by Leukotriene B4 via a GM-CSF/PU.1 Axis ⬇️

scientific article published on June 13, 2012

Macrophage-derived LTB4 promotes abscess formation and clearance of Staphylococcus aureus skin infection in mice

scientific article published on 13 August 2018

MicroRNA 21 is a homeostatic regulator of macrophage polarization and prevents prostaglandin E2-mediated M2 generation

scientific article

Murine Colitis is Mediated by Vimentin ⬇️

scientific article published on January 9, 2013

NADPH oxidase deficiency results in reduced alveolar macrophage 5-lipoxygenase expression and decreased leukotriene synthesis.

scientific article published on 30 August 2007

Nuclear PTEN enhances the maturation of a microRNA regulon to limit MyD88-dependent susceptibility to sepsis.

scientific article

Opposing roles of LTB4 and PGE2 in regulating the inflammasome-dependent scorpion venom-induced mortality.

scientific article published on 23 February 2016

Outer surface protein OspC is an antiphagocytic factor that protects Borrelia burgdorferi from phagocytosis by macrophages.

scientific article

PAFR activation of NF-κB p65 or p105 precursor dictates pro- and anti-inflammatory responses during TLR activation in murine macrophages

scientific article published on 24 August 2016

PPAR-γ/IL-10 axis inhibits MyD88 expression and ameliorates murine polymicrobial sepsis

scientific article published on 31 January 2014

PTEN directly activates the actin depolymerization factor cofilin-1 during PGE2-mediated inhibition of phagocytosis of fungi

scientific article

Proinflammatory responses of heme in alveolar macrophages: repercussion in lung hemorrhagic episodes.

scientific article published on 17 April 2013

Prostaglandin E2 restrains macrophage maturation via E prostanoid receptor 2/protein kinase A signaling.

scientific article published on 10 January 2012

Prostaglandin E2 suppresses bacterial killing in alveolar macrophages by inhibiting NADPH oxidase

scientific article

Prostaglandin E2–Induced Changes in Alveolar Macrophage Scavenger Receptor Profiles Differentially Alter Phagocytosis of Pseudomonas aeruginosa and Staphylococcus aureus Post–Bone Marrow Transplant ⬇️

scientific article published on April 29, 2013

Prostaglandin and the Suppression of Phagocyte Innate Immune Responses in Different Organs ⬇️

scientific article published on September 13, 2012

Regulation of alveolar macrophage p40phox: hierarchy of activating kinases and their inhibition by PGE2

scientific article

Role of granulocyte macrophage colony-stimulating factor during gram-negative lung infection with Pseudomonas aeruginosa.

scientific article published on 10 February 2006

Role of p85α in neutrophil extra- and intracellular reactive oxygen species generation

scientific article published on 30 March 2016

Sepsis Induces Hematopoietic Stem Cell Exhaustion and Myelosuppression through Distinct Contributions of TRIF and MYD88.

scientific article published on 02 June 2016

Specific leukotriene receptors couple to distinct G proteins to effect stimulation of alveolar macrophage host defense functions.

scientific article published in October 2007

Synthetic Prostacyclin Analogs Differentially Regulate Macrophage Function via Distinct Analog-Receptor Binding Specificities

scientific article published on 01 February 2007

TLR4/MYD88-dependent, LPS-induced synthesis of PGE2 by macrophages or dendritic cells prevents anti-CD3-mediated CD95L upregulation in T cells.

scientific article published on 26 September 2008

The class A scavenger receptor, macrophage receptor with collagenous structure, is the major phagocytic receptor for Clostridium sordellii expressed by human decidual macrophages.

scientific article published in September 2010

The leukotriene B₄/BLT₁ axis is a key determinant in susceptibility and resistance to histoplasmosis

scientific article published on 21 January 2014

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