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List of works by Leilei Chen

A disrupted RNA editing balance mediated by ADARs (Adenosine DeAminases that act on RNA) in human hepatocellular carcinoma

scientific article

ADAR-Mediated RNA Editing Predicts Progression and Prognosis of Gastric Cancer.

scientific article published on 30 June 2016

ADAR1: a promising new biomarker for esophageal squamous cell carcinoma?

scientific article published on 13 June 2014

AKR7A3 suppresses tumorigenicity and chemoresistance in hepatocellular carcinoma through attenuation of ERK, c-Jun and NF-κB signaling pathways.

scientific article published on 18 October 2016

AZIN1 RNA editing confers cancer stemness and enhances oncogenic potential in colorectal cancer

scientific article published on 21 June 2018

Aberrant hyperediting of the myeloma transcriptome by ADAR1 confers oncogenicity and is a marker of poor prognosis

scientific article published on 30 July 2018

Adenosine-to-inosine RNA editing mediated by ADARs in esophageal squamous cell carcinoma

scientific article published on 3 December 2013

An RNA editing/dsRNA binding-independent gene regulatory mechanism of ADARs and its clinical implication in cancer

scientific article published on 29 July 2017

ApoA-1 accelerates regeneration of small-for-size fatty liver graft after transplantation

scientific article published on 26 October 2018

Author Correction: Systematic evaluation and optimization of the experimental steps in RNA G-quadruplex structure sequencing

scientific article published on 26 February 2020

Bidirectional regulation of adenosine-to-inosine (A-to-I) RNA editing by DEAH box helicase 9 (DHX9) in cancer

scientific article published on 01 September 2018

CAV1 - GLUT3 signaling is important for cellular energy and can be targeted by Atorvastatin in Non-Small Cell Lung Cancer

scientific article published on 14 August 2019

CHD1L promotes hepatocellular carcinoma progression and metastasis in mice and is associated with these processes in human patients.

scientific article

CHD1L promotes lineage reversion of hepatocellular carcinoma through opening chromatin for key developmental transcription factors.

scientific article published on 4 March 2016

Characterization of CACNA2D3 as a putative tumor suppressor gene in the development and progression of nasopharyngeal carcinoma.

scientific article published on 13 July 2013

Characterization of the oncogenic function of centromere protein F in hepatocellular carcinoma.

scientific article published on 17 June 2013

Characterization of tumor-suppressive function of SOX6 in human esophageal squamous cell carcinoma.

scientific article published on 17 November 2010

Chemically-Induced Cancers Do Not Originate from Bone Marrow-Derived Cells

scientific article published on January 24, 2012

Chromodomain helicase/adenosine triphosphatase DNA binding protein 1-like (CHD1l) gene suppresses the nucleus-to-mitochondria translocation of nur77 to sustain hepatocellular carcinoma cell survival.

scientific article

Chromosome 1q21 amplification and oncogenes in hepatocellular carcinoma.

scientific article published on 02 August 2010

Cis- and trans-regulations of pre-mRNA splicing by RNA editing enzymes influence cancer development

scientific article published on 07 February 2020

Clinical significance of CHD1L in hepatocellular carcinoma and therapeutic potentials of virus-mediated CHD1L depletion.

scientific article published on 10 November 2010

Down-regulation of tyrosine aminotransferase at a frequently deleted region 16q22 contributes to the pathogenesis of hepatocellular carcinoma.

scientific article published in May 2010

Downregulation of the novel tumor suppressor DIRAS1 predicts poor prognosis in esophageal squamous cell carcinoma.

scientific article published on 22 February 2013

Establishment and characterization of human non-small cell lung cancer cell lines

scientific article published on 3 October 2011

Fatty acid synthase mediates EGFR palmitoylation in EGFR mutated non-small cell lung cancer

scientific article published on 15 February 2018

Interleukin 17A promotes hepatocellular carcinoma metastasis via NF-kB induced matrix metalloproteinases 2 and 9 expression.

scientific article

Interleukin 23 promotes hepatocellular carcinoma metastasis via NF-kappa B induced matrix metalloproteinase 9 expression

scientific article

Loss of ATOH8 Increases Stem Cell Features of Hepatocellular Carcinoma Cells

scientific article

MicroRNA-375 inhibits tumour growth and metastasis in oesophageal squamous cell carcinoma through repressing insulin-like growth factor 1 receptor

scientific article published on August 3, 2011

Multilayered control of splicing regulatory networks by DAP3 leads to widespread alternative splicing changes in cancer

scientific article published on 04 April 2022

Overexpression of GPR39 contributes to malignant development of human esophageal squamous cell carcinoma.

scientific article

Overexpression of N-terminal kinase like gene promotes tumorigenicity of hepatocellular carcinoma by regulating cell cycle progression and cell motility.

scientific article

Overexpression of cathepsin Z contributes to tumor metastasis by inducing epithelial-mesenchymal transition in hepatocellular carcinoma

scientific article

Overexpression of eukaryotic initiation factor 5A2 enhances cell motility and promotes tumor metastasis in hepatocellular carcinoma.

scientific article

RNA editome imbalance in hepatocellular carcinoma.

scientific article published on 20 February 2014

Recoding RNA editing of AZIN1 predisposes to hepatocellular carcinoma

scientific article published on 06 January 2013

Regulatory factors governing adenosine-to-inosine (A-to-I) RNA editing

scientific article

Role of translationally controlled tumor protein in cancer progression.

scientific article published on 17 April 2012

SCYL1 binding protein 1 promotes the ubiquitin-dependent degradation of Pirh2 and has tumor-suppressive function in the development of hepatocellular carcinoma.

scientific article published on 7 May 2012

SPOCK1 is regulated by CHD1L and blocks apoptosis and promotes HCC cell invasiveness and metastasis in mice.

scientific article published on 25 September 2012

Serum and glucocorticoid kinase 3 at 8q13.1 promotes cell proliferation and survival in hepatocellular carcinoma.

scientific article published on 23 April 2012

Suppression of adenosine-to-inosine (A-to-I) RNA editome by death associated protein 3 (DAP3) promotes cancer progression

scientific article published on 17 June 2020

Systematic evaluation and optimization of the experimental steps in RNA G-quadruplex structure sequencing

scientific article published on 30 May 2019

Transgenic CHD1L expression in mouse induces spontaneous tumors

scientific article