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List of works by Zoe Johnson

An engineered monomer of CCL2 has anti-inflammatory properties emphasizing the importance of oligomerization for chemokine activity in vivo.

scientific article published on 28 July 2008

Antibody Neutralization of CXCL10 in Vivo Is Dependent on Binding to Free and Not Endothelial-bound Chemokine: IMPLICATIONS FOR THE DESIGN OF A NEW GENERATION OF ANTI-CHEMOKINE THERAPEUTIC ANTIBODIES.

scientific article published on 30 January 2017

Characterization of the chemokine CXCL11-heparin interaction suggests two different affinities for glycosaminoglycans.

scientific article

Chemokine Receptor Antagonist Development ⬇️

scientific article published on January 1, 2013

Discovery of a Novel Series of CRTH2 (DP2) Receptor Antagonists Devoid of Carboxylic Acids.

scientific article published on 10 October 2011

Discovery of potent, selective, and orally bioavailable alkynylphenoxyacetic acid CRTH2 (DP2) receptor antagonists for the treatment of allergic inflammatory diseases

scientific article published on 3 October 2011

Evasin-4, a tick-derived chemokine-binding protein with broad selectivity can be modified for use in preclinical disease models

scientific article

Exploiting light chains for the scalable generation and platform purification of native human bispecific IgG.

scientific article

Expression and agonist responsiveness of CXCR3 variants in human T lymphocytes.

scientific article

Glycosaminoglycan Interactions with Chemokines Add Complexity to a Complex System

scientific article published on 9 August 2017

Glycosaminoglycan binding and oligomerization are essential for the in vivo activity of certain chemokines

scholarly article

Identification of the glycosaminoglycan binding site of the CC chemokine, MCP-1: implications for structure and function in vivo.

scientific article published on 18 March 2004

Interference with heparin binding and oligomerization creates a novel anti-inflammatory strategy targeting the chemokine system

scientific article published on 01 November 2004

Novel Insights into Interleukin 6 (IL-6) Cis- and Trans-signaling Pathways by Differentially Manipulating the Assembly of the IL-6 Signaling Complex

scientific article

Oligomerization of RANTES is required for CCR1-mediated arrest but not CCR5-mediated transmigration of leukocytes on inflamed endothelium

scientific article published on 22 May 2003

Optimization of the Central Core of Indolinone-Acetic Acid-Based CRTH2 (DP2) Receptor Antagonists.

scientific article published on 9 June 2011

Preclinical development of a bispecific antibody that safely and effectively targets CD19 and CD47 for the treatment of B cell lymphoma and leukemia.

scientific article

Quantitative detection of therapeutic proteins and their metabolites in serum using antibody-coupled ProteinChip Arrays and SELDI-TOF-MS.

scientific article published on 2 November 2006

Selective Blockade of the Ubiquitous Checkpoint Receptor CD47 Is Enabled by Dual-Targeting Bispecific Antibodies.

scientific article published on February 2017

The X-ray structure of RANTES: heparin-derived disaccharides allows the rational design of chemokine inhibitors.

scientific article

The antiviral restriction factor IFN-induced transmembrane protein 3 prevents cytokine-driven CMV pathogenesis

scientific article

The basic residue cluster (55)KKWVR(59) in CCL5 is required for in vivo biologic function.

scientific article

Use of a mouse model to identify a blood biomarker for IFNγ activity in pediatric secondary hemophagocytic lymphohistiocytosis.

scientific article

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