List of works - Sara Iachettini

A basal level of DNA damage and telomere deprotection increases the sensitivity of cancer cells to G-quadruplex interactive compounds

scientific article

Aromatic core extension in the series of N-cyclic bay-substituted perylene G-quadruplex ligands: increased telomere damage, antitumor activity, and strong selectivity for neoplastic over healthy cells

scientific article

Erratum: identification of novel RHPS4-derivative ligands with improved toxicological profiles and telomere-targeting activities

scientific article published on 5 February 2015

Evidence for G-quadruplex in the promoter of vegfr-2 and its targeting to inhibit tumor angiogenesis

scientific article published on 11 December 2013

Evidence for G-quadruplex in the promoter of VEGFR-2 and its targeting to inhibit tumor angiogenesis.

scientific article

High-sensitive cardiac troponin T (hs-cTnT) assay as serum biomarker to predict cardiac risk in myotonic dystrophy: A case-control study.

scientific article

Identification of novel RHPS4-derivative ligands with improved toxicological profiles and telomere-targeting activities

scientific article

Insights into telomeric G-quadruplex DNA recognition by HMGB1 protein

scientific article published on 01 October 2019

N-cyclic bay-substituted perylene G-quadruplex ligands have selective antiproliferative effects on cancer cells and induce telomere damage

scientific article

On and off-target effects of telomere uncapping G-quadruplex selective ligands based on pentacyclic acridinium salts

scientific article published on 19 September 2013

Perylene and coronene derivatives binding to G-rich promoter oncogene sequences efficiently reduce their expression in cancer cells

scientific article published on 13 April 2016

Pharmacological activation of SIRT6 triggers lethal autophagy in human cancer cells

scientific article published on 24 September 2018

Receptor and post-receptor abnormalities contribute to insulin resistance in myotonic dystrophy type 1 and type 2 skeletal muscle.

scientific article published on 15 September 2017

SIRT6 interacts with TRF2 and promotes its degradation in response to DNA damage.

scientific article

Shooting for Selective Druglike G-Quadruplex Binders: Evidence for Telomeric DNA Damage and Tumor Cell Death

article

Tailoring a lead-like compound targeting multiple G-quadruplex structures

scientific article published on 27 November 2018

Tibialis anterior muscle needle biopsy and sensitive biomolecular methods: a useful tool in myotonic dystrophy type 1

scientific article

List of works by Sara Iachettini

A basal level of DNA damage and telomere deprotection increases the sensitivity of cancer cells to G-quadruplex interactive compounds

Aromatic core extension in the series of N-cyclic bay-substituted perylene G-quadruplex ligands: increased telomere damage, antitumor activity, and strong selectivity for neoplastic over healthy cells

Erratum: identification of novel RHPS4-derivative ligands with improved toxicological profiles and telomere-targeting activities

Evidence for G-quadruplex in the promoter of vegfr-2 and its targeting to inhibit tumor angiogenesis

Evidence for G-quadruplex in the promoter of VEGFR-2 and its targeting to inhibit tumor angiogenesis.

High-sensitive cardiac troponin T (hs-cTnT) assay as serum biomarker to predict cardiac risk in myotonic dystrophy: A case-control study.

Identification of novel RHPS4-derivative ligands with improved toxicological profiles and telomere-targeting activities

Insights into telomeric G-quadruplex DNA recognition by HMGB1 protein

N-cyclic bay-substituted perylene G-quadruplex ligands have selective antiproliferative effects on cancer cells and induce telomere damage

On and off-target effects of telomere uncapping G-quadruplex selective ligands based on pentacyclic acridinium salts

Perylene and coronene derivatives binding to G-rich promoter oncogene sequences efficiently reduce their expression in cancer cells

Pharmacological activation of SIRT6 triggers lethal autophagy in human cancer cells

Receptor and post-receptor abnormalities contribute to insulin resistance in myotonic dystrophy type 1 and type 2 skeletal muscle.

SIRT6 interacts with TRF2 and promotes its degradation in response to DNA damage.

Shooting for Selective Druglike G-Quadruplex Binders: Evidence for Telomeric DNA Damage and Tumor Cell Death

Tailoring a lead-like compound targeting multiple G-quadruplex structures

Tibialis anterior muscle needle biopsy and sensitive biomolecular methods: a useful tool in myotonic dystrophy type 1