List of works - Martin Holzenberger

A French academic network for sharing transgenic materials and knowledge

scientific article published on 01 December 2005

A Targeted Partial Invalidation of the Insulin-Like Growth Factor I Receptor Gene in Mice Causes a Postnatal Growth Deficit

article

Beneficial role of regulatory T cells in a mouse model of Alzheimer's disease

scholarly article by Cira Dansokho et al published October 2014 in Journal of Neuroimmunology

Biology of insulin-like growth factors in development.

scientific article published on November 2003

Blocking IGF Signaling in Adult Neurons Alleviates Alzheimer's Disease Pathology through Amyloid-β Clearance.

scientific article published on August 2015

Body surface area as a parameter of age decline.

scientific article published in September 1991

Brain IGF-1 receptors control mammalian growth and lifespan through a neuroendocrine mechanism

scientific article

CaMKIIα Expression Defines Two Functionally Distinct Populations of Granule Cells Involved in Different Types of Odor Behavior.

scientific article

Components of the hematopoietic compartments in tumor stroma and tumor-bearing mice

scientific article

Cre-mediated germline mosaicism: a method allowing rapid generation of several alleles of a target gene.

scientific article

Cre-mediated recombination in the skin melanocyte lineage.

scientific article published in June 2003

Decelerated growth and longevity in men.

scientific article

Deleting IGF-1 receptor from forebrain neurons confers neuroprotection during stroke and upregulates endocrine somatotropin.

scientific article published on 13 January 2016

Disrupting IGF Signaling in Adult Mice Conditions Leanness, Resilient Energy Metabolism, and High Growth Hormone Pulses.

scientific article

Experimental IGF-I Receptor Deficiency Generates a Sexually Dimorphic Pattern of Organ-Specific Growth Deficits in Mice, Affecting Fat Tissue in Particular

scientific article published in October 2001

Exploring endocrine GH pattern in mice using rank plot analysis and random blood samples.

scientific article

Expression of dominant-negative thyroid hormone receptor alpha1 in Leydig and Sertoli cells demonstrates no additional defect compared with expression in Sertoli cells only

scientific article

Genotyping of Cre-lox mice and detection of tissue-specific recombination by multiplex PCR

scientific article published on 01 November 2001

Hepatocyte proliferation during liver regeneration is impaired in mice with liver-specific IGF-1R knockout

scientific article published on 16 February 2006

High-level IGF1R expression is required for leukemia-initiating cell activity in T-ALL and is supported by Notch signaling

scientific article

Hypothalamic neurogenesis persists in the aging brain and is controlled by energy-sensing IGF-I pathway

scientific article

IGF and insulin signaling pathways in longevity

scientific article published on 13 October 2010

IGF binding protein 2 supports the survival and cycling of hematopoietic stem cells ⬇️

scientific article published on August 5, 2011

IGF signaling contributes to malignant transformation of hematopoietic progenitors by the MLL-AF9 oncoprotein.

scientific article published on 18 May 2012

IGF type 1 receptor ligand binding characteristics are altered in a subgroup of children with intrauterine growth retardation

scientific article published on 01 November 2001

IGF type 1 receptor: a cell cycle progression factor that regulates aging.

scientific article

IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice

scientific article (publication date: 9 January 2003)

IGF-1 signaling and aging.

scientific article

IGF-1R Reduction Triggers Neuroprotective Signaling Pathways in Spinal Muscular Atrophy Mice.

scientific article published on August 2015

IGF-IR determines the fates of BCR/ABL leukemia

scientific article

Igf-I signaling and effects on longevity

scientific article published on 03 October 2011

Igf1r signalling acts on the anagen-to-catagen transition in the hair cycle

scientific article published on 17 January 2017

Inactivation of the IGF-I receptor gene in primary Sertoli cells highlights the autocrine effects of IGF-I.

scientific article published in September 2007

Insulin receptors in beta-cells are critical for islet compensatory growth response to insulin resistance

scholarly article

Insulin-like growth factor 1 receptor regulates hypothermia during calorie restriction

scientific article

Knockout of insulin-like growth factor-1 receptor impairs distal lung morphogenesis

scientific article

Loss of glucagon-like peptide-2-induced proliferation following intestinal epithelial insulin-like growth factor-1-receptor deletion.

scientific article published on 16 September 2011

Major components of the insulin-like growth factor axis are expressed early in chicken embryogenesis, with IGF binding protein ( IGFBP) -5 expression subject to regulation by Sonic Hedgehog.

scientific article published on 13 May 2003

Proinflammatory actions of visfatin/nicotinamide phosphoribosyltransferase (Nampt) involve regulation of insulin signaling pathway and Nampt enzymatic activity.

scientific article published on 7 March 2012

Quantitation of tropoelastin mRNA and assessment of alternative splicing in human skin fibroblasts by reverse transcriptase-polymerase chain reaction

scientific article published on 01 October 1993

Reduced IGF-1 signaling delays age-associated proteotoxicity in mice

scientific article

Regulatory T cells delay disease progression in Alzheimer-like pathology.

scientific article

Selective expression of insulin-like growth factor II in the songbird brain.

scientific article published in September 1997

Suppression of IGF-I signals in neural stem cells enhances neurogenesis and olfactory function during aging.

scientific article

The Alzheimer's disease transcriptome mimics the neuroprotective signature of IGF-1 receptor-deficient neurons.

scientific article

The GH/IGF-I axis and longevity.

scientific article published in August 2004

The intestinal epithelial insulin-like growth factor-1 receptor links glucagon-like peptide-2 action to gut barrier function.

scientific article

The role of insulin-like signalling in the regulation of ageing.

scientific article

Thyrocyte-specific deletion of insulin and IGF-1 receptors induces papillary thyroid carcinoma-like lesions through EGFR pathway activation

scientific article published on 22 September 2018

Total insulin and IGF-I resistance in pancreatic beta cells causes overt diabetes

scientific article published on 23 April 2006

Tropoelastin gene expression in the developing vascular system of the chicken: an in situ hybridization study

scientific article published on 01 November 1993

[Ageing, genetics and the somatotropic axis]

scientific article published on 01 March 2006

[IGF-1 receptors in the brain control longevity in mice]

scientific article published on 01 April 2009

[Objective assessment of biological aging in the human: results]

scientific article published on 01 March 1989

[Two strains of genetically hypertensive rats, LH and SRH, have distinct profiles of postnatal expression of tropoelastin and type III collagen in the aortic wall]

scientific article published on 01 August 1996

List of works by Martin Holzenberger

A French academic network for sharing transgenic materials and knowledge

A Targeted Partial Invalidation of the Insulin-Like Growth Factor I Receptor Gene in Mice Causes a Postnatal Growth Deficit

Beneficial role of regulatory T cells in a mouse model of Alzheimer's disease

Biology of insulin-like growth factors in development.

Blocking IGF Signaling in Adult Neurons Alleviates Alzheimer's Disease Pathology through Amyloid-β Clearance.

Body surface area as a parameter of age decline.

Brain IGF-1 receptors control mammalian growth and lifespan through a neuroendocrine mechanism

CaMKIIα Expression Defines Two Functionally Distinct Populations of Granule Cells Involved in Different Types of Odor Behavior.

Components of the hematopoietic compartments in tumor stroma and tumor-bearing mice

Cre-mediated germline mosaicism: a method allowing rapid generation of several alleles of a target gene.

Cre-mediated recombination in the skin melanocyte lineage.

Decelerated growth and longevity in men.

Deleting IGF-1 receptor from forebrain neurons confers neuroprotection during stroke and upregulates endocrine somatotropin.

Disrupting IGF Signaling in Adult Mice Conditions Leanness, Resilient Energy Metabolism, and High Growth Hormone Pulses.

Experimental IGF-I Receptor Deficiency Generates a Sexually Dimorphic Pattern of Organ-Specific Growth Deficits in Mice, Affecting Fat Tissue in Particular

Exploring endocrine GH pattern in mice using rank plot analysis and random blood samples.

Expression of dominant-negative thyroid hormone receptor alpha1 in Leydig and Sertoli cells demonstrates no additional defect compared with expression in Sertoli cells only

Genotyping of Cre-lox mice and detection of tissue-specific recombination by multiplex PCR

Hepatocyte proliferation during liver regeneration is impaired in mice with liver-specific IGF-1R knockout

High-level IGF1R expression is required for leukemia-initiating cell activity in T-ALL and is supported by Notch signaling

Hypothalamic neurogenesis persists in the aging brain and is controlled by energy-sensing IGF-I pathway

IGF and insulin signaling pathways in longevity

IGF binding protein 2 supports the survival and cycling of hematopoietic stem cells ⬇️

IGF signaling contributes to malignant transformation of hematopoietic progenitors by the MLL-AF9 oncoprotein.

IGF type 1 receptor ligand binding characteristics are altered in a subgroup of children with intrauterine growth retardation

IGF type 1 receptor: a cell cycle progression factor that regulates aging.

IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice

IGF-1 signaling and aging.

IGF-1R Reduction Triggers Neuroprotective Signaling Pathways in Spinal Muscular Atrophy Mice.

IGF-IR determines the fates of BCR/ABL leukemia

Igf-I signaling and effects on longevity

Igf1r signalling acts on the anagen-to-catagen transition in the hair cycle

Inactivation of the IGF-I receptor gene in primary Sertoli cells highlights the autocrine effects of IGF-I.

Insulin receptors in beta-cells are critical for islet compensatory growth response to insulin resistance

Insulin-like growth factor 1 receptor regulates hypothermia during calorie restriction

Knockout of insulin-like growth factor-1 receptor impairs distal lung morphogenesis

Loss of glucagon-like peptide-2-induced proliferation following intestinal epithelial insulin-like growth factor-1-receptor deletion.

Major components of the insulin-like growth factor axis are expressed early in chicken embryogenesis, with IGF binding protein ( IGFBP) -5 expression subject to regulation by Sonic Hedgehog.

Proinflammatory actions of visfatin/nicotinamide phosphoribosyltransferase (Nampt) involve regulation of insulin signaling pathway and Nampt enzymatic activity.

Quantitation of tropoelastin mRNA and assessment of alternative splicing in human skin fibroblasts by reverse transcriptase-polymerase chain reaction

Reduced IGF-1 signaling delays age-associated proteotoxicity in mice

Regulatory T cells delay disease progression in Alzheimer-like pathology.

Selective expression of insulin-like growth factor II in the songbird brain.

Suppression of IGF-I signals in neural stem cells enhances neurogenesis and olfactory function during aging.

The Alzheimer's disease transcriptome mimics the neuroprotective signature of IGF-1 receptor-deficient neurons.

The GH/IGF-I axis and longevity.

The intestinal epithelial insulin-like growth factor-1 receptor links glucagon-like peptide-2 action to gut barrier function.

The role of insulin-like signalling in the regulation of ageing.

Thyrocyte-specific deletion of insulin and IGF-1 receptors induces papillary thyroid carcinoma-like lesions through EGFR pathway activation

Total insulin and IGF-I resistance in pancreatic beta cells causes overt diabetes

Tropoelastin gene expression in the developing vascular system of the chicken: an in situ hybridization study

[Ageing, genetics and the somatotropic axis]

[IGF-1 receptors in the brain control longevity in mice]

[Objective assessment of biological aging in the human: results]

[Two strains of genetically hypertensive rats, LH and SRH, have distinct profiles of postnatal expression of tropoelastin and type III collagen in the aortic wall]