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List of works by Steffan D Bos

A gain of function mutation in TNFRSF11B encoding osteoprotegerin causes osteoarthritis with chondrocalcinosis

scientific article

A genome-wide linkage scan reveals CD53 as an important regulator of innate TNF-alpha levels

scientific article

A meta-analysis of genome-wide association studies identifies novel variants associated with osteoarthritis of the hip

scientific article

A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function

scientific article

Allelic variation at the C-reactive protein gene associates to both hand osteoarthritis severity and serum high sensitive C-reactive protein levels in the GARP study

scientific article published on 29 November 2007

CD8<sup>+</sup> T cell gene expression analysis identifies differentially expressed genes between multiple sclerosis patients and healthy controls

scientific article published on 01 October 2020

Fourteen sequence variants that associate with multiple sclerosis discovered by meta-analysis informed by genetic correlations

scientific article published on 8 August 2017

From genetic associations to functional studies in multiple sclerosis.

scientific article published on 7 March 2016

GREM1, FRZB and DKK1 mRNA levels correlate with osteoarthritis and are regulated by osteoarthritis-associated factors.

scientific article published on 19 September 2013

Genes expressed in blood link osteoarthritis with apoptotic pathways.

scientific article published on 17 July 2013

Genes involved in the osteoarthritis process identified through genome wide expression analysis in articular cartilage; the RAAK study.

scientific article

Genetic overlap between multiple sclerosis and several cardiovascular disease risk factors

scientific article

Genetic variants are major determinants of CSF antibody levels in multiple sclerosis

scientific article published on 22 January 2015

Genome-wide DNA methylation profiles indicate CD8+ T cell hypermethylation in multiple sclerosis

scientific article

Identification and systematic annotation of tissue-specific differentially methylated regions using the Illumina 450k array

scientific article published on 06 August 2013

Identification of DIO2 as a new susceptibility locus for symptomatic osteoarthritis

scientific article published on 11 March 2008

Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study ⬇️

scientific article published on July 3, 2012

Incidence of gastrointestinal stromal tumours is underestimated: results of a nation-wide study

scientific article published on 15 November 2005

Increased DNA methylation of SLFN12 in CD4+ and CD8+ T cells from multiple sclerosis patients

scientific article published in PLoS ONE

Increased type II deiodinase protein in OA-affected cartilage and allelic imbalance of OA risk polymorphism rs225014 at DIO2 in human OA joint tissues

scientific article published on 04 April 2012

Interleukin-1 gene cluster variants with innate cytokine production profiles and osteoarthritis in subjects from the Genetics, Osteoarthritis and Progression Study

scientific article

Knee and hip articular cartilage have distinct epigenomic landscapes: implications for future cartilage regeneration approaches.

scientific article published on 26 September 2014

Low frequency and rare coding variation contributes to multiple sclerosis risk

Meta-analyses of genes modulating intracellular T3 bio-availability reveal a possible role for the DIO3 gene in osteoarthritis susceptibility

scientific article published on 19 August 2010

Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22

scientific article

Metabolic health in families enriched for longevity is associated with low prevalence of hand osteoarthritis and influences OA biomarker profiles

scientific article published on 27 October 2012

Multiple Sclerosis Risk Allele in CLEC16A Acts as an Expression Quantitative Trait Locus for CLEC16A and SOCS1 in CD4+ T Cells

scientific article published on 23 July 2015

Multiple sclerosis risk loci and disease severity in 7,125 individuals from 10 studies

scientific article published on 04 August 2016

New insights into osteoarthritis: early developmental features of an ageing-related disease.

scientific article published on September 2008

No differential gene expression for CD4+ T cells of MS patients and healthy controls

scientific article published on 01 April 2019

Oligoclonal bands and age at onset correlate with genetic risk score in multiple sclerosis

scientific article

Pregnancy does not modify the risk of MS in genetically susceptible women

scientific article published on 09 October 2020

Retinoic acid enhances the levels of IL-10 in TLR-stimulated B cells from patients with relapsing-remitting multiple sclerosis

scientific article published on 24 November 2014

The Multiple Sclerosis Genomic Map: Role of peripheral immune cells and resident microglia in susceptibility

scholarly article published 13 July 2017

The multiple sclerosis susceptibility genes TAGAP and IL2RA are regulated by vitamin D in CD4+ T cells.

scientific article

The role of plasma cytokine levels, CRP and Selenoprotein S gene variation in OA

scientific article published on 25 October 2008

Transcriptional associations of osteoarthritis-mediated loss of epigenetic control in articular cartilage

scientific article published on May 2015

Underlying molecular mechanisms of DIO2 susceptibility in symptomatic osteoarthritis

scientific article published on 2 April 2014

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