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List of works by Helen B Pearson

A Chemical Screening Approach to Identify Novel Key Mediators of Erythroid Enucleation

scientific article

Copper as a target for prostate cancer therapeutics: copper-ionophore pharmacology and altering systemic copper distribution.

scientific article published on 09 May 2016

Dissecting the role of polarity regulators in cancer through the use of mouse models.

scientific article published on 30 August 2014

Endogenous c-Myc is essential for p53-induced apoptosis in response to DNA damage in vivo

scientific article published on 28 February 2014

Estrogen receptor alpha drives proliferation in PTEN-deficient prostate carcinoma by stimulating survival signaling, MYC expression and altering glucose sensitivity

scientific article

Frizzled-7 Is Required for Wnt Signaling in Gastric Tumors with and Without Apc Mutations

scientific article published on 08 January 2019

Functional and molecular characterisation of EO771.LMB tumours, a new C57BL/6-mouse-derived model of spontaneously metastatic mammary cancer

scientific article

Identification of Pik3ca Mutation as a Genetic Driver of Prostate Cancer That Cooperates with Pten Loss to Accelerate Progression and Castration-Resistant Growth

scientific article published on 26 March 2018

Increasing intracellular bioavailable copper selectively targets prostate cancer cells

scientific article published on 24 May 2013

Keratin 76 is required for tight junction function and maintenance of the skin barrier.

scientific article

Lkb1 deficiency alters goblet and paneth cell differentiation in the small intestine

scientific article

Myb via TGFβ is required for collagen type 1 production and skin integrity.

scientific article

Partial inhibition of gp130-Jak-Stat3 signaling prevents Wnt-β-catenin-mediated intestinal tumor growth and regeneration.

scientific article published on 30 September 2014

SCRIB expression is deregulated in human prostate cancer, and its deficiency in mice promotes prostate neoplasia

scientific article published on 3 October 2011

Scrib heterozygosity predisposes to lung cancer and cooperates with KRas hyperactivation to accelerate lung cancer progression in vivo.

scientific article published on 25 November 2013

Scribble modulates the MAPK/Fra1 pathway to disrupt luminal and ductal integrity and suppress tumour formation in the mammary gland

scientific article

The PTEN Conundrum: How to Target PTEN-Deficient Prostate Cancer

scientific article published on 22 October 2020

The polarity protein Scrib mediates epidermal development and exerts a tumor suppressive function during skin carcinogenesis

scientific article

[10]-gingerol induces apoptosis and inhibits metastatic dissemination of triple negative breast cancer in vivo

scientific article published on 10 August 2017

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