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List of works by Bhopal C Mohapatra

A kinase inhibitor screen reveals protein kinase C-dependent endocytic recycling of ErbB2 in breast cancer cells.

scientific article

A novel CBL-Bflox/flox mouse model allows tissue-selective fully conditional CBL/CBL-B double-knockout: CD4-Cre mediated CBL/CBL-B deletion occurs in both T-cells and hematopoietic stem cells.

scientific article published on 03 June 2016

An essential role of CBL and CBL-B ubiquitin ligases in mammary stem cell maintenance

scientific article published on 18 January 2017

CBL family E3 ubiquitin ligases control JAK2 ubiquitination and stability in hematopoietic stem cells and myeloid malignancies.

scientific article published on 13 June 2017

Cbl-family ubiquitin ligases and their recruitment of CIN85 are largely dispensable for epidermal growth factor receptor endocytosis.

scientific article

Continuous requirement of ErbB2 kinase activity for loss of cell polarity and lumen formation in a novel ErbB2/Neu-driven murine cell line model of metastatic breast cancer.

scientific article published on 30 November 2011

ESCRT proteins: Double-edged regulators of cellular signaling ⬇️

scientific article published on January 1, 2011

Fasudil, a clinically safe ROCK inhibitor, decreases disease burden in a Cbl/Cbl-b deficiency-driven murine model of myeloproliferative disorders

scientific article published on 15 July 2015

Loss of Cbl and Cbl-b ubiquitin ligases abrogates hematopoietic stem cell quiescence and sensitizes leukemic disease to chemotherapy.

scientific article

Loss of the nuclear pool of ubiquitin ligase CHIP/STUB1 in breast cancer unleashes the MZF1-cathepsin pro-oncogenic program.

scientific article published on 6 March 2018

Marked enhancement of lysosomal targeting and efficacy of ErbB2-targeted drug delivery by HSP90 inhibition

scientific article

Mutant Cbl proteins as oncogenic drivers in myeloproliferative disorders

scientific article

Polypeptide-based nanogels co-encapsulating a synergistic combination of doxorubicin with 17-AAG show potent anti-tumor activity in ErbB2-driven breast cancer models.

scientific article published on 3 February 2015

Protein tyrosine kinase regulation by ubiquitination: critical roles of Cbl-family ubiquitin ligases

scientific article

Structural Determinants of the Gain-of-Function Phenotype of Human Leukemia-associated Mutant CBL Oncogene.

scientific article published on 12 January 2017

The endocytic recycling regulatory protein EHD1 Is required for ocular lens development

scientific article

VAV1-Cre mediated hematopoietic deletion of CBL and CBL-B leads to JMML-like aggressive early-neonatal myeloproliferative disease

scientific article published on 16 July 2016

c-Cbl inhibition improves cardiac function and survival in response to myocardial ischemia

scientific article

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