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List of works by Benjamin G Barwick

14-3-3ζ binds the proteasome, limits proteolytic function and enhances sensitivity to proteasome inhibitors.

scientific article published on 19 September 2017

A heterozygous IDH1R132H/WT mutation induces genome-wide alterations in DNA methylation.

scientific article

ATAC-seq on biobanked specimens defines a unique chromatin accessibility structure in naïve SLE B cells

scientific article published on June 2016

Aberrant Extrafollicular B Cells, Immune Dysfunction, Myeloid Inflammation, and MyD88-Mutant Progenitors Precede Waldenstrom Macroglobulinemia

scientific article published on 01 September 2021

Acetylation of KLF5 maintains EMT and tumorigenicity to cause chemoresistant bone metastasis in prostate cancer

scientific article published on 17 March 2021

Age-associated DNA methylation in pediatric populations

scientific article

B cell activation and plasma cell differentiation are inhibited by de novo DNA methylation.

scientific article

CD86 regulates myeloma cell survival

scientific article published on 16 November 2017

Cell of Origin and Genetic Alterations in the Pathogenesis of Multiple Myeloma.

scientific article published on 21 May 2019

Chromatin Accessibility Identifies Regulatory Elements Predictive of Gene Expression and Disease Outcome in Multiple Myeloma

scientific article published on 17 March 2021

Common distal elements orchestrate CIITA isoform-specific expression in multiple cell types

scientific article

Conserved Region C Functions To Regulate PD-1 Expression and Subsequent CD8 T Cell Memory.

scientific article published on 28 November 2016

DNA extraction from formalin-fixed, paraffin-embedded tissue

scientific article published on 01 February 2009

Differential activation of Wnt-β-catenin pathway in triple negative breast cancer increases MMP7 in a PTEN dependent manner

scientific article

EZH2 Represses the B Cell Transcriptional Program and Regulates Antibody-Secreting Cell Metabolism and Antibody Production

scientific article published on 29 December 2017

Electron transport chain activity is a predictor and target for venetoclax sensitivity in multiple myeloma

scientific article published on 06 March 2020

Epigenetic programming underpins B cell dysfunction in human SLE

scientific article published on 01 July 2019

Epigenetically heterogeneous tumor cells direct collective invasion through filopodia-driven fibronectin micropatterning

scientific article published on 24 July 2020

Factors affecting the persistence of drug-induced reprogramming of the cancer methylome

scientific article published on 15 April 2016

Gain of Chromosome 1q is associated with early progression in multiple myeloma patients treated with lenalidomide, bortezomib, and dexamethasone

scientific article published on 25 November 2019

Galactic Cosmic Radiation Induces Persistent Epigenome Alterations Relevant to Human Lung Cancer.

scientific article

Genetic heterogeneity within collective invasion packs drives leader and follower cell phenotypes

scientific article published on 09 October 2019

Global DNA methylation remodeling accompanies CD8 T cell effector function.

scientific article published on 16 August 2013

Heterozygosity for Pten promotes tumorigenesis in a mouse model of medulloblastoma

scientific article

Integrated phosphoproteomics and transcriptional classifiers reveal hidden RAS signaling dynamics in multiple myeloma

scientific article published on 01 November 2019

LSD1 protects against hippocampal and cortical neurodegeneration

scientific article published on 9 October 2017

MAX is an epigenetic sensor of 5-carboxylcytosine and is altered in multiple myeloma

scientific article

Molecular characterisation of formalin-fixed paraffin-embedded (FFPE) breast tumour specimens using a custom 512-gene breast cancer bead array-based platform.

scientific article published on November 2011

Multiple myeloma immunoglobulin lambda translocations portend poor prognosis

scientific article published on 23 April 2019

Multivariant Transcriptome Analysis Identifies Modules and Hub Genes Associated with Poor Outcomes in Newly Diagnosed Multiple Myeloma Patients

scientific article published on 29 April 2022

PD-1 Expression during Acute Infection Is Repressed through an LSD1-Blimp-1 Axis

scientific article published on 06 December 2019

Plasma cell differentiation is controlled by multiple cell division-coupled epigenetic programs.

scientific article published on 27 April 2018

Plasma cell differentiation is coupled to division-dependent DNA hypomethylation and gene regulation

scientific article published on 08 August 2016

Prostate cancer genes associated with TMPRSS2-ERG gene fusion and prognostic of biochemical recurrence in multiple cohorts.

scientific article published on 12 January 2010

The Histone Demethylase LSD1 Regulates B Cell Proliferation and Plasmablast Differentiation

scientific article published on 19 September 2018

Venetoclax ex vivo functional profiling predicts improved progression-free survival

scientific article published in 2022

Whole-genome analysis of TET dioxygenase function in regulatory T cells

scientific article published on 21 July 2021

Wnt signaling in triple negative breast cancer is associated with metastasis

scientific article

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