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List of works by Josée Golay

A human immunodeficiency virus type 1 pol gene-derived sequence (cPPT/CTS) increases the efficiency of transduction of human nondividing monocytes and T lymphocytes by lentiviral vectors

scientific article published in October 2002

A novel method using blinatumomab for efficient, clinical-grade expansion of polyclonal T cells for adoptive immunotherapy

scientific article published on 29 September 2014

A phase II multiple dose clinical trial of histone deacetylase inhibitor ITF2357 in patients with relapsed or progressive multiple myeloma

scientific article

A simple and rapid method to analyze specific mRNAs from few cells in a semi-quantitative way using the polymerase chain reaction ⬇️

scientific article published on November 1, 1991

A-Myb up-regulates Bcl-2 through a Cdx binding site in t(14;18) lymphoma cells.

scientific article

A-myb rescues murine B-cell lymphomas from IgM-receptor-mediated apoptosis through c-myc transcriptional regulation

scientific article published on 01 August 2000

Acquired immunodeficiency syndrome-associated lymphomas are efficiently lysed through complement-dependent cytotoxicity and antibody-dependent cellular cytotoxicity by rituximab

scientific article published in December 2002

Antitumour effects of single or combined monoclonal antibodies directed against membrane antigens expressed by human B cells leukaemia

scientific article

Autologous mesenchymal stromal cells and kidney transplantation: a pilot study of safety and clinical feasibility.

scientific article

B cells in patients with X-linked and 'common variable' hypogammaglobulinaemia

scientific article published on 01 July 1986

Biologic response of B lymphoma cells to anti-CD20 monoclonal antibody rituximab in vitro: CD55 and CD59 regulate complement-mediated cell lysis.

scientific article

CD20 levels determine the in vitro susceptibility to rituximab and complement of B-cell chronic lymphocytic leukemia: further regulation by CD55 and CD59

scientific article published on 01 December 2001

Characterization of CD20-transduced T lymphocytes as an alternative suicide gene therapy approach for the treatment of graft-versus-host disease.

scientific article published in January 2004

Characterization of the c-Myb-responsive region and regulation of the human type I collagen alpha 2 chain gene by c-Myb.

scientific article

Characterization of the new immunosuppressive drug undecylprodigiosin in human lymphocytes: retinoblastoma protein, cyclin-dependent kinase-2, and cyclin-dependent kinase-4 as molecular targets

scientific article published on 01 April 1997

Chemokines and antagonists in non-Hodgkin's lymphoma

scientific article published on 01 May 2008

Clinical grade expansion of MSCs

scientific article published on 17 June 2015

Combined Anti-Cancer Strategies Based on Anti-Checkpoint Inhibitor Antibodies

scientific article published on 20 May 2020

Comment on "Reduced T-dependent humoral immunity in CD20-deficient mice".

scientific article

Complement activation determines the therapeutic activity of rituximab in vivo.

scientific article

Complement in antibody therapy: friend or foe?

scientific article published on 01 December 2009

Cytokine Induced Killer (CIK) cells for the treatment of haematological neoplasms.

scientific article published on 29 September 2013

Cytokine-induced killer cells are terminally differentiated activated CD8 cytotoxic T-EMRA lymphocytes.

scientific article published in May 2009

Design and Validation of a Novel Generic Platform for the Production of Tetravalent IgG1-like Bispecific Antibodies.

scientific article published on 26 February 2016

Detection of a transcriptional block in the first intron of the human c-myb gene.

scientific article published on January 1992

Differential response of human acute myeloid leukemia cells to gemtuzumab ozogamicin in vitro: role of Chk1 and Chk2 phosphorylation and caspase 3.

scientific article

Direct involvement of CD56 in cytokine-induced killer-mediated lysis of CD56+ hematopoietic target cells.

scientific article published on 6 September 2014

Direct targeting of cancer cells with antibodies: What can we learn from the successes and failure of unconjugated antibodies for lymphoid neoplasias?

scientific article published on 27 June 2017

Dissociation between p93B-myb and p75c-myb expression during the proliferation and differentiation of human myeloid cell lines.

scientific article

Dual-functional capability of CD3+CD56+ CIK cells, a T-cell subset that acquires NK function and retains TCR-mediated specific cytotoxicity.

scientific article

Effect of alemtuzumab on neoplastic B cells.

scientific article

Elongation factor 1 (EF1alpha) promoter in a lentiviral backbone improves expression of the CD20 suicide gene in primary T lymphocytes allowing efficient rituximab-mediated lysis.

scientific article published on January 2004

Enhanced killing of human B-cell lymphoma targets by combined use of cytokine-induced killer cell (CIK) cultures and anti-CD20 antibodies.

scientific article published on 3 November 2010

Expression of A-myb, but not c-myb and B-myb, is restricted to Burkitt's lymphoma, sIg+ B-acute lymphoblastic leukemia, and a subset of chronic lymphocytic leukemias.

scientific article published on March 1996

FcgammaRIIIA and FcgammaRIIA polymorphisms do not predict clinical outcome of follicular non-Hodgkin's lymphoma patients treated with sequential CHOP and rituximab

scientific article published on 01 August 2007

Feasibility and safety of adoptive immunotherapy with CIK cells after cord blood transplantation.

scientific article

Frequent occurrence of non-malignant genetic alterations in clinical grade mesenchymal stromal cells expanded for cell therapy protocols.

scientific article published on 28 March 2014

From the bench to the bedside: ways to improve rituximab efficacy.

scientific article published on 29 June 2004

Gemtuzumab ozogamicin (Mylotarg) has therapeutic activity against CD33 acute lymphoblastic leukaemias in vitro and in vivo.

scientific article published in February 2005

Givinostat and hydroxyurea synergize in vitro to induce apoptosis of cells from JAK2(V617F) myeloproliferative neoplasm patients.

scientific article

Glycoengineered CD20 antibody obinutuzumab activates neutrophils and mediates phagocytosis through CD16B more efficiently than rituximab

scientific article published on 8 October 2013

Human neutrophils express low levels of FcγRIIIA, which plays a role in PMN activation

scientific article published on 17 January 2019

Human neutrophils mediate trogocytosis rather than phagocytosis of CLL B cells opsonized with anti-CD20 antibodies

scientific article

Human platelet lysate allows expansion and clinical grade production of mesenchymal stromal cells from small samples of bone marrow aspirates or marrow filter washouts.

scientific article published on 6 August 2007

Ibrutinib interferes with the cell-mediated anti-tumor activities of therapeutic CD20 antibodies: implications for combination therapy

scientific article

Independent regulation of c-myc, B-myb, and c-myb gene expression by inducers and inhibitors of proliferation in human B lymphocytes ⬇️

scientific article published on July 1, 1992

Inducible expression of PTX3, a new member of the pentraxin family, in human mononuclear phagocytes.

scientific article

Innovative cell-based therapies in onco-hematology: what are the clinical facts ?

scientific article published in October 2004

Isolation and characterization of the human A-myb promoter: regulation by NF-Y and Sp1.

scientific article published on August 2000

Lentiviral vectors show dramatically increased efficiency of transduction of human leukemic cell lines

scientific article published on 01 October 2001

Lepidopteran cells, an alternative for the production of recombinant antibodies?

scientific article

Lessons for the clinic from rituximab pharmacokinetics and pharmacodynamics

scientific article

M2 macrophages phagocytose rituximab-opsonized leukemic targets more efficiently than m1 cells in vitro.

scientific article published on April 2009

Mechanism of action of therapeutic monoclonal antibodies: Promises and pitfalls of in vitro and in vivo assays ⬇️

scientific article published on February 25, 2012

Mechanism of action of type II, glycoengineered, anti-CD20 monoclonal antibody GA101 in B-chronic lymphocytic leukemia whole blood assays in comparison with rituximab and alemtuzumab

scientific article published on 4 February 2011

Mesenchymal stromal cells for the treatment of graft-versus-host disease: understanding the in vivo biological effect through patient immune monitoring

scientific article published on 13 January 2012

Minimally manipulated whole human umbilical cord is a rich source of clinical-grade human mesenchymal stromal cells expanded in human platelet lysate

scientific article published on 18 March 2011

Mutations in v-myb alter the differentiation of myelomonocytic cells transformed by the oncogene.

scientific article published in December 1990

New immunosuppressive drug PNU156804 blocks IL-2-dependent proliferation and NF-kappa B and AP-1 activation.

scientific article

Ofatumumab is more efficient than rituximab in lysing B chronic lymphocytic leukemia cells in whole blood and in combination with chemotherapy

scientific article published on 5 December 2012

Phase II Study of Sequential Infusion of Donor Lymphocyte Infusion and Cytokine-Induced Killer Cells for Patients Relapsed after Allogeneic Hematopoietic Stem Cell Transplantation.

scientific article published on 13 July 2017

Platelet-lysate-Expanded Mesenchymal Stromal Cells as a Salvage Therapy for Severe Resistant Graft-versus-Host Disease in a Pediatric Population

scientific article published on 27 March 2010

Pleiotropic anti-myeloma activity of ITF2357: inhibition of interleukin-6 receptor signaling and repression of miR-19a and miR-19b

scientific article

Possible misinterpretation of the mode of action of therapeutic antibodies in vitro: homotypic adhesion and flow cytometry result in artefactual direct cell death

scientific article published on 01 October 2010

Rapid retroviral infection of human haemopoietic cells of different lineages: efficient transfer in fresh T cells.

scientific article published on November 1998

Redundant functions of B-Myb and c-Myb in differentiating myeloid cells ⬇️

scientific article published on December 1, 1997

Repeated infusions of donor-derived cytokine-induced killer cells in patients relapsing after allogeneic stem cell transplantation: a phase I study

scientific article published in July 2007

Rituximab-mediated antibody-dependent cellular cytotoxicity against neoplastic B cells is stimulated strongly by interleukin-2.

scientific article published on September 2003

Rituximab: a new therapeutic tool for primary immune thrombocytopenic purpura?

scientific article published on 01 May 2003

Small dose of rituximab for graves orbitopathy: new insights into the mechanism of action

scientific article published on 01 January 2012

Synergism between fludarabine and rituximab revealed in a follicular lymphoma cell line resistant to the cytotoxic activity of either drug alone.

scientific article

The A-Myb Transcription Factor in Neoplastic and Normal B Cells ⬇️

scientific article published on July 1, 1997

The A-Myb transcription factor is a marker of centroblasts in vivo.

scientific article published in March 1998

The A-myb gene is preferentially expressed in tonsillar CD38+, CD39-, and sIgM- B lymphocytes and in Burkitt's lymphoma cell lines

scientific article published on 01 July 1994

The CCL3 family of chemokines and innate immunity cooperate in vivo in the eradication of an established lymphoma xenograft by rituximab.

scientific article published on May 2007

The CD20 (Bp35) antigen is involved in activation of B cells from the G0 to the G1 phase of the cell cycle.

scientific article

The DNA Binding Domain of the A-MYB Transcription Factor Is Responsible for Its B Cell-specific Activity and Binds to a B Cell 110-kDa Nuclear Protein ⬇️

scientific article published on October 3, 1997

The HDAC inhibitor Givinostat modulates the hematopoietic transcription factors NFE2 and C-MYB in JAK2(V617F) myeloproliferative neoplasm cells

scientific article published on 8 May 2012

The Polo-Like Kinase 1 (PLK1) inhibitor NMS-P937 is effective in a new model of disseminated primary CD56+ acute monoblastic leukaemia

scientific article

The Role of Complement in the Mechanism of Action of Therapeutic Anti-Cancer mAbs

scientific article published on 28 October 2020

The human A-myb protein is a strong activator of transcription

scientific article

The in vivo mechanism of action of CD20 monoclonal antibodies depends on local tumor burden.

scientific article published on 31 August 2011

The sensitivity of acute lymphoblastic leukemia cells carrying the t(12;21) translocation to campath-1H-mediated cell lysis.

scientific article published on March 2006

The specific Bruton tyrosine kinase inhibitor acalabrutinib (ACP-196) shows favorable in vitro activity against chronic lymphocytic leukemia B cells with CD20 antibodies

scientific article published on 22 June 2017

The toll-like receptor repertoire of human B lymphocytes: inducible and selective expression of TLR9 and TLR10 in normal and transformed cells

scientific article

Therapeutic efficacy of the pan-cdk inhibitor PHA-793887 in vitro and in vivo in engraftment and high-burden leukemia models.

scientific article

Treatment of graft versus host disease with mesenchymal stromal cells: a phase I study on 40 adult and pediatric patients

scientific article published on 7 December 2013

Utility of routine evaluation of sterility of cellular therapy products with or without extensive manipulation: Best practices and clinical significance

scientific article published on 12 December 2017

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