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List of works by David Holcman

A mechanism for the polarity formation of chemoreceptors at the growth cone membrane for gradient amplification during directional sensing

scientific article

Advances Using Single-Particle Trajectories to Reconstruct Chromatin Organization and Dynamics

scientific article published on 29 July 2019

Alpha rhythm collapse predicts iso-electric suppressions during anesthesia

scientific article published on 02 September 2019

Analysis and Interpretation of Superresolution Single-Particle Trajectories

scientific article

Analysis of Single Locus Trajectories for Extracting In Vivo Chromatin Tethering Interactions

scientific article published on 28 August 2015

Astroglial networks scale synaptic activity and plasticity.

scientific article

Astroglial networks: a step further in neuroglial and gliovascular interactions.

scientific article published on February 2010

Barriers to diffusion in dendrites and estimation of calcium spread following synaptic inputs

scientific article (publication date: October 2011)

Brownian needle in dire straits: stochastic motion of a rod in very confined narrow domains.

scientific article published on 5 January 2012

Bursting reverberation as a multiscale neuronal network process driven by synaptic depression-facilitation

scientific article published on 27 May 2015

Calcium dynamics in dendritic spines and spine motility.

scientific article published on July 2004

Calcium dynamics in dendritic spines, modeling and experiments.

scientific article

Computation of the Mean First-Encounter Time Between the Ends of a Polymer Chain ⬇️

scientific article published on September 5, 2012

Computational and mathematical methods for morphogenetic gradient analysis, boundary formation and axonal targeting

scientific article published on 04 September 2014

Computing the length of the shortest telomere in the nucleus.

scientific article published on 27 November 2013

Connexin 30 sets synaptic strength by controlling astroglial synapse invasion

scientific article published on 2 March 2014

Control of flux by narrow passages and hidden targets in cellular biology.

scientific article published on 20 June 2013

Deconvolution of Voltage Sensor Time Series and Electro-diffusion Modeling Reveal the Role of Spine Geometry in Controlling Synaptic Strength

scientific article published on 5 February 2018

Detection of single photons by toad and mouse rods.

scientific article

Diffusing polymers in confined microdomains and estimation of chromosomal territory sizes from chromosome capture data.

scientific article published on 14 June 2013

Diffusion in a dendritic spine: the role of geometry.

scientific article published on 21 August 2007

Diffusion in narrow domains and application to phototransduction

scientific article published on 17 March 2009

Dissection of a Krox20 positive feedback loop driving cell fate choices in hindbrain patterning

scientific article published on January 2013

Do cells sense time by number of divisions?

scientific article published on 09 May 2018

Dwell time of a Brownian molecule in a microdomain with traps and a small hole on the boundary.

scientific article published in June 2007

Dynamic regulation of spine-dendrite coupling in cultured hippocampal neurons.

scientific article published in November 2004

Electrical transient laws in neuronal microdomains based on electro-diffusion

scientific article published on 01 August 2018

Electrostatics of non-neutral biological microdomains.

scientific article published on 12 September 2017

Emergence and fragmentation of the alpha-band driven by neuronal network dynamics

scientific article published on 06 December 2021

Encounter dynamics of a small target by a polymer diffusing in a confined domain.

scientific article published in December 2012

Engrailed homeoprotein recruits the adenosine A1 receptor to potentiate ephrin A5 function in retinal growth cones.

scientific article published in January 2012

Estimating the Synaptic Current in a Multiconductance AMPA Receptor Model ⬇️

scientific article published on August 17, 2011

Estimating the rate constant of cyclic GMP hydrolysis by activated phosphodiesterase in photoreceptors.

scientific article

Extreme escape from a cusp: When does geometry matter for the fastest Brownian particles moving in crowded cellular environments?

scientific article published on 01 April 2020

Fast calcium transients in dendritic spines driven by extreme statistics

scientific article published on 04 June 2019

Fast calcium transients in neuronal spines driven by extreme statistics

Fastest among equals: a novel paradigm in biology: Reply to comments: Redundancy principle and the role of extreme statistics in molecular and cellular biology

scientific article published on 01 March 2019

Gated narrow escape time for molecular signaling.

scientific article published on 30 September 2009

Histone degradation in response to DNA damage enhances chromatin dynamics and recombination rates.

scientific article published on 9 January 2017

How rods respond to single photons: Key adaptations of a G-protein cascade that enable vision at the physical limit of perception

scientific article

Hybrid Markov-mass action law model for cell activation by rare binding events: Application to calcium induced vesicular release at neuronal synapses

scientific article published on 18 October 2016

Kinetics of aggregation with a finite number of particles and application to viral capsid assembly.

scientific article published on 8 August 2014

Longitudinal diffusion in retinal rod and cone outer segment cytoplasm: the consequence of cell structure.

scientific article

Mixed analytical-stochastic simulation method for the recovery of a Brownian gradient source from probability fluxes to small windows

scientific article

Modeling the spontaneous activity of the auditory cortex.

scientific article published in December 2005

Modeling the step of endosomal escape during cell infection by a nonenveloped virus

scientific article published on 6 March 2012

Modeling the voltage distribution in a non-locally but globally electroneutral confined electrolyte medium: applications for nanophysiology

scientific article published in 2021

Monitoring and predicting SARS-CoV-2 epidemic in France after deconfinement using a multiscale age-stratified rate model

scientific article published on 20 May 2020

Narrow escape for a stochastically gated Brownian ligand ⬇️

scientific article published on January 22, 2010

Narrow escape through a funnel and effective diffusion on a crowded membrane.

scientific article published on 5 August 2011

Narrow escape time to a structured target located on the boundary of a microdomain

scientific article published on 01 March 2009

Oscillatory decay of the survival probability of activated diffusion across a limit cycle.

scientific article published on 7 March 2014

Physical principles and models describing intracellular virus particle dynamics.

scientific article published on 14 July 2009

Polymer model with long-range interactions: analysis and applications to the chromatin structure.

scientific article published on 27 November 2013

Post-transcriptional regulation in the nucleus and cytoplasm: study of mean time to threshold (MTT) and narrow escape problem.

scientific article published on 8 April 2014

Quantifying intermittent transport in cell cytoplasm.

scientific article published on 24 March 2008

Quantifying neurite growth mediated by interactions among secretory vesicles, microtubules, and actin networks.

scientific article published on February 2009

Quantitative analysis of virus and plasmid trafficking in cells.

scientific article published on 28 January 2009

Reconstructing the gradient source position from steady-state fluxes to small receptors.

scientific article published on 17 January 2018

Recovering a stochastic process from super-resolution noisy ensembles of single-particle trajectories ⬇️

scientific article published on 9 November 2015

Redundancy principle and the role of extreme statistics in molecular and cellular biology

scientific article published on 11 January 2019

Reply to 'Only negligible deviations from electroneutrality are expected in dendritic spines'

scientific article published on 07 November 2019

Residence times of receptors in dendritic spines analyzed by stochastic simulations in empirical domains. ⬇️

scientific article

Robust network oscillations during mammalian respiratory rhythm generation driven by synaptic dynamics

scientific article

Search for a small egg by spermatozoa in restricted geometries

scientific article published on 26 December 2015

Single particle trajectories reveal active endoplasmic reticulum luminal flow

scientific article published on 17 September 2018

Spatial telomere organization and clustering in yeast Saccharomyces cerevisiae nucleus is generated by a random dynamics of aggregation-dissociation

scientific article published on 10 April 2013

Statistics of chromatin organization during cell differentiation revealed by heterogeneous cross-linked polymers

scientific article published on 14 June 2019

Statistics of randomly cross-linked polymer models to interpret chromatin conformation capture data

scientific article published on 27 July 2017

Steady-state voltage distribution in three-dimensional cusp-shaped funnels modeled by PNP

scientific article published on 09 April 2019

Stochastic chemical reactions in microdomains.

scientific article published in March 2005

Stochastic modeling of gene activation and applications to cell regulation.

scientific article published in December 2010

Structural Fluctuations of the Chromatin Fiber within Topologically Associating Domains

scientific article published on March 2016

Synapse geometry and receptor dynamics modulate synaptic strength

scientific article

Synaptic dynamics and neuronal network connectivity are reflected in the distribution of times in Up states

scientific article

Synaptic transmission in neurological disorders dissected by a quantitative approach ⬇️

scientific article published on September 1, 2012

Syntaxin1A Lateral Diffusion Reveals Transient and Local SNARE Interactions

scientific article published on 01 November 2011

The Length of the Shortest Telomere as the Major Determinant of the Onset of Replicative Senescence ⬇️

scientific article published on 03 June 2013

The WQN algorithm to adaptively correct artifacts in the EEG signal

scientific article published in 2022

The dynamics of phosphodiesterase activation in rods and cones

scientific article published on 7 December 2007

The emergence of Up and Down states in cortical networks

scientific article

The narrow escape problem for diffusion in cellular microdomains

scholarly article

The neuroglial potassium cycle during neurotransmission: role of Kir4.1 channels

scientific article published on 31 March 2015

The new nanophysiology: regulation of ionic flow in neuronal subcompartments.

scientific article published on 14 October 2015

Threshold activation for stochastic chemical reactions in microdomains.

scientific article published on 12 April 2010

Transcription factor search for a DNA promoter in a three-state model ⬇️

scientific article published on August 8, 2011

Transient chromatin properties revealed by polymer models and stochastic simulations constructed from Chromosomal Capture data

scientific article

Two loci single particle trajectories analysis: constructing a first passage time statistics of local chromatin exploration.

scientific article published on 4 September 2017

Unraveling novel features hidden in superresolution microscopy data ⬇️

scientific article published on May 1, 2013

Using default constraints of the spindle assembly checkpoint to estimate the associated chemical rates ⬇️

scientific article published on January 19, 2012

Visualization of Chromatin Decompaction and Break Site Extrusion as Predicted by Statistical Polymer Modeling of Single-Locus Trajectories.

scientific article published in January 2017

Why so many sperm cells?

scientific article

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