List of works - Christoph W Müller

A bromodomain-DNA interaction facilitates acetylation-dependent bivalent nucleosome recognition by the BET protein BRDT.

scientific article

A firm hand on NFkappaB: structures of the IkappaBalpha-NFkappaB complex.

scientific article

A synthetic biology approach to probing nucleosome symmetry.

scientific article published on 12 September 2017

A systematic screen for protein-lipid interactions in Saccharomyces cerevisiae

scientific article

An integrated approach for genome annotation of the eukaryotic thermophile Chaetomium thermophilum

scientific article published on 14 November 2014

Analyzing RNA polymerase III by electron cryomicroscopy.

scientific article published on September 2011

Architecture of CRM1/Exportin1 suggests how cooperativity is achieved during formation of a nuclear export complex

scientific article

Architecture of TFIIIC and its role in RNA polymerase III pre-initiation complex assembly.

scientific article published on 10 June 2015

Architecture of the yeast Elongator complex

scientific article (publication date: February 2017)

Automated structure modeling of large protein assemblies using crosslinks as distance restraints

scientific article

Bacterial expression, purification, and crystallization of tyrosine phosphorylated STAT proteins

scientific article

Chromatin-modifying Complex Component Nurf55/p55 Associates with Histones H3 and H4 and Polycomb Repressive Complex 2 Subunit Su(z)12 through Partially Overlapping Binding Sites

scientific article

Comparison of two different DMA-binding modes of the NF-κB p50 homodimer

scientific article published on 01 March 1996

Complex Interdependence Regulates Heterotypic Transcription Factor Distribution and Coordinates Cardiogenesis

scientific article

Conformational flexibility of RNA polymerase III during transcriptional elongation.

scientific article

Cooperative binding of two acetylation marks on a histone tail by a single bromodomain

scientific article

Cryo-EM structures of human RNA polymerase I

scientific article published on 09 December 2021

Crystal structure and functional analysis of a nucleosome recognition module of the remodeling factor ISWI

scientific article

Crystal structure of the 14-subunit RNA polymerase I

scientific article

Crystal structure of the M1 protein-binding domain of the influenza A virus nuclear export protein (NEP/NS2)

scientific article published in September 2003

Crystal structure of the ankyrin repeat domain of Bcl-3: a unique member of the IkappaB protein family.

scientific article

Crystallographic structure of the T domain-DNA complex of the Brachyury transcription factor

scientific article

Delineation of two functional regions of transcription factor TFIIB.

scientific article

Different TBX5 interactions in heart and limb defined by Holt-Oram syndrome mutations

scientific article

Du nouveau dans la compréhension de la reprogrammation postméiotique du génome mâle

scientific article published on 01 February 2010

Editorial overview: Protein-nucleic acid interactions: An expanding universe

scientific article published in December 2017

Elongator: transcriptional or translational regulator?

scientific article published on 14 August 2012

Engineering of diffraction-quality crystals of the NF-κB P52 homodimer:DNA complex

scientific article published on 01 April 1997

Expression, proteolytic analysis, reconstitution, and crystallization of the τ60/τ91 subcomplex of yeast TFIIIC

scientific article published on 26 July 2005

Expression, purification, crystallization and preliminary X-ray analysis of a C-terminal fragment of the Epstein-Barr virus ZEBRA protein

scientific article published on 10 February 2006

Full repression of RNA polymerase III transcription requires interaction between two domains of its negative regulator Maf1

scientific article

HDAC6-p97/VCP controlled polyubiquitin chain turnover

scientific journal article

Histone H2A monoubiquitination promotes histone H3 methylation in Polycomb repression

scientific article published on 18 May 2014

Human importin alpha and RNA do not compete for binding to influenza A virus nucleoprotein.

scientific article published on 25 October 2010

In-cell architecture of the nuclear pore and snapshots of its turnover

scientific article published on 02 September 2020

Induced-fit movements in adenylate kinases

scientific article published on 01 June 1990

Insights into the Function of the CRM1 Cofactor RanBP3 from the Structure of Its Ran-Binding Domain

scientific article

Insights into transcription initiation and termination from the electron microscopy structure of yeast RNA polymerase III.

scientific article published on March 2007

Interaction of influenza virus proteins with nucleosomes.

scientific article

Karyopherin flexibility in nucleocytoplasmic transport

scientific article

Mass spectrometry reveals stable modules in holo and apo RNA polymerases I and III.

scientific article published in January 2011

Molecular Structures of Transcribing RNA Polymerase I.

scientific article published on 16 November 2016

Molecular architecture of polycomb repressive complexes

scientific article

Molecular basis of tRNA recognition by the Elongator complex

scientific article published on 10 July 2019

Molecular insight into RNA polymerase I promoter recognition and promoter melting

scientific article published on 05 December 2019

Molecular mechanism of promoter opening by RNA polymerase III.

scientific article published in January 2018

Molecular recognition of histone lysine methylation by the Polycomb group repressor dSfmbt

scientific article

Molecular structures of unbound and transcribing RNA polymerase III.

scientific article published on 25 November 2015

Nuclear import factors importin α and importin β undergo mutually induced conformational changes upon association

article

Pervasive Protein Thermal Stability Variation during the Cell Cycle.

scientific article published on 21 April 2018

Preparation and Properties of Oligodeoxynucleotides Containing 5-Iodouracil and 5-Bromo- and 5-Iodocytosine

scientific article published on 01 September 1997

Protein–nucleic acid interactions: some assembly required

article published in 2007

RNA polymerase I and III: similar yet unique

scientific article published on 22 July 2017

RNA polymerase III initiation on coligo DNA templates containing loops of variable sequence, size and nucleotide chemistry

scientific article published in September 2016

RNA polymerase III-specific general transcription factor IIIC contains a heterodimer resembling TFIIF Rap30/Rap74

scientific article

Recognizing and remodeling the nucleosome

scientific article published on 04 March 2011

Solution study of the NF-kappaB p50-DNA complex by UV laser protein-DNA cross-linking

scientific article published in June 2003

Solving the NES problem ⬇️

scientific article published on November 1, 2010

Solving the RNA polymerase I structural puzzle

scientific article

Specialization versus conservation: How Pol I and Pol III use the conserved architecture of the pre-initiation complex for specialized transcription

scientific article published on 21 June 2016

Structural Basis for the Activation of the Deubiquitinase Calypso by the Polycomb Protein ASX

scientific article published on 10 January 2019

Structural and Functional Characterization of a Phosphatase Domain within Yeast General Transcription Factor IIIC

scientific article

Structural and functional analyses of methyl-lysine binding by the malignant brain tumour repeat protein Sex comb on midleg

scientific article

Structural asymmetry in the eukaryotic Elongator complex

scientific article published on 28 September 2017

Structural basis for LEAFY floral switch function and similarity with helix-turn-helix proteins

scientific article

Structural basis for RNA polymerase III transcription repression by Maf1

scientific article published on 17 February 2020

Structural basis for tRNA modification by Elp3 from Dehalococcoides mccartyi

scientific article

Structural basis for targeting the chromatin repressor Sfmbt to Polycomb response elements

scientific article

Structural basis of TBX5-DNA recognition: the T-box domain in its DNA-bound and -unbound form

scientific article

Structural basis of lytic cycle activation by the Epstein-Barr virus ZEBRA protein

scientific article

Structural insights into Elongator function ⬇️

scientific article published on March 16, 2013

Structural insights into transcription initiation by yeast RNA polymerase I.

scientific article published on 24 July 2017

Structure of a truncation mutant of the nuclear export factor CRM1 provides insights into the auto-inhibitory role of its C-terminal helix

scientific article

Structure of an activated Dictyostelium STAT in its DNA-unbound form

scientific article published in March 2004

Structure of importin-beta bound to the IBB domain of importin-alpha

scientific article

Structure of the DNA-bound T-box domain of human TBX3, a transcription factor responsible for ulnar-mammary syndrome

scientific article

Structure of the Drosophila nucleosome core particle highlights evolutionary constraints on the H2A-H2B histone dimer

scientific article

Structure of the GCM domain-DNA complex: a DNA-binding domain with a novel fold and mode of target site recognition

scientific article

Structure of the Kti11/Kti13 heterodimer and its double role in modifications of tRNA and eukaryotic elongation factor 2

scientific article

Structure of the NF-kappa B p50 homodimer bound to DNA

scientific article

Structure of the TFIIIC subcomplex τA provides insights into RNA polymerase III pre-initiation complex formation

scientific article published on 30 September 2020

Structure of the complex between adenylate kinase from Escherichia coli and the inhibitor Ap5A refined at 1.9 A resolution. A model for a catalytic transition state

scientific article published on March 5, 1992

Structure of the human NF-kappa B p52 homodimer-DNA complex at 2.1Aresolution ⬇️

scientific article published on December 1, 1997

Structure of the τ60/Δτ91 Subcomplex of Yeast Transcription Factor IIIC: Insights into Preinitiation Complex Assembly

scientific article published on 01 October 2006

The Combination of X-Ray Crystallography and Cryo-Electron Microscopy Provides Insight into the Overall Architecture of the Dodecameric Rvb1/Rvb2 Complex

scientific article published on 8 January 2016

The Crystal Structure of the Drosophila Germline Inducer Oskar Identifies Two Domains with Distinct Vasa Helicase- and RNA-Binding Activities

scientific article

The Elongator subcomplex Elp456 is a hexameric RecA-like ATPase

scientific article

The GCM domain is a Zn-coordinating DNA-binding domain

scientific journal article

The LOTUS domain is a conserved DEAD-box RNA helicase regulator essential for the recruitment of Vasa to the germ plasm and nuage

scientific article

The cryo-EM resolution revolution and transcription complexes

scientific article published on 14 July 2018

The cryo-EM structure of a 12-subunit variant of RNA polymerase I reveals dissociation of the A49-A34.5 heterodimer and rearrangement of subunit A12.2

scientific article published on 26 March 2019

The histone fold subunits of Drosophila CHRAC facilitate nucleosome sliding through dynamic DNA interactions.

scientific article published on November 2005

The histone octamer is invisible when NF-kappaB binds to the nucleosome

scientific article published on 21 July 2004

The signalling conformation of the insulin receptor ectodomain

scientific article published in Nature Communications

The structure of the NF-kappa B p50:DNA-complex: a starting point for analyzing the Rel family.

scientific article

Three-dimensional structure of the Stat3β homodimer bound to DNA ⬇️

scientific article published on July 9, 1998

Transcribing RNA polymerase III observed by electron cryomicroscopy

scientific article

Unleashing the Power of ASH1L Methyltransferase

scientific article published on 01 May 2019

WD40 proteins propel cellular networks.

scientific article

Xlink Analyzer: software for analysis and visualization of cross-linking data in the context of three-dimensional structures

scientific article published on 7 February 2015

List of works by Christoph W Müller

A bromodomain-DNA interaction facilitates acetylation-dependent bivalent nucleosome recognition by the BET protein BRDT.

A firm hand on NFkappaB: structures of the IkappaBalpha-NFkappaB complex.

A synthetic biology approach to probing nucleosome symmetry.

A systematic screen for protein-lipid interactions in Saccharomyces cerevisiae

An integrated approach for genome annotation of the eukaryotic thermophile Chaetomium thermophilum

Analyzing RNA polymerase III by electron cryomicroscopy.

Architecture of CRM1/Exportin1 suggests how cooperativity is achieved during formation of a nuclear export complex

Architecture of TFIIIC and its role in RNA polymerase III pre-initiation complex assembly.

Architecture of the yeast Elongator complex

Automated structure modeling of large protein assemblies using crosslinks as distance restraints

Bacterial expression, purification, and crystallization of tyrosine phosphorylated STAT proteins

Chromatin-modifying Complex Component Nurf55/p55 Associates with Histones H3 and H4 and Polycomb Repressive Complex 2 Subunit Su(z)12 through Partially Overlapping Binding Sites

Comparison of two different DMA-binding modes of the NF-κB p50 homodimer

Complex Interdependence Regulates Heterotypic Transcription Factor Distribution and Coordinates Cardiogenesis

Conformational flexibility of RNA polymerase III during transcriptional elongation.

Cooperative binding of two acetylation marks on a histone tail by a single bromodomain

Cryo-EM structures of human RNA polymerase I

Crystal structure and functional analysis of a nucleosome recognition module of the remodeling factor ISWI

Crystal structure of the 14-subunit RNA polymerase I

Crystal structure of the M1 protein-binding domain of the influenza A virus nuclear export protein (NEP/NS2)

Crystal structure of the ankyrin repeat domain of Bcl-3: a unique member of the IkappaB protein family.

Crystallographic structure of the T domain-DNA complex of the Brachyury transcription factor

Delineation of two functional regions of transcription factor TFIIB.

Different TBX5 interactions in heart and limb defined by Holt-Oram syndrome mutations

Du nouveau dans la compréhension de la reprogrammation postméiotique du génome mâle

Editorial overview: Protein-nucleic acid interactions: An expanding universe

Elongator: transcriptional or translational regulator?

Engineering of diffraction-quality crystals of the NF-κB P52 homodimer:DNA complex

Expression, proteolytic analysis, reconstitution, and crystallization of the τ60/τ91 subcomplex of yeast TFIIIC

Expression, purification, crystallization and preliminary X-ray analysis of a C-terminal fragment of the Epstein-Barr virus ZEBRA protein

Full repression of RNA polymerase III transcription requires interaction between two domains of its negative regulator Maf1

HDAC6-p97/VCP controlled polyubiquitin chain turnover

Histone H2A monoubiquitination promotes histone H3 methylation in Polycomb repression

Human importin alpha and RNA do not compete for binding to influenza A virus nucleoprotein.

In-cell architecture of the nuclear pore and snapshots of its turnover

Induced-fit movements in adenylate kinases

Insights into the Function of the CRM1 Cofactor RanBP3 from the Structure of Its Ran-Binding Domain

Insights into transcription initiation and termination from the electron microscopy structure of yeast RNA polymerase III.

Interaction of influenza virus proteins with nucleosomes.

Karyopherin flexibility in nucleocytoplasmic transport

Mass spectrometry reveals stable modules in holo and apo RNA polymerases I and III.

Molecular Structures of Transcribing RNA Polymerase I.

Molecular architecture of polycomb repressive complexes

Molecular basis of tRNA recognition by the Elongator complex

Molecular insight into RNA polymerase I promoter recognition and promoter melting

Molecular mechanism of promoter opening by RNA polymerase III.

Molecular recognition of histone lysine methylation by the Polycomb group repressor dSfmbt

Molecular structures of unbound and transcribing RNA polymerase III.

Nuclear import factors importin α and importin β undergo mutually induced conformational changes upon association

Pervasive Protein Thermal Stability Variation during the Cell Cycle.

Preparation and Properties of Oligodeoxynucleotides Containing 5-Iodouracil and 5-Bromo- and 5-Iodocytosine

Protein–nucleic acid interactions: some assembly required

RNA polymerase I and III: similar yet unique

RNA polymerase III initiation on coligo DNA templates containing loops of variable sequence, size and nucleotide chemistry

RNA polymerase III-specific general transcription factor IIIC contains a heterodimer resembling TFIIF Rap30/Rap74

Recognizing and remodeling the nucleosome

Solution study of the NF-kappaB p50-DNA complex by UV laser protein-DNA cross-linking

Solving the NES problem ⬇️

Solving the RNA polymerase I structural puzzle

Specialization versus conservation: How Pol I and Pol III use the conserved architecture of the pre-initiation complex for specialized transcription

Structural Basis for the Activation of the Deubiquitinase Calypso by the Polycomb Protein ASX

Structural and Functional Characterization of a Phosphatase Domain within Yeast General Transcription Factor IIIC

Structural and functional analyses of methyl-lysine binding by the malignant brain tumour repeat protein Sex comb on midleg

Structural asymmetry in the eukaryotic Elongator complex

Structural basis for LEAFY floral switch function and similarity with helix-turn-helix proteins

Structural basis for RNA polymerase III transcription repression by Maf1

Structural basis for tRNA modification by Elp3 from Dehalococcoides mccartyi

Structural basis for targeting the chromatin repressor Sfmbt to Polycomb response elements

Structural basis of TBX5-DNA recognition: the T-box domain in its DNA-bound and -unbound form

Structural basis of lytic cycle activation by the Epstein-Barr virus ZEBRA protein

Structural insights into Elongator function ⬇️

Structural insights into transcription initiation by yeast RNA polymerase I.

Structure of a truncation mutant of the nuclear export factor CRM1 provides insights into the auto-inhibitory role of its C-terminal helix

Structure of an activated Dictyostelium STAT in its DNA-unbound form

Structure of importin-beta bound to the IBB domain of importin-alpha

Structure of the DNA-bound T-box domain of human TBX3, a transcription factor responsible for ulnar-mammary syndrome

Structure of the Drosophila nucleosome core particle highlights evolutionary constraints on the H2A-H2B histone dimer

Structure of the GCM domain-DNA complex: a DNA-binding domain with a novel fold and mode of target site recognition

Structure of the Kti11/Kti13 heterodimer and its double role in modifications of tRNA and eukaryotic elongation factor 2