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List of works by Castrense Savojardo

Are machine learning based methods suited to address complex biological problems? Lessons from CAGI-5 challenges

scientific article published on 18 June 2019

Assessing computational predictions of the phenotypic effect of cystathionine-beta-synthase variants

scientific article published on 03 September 2019

Assessing predictions of the impact of variants on splicing in CAGI5

scientific article published on 19 August 2019

Assessment of blind predictions of the clinical significance of BRCA1 and BRCA2 variants

scientific article published on 23 August 2019

Assessment of methods for predicting the effects of PTEN and TPMT protein variants

scientific article published on 03 July 2019

Assessment of predicted enzymatic activity of α-N-acetylglucosaminidase variants of unknown significance for CAGI 2016

scientific article published on 01 September 2019

BCov: a method for predicting β-sheet topology using sparse inverse covariance estimation and integer programming.

scientific article

BETAWARE: a machine-learning tool to detect and predict transmembrane beta-barrel proteins in prokaryotes

scientific article

BUSCA: an integrative web server to predict subcellular localization of proteins.

scientific article published in July 2018

Computer-based prediction of mitochondria-targeting peptides

scientific article published on January 2015

DeepMito: accurate prediction of protein sub-mitochondrial localization using convolutional neural networks

scientific article published on 01 January 2020

DeepSig: deep learning improves signal peptide detection in proteins

scientific article

Evaluating the predictions of the protein stability change upon single amino acid substitutions for the FXN CAGI5 challenge

scientific article published on 12 July 2019

Functional and Structural Features of Disease-Related Protein Variants.

scientific article

Grammatical-Restrained Hidden Conditional Random Fields for Bioinformatics applications

scientific article published on 22 October 2009

Highlighting Human Enzymes Active in Different Metabolic Pathways and Diseases: The Case Study of EC 1.2.3.1 and EC 2.3.1.9.

scientific article published on 29 July 2020

INPS-MD: a web server to predict stability of protein variants from sequence and structure

scientific article published on 10 April 2016

INPS: predicting the impact of non-synonymous variations on protein stability from sequence.

scientific article

ISPRED4: interaction sites PREDiction in protein structures with a refining grammar model.

scientific article published on 27 January 2017

Improving the detection of transmembrane β-barrel chains with N-to-1 extreme learning machines

scientific article published on October 3, 2011

Improving the prediction of disulfide bonds in Eukaryotes with machine learning methods and protein subcellular localization.

scientific article published on 29 June 2011

Large scale analysis of protein stability in OMIM disease related human protein variants

scientific article

Large-scale prediction and analysis of protein sub-mitochondrial localization with DeepMito

scientific article published on 16 September 2020

Machine-Learning Methods to Predict Protein Interaction Sites in Folded Proteins

scholarly article by Castrense Savojardo et al published 2012 in Lecture Notes in Computer Science

MemPype: a pipeline for the annotation of eukaryotic membrane proteins

scientific article

On the biases in predictions of protein stability changes upon variations: the INPS test case

article

Performance of computational methods for the evaluation of pericentriolar material 1 missense variants in CAGI-5

scientific article published on 17 August 2019

Prediction of disulfide connectivity in proteins with machine-learning methods and correlated mutations.

scientific article

Prediction of the Bonding State of Cysteine Residues in Proteins with Machine-Learning Methods

scholarly article by Castrense Savojardo et al published 2011 in Lecture Notes in Computer Science

SChloro: directing Viridiplantae proteins to six chloroplastic sub-compartments

scientific article published on February 2017

TPpred2: improving the prediction of mitochondrial targeting peptide cleavage sites by exploiting sequence motifs.

scientific article

TPpred3 detects and discriminates mitochondrial and chloroplastic targeting peptides in eukaryotic proteins

scientific article

Testing the Capability of Embedding-Based Alignments on the GST Superfamily Classification: The Role of Protein Length

scientific article published in 2024

The prediction of organelle-targeting peptides in eukaryotic proteins with Grammatical-Restrained Hidden Conditional Random Fields.

scientific article published on 21 February 2013

eDGAR: a database of Disease-Gene Associations with annotated Relationships among genes

scientific article published on 11 August 2017