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List of works by Marleen Keyaerts

123I-2-iodo-tyrosine, a new tumour imaging agent: human biodistribution, dosimetry and initial clinical evaluation in glioma patients.

scientific article

A Comprehensive Analysis of Baseline Clinical Characteristics and Biomarkers Associated with Outcome in Advanced Melanoma Patients Treated with Pembrolizumab

scientific article published on 06 January 2021

A versatile T cell-based assay to assess therapeutic antigen-specific PD-1-targeted approaches.

scientific article published on 12 June 2018

Adjuvant-Enhanced mRNA Vaccines

scientific article

Agenesis of the pubic symphysis detected with SPECT-CT

scientific article published on 01 March 2011

Air leaks localized with lung ventilation SPECT.

scientific article published in December 2012

Anti-human PD-L1 Nanobody for Immuno-PET Imaging: Validation of a Conjugation Strategy for Clinical Translation

scientific article published on 29 September 2020

Antigen-presenting cell-targeted lentiviral vectors do not support the development of productive T-cell effector responses: implications for in vivo targeted vaccine delivery.

scientific article published on 25 May 2017

Bioluminescence imaging: looking beyond the light.

scientific article published on 08 February 2012

Clinical Translation of [68Ga]Ga-NOTA-anti-MMR-sdAb for PET/CT Imaging of Protumorigenic Macrophages

scientific article published on 01 October 2019

Comparison of the biodistribution and tumor targeting of two 99mTc-labeled anti-EGFR nanobodies in mice, using pinhole SPECT/micro-CT.

scientific article

Computer-aided detection and segmentation of malignant melanoma lesions on whole-body <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" altimg="si2.svg"><mml:msup><mml:mrow /><mml:mn>18</mml:mn></mml:msup></mml:math>F-FDG PET/CT using an inte

scientific article published on 22 May 2022

Correlation between epidermal growth factor receptor-specific nanobody uptake and tumor burden: a tool for noninvasive monitoring of tumor response to therapy

scientific article published on October 2011

Dynamic bioluminescence imaging for quantitative tumour burden assessment using IV or IP administration of D: -luciferin: effect on intensity, time kinetics and repeatability of photon emission.

scientific article published on 4 January 2008

Evaluating a Single Domain Antibody Targeting Human PD-L1 as a Nuclear Imaging and Therapeutic Agent

scientific article published on 21 June 2019

Genome-wide computational analysis reveals cardiomyocyte-specific transcriptional Cis-regulatory motifs that enable efficient cardiac gene therapy

scientific article published on 8 September 2014

HIV-1 lentiviral vector immunogenicity is mediated by Toll-like receptor 3 (TLR3) and TLR7.

scientific article

Inhibition of firefly luciferase by general anesthetics: effect on in vitro and in vivo bioluminescence imaging

scientific article (publication date: 2012)

Intra-individual comparison of the human biodistribution and dosimetry of the D and L isomers of 2-[123I]iodo-phenylalanine

scientific article published on 01 October 2007

Labeling of Anti-HER2 Nanobodies with Astatine-211: Optimization and the Effect of Different Coupling Reagents on Their in Vivo Behavior

scientific article published on 03 July 2019

Next-generation muscle-directed gene therapy by in silico vector design

scientific article published in Nature Communications

Non-invasive assessment of murine PD-L1 levels in syngeneic tumor models by nuclear imaging with nanobody tracers

scientific article published on 30 March 2017

Noninvasive Imaging of the Immune Checkpoint LAG-3 Using Nanobodies, from Development to Pre-Clinical Use

scientific article published on 29 September 2019

Noninvasive imaging of the PD-1:PD-L1 immune checkpoint: Embracing nuclear medicine for the benefit of personalized immunotherapy.

scientific article published on 7 June 2018

Perforin and Granzyme B Expressed by Murine Myeloid-Derived Suppressor Cells: A Study on Their Role in Outgrowth of Cancer Cells

scientific article published on 11 June 2019

Phase I Study of 68Ga-HER2-Nanobody for PET/CT Assessment of HER2 Expression in Breast Carcinoma.

scientific article

Plasma protein binding of luciferase substrates influences sensitivity and accuracy of bioluminescence imaging

scientific article published on February 2011

Preclinical Targeted α- and β--Radionuclide Therapy in HER2-Positive Brain Metastasis Using Camelid Single-Domain Antibodies

scientific article published on 21 April 2020

Preliminary in vivo evaluation of [131I]-2-iodo-D-phenylalanine as a potential radionuclide therapeutic agent in R1M-fluc rhabdomyosarcoma tumor-bearing NuNu mice using bioluminescent imaging.

scientific article published in April 2010

Regional quantitative analysis of small animal myocardial sympathetic innervation and initial application in streptozotocin induced diabetes.

scientific article published in July 2009

Same-Day Imaging Using Small Proteins: Clinical Experience and Translational Prospects in Oncology

scientific article published on 15 March 2018

Selective spleen SPECT/CT

scientific article published on 01 November 2011

Single Domain Antibody-Mediated Blockade of Programmed Death-Ligand 1 on Dendritic Cells Enhances CD8 T-cell Activation and Cytokine Production

scientific article published on 07 August 2019

Synthesis, preclinical validation, dosimetry, and toxicity of 68Ga-NOTA-anti-HER2 Nanobodies for iPET imaging of HER2 receptor expression in cancer

scientific article published on 13 March 2013

TNF-α-Secreting Lung Tumor-Infiltrated Monocytes Play a Pivotal Role During Anti-PD-L1 Immunotherapy

scientific article published on 14 April 2022

Targeted alpha therapy using short-lived alpha-particles and the promise of nanobodies as targeting vehicle.

scientific article published on 04 May 2016

The Next-Generation Immune Checkpoint LAG-3 and Its Therapeutic Potential in Oncology: Third Time's a Charm

scientific article published on 23 December 2020

The Road to Personalized Myeloma Medicine: Patient-specific Single-domain Antibodies for Anti-idiotypic Radionuclide Therapy

scientific article published in January 2022

The role of chemotherapy in the treatment of low-grade glioma. A review of the literature.

scientific article

Theranostics in immuno-oncology using nanobody derivatives

scientific article published on 15 October 2019

Undetectable circulating tumor DNA (ctDNA) levels correlate with favorable outcome in metastatic melanoma patients treated with anti-PD1 therapy

scientific article published on 05 September 2019

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